Click here to switch to the map view.

The map label for this gene is corC [H]

Identifier: 82703811

GI number: 82703811

Start: 3102283

End: 3103119

Strand: Direct

Name: corC [H]

Synonym: Nmul_A2698

Alternate gene names: 82703811

Gene position: 3102283-3103119 (Clockwise)

Preceding gene: 82703810

Following gene: 82703812

Centisome position: 97.43

GC content: 52.45

Gene sequence:

>837_bases
ATGGATGATCCTCCCCAACCTGGCTGGCTGGAACGCATAAGCGGCATGCTCCTGCGGGAACCGGGGAATCGGGTCCAATT
GATGGCCCTGCTGCATGCGGCGTACGAACGCAATTTATTCGATTCCGATGCGTTGAGCATGATAGAAGGAGTAATACAGG
TATCAGAGATCCAGGCACGCGACATCATGGTTCCCCGCTCGCAGATGGATGTCATCGACATCAGCGATCCGCCCGAGAAA
TTCATCCCCGAGGTGATCGAGAAAGCGCATTCGCGTTTTCCGGTTACCGAAAATGACAAAAATAATGTTATCGGTATATT
GCTGGCAAAGGACCTGTTGCGGTATTACGCGGCGGAGGAAGAGTTTGACGTGCGCGACATGTTGCGGCCGGTGGTATTCA
TTCCTGAATCCAAGCGCCTCAATGTCCTGCTTCGGGACTTTCGTACCAATCGCAATCACATCGCAATCGTCGTGGACGAG
TATGGTGGAGTTGCAGGACTGCTGACGATTGAAGACGTGCTGGAGCAGATTGTCGGCGATATCGAGGATGAACATGATTT
CGACGAGGTGGAAGACAACATTGTGCAGACGCCAAGCGGCCATTACCGGGTCAAGGCGATTACCGAGATCGCGGATTTCA
ATGAAAGACTTGAAACGGAATTAAACGAATCCGACTATGATACGATCGGAGGTCTGGTCCTGCACGAATTTGGACGCTTG
CCGAAACGAGGTGAATCAGTCATTGTCGGAGGTTTCAAGTTCACGGTGCTTCGCGCGGACAGCCGCAGATTGCACACCTT
GCTGGTGGAAAGAAGCAACGGCCAGATCGAGCAATAG

Upstream 100 bases:

>100_bases
GCTGGCGGAAGCGGTTGATTGTGGATAATGCGAGCACAGTTGATGGCTGACGGCAAGATTTCAATTGATTGGATTTTTAT
GGCTATGTTGACTTTTACAA

Downstream 100 bases:

>100_bases
GATGCGGCAGGGTTTCAAAAAAATGGTTGAGATCAGACCGGGCAGGAATAAGTCCGGGATGCAGGATAACCTTGAAGCAA
GCAGTACAAACCCGGATCGA

Product: transporter-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MDDPPQPGWLERISGMLLREPGNRVQLMALLHAAYERNLFDSDALSMIEGVIQVSEIQARDIMVPRSQMDVIDISDPPEK
FIPEVIEKAHSRFPVTENDKNNVIGILLAKDLLRYYAAEEEFDVRDMLRPVVFIPESKRLNVLLRDFRTNRNHIAIVVDE
YGGVAGLLTIEDVLEQIVGDIEDEHDFDEVEDNIVQTPSGHYRVKAITEIADFNERLETELNESDYDTIGGLVLHEFGRL
PKRGESVIVGGFKFTVLRADSRRLHTLLVERSNGQIEQ

Sequences:

>Translated_278_residues
MDDPPQPGWLERISGMLLREPGNRVQLMALLHAAYERNLFDSDALSMIEGVIQVSEIQARDIMVPRSQMDVIDISDPPEK
FIPEVIEKAHSRFPVTENDKNNVIGILLAKDLLRYYAAEEEFDVRDMLRPVVFIPESKRLNVLLRDFRTNRNHIAIVVDE
YGGVAGLLTIEDVLEQIVGDIEDEHDFDEVEDNIVQTPSGHYRVKAITEIADFNERLETELNESDYDTIGGLVLHEFGRL
PKRGESVIVGGFKFTVLRADSRRLHTLLVERSNGQIEQ
>Mature_278_residues
MDDPPQPGWLERISGMLLREPGNRVQLMALLHAAYERNLFDSDALSMIEGVIQVSEIQARDIMVPRSQMDVIDISDPPEK
FIPEVIEKAHSRFPVTENDKNNVIGILLAKDLLRYYAAEEEFDVRDMLRPVVFIPESKRLNVLLRDFRTNRNHIAIVVDE
YGGVAGLLTIEDVLEQIVGDIEDEHDFDEVEDNIVQTPSGHYRVKAITEIADFNERLETELNESDYDTIGGLVLHEFGRL
PKRGESVIVGGFKFTVLRADSRRLHTLLVERSNGQIEQ

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=206, Percent_Identity=33.0097087378641, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI94681046, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786879, Length=253, Percent_Identity=43.0830039525692, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI87082033, Length=247, Percent_Identity=30.7692307692308, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693175, Length=214, Percent_Identity=28.5046728971963, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790664, Length=229, Percent_Identity=28.82096069869, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788119, Length=222, Percent_Identity=31.0810810810811, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31690; Mature: 31690

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDPPQPGWLERISGMLLREPGNRVQLMALLHAAYERNLFDSDALSMIEGVIQVSEIQAR
CCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DIMVPRSQMDVIDISDPPEKFIPEVIEKAHSRFPVTENDKNNVIGILLAKDLLRYYAAEE
HEECCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHCCC
EFDVRDMLRPVVFIPESKRLNVLLRDFRTNRNHIAIVVDEYGGVAGLLTIEDVLEQIVGD
CCCHHHHHCCEEECCCCCCHHHHHHHHCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHC
IEDEHDFDEVEDNIVQTPSGHYRVKAITEIADFNERLETELNESDYDTIGGLVLHEFGRL
CCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
PKRGESVIVGGFKFTVLRADSRRLHTLLVERSNGQIEQ
CCCCCEEEEECEEEEEEECCCCEEEEHEEECCCCCCCC
>Mature Secondary Structure
MDDPPQPGWLERISGMLLREPGNRVQLMALLHAAYERNLFDSDALSMIEGVIQVSEIQAR
CCCCCCCCHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
DIMVPRSQMDVIDISDPPEKFIPEVIEKAHSRFPVTENDKNNVIGILLAKDLLRYYAAEE
HEECCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHCCC
EFDVRDMLRPVVFIPESKRLNVLLRDFRTNRNHIAIVVDEYGGVAGLLTIEDVLEQIVGD
CCCHHHHHCCEEECCCCCCHHHHHHHHCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHC
IEDEHDFDEVEDNIVQTPSGHYRVKAITEIADFNERLETELNESDYDTIGGLVLHEFGRL
CCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
PKRGESVIVGGFKFTVLRADSRRLHTLLVERSNGQIEQ
CCCCCEEEEECEEEEEEECCCCEEEEHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]