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The map label for this gene is dsbD [H]

Identifier: 82703796

GI number: 82703796

Start: 3082572

End: 3084536

Strand: Reverse

Name: dsbD [H]

Synonym: Nmul_A2683

Alternate gene names: 82703796

Gene position: 3084536-3082572 (Counterclockwise)

Preceding gene: 82703797

Following gene: 82703795

Centisome position: 96.87

GC content: 56.13

Gene sequence:

>1965_bases
ATGCCCCTGAACCGATATAGCCGATATTCCCTGCTGTTTCTCTGCCTTTTCAGCACCAGCGTCTTTGCGGAAGAAGGAAA
AACTTCCGGATTTCTTTCGGGTTTGCAGCAACTGCGCTCGACCTTGGGCCAGGATCAGGAGGAGCAGGAATTGCTGCCCC
CTGACGAGGCTTTCAAGCTGAAGGTTAAGGCACGGGACGCAAATACGCTTGTGGCGCAGTTCGAGCCGGCGAAGAACTAT
TATCTTTACAAGGATAAGGTTGCGTTCAAACCGCAGACCCCCGGAACCACTGTCGAAAACATCTCTCTCCCGCAGGGAGA
GATGAAAAGCGATGTGACCTTTGGGGAGGTCGAGGTTTTTAACGAGCCGTTTGAAGCATTGATTTCCCTGAAGCGGACCG
CGCCCTCTGGCGACAAGCTGACGCTTGTTGCCACTTATCAGGGTTGCAACGAGCCCATCGGTGTCTGCTATGCGCCCATA
AGCAAGGTAATCGATCTGACGCTGCCGGTTGCAAAGGCAGCGGCCGGAGCGGTCGCCAATGCAATGAGCGCCGATGCATC
CGCCGCAACAGGTTCCGCTGGAGAACGCCTTGATGCAACTGACGAGTTGTTCCAGTCGAAGGATGGTTCGGCCGCCATCG
AGACGGAATCGTTGGAAATCGAGAGAATGTTCCAGACCGGCAACTTCTGGCTGATTCTAACCGGCTTCTTCGGTATCGGC
CTGCTCCTCTCCTTTACTCCCTGTGTATTTCCCATGTTCCCCATTCTATCCGGCATTATCGCCAAGGGGGGGCAGCACGT
TACCAAGCAGCGCGGATTCATCCTGGCCCTGGCCTACGTGCTCGGAATGGCCATTACCTATGCTATCGCCGGGGTCGCAG
CGGGACTCTCCGGAGCAATGCTGTCGGCGACCCTGCAGAATGCCTGGGTACTGGGCGCGTTCGCGCTGATCTTTGTAACA
CTCGCATTTTCCATGTTCGGGTTCTATGAGCTGCAGCTCCCCACCTTTTTCCAGAGCAAGATTTCGGAAGAGGCTGGACA
TCTCAAAGGGGGACACCTTACGAGTGTATTCGGCATGGGCGCCTTGTCCGCACTGATTGTCGGACCGTGTGTGGCAGCGC
CTCTTGCGGGCGCGCTGCTGTACATCAGCCAGACACGGGATGTAGTGCTCGGAGGCTCGGCGCTCTTTGCCATGGCGCTG
GGCATGGGCCTGCCCTTGCTGTTGCTGGGCGCCTCCGCCGGCGCCCTCCTGCCGAAAGCAGGTGCATGGATGGAAGGAGT
CAAGCAGTCGTTCGGGGTATTGCTGCTGGGGGTGGCAATATGGCTGATATCCCCGGTGATTCCTGCTGTGGTGCACATGC
TGCTATGGGCCGCCCTGCTGATCGTGTCGGCCATTTACCTGCATGCGGTTGACCCGCTGCGGCCGGATGCTTCCGGTCCC
CAGAAATTCCTCAAGGGGATAGGCATGATTGCCCTGCTGACGGGCATCGCGTTGCTCGTCGGCGTGTTTTCCGGCAGCCG
CGATATTCTGCAACCTCTTTCAAAGCTGAATATTTCAGCGGCTGGCATGGAAGGGGCAAAAAAGGACGGTCTCAACTCAA
ACGAGCATTTGCCATTCCAGAGAGTAAAGTCGGTAGCGGAACTGAATCAGCAGATCCTCCAGTCGAGAAACAAATACGTA
ATGCTGGATTTTTATGCAGACTGGTGCGTCTCCTGCAAGGAAATGGAGCGTTTCACCTTTACCGACCCAGCTGTCCAGGC
ACGATTGAAAGACGTTGTGCTGCTGCAGGTTGATGTGACAGCAGGTACGCCCGAGGACATGGAGCTTCTCAAGCGCTTCA
AGCTGTTCGGGCCGCCGGCTATTCTCTTCATGGACAAAGAGGGACGTCAAGTTCCCAACGTCAAAATCATCGGTTATCAG
GATACCCCTGCTTTTCTGAAGATACTCAACGCGGTGCTGATCTAG

Upstream 100 bases:

>100_bases
ATCATTGCTGTCCCAATAAGCAGCGGATTGCCCGCATATCTGCATTGGATTTCCGGCGAAACGTCGAATCCGGATAAAAA
TTGAAGAGAATCTGGTTGTC

Downstream 100 bases:

>100_bases
CTTTCCCCCAGCAGCGTAATTTAATTGATCCGGAGTGCGCACAGGCAACCGAACTCGTGAGTTGCGGTGGCCGGGTCAGG
ATTTGAAGCTTATTTTTCTC

Product: protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 654; Mature: 653

Protein sequence:

>654_residues
MPLNRYSRYSLLFLCLFSTSVFAEEGKTSGFLSGLQQLRSTLGQDQEEQELLPPDEAFKLKVKARDANTLVAQFEPAKNY
YLYKDKVAFKPQTPGTTVENISLPQGEMKSDVTFGEVEVFNEPFEALISLKRTAPSGDKLTLVATYQGCNEPIGVCYAPI
SKVIDLTLPVAKAAAGAVANAMSADASAATGSAGERLDATDELFQSKDGSAAIETESLEIERMFQTGNFWLILTGFFGIG
LLLSFTPCVFPMFPILSGIIAKGGQHVTKQRGFILALAYVLGMAITYAIAGVAAGLSGAMLSATLQNAWVLGAFALIFVT
LAFSMFGFYELQLPTFFQSKISEEAGHLKGGHLTSVFGMGALSALIVGPCVAAPLAGALLYISQTRDVVLGGSALFAMAL
GMGLPLLLLGASAGALLPKAGAWMEGVKQSFGVLLLGVAIWLISPVIPAVVHMLLWAALLIVSAIYLHAVDPLRPDASGP
QKFLKGIGMIALLTGIALLVGVFSGSRDILQPLSKLNISAAGMEGAKKDGLNSNEHLPFQRVKSVAELNQQILQSRNKYV
MLDFYADWCVSCKEMERFTFTDPAVQARLKDVVLLQVDVTAGTPEDMELLKRFKLFGPPAILFMDKEGRQVPNVKIIGYQ
DTPAFLKILNAVLI

Sequences:

>Translated_654_residues
MPLNRYSRYSLLFLCLFSTSVFAEEGKTSGFLSGLQQLRSTLGQDQEEQELLPPDEAFKLKVKARDANTLVAQFEPAKNY
YLYKDKVAFKPQTPGTTVENISLPQGEMKSDVTFGEVEVFNEPFEALISLKRTAPSGDKLTLVATYQGCNEPIGVCYAPI
SKVIDLTLPVAKAAAGAVANAMSADASAATGSAGERLDATDELFQSKDGSAAIETESLEIERMFQTGNFWLILTGFFGIG
LLLSFTPCVFPMFPILSGIIAKGGQHVTKQRGFILALAYVLGMAITYAIAGVAAGLSGAMLSATLQNAWVLGAFALIFVT
LAFSMFGFYELQLPTFFQSKISEEAGHLKGGHLTSVFGMGALSALIVGPCVAAPLAGALLYISQTRDVVLGGSALFAMAL
GMGLPLLLLGASAGALLPKAGAWMEGVKQSFGVLLLGVAIWLISPVIPAVVHMLLWAALLIVSAIYLHAVDPLRPDASGP
QKFLKGIGMIALLTGIALLVGVFSGSRDILQPLSKLNISAAGMEGAKKDGLNSNEHLPFQRVKSVAELNQQILQSRNKYV
MLDFYADWCVSCKEMERFTFTDPAVQARLKDVVLLQVDVTAGTPEDMELLKRFKLFGPPAILFMDKEGRQVPNVKIIGYQ
DTPAFLKILNAVLI
>Mature_653_residues
PLNRYSRYSLLFLCLFSTSVFAEEGKTSGFLSGLQQLRSTLGQDQEEQELLPPDEAFKLKVKARDANTLVAQFEPAKNYY
LYKDKVAFKPQTPGTTVENISLPQGEMKSDVTFGEVEVFNEPFEALISLKRTAPSGDKLTLVATYQGCNEPIGVCYAPIS
KVIDLTLPVAKAAAGAVANAMSADASAATGSAGERLDATDELFQSKDGSAAIETESLEIERMFQTGNFWLILTGFFGIGL
LLSFTPCVFPMFPILSGIIAKGGQHVTKQRGFILALAYVLGMAITYAIAGVAAGLSGAMLSATLQNAWVLGAFALIFVTL
AFSMFGFYELQLPTFFQSKISEEAGHLKGGHLTSVFGMGALSALIVGPCVAAPLAGALLYISQTRDVVLGGSALFAMALG
MGLPLLLLGASAGALLPKAGAWMEGVKQSFGVLLLGVAIWLISPVIPAVVHMLLWAALLIVSAIYLHAVDPLRPDASGPQ
KFLKGIGMIALLTGIALLVGVFSGSRDILQPLSKLNISAAGMEGAKKDGLNSNEHLPFQRVKSVAELNQQILQSRNKYVM
LDFYADWCVSCKEMERFTFTDPAVQARLKDVVLLQVDVTAGTPEDMELLKRFKLFGPPAILFMDKEGRQVPNVKIIGYQD
TPAFLKILNAVLI

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=639, Percent_Identity=32.8638497652582, Blast_Score=337, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 70136; Mature: 70005

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNRYSRYSLLFLCLFSTSVFAEEGKTSGFLSGLQQLRSTLGQDQEEQELLPPDEAFKL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEE
KVKARDANTLVAQFEPAKNYYLYKDKVAFKPQTPGTTVENISLPQGEMKSDVTFGEVEVF
EEEECCCCEEEEEECCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCHHCCCCCCHHHHH
NEPFEALISLKRTAPSGDKLTLVATYQGCNEPIGVCYAPISKVIDLTLPVAKAAAGAVAN
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMSADASAATGSAGERLDATDELFQSKDGSAAIETESLEIERMFQTGNFWLILTGFFGIG
HHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECHHHHHHHHHCCCEEEEHHHHHHHH
LLLSFTPCVFPMFPILSGIIAKGGQHVTKQRGFILALAYVLGMAITYAIAGVAAGLSGAM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LSATLQNAWVLGAFALIFVTLAFSMFGFYELQLPTFFQSKISEEAGHLKGGHLTSVFGMG
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHH
ALSALIVGPCVAAPLAGALLYISQTRDVVLGGSALFAMALGMGLPLLLLGASAGALLPKA
HHHHHHHHHHHHHHHHHHHEEEECCCCEEECCHHHHHHHHHCCCHHHHHCCCCCCCCCCC
GAWMEGVKQSFGVLLLGVAIWLISPVIPAVVHMLLWAALLIVSAIYLHAVDPLRPDASGP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
QKFLKGIGMIALLTGIALLVGVFSGSRDILQPLSKLNISAAGMEGAKKDGLNSNEHLPFQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCHH
RVKSVAELNQQILQSRNKYVMLDFYADWCVSCKEMERFTFTDPAVQARLKDVVLLQVDVT
HHHHHHHHHHHHHHCCCCEEEEEECHHHHHCHHHHHCCCCCCHHHHHHHCEEEEEEEEEC
AGTPEDMELLKRFKLFGPPAILFMDKEGRQVPNVKIIGYQDTPAFLKILNAVLI
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHC
>Mature Secondary Structure 
PLNRYSRYSLLFLCLFSTSVFAEEGKTSGFLSGLQQLRSTLGQDQEEQELLPPDEAFKL
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCEEE
KVKARDANTLVAQFEPAKNYYLYKDKVAFKPQTPGTTVENISLPQGEMKSDVTFGEVEVF
EEEECCCCEEEEEECCCCCEEEEECCEEECCCCCCCCCCCCCCCCCCHHCCCCCCHHHHH
NEPFEALISLKRTAPSGDKLTLVATYQGCNEPIGVCYAPISKVIDLTLPVAKAAAGAVAN
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMSADASAATGSAGERLDATDELFQSKDGSAAIETESLEIERMFQTGNFWLILTGFFGIG
HHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEECHHHHHHHHHCCCEEEEHHHHHHHH
LLLSFTPCVFPMFPILSGIIAKGGQHVTKQRGFILALAYVLGMAITYAIAGVAAGLSGAM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LSATLQNAWVLGAFALIFVTLAFSMFGFYELQLPTFFQSKISEEAGHLKGGHLTSVFGMG
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHH
ALSALIVGPCVAAPLAGALLYISQTRDVVLGGSALFAMALGMGLPLLLLGASAGALLPKA
HHHHHHHHHHHHHHHHHHHEEEECCCCEEECCHHHHHHHHHCCCHHHHHCCCCCCCCCCC
GAWMEGVKQSFGVLLLGVAIWLISPVIPAVVHMLLWAALLIVSAIYLHAVDPLRPDASGP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
QKFLKGIGMIALLTGIALLVGVFSGSRDILQPLSKLNISAAGMEGAKKDGLNSNEHLPFQ
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCHH
RVKSVAELNQQILQSRNKYVMLDFYADWCVSCKEMERFTFTDPAVQARLKDVVLLQVDVT
HHHHHHHHHHHHHHCCCCEEEEEECHHHHHCHHHHHCCCCCCHHHHHHHCEEEEEEEEEC
AGTPEDMELLKRFKLFGPPAILFMDKEGRQVPNVKIIGYQDTPAFLKILNAVLI
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]