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The map label for this gene is map [H]

Identifier: 82703745

GI number: 82703745

Start: 3014994

End: 3015794

Strand: Direct

Name: map [H]

Synonym: Nmul_A2632

Alternate gene names: 82703745

Gene position: 3014994-3015794 (Clockwise)

Preceding gene: 82703744

Following gene: 82703746

Centisome position: 94.68

GC content: 54.18

Gene sequence:

>801_bases
ATGACGGTGCATCTCAAATCCCCTGATGAAATAGAGAAAATGCGGGTAGCGGGCAGACTTGCATCGGAAGTGCTGGATTA
CATCGCGCCGTTCGTCAAGCCGGGAGTGACGACCGACGAGCTTGACAAGCTGTGTCACGATTACATGGTGAATGTGCAGG
ATACCGTTCCTGCACCGCTCAATTATGCCCCTCCGGGTTATTCGCCTTACCCGAAATCGATCTGCACCTCGGTCAACCAT
CAGGTTTGTCATGGTATACCGGGGCATAAGAGACTCAAATCCGGGGATATCGTCAATATCGATGTAACCGTCATCAAAGA
CGGATATCACGGTGATACCAGCCGGATGTATCTCATCGGCGAACCCGGCATCCAGGCCAAGCGCCTGTGCAAGGTAACCT
ATGAAGCAATGTGGCATGGTATTGAAATCATCAAGCCCGGAAAACGGTTGGGGGATATCGGCCACGCCATTCAGCAGTAT
GCGGAAGGCCATGGATACAGTGTAGTGCGGGAATTCTGCGGTCATGGAATCGGAGCAAAATTCCATGAAGAACCCCAGGT
GCTTCATTACGGTCGCGCCGGGACAGGGCTCGAACTCAAAGCCGGAATGATCTTCACGGTCGAGCCGATGATCAACGCCG
GCAAGCCGCAGATTCGCCAGCTGGCCGATGGCTGGACCATTGTCACAAAGGATCATAGTCTGTCGGCGCAATGGGAACAT
ACCGTGCTCGTCACGGAAACAGGATACGAAGTGTTGACACAGTCGGGTGGCACTCCGCCGCAGCCCACCCTCCATTCCTG
A

Upstream 100 bases:

>100_bases
TGACCTTGCTGCGGGCAAGCAAGTCTTGCAATAAGATATTTCCATCCTCATCATATAAGCTTTTCATTCAAATTTATCGG
CTCATGGCTCTGAAATCTGT

Downstream 100 bases:

>100_bases
CGACAATGAAGGGGCTGAATGCAAAACCTTTCAGCCACGAAGCGGTCAGGCAGAAGCTCCTGAGCGGTCGCGAGTCGTTG
CAGCGCCGCTACCACCAAAA

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTVHLKSPDEIEKMRVAGRLASEVLDYIAPFVKPGVTTDELDKLCHDYMVNVQDTVPAPLNYAPPGYSPYPKSICTSVNH
QVCHGIPGHKRLKSGDIVNIDVTVIKDGYHGDTSRMYLIGEPGIQAKRLCKVTYEAMWHGIEIIKPGKRLGDIGHAIQQY
AEGHGYSVVREFCGHGIGAKFHEEPQVLHYGRAGTGLELKAGMIFTVEPMINAGKPQIRQLADGWTIVTKDHSLSAQWEH
TVLVTETGYEVLTQSGGTPPQPTLHS

Sequences:

>Translated_266_residues
MTVHLKSPDEIEKMRVAGRLASEVLDYIAPFVKPGVTTDELDKLCHDYMVNVQDTVPAPLNYAPPGYSPYPKSICTSVNH
QVCHGIPGHKRLKSGDIVNIDVTVIKDGYHGDTSRMYLIGEPGIQAKRLCKVTYEAMWHGIEIIKPGKRLGDIGHAIQQY
AEGHGYSVVREFCGHGIGAKFHEEPQVLHYGRAGTGLELKAGMIFTVEPMINAGKPQIRQLADGWTIVTKDHSLSAQWEH
TVLVTETGYEVLTQSGGTPPQPTLHS
>Mature_265_residues
TVHLKSPDEIEKMRVAGRLASEVLDYIAPFVKPGVTTDELDKLCHDYMVNVQDTVPAPLNYAPPGYSPYPKSICTSVNHQ
VCHGIPGHKRLKSGDIVNIDVTVIKDGYHGDTSRMYLIGEPGIQAKRLCKVTYEAMWHGIEIIKPGKRLGDIGHAIQQYA
EGHGYSVVREFCGHGIGAKFHEEPQVLHYGRAGTGLELKAGMIFTVEPMINAGKPQIRQLADGWTIVTKDHSLSAQWEHT
VLVTETGYEVLTQSGGTPPQPTLHS

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=252, Percent_Identity=46.8253968253968, Blast_Score=238, Evalue=4e-63,
Organism=Homo sapiens, GI40385867, Length=253, Percent_Identity=39.5256916996047, Blast_Score=195, Evalue=3e-50,
Organism=Escherichia coli, GI1786364, Length=254, Percent_Identity=59.8425196850394, Blast_Score=327, Evalue=4e-91,
Organism=Escherichia coli, GI1788728, Length=214, Percent_Identity=24.2990654205607, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71996291, Length=259, Percent_Identity=43.2432432432432, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323273, Length=253, Percent_Identity=43.8735177865613, Blast_Score=211, Evalue=7e-56,
Organism=Drosophila melanogaster, GI21355531, Length=254, Percent_Identity=46.8503937007874, Blast_Score=230, Evalue=7e-61,
Organism=Drosophila melanogaster, GI24583427, Length=251, Percent_Identity=40.6374501992032, Blast_Score=205, Evalue=3e-53,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29258; Mature: 29127

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHLKSPDEIEKMRVAGRLASEVLDYIAPFVKPGVTTDELDKLCHDYMVNVQDTVPAPL
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
NYAPPGYSPYPKSICTSVNHQVCHGIPGHKRLKSGDIVNIDVTVIKDGYHGDTSRMYLIG
CCCCCCCCCCCHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEE
EPGIQAKRLCKVTYEAMWHGIEIIKPGKRLGDIGHAIQQYAEGHGYSVVREFCGHGIGAK
CCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
FHEEPQVLHYGRAGTGLELKAGMIFTVEPMINAGKPQIRQLADGWTIVTKDHSLSAQWEH
CCCCCCEEEECCCCCCCEEECCEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCE
TVLVTETGYEVLTQSGGTPPQPTLHS
EEEEEECCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TVHLKSPDEIEKMRVAGRLASEVLDYIAPFVKPGVTTDELDKLCHDYMVNVQDTVPAPL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
NYAPPGYSPYPKSICTSVNHQVCHGIPGHKRLKSGDIVNIDVTVIKDGYHGDTSRMYLIG
CCCCCCCCCCCHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEEEE
EPGIQAKRLCKVTYEAMWHGIEIIKPGKRLGDIGHAIQQYAEGHGYSVVREFCGHGIGAK
CCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
FHEEPQVLHYGRAGTGLELKAGMIFTVEPMINAGKPQIRQLADGWTIVTKDHSLSAQWEH
CCCCCCEEEECCCCCCCEEECCEEEEECCCCCCCCHHHHHHHCCCEEEEECCCCCCCCCE
TVLVTETGYEVLTQSGGTPPQPTLHS
EEEEEECCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]