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The map label for this gene is yjeP [H]

Identifier: 82703735

GI number: 82703735

Start: 3007125

End: 3008363

Strand: Direct

Name: yjeP [H]

Synonym: Nmul_A2622

Alternate gene names: 82703735

Gene position: 3007125-3008363 (Clockwise)

Preceding gene: 82703734

Following gene: 82703736

Centisome position: 94.44

GC content: 55.13

Gene sequence:

>1239_bases
ATGCACTTCAACATTGAATTCCAGAGCCTGCTGAACAAACTGCTTGCTCATGCGCAGCAAGTCCCCGTCCTGTGGCAGCT
TGCTGTGTTGACTGCGGCCATGGGAATGGCGTGGTTGCTGCAAAGGCAGTTCATCCGGCGCGCTCCGGCGCGTGTCAATG
CCGGCGGGAAGTTAACCATCAGCGCACGCAGCCTGAGCCGGCTCCTGTTTCCATTTTTTGCGCTGGTCTTTACTGTCGTC
GGCAAGGGAGCGCTGGACTATTGGTACCCGACGCACCTGCTCAATATCATTATCCCGATTCTGTTCGCGCTCGTCCTGAT
CCGTGCCGCGGTCTACATGCTGCGCAAGGTATTTCGCCGCCAGGAGTGGCTCCGCCCGTGGGAACGATTCATCGGCTGGA
CGGTGTGGATAGGATTCGCGCTTTATATCACAGGGCTTTTGCCCGAAATTCTGGCCCTTCTCGACGACATTTCACTGCAT
GTCGGCAAGCAGCGTATTTCGATATTGCTGATCGCCCAGGGTTTCATCGCGTTCACCGTCAGCATGCTCGTGGCCGCCTC
GCTTGCAAGTTCGGTTGAAACCCGCATCATGATGGCGAGAGCGCTGAATATCAATCAGCGTGTCATCTTGTCGAAGATCA
GCCGCACCATTCTGATCATTATCGGAGTGTTGGTTGCGTTGCCCATGGTCGGCGTGGATATCACGTTTCTGTCCGTGTTT
GGAGGTGCACTCGGCGTCGGGCTCGGACTGGGATTGCAAAAGATCGCGAGTAACTACATCAGCGGGTTTATCATTCTCCT
GGACCATTCCCTCCATCTCGGCGATATAATCACGGTGGATAACCGCAAAGGCGAGGTGACCTCGCTCACCACGCGGTATG
TGGTGCTCAAGAGCGAAGAAGGTACCAATATCCTCATTCCCAATGACGTTTTCATTACTTCGGCTGTCATCAACCATCCC
TTCTCCGATCGCCGATTGCGCCTTGTCTTTCCGATGCGTATCAGCTACGACAGTCCGATCGAAGCCGCGATGAAAATCAT
GTCGGAAGCGGCAAAGAGGCGCCAGCAGATATTGGCCGAGCCTGCTCCCGCAGTGTATCTCAAGGAATTCGTCGATGGCG
GGATCGTTCTGGAACTCGTCGCATGGGTGGAAGAAGCGGAGAAGAATCTGCCTGCGCTACGGTCCGATATCAACCTCGAT
ATCTGGCGGACATTCGGAGAAAACGGGATCAAGCGTTGA

Upstream 100 bases:

>100_bases
ATGAGGGGAAAGTAGTTTACGCGTGCTAGAATCTGGCACGCCCATCCATTTATCCATTTGCCCATCCATTTCCGCCACTG
CCCCTCTTCTGTTTCAACGG

Downstream 100 bases:

>100_bases
CTGAGGGCTTTTCAACCACATCAGCCCCAACGGTCCGTTTATAGTTTCTGCCCCCTCCGCCGCCAGGTCGGGAACTGTCC
GGAACCCTGAGGCGGATGGT

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MHFNIEFQSLLNKLLAHAQQVPVLWQLAVLTAAMGMAWLLQRQFIRRAPARVNAGGKLTISARSLSRLLFPFFALVFTVV
GKGALDYWYPTHLLNIIIPILFALVLIRAAVYMLRKVFRRQEWLRPWERFIGWTVWIGFALYITGLLPEILALLDDISLH
VGKQRISILLIAQGFIAFTVSMLVAASLASSVETRIMMARALNINQRVILSKISRTILIIIGVLVALPMVGVDITFLSVF
GGALGVGLGLGLQKIASNYISGFIILLDHSLHLGDIITVDNRKGEVTSLTTRYVVLKSEEGTNILIPNDVFITSAVINHP
FSDRRLRLVFPMRISYDSPIEAAMKIMSEAAKRRQQILAEPAPAVYLKEFVDGGIVLELVAWVEEAEKNLPALRSDINLD
IWRTFGENGIKR

Sequences:

>Translated_412_residues
MHFNIEFQSLLNKLLAHAQQVPVLWQLAVLTAAMGMAWLLQRQFIRRAPARVNAGGKLTISARSLSRLLFPFFALVFTVV
GKGALDYWYPTHLLNIIIPILFALVLIRAAVYMLRKVFRRQEWLRPWERFIGWTVWIGFALYITGLLPEILALLDDISLH
VGKQRISILLIAQGFIAFTVSMLVAASLASSVETRIMMARALNINQRVILSKISRTILIIIGVLVALPMVGVDITFLSVF
GGALGVGLGLGLQKIASNYISGFIILLDHSLHLGDIITVDNRKGEVTSLTTRYVVLKSEEGTNILIPNDVFITSAVINHP
FSDRRLRLVFPMRISYDSPIEAAMKIMSEAAKRRQQILAEPAPAVYLKEFVDGGIVLELVAWVEEAEKNLPALRSDINLD
IWRTFGENGIKR
>Mature_412_residues
MHFNIEFQSLLNKLLAHAQQVPVLWQLAVLTAAMGMAWLLQRQFIRRAPARVNAGGKLTISARSLSRLLFPFFALVFTVV
GKGALDYWYPTHLLNIIIPILFALVLIRAAVYMLRKVFRRQEWLRPWERFIGWTVWIGFALYITGLLPEILALLDDISLH
VGKQRISILLIAQGFIAFTVSMLVAASLASSVETRIMMARALNINQRVILSKISRTILIIIGVLVALPMVGVDITFLSVF
GGALGVGLGLGLQKIASNYISGFIILLDHSLHLGDIITVDNRKGEVTSLTTRYVVLKSEEGTNILIPNDVFITSAVINHP
FSDRRLRLVFPMRISYDSPIEAAMKIMSEAAKRRQQILAEPAPAVYLKEFVDGGIVLELVAWVEEAEKNLPALRSDINLD
IWRTFGENGIKR

Specific function: Unknown

COG id: COG3264

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI2367355, Length=237, Percent_Identity=31.6455696202532, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786670, Length=169, Percent_Identity=31.9526627218935, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789291, Length=236, Percent_Identity=25.8474576271186, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 46092; Mature: 46092

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFNIEFQSLLNKLLAHAQQVPVLWQLAVLTAAMGMAWLLQRQFIRRAPARVNAGGKLTI
CCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
SARSLSRLLFPFFALVFTVVGKGALDYWYPTHLLNIIIPILFALVLIRAAVYMLRKVFRR
EHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEWLRPWERFIGWTVWIGFALYITGLLPEILALLDDISLHVGKQRISILLIAQGFIAFTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEHEEHHHHHHHHH
SMLVAASLASSVETRIMMARALNINQRVILSKISRTILIIIGVLVALPMVGVDITFLSVF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGALGVGLGLGLQKIASNYISGFIILLDHSLHLGDIITVDNRKGEVTSLTTRYVVLKSEE
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECCCCCCEEEEEEEEEEEECCC
GTNILIPNDVFITSAVINHPFSDRRLRLVFPMRISYDSPIEAAMKIMSEAAKRRQQILAE
CCEEECCCCHHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
PAPAVYLKEFVDGGIVLELVAWVEEAEKNLPALRSDINLDIWRTFGENGIKR
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MHFNIEFQSLLNKLLAHAQQVPVLWQLAVLTAAMGMAWLLQRQFIRRAPARVNAGGKLTI
CCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
SARSLSRLLFPFFALVFTVVGKGALDYWYPTHLLNIIIPILFALVLIRAAVYMLRKVFRR
EHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEWLRPWERFIGWTVWIGFALYITGLLPEILALLDDISLHVGKQRISILLIAQGFIAFTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEHEEHHHHHHHHH
SMLVAASLASSVETRIMMARALNINQRVILSKISRTILIIIGVLVALPMVGVDITFLSVF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGALGVGLGLGLQKIASNYISGFIILLDHSLHLGDIITVDNRKGEVTSLTTRYVVLKSEE
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECCCCCCEEEEEEEEEEEECCC
GTNILIPNDVFITSAVINHPFSDRRLRLVFPMRISYDSPIEAAMKIMSEAAKRRQQILAE
CCEEECCCCHHHHHHHHCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
PAPAVYLKEFVDGGIVLELVAWVEEAEKNLPALRSDINLDIWRTFGENGIKR
CCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 3042771 [H]