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The map label for this gene is rsmB [H]

Identifier: 82703733

GI number: 82703733

Start: 3005120

End: 3006391

Strand: Direct

Name: rsmB [H]

Synonym: Nmul_A2620

Alternate gene names: 82703733

Gene position: 3005120-3006391 (Clockwise)

Preceding gene: 82703732

Following gene: 82703734

Centisome position: 94.37

GC content: 55.19

Gene sequence:

>1272_bases
ATGACAATGCGTCTTACCCCTGCTCATCTCGACATGGCAACCGCTGCACTGCGCACTGTACTTCCACTGCAACGTCCGGC
TGATTCTTTGTTGCGGCATTTTTTCCAGGACAATCGGAAACTCGGCGTGCACGATCGCGCGTTCATCGCTGAAATCGTAT
TCGGTATTCTGCGCCACCGTTTTTTTCTGGAGCGCGTGGTGGAAATTGCCACACCTCGTTCGCTCCTGCTGGCGTATCTG
GCGAAATTCTCGGGAATGAACTTGCGCGAGCTGACGCCCCTGGTGAGTGAAACAGAAGCAAAACGGCTTGCGGAAATGAA
AGCAGTGTCGCTGGAATCGCAGCCCCTCGGCGTCCAGGCAGAATTTCCGGAGTGGCTGTTGGAAAAACTGCGGGAATTCA
TGGACGATGGAGCCATTCTTGACCTGGGCCGCTCGCTGCAAGCACCCGCACCCCTTGATCTGCGTGTCAATACGCAGCTT
GCGACGCGCGAGGAAGTTATCGAGCTGTTGAGAAAAGATGGAATCGAAGGCATGCCGACGCCCTACTCGCCCCTCGGTAT
CCGCCTTACCGGAAAGCCGGCGATCAACCGGCATGAAGCGTTCATGAGCGGCAAGATCGAAGTCCAGGATGAAAGCAGCC
AGCTGCTGGGTTATCTGCTTGCCCCCAGGCGCCGGGACATGGTAGTGGATTTCTGCGCGGGAGCGGGAGGAAAGTCGCTG
ATGCTGGGGGCGCTGATGTGTTCGCAGGGACGCATCTATGCTTTCGATAATTCGGAAAAGCGGCTGAACAATCTCAAGCC
CCGCCTCAAGCGTTCCGGCTTATCGAACCTCCATCCTCAGCTCATCGCCAATGAAAACGACATAAAGGTGAAACGGCTGG
CGGGAAAAATCGATCGGGTATTGGTGGATGCACCTTGCAGCGGGCTTGGAACCCTGCGACGAAACCCGGATCTGAAATGG
CGCCAGTCGCCGCAAAGCATCGAGGAACTCAAGTGCAAGCAAACCGCTATCCTGTCATCTGCGGCCAACTTGCTTAAACC
GGGTGGCAGGCTTGTTTATGCCACTTGCAGCTTTTTACCGGAAGAAAACCAGGAAATCGTTGAGAATTTTATTGCGAATA
ACCCCCGCTTCACCCTGTTGAATTGCGCCGAGTTATTGCGCCAGCAAAAAATCCCGCTCGACACCGGTGTGTTTATGCAA
CTCCTGCCCAGGCTGCACGGAACGGATGGTTTTTTTGCCGCCGCACTGGAATCAGGGAAGGCTCAAACATGA

Upstream 100 bases:

>100_bases
CCGGGCAGCGAGTGCCGTCTGCCCGAATCCTCCCTTTGCGCCTGCCTGTCCTGCTAAGGCGTGCTTTGCGTCCGCTTCTG
CCGAGCAGTATCGATAATTC

Downstream 100 bases:

>100_bases
TGTCACCAGGCCGTAGTCTCTCCGTGAAGCAGTATATGGCTGTCTGTCTTGCTGTACTCCTGACAACCTCTGCCGCAGCG
TTTGAACCCCCTTCCTATCG

Product: Fmu (Sun) NOL1/Nop2p

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTMRLTPAHLDMATAALRTVLPLQRPADSLLRHFFQDNRKLGVHDRAFIAEIVFGILRHRFFLERVVEIATPRSLLLAYL
AKFSGMNLRELTPLVSETEAKRLAEMKAVSLESQPLGVQAEFPEWLLEKLREFMDDGAILDLGRSLQAPAPLDLRVNTQL
ATREEVIELLRKDGIEGMPTPYSPLGIRLTGKPAINRHEAFMSGKIEVQDESSQLLGYLLAPRRRDMVVDFCAGAGGKSL
MLGALMCSQGRIYAFDNSEKRLNNLKPRLKRSGLSNLHPQLIANENDIKVKRLAGKIDRVLVDAPCSGLGTLRRNPDLKW
RQSPQSIEELKCKQTAILSSAANLLKPGGRLVYATCSFLPEENQEIVENFIANNPRFTLLNCAELLRQQKIPLDTGVFMQ
LLPRLHGTDGFFAAALESGKAQT

Sequences:

>Translated_423_residues
MTMRLTPAHLDMATAALRTVLPLQRPADSLLRHFFQDNRKLGVHDRAFIAEIVFGILRHRFFLERVVEIATPRSLLLAYL
AKFSGMNLRELTPLVSETEAKRLAEMKAVSLESQPLGVQAEFPEWLLEKLREFMDDGAILDLGRSLQAPAPLDLRVNTQL
ATREEVIELLRKDGIEGMPTPYSPLGIRLTGKPAINRHEAFMSGKIEVQDESSQLLGYLLAPRRRDMVVDFCAGAGGKSL
MLGALMCSQGRIYAFDNSEKRLNNLKPRLKRSGLSNLHPQLIANENDIKVKRLAGKIDRVLVDAPCSGLGTLRRNPDLKW
RQSPQSIEELKCKQTAILSSAANLLKPGGRLVYATCSFLPEENQEIVENFIANNPRFTLLNCAELLRQQKIPLDTGVFMQ
LLPRLHGTDGFFAAALESGKAQT
>Mature_422_residues
TMRLTPAHLDMATAALRTVLPLQRPADSLLRHFFQDNRKLGVHDRAFIAEIVFGILRHRFFLERVVEIATPRSLLLAYLA
KFSGMNLRELTPLVSETEAKRLAEMKAVSLESQPLGVQAEFPEWLLEKLREFMDDGAILDLGRSLQAPAPLDLRVNTQLA
TREEVIELLRKDGIEGMPTPYSPLGIRLTGKPAINRHEAFMSGKIEVQDESSQLLGYLLAPRRRDMVVDFCAGAGGKSLM
LGALMCSQGRIYAFDNSEKRLNNLKPRLKRSGLSNLHPQLIANENDIKVKRLAGKIDRVLVDAPCSGLGTLRRNPDLKWR
QSPQSIEELKCKQTAILSSAANLLKPGGRLVYATCSFLPEENQEIVENFIANNPRFTLLNCAELLRQQKIPLDTGVFMQL
LPRLHGTDGFFAAALESGKAQT

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=317, Percent_Identity=28.391167192429, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI76150623, Length=317, Percent_Identity=28.391167192429, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI270288818, Length=326, Percent_Identity=28.8343558282209, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI32698918, Length=252, Percent_Identity=26.5873015873016, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI8922322, Length=249, Percent_Identity=29.718875502008, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI270288816, Length=249, Percent_Identity=29.718875502008, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI23199998, Length=249, Percent_Identity=29.718875502008, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI39995082, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI301336155, Length=185, Percent_Identity=28.6486486486486, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI11545785, Length=206, Percent_Identity=30.5825242718447, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI2367212, Length=297, Percent_Identity=32.6599326599327, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081985, Length=311, Percent_Identity=28.6173633440514, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17536757, Length=324, Percent_Identity=25.6172839506173, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI115534021, Length=242, Percent_Identity=28.9256198347107, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71998419, Length=228, Percent_Identity=29.3859649122807, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25143471, Length=255, Percent_Identity=28.6274509803922, Blast_Score=79, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324268, Length=310, Percent_Identity=23.5483870967742, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319447, Length=291, Percent_Identity=28.1786941580756, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI22024126, Length=310, Percent_Identity=24.5161290322581, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21356579, Length=353, Percent_Identity=24.3626062322946, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21355201, Length=189, Percent_Identity=31.7460317460317, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356513, Length=291, Percent_Identity=28.5223367697594, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24668781, Length=291, Percent_Identity=28.5223367697594, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 47242; Mature: 47110

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRLTPAHLDMATAALRTVLPLQRPADSLLRHFFQDNRKLGVHDRAFIAEIVFGILRHR
CCEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FFLERVVEIATPRSLLLAYLAKFSGMNLRELTPLVSETEAKRLAEMKAVSLESQPLGVQA
HHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EFPEWLLEKLREFMDDGAILDLGRSLQAPAPLDLRVNTQLATREEVIELLRKDGIEGMPT
CCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCC
PYSPLGIRLTGKPAINRHEAFMSGKIEVQDESSQLLGYLLAPRRRDMVVDFCAGAGGKSL
CCCCCEEEEECCCCCCHHHHHHCCCEEEECCHHHHHHHHHCCCCCCHHHEECCCCCCHHH
MLGALMCSQGRIYAFDNSEKRLNNLKPRLKRSGLSNLHPQLIANENDIKVKRLAGKIDRV
HHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHE
LVDAPCSGLGTLRRNPDLKWRQSPQSIEELKCKQTAILSSAANLLKPGGRLVYATCSFLP
EEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
EENQEIVENFIANNPRFTLLNCAELLRQQKIPLDTGVFMQLLPRLHGTDGFFAAALESGK
CCCHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCC
AQT
CCC
>Mature Secondary Structure 
TMRLTPAHLDMATAALRTVLPLQRPADSLLRHFFQDNRKLGVHDRAFIAEIVFGILRHR
CEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FFLERVVEIATPRSLLLAYLAKFSGMNLRELTPLVSETEAKRLAEMKAVSLESQPLGVQA
HHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EFPEWLLEKLREFMDDGAILDLGRSLQAPAPLDLRVNTQLATREEVIELLRKDGIEGMPT
CCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCC
PYSPLGIRLTGKPAINRHEAFMSGKIEVQDESSQLLGYLLAPRRRDMVVDFCAGAGGKSL
CCCCCEEEEECCCCCCHHHHHHCCCEEEECCHHHHHHHHHCCCCCCHHHEECCCCCCHHH
MLGALMCSQGRIYAFDNSEKRLNNLKPRLKRSGLSNLHPQLIANENDIKVKRLAGKIDRV
HHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHE
LVDAPCSGLGTLRRNPDLKWRQSPQSIEELKCKQTAILSSAANLLKPGGRLVYATCSFLP
EEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
EENQEIVENFIANNPRFTLLNCAELLRQQKIPLDTGVFMQLLPRLHGTDGFFAAALESGK
CCCHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCC
AQT
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]