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The map label for this gene is yvrB [H]

Identifier: 82703727

GI number: 82703727

Start: 2999782

End: 3000771

Strand: Reverse

Name: yvrB [H]

Synonym: Nmul_A2614

Alternate gene names: 82703727

Gene position: 3000771-2999782 (Counterclockwise)

Preceding gene: 82703728

Following gene: 82703726

Centisome position: 94.24

GC content: 57.78

Gene sequence:

>990_bases
ATGACATCAGGCGCAGGCTTCAGACATTCGTATCCCCTGCTGCTGGTTCTCTTCGGCCTGCTGGCCATGGGCAGCCTTTT
CATCGGTTTGCTGTTCGGCAGCGTCCATATTCCGGTTTTCGGCGTCGTTCAAGCACTGCTGTCTTCAACCGACAGCATCT
CTCATCAGATTATCTGGCAACTTCGCCTGCCACGGGTACTGGCCGCCTTTGCCTGCGGCGGTCTTCTGGCGCTGGCGGGG
GCATTGTTGCAGGTTTTATTGCGCAATCCTCTCGCCGATCCATATATCCTGGGGGTTTCGGGGGGCGCAGCCGTAGGCGC
ACTCCTTGCCATGCTCCTCGGGTGGGGAACTCTGCTGACGAATCTGACGTCCCTAGCGGGAGCTTTGACGATCGTTGCCA
TTGTATTCGGCCTGAGTTTTCGCGCGGGCAACTGGAATCTTTACCGGCTGCTTCTGACTGGTGTGGTGTTGTCCGCTGGT
TGCGGGGCGCTCACAACGCTGATTCTTACCCTTGCGCCGGCGAGCGATGTCAAAGGCATGCTCTTCTGGTTGATGGGGGA
TGTTTCGCGTGCCGAAGAGCCATTGCCAGCCTGGGTAACGCTCATTCTCGTATCCGCCGTGAGCCTGCTTTTTTCCGGGA
GCCTGAACGTTTTGTCACTGGGTCAAATGAAGGCAAGAACTTTAGGCGTGGCCGTGCTACCGTTGCAAATAGGAATTTAT
TTTTGCGCATCGCTTGCCACCGTGGCGGCGTTGATGCTCGCGGGAGTCATCGGCTTCGTGGGCCTGATCGTACCGCATGC
GGTCCGCCTGCTGGGGGTCAGTAATTTTCGCTGGTTATTGCCTCTGGCGGTATTATTGGGGGGCAGCTTTCTCACGCTGG
CCGATACCCTGGGGCGGACGCTATGGGCCCCCCAACAGTTACCTGTGGGCGTATTGACCGCTTTGCTGGGCGTACCGATG
CTATTGCTGCTGCTTTCACGAAAACCCTGA

Upstream 100 bases:

>100_bases
CCTGCTGCCTAATGCTGAAACGACCCGACGGAAACCGGCAGTTGTTCCTATTCACCGCTGCTTTCTCCCAGTCGCGAGCA
TTGAATATCTGCGTACTGGC

Downstream 100 bases:

>100_bases
TCACTTCTGCCTCATGAACAGGCACCATCATGAGCCGATACCAGGCTATCATCACTAACGGCGTAAGGAATTTTCATCCT
GCCTACTTCGCCATGGTGAT

Product: transport system permease

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTSGAGFRHSYPLLLVLFGLLAMGSLFIGLLFGSVHIPVFGVVQALLSSTDSISHQIIWQLRLPRVLAAFACGGLLALAG
ALLQVLLRNPLADPYILGVSGGAAVGALLAMLLGWGTLLTNLTSLAGALTIVAIVFGLSFRAGNWNLYRLLLTGVVLSAG
CGALTTLILTLAPASDVKGMLFWLMGDVSRAEEPLPAWVTLILVSAVSLLFSGSLNVLSLGQMKARTLGVAVLPLQIGIY
FCASLATVAALMLAGVIGFVGLIVPHAVRLLGVSNFRWLLPLAVLLGGSFLTLADTLGRTLWAPQQLPVGVLTALLGVPM
LLLLLSRKP

Sequences:

>Translated_329_residues
MTSGAGFRHSYPLLLVLFGLLAMGSLFIGLLFGSVHIPVFGVVQALLSSTDSISHQIIWQLRLPRVLAAFACGGLLALAG
ALLQVLLRNPLADPYILGVSGGAAVGALLAMLLGWGTLLTNLTSLAGALTIVAIVFGLSFRAGNWNLYRLLLTGVVLSAG
CGALTTLILTLAPASDVKGMLFWLMGDVSRAEEPLPAWVTLILVSAVSLLFSGSLNVLSLGQMKARTLGVAVLPLQIGIY
FCASLATVAALMLAGVIGFVGLIVPHAVRLLGVSNFRWLLPLAVLLGGSFLTLADTLGRTLWAPQQLPVGVLTALLGVPM
LLLLLSRKP
>Mature_328_residues
TSGAGFRHSYPLLLVLFGLLAMGSLFIGLLFGSVHIPVFGVVQALLSSTDSISHQIIWQLRLPRVLAAFACGGLLALAGA
LLQVLLRNPLADPYILGVSGGAAVGALLAMLLGWGTLLTNLTSLAGALTIVAIVFGLSFRAGNWNLYRLLLTGVVLSAGC
GALTTLILTLAPASDVKGMLFWLMGDVSRAEEPLPAWVTLILVSAVSLLFSGSLNVLSLGQMKARTLGVAVLPLQIGIYF
CASLATVAALMLAGVIGFVGLIVPHAVRLLGVSNFRWLLPLAVLLGGSFLTLADTLGRTLWAPQQLPVGVLTALLGVPML
LLLLSRKP

Specific function: Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=280, Percent_Identity=40, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790740, Length=321, Percent_Identity=36.7601246105919, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790741, Length=329, Percent_Identity=34.9544072948328, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786805, Length=305, Percent_Identity=37.7049180327869, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786347, Length=281, Percent_Identity=34.1637010676157, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786804, Length=310, Percent_Identity=33.2258064516129, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34261; Mature: 34130

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGAGFRHSYPLLLVLFGLLAMGSLFIGLLFGSVHIPVFGVVQALLSSTDSISHQIIWQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHH
LRLPRVLAAFACGGLLALAGALLQVLLRNPLADPYILGVSGGAAVGALLAMLLGWGTLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
NLTSLAGALTIVAIVFGLSFRAGNWNLYRLLLTGVVLSAGCGALTTLILTLAPASDVKGM
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
LFWLMGDVSRAEEPLPAWVTLILVSAVSLLFSGSLNVLSLGQMKARTLGVAVLPLQIGIY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
FCASLATVAALMLAGVIGFVGLIVPHAVRLLGVSNFRWLLPLAVLLGGSFLTLADTLGRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHH
LWAPQQLPVGVLTALLGVPMLLLLLSRKP
HCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSGAGFRHSYPLLLVLFGLLAMGSLFIGLLFGSVHIPVFGVVQALLSSTDSISHQIIWQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHH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HCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]