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The map label for this gene is pilE1 [H]

Identifier: 82703590

GI number: 82703590

Start: 2828529

End: 2829047

Strand: Direct

Name: pilE1 [H]

Synonym: Nmul_A2475

Alternate gene names: 82703590

Gene position: 2828529-2829047 (Clockwise)

Preceding gene: 82703589

Following gene: 82703591

Centisome position: 88.83

GC content: 54.91

Gene sequence:

>519_bases
ATGCGTTTAACCAAGAAGGAGTTTTTTAGCATGAAGCAGGATCAGAAGGGCCTAACCTTGATCGAGTCAATGATGGTAGT
TGCCCTCATTGGCATCCTGGCGACGATCGCTATTCCACCTGCATTTCGGCTCTATGAGGACTCCCAGGCCCGCGCCCAGG
TAACCGAAGCGCTCGATCTTCTCGGCCGCGTTAAATCTCCTGTTGCCGCGTTTTATTCGGATAAGGGAAGATGGCCTACC
TCCGAAGAGTTCGACAATCTGGTGCCCGCACGGACCGGCAAGTATGTCGCGAGCCTCACGCCGGAATCCCGCGAAAAAGG
TTTTGAGGTAATAGCAAAATTCAGGAATACCGGGGTGAGTCCGGCCCTGGTGACGGAGGGATCCGGCAGAACACTGGTTC
TGGCGACAGCAAACGGCAAGGAATGGTTCTGCAATGATAATACCGATCCTGTCTCCGGGATTCCCGACCTTGTCCCGGGT
AATGTCCTGCCCCAGCACCGGCCGTCATCCTGCAAATAG

Upstream 100 bases:

>100_bases
GAAAGGAATATTGCTGGGTTCGGTTGCCAGCAAGGTCATACAGCTTTCGACAATACCGGTGCTCCTGATCAAATAGGATG
GCGGATATCAGGGAATAGTG

Downstream 100 bases:

>100_bases
GAGGAAGCGCGAAAAAGAGGATTTGCGGTCCACTTCGTCCGCCTCGACCACTGTGGGCGCTTCGGCACTCATCAGGGGTT
ACAAACCTGGTTCAATAATT

Product: N-terminal methylation site

Products: NA

Alternate protein names: L-pilin [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MRLTKKEFFSMKQDQKGLTLIESMMVVALIGILATIAIPPAFRLYEDSQARAQVTEALDLLGRVKSPVAAFYSDKGRWPT
SEEFDNLVPARTGKYVASLTPESREKGFEVIAKFRNTGVSPALVTEGSGRTLVLATANGKEWFCNDNTDPVSGIPDLVPG
NVLPQHRPSSCK

Sequences:

>Translated_172_residues
MRLTKKEFFSMKQDQKGLTLIESMMVVALIGILATIAIPPAFRLYEDSQARAQVTEALDLLGRVKSPVAAFYSDKGRWPT
SEEFDNLVPARTGKYVASLTPESREKGFEVIAKFRNTGVSPALVTEGSGRTLVLATANGKEWFCNDNTDPVSGIPDLVPG
NVLPQHRPSSCK
>Mature_172_residues
MRLTKKEFFSMKQDQKGLTLIESMMVVALIGILATIAIPPAFRLYEDSQARAQVTEALDLLGRVKSPVAAFYSDKGRWPT
SEEFDNLVPARTGKYVASLTPESREKGFEVIAKFRNTGVSPALVTEGSGRTLVLATANGKEWFCNDNTDPVSGIPDLVPG
NVLPQHRPSSCK

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 18816; Mature: 18816

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTKKEFFSMKQDQKGLTLIESMMVVALIGILATIAIPPAFRLYEDSQARAQVTEALDL
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHH
LGRVKSPVAAFYSDKGRWPTSEEFDNLVPARTGKYVASLTPESREKGFEVIAKFRNTGVS
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCC
PALVTEGSGRTLVLATANGKEWFCNDNTDPVSGIPDLVPGNVLPQHRPSSCK
CEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLTKKEFFSMKQDQKGLTLIESMMVVALIGILATIAIPPAFRLYEDSQARAQVTEALDL
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHH
LGRVKSPVAAFYSDKGRWPTSEEFDNLVPARTGKYVASLTPESREKGFEVIAKFRNTGVS
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCC
PALVTEGSGRTLVLATANGKEWFCNDNTDPVSGIPDLVPGNVLPQHRPSSCK
CEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906968 [H]