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The map label for this gene is ahpC [C]

Identifier: 82703502

GI number: 82703502

Start: 2719691

End: 2720293

Strand: Direct

Name: ahpC [C]

Synonym: Nmul_A2387

Alternate gene names: 82703502

Gene position: 2719691-2720293 (Clockwise)

Preceding gene: 82703501

Following gene: 82703503

Centisome position: 85.41

GC content: 54.73

Gene sequence:

>603_bases
ATGGCAGTGCTTGTTACACACCCTGCACCCGATTTCACAAAACCTGCTGTTCTGGCAGATGGCACCTTCAATGACAACTT
CAACTTTCATGCGCAAATTGCTGGTAAATATGCCGTATTGTTCTTTTATCCTCTGGATTTCACCTTTGTCTGTCCCTCCG
AAATCATTGCGCACTCGCATCGCATAGAGGAGTTTCGCAAGCGCAACGTGGAAGTGATTGGAGTCTCGGTGGATTCCCAG
TTCACCCACTACGCGTGGCGCAACACCCCTGTCGACAAAGGCGGCATTGGTCCGGTGGGAATCACGCTGGTATCCGACGT
AGGGGGAGACATCATGCACGCTTACGGCATTGCCCACCCGGACCACGTTGCCCTGCGCGCCTCTTTCCTGATAGATAAAA
ACACCATCGTGCGCCACGAAGTCGTTAACGACCTGCCCCTGGGGCGGGATGTAGACGAAATGCTGCGCATGGTCGATGCC
CTGCAATTTCACGAAAGCCATGGAGAGGTGTGCCCGGCCGGGTGGAAAGCAGGTGAACCCGGAATGAAAGCCAGTCCCGA
GGGTGTGGCGGAATATCTGGAAAGTCATGGCGAAGCGCTCTGA

Upstream 100 bases:

>100_bases
AGCAGAAGCAACAGCAGGAAGGTGGCATATCCAGGATGCAACGAAATGTGGCGGAAGATGTGGCAGTTTTCATGGTTCAT
GATGAATAAGGAGATTCAAG

Downstream 100 bases:

>100_bases
CGCAACGAACCTGCACCTCCTTGAACTCCTCTCCTGTAACCATAAGGGTGAAACACATGGATTTCGATAAAGACAAGGCG
ATCGCGCTGCTGAACCGAAT

Product: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MAVLVTHPAPDFTKPAVLADGTFNDNFNFHAQIAGKYAVLFFYPLDFTFVCPSEIIAHSHRIEEFRKRNVEVIGVSVDSQ
FTHYAWRNTPVDKGGIGPVGITLVSDVGGDIMHAYGIAHPDHVALRASFLIDKNTIVRHEVVNDLPLGRDVDEMLRMVDA
LQFHESHGEVCPAGWKAGEPGMKASPEGVAEYLESHGEAL

Sequences:

>Translated_200_residues
MAVLVTHPAPDFTKPAVLADGTFNDNFNFHAQIAGKYAVLFFYPLDFTFVCPSEIIAHSHRIEEFRKRNVEVIGVSVDSQ
FTHYAWRNTPVDKGGIGPVGITLVSDVGGDIMHAYGIAHPDHVALRASFLIDKNTIVRHEVVNDLPLGRDVDEMLRMVDA
LQFHESHGEVCPAGWKAGEPGMKASPEGVAEYLESHGEAL
>Mature_199_residues
AVLVTHPAPDFTKPAVLADGTFNDNFNFHAQIAGKYAVLFFYPLDFTFVCPSEIIAHSHRIEEFRKRNVEVIGVSVDSQF
THYAWRNTPVDKGGIGPVGITLVSDVGGDIMHAYGIAHPDHVALRASFLIDKNTIVRHEVVNDLPLGRDVDEMLRMVDAL
QFHESHGEVCPAGWKAGEPGMKASPEGVAEYLESHGEAL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=193, Percent_Identity=52.3316062176166, Blast_Score=204, Evalue=3e-53,
Organism=Homo sapiens, GI32455266, Length=193, Percent_Identity=52.3316062176166, Blast_Score=204, Evalue=3e-53,
Organism=Homo sapiens, GI32455264, Length=193, Percent_Identity=52.3316062176166, Blast_Score=204, Evalue=3e-53,
Organism=Homo sapiens, GI32189392, Length=193, Percent_Identity=52.3316062176166, Blast_Score=201, Evalue=3e-52,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=50, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI5802974, Length=191, Percent_Identity=49.738219895288, Blast_Score=183, Evalue=8e-47,
Organism=Homo sapiens, GI32483377, Length=187, Percent_Identity=49.7326203208556, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI33188454, Length=82, Percent_Identity=62.1951219512195, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI4758638, Length=189, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=9e-13,
Organism=Escherichia coli, GI1786822, Length=153, Percent_Identity=37.9084967320261, Blast_Score=108, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI32565831, Length=194, Percent_Identity=47.4226804123711, Blast_Score=177, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI193204376, Length=194, Percent_Identity=47.4226804123711, Blast_Score=177, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17554494, Length=197, Percent_Identity=43.1472081218274, Blast_Score=165, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI25153706, Length=178, Percent_Identity=27.5280898876405, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323613, Length=196, Percent_Identity=41.8367346938776, Blast_Score=158, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6320661, Length=196, Percent_Identity=37.7551020408163, Blast_Score=141, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6319407, Length=184, Percent_Identity=28.804347826087, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24656348, Length=191, Percent_Identity=49.2146596858639, Blast_Score=186, Evalue=7e-48,
Organism=Drosophila melanogaster, GI17864676, Length=191, Percent_Identity=49.2146596858639, Blast_Score=186, Evalue=7e-48,
Organism=Drosophila melanogaster, GI17157991, Length=192, Percent_Identity=48.9583333333333, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24641739, Length=192, Percent_Identity=48.9583333333333, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI17738015, Length=199, Percent_Identity=47.2361809045226, Blast_Score=177, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=43.979057591623, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24581278, Length=168, Percent_Identity=27.3809523809524, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17975518, Length=182, Percent_Identity=31.3186813186813, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24652434, Length=182, Percent_Identity=31.3186813186813, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24652436, Length=182, Percent_Identity=31.3186813186813, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21976; Mature: 21845

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVTHPAPDFTKPAVLADGTFNDNFNFHAQIAGKYAVLFFYPLDFTFVCPSEIIAHSH
CEEEEECCCCCCCCCEEEECCCCCCCCEEEEEECCCEEEEEEEECCEEEECHHHHHHHHH
RIEEFRKRNVEVIGVSVDSQFTHYAWRNTPVDKGGIGPVGITLVSDVGGDIMHAYGIAHP
HHHHHHHCCEEEEEEEECCCEEEHEECCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCC
DHVALRASFLIDKNTIVRHEVVNDLPLGRDVDEMLRMVDALQFHESHGEVCPAGWKAGEP
CHHEEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GMKASPEGVAEYLESHGEAL
CCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AVLVTHPAPDFTKPAVLADGTFNDNFNFHAQIAGKYAVLFFYPLDFTFVCPSEIIAHSH
EEEEECCCCCCCCCEEEECCCCCCCCEEEEEECCCEEEEEEEECCEEEECHHHHHHHHH
RIEEFRKRNVEVIGVSVDSQFTHYAWRNTPVDKGGIGPVGITLVSDVGGDIMHAYGIAHP
HHHHHHHCCEEEEEEEECCCEEEHEECCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCC
DHVALRASFLIDKNTIVRHEVVNDLPLGRDVDEMLRMVDALQFHESHGEVCPAGWKAGEP
CHHEEEEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GMKASPEGVAEYLESHGEAL
CCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]