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The map label for this gene is engA

Identifier: 82703488

GI number: 82703488

Start: 2698751

End: 2700151

Strand: Reverse

Name: engA

Synonym: Nmul_A2373

Alternate gene names: 82703488

Gene position: 2700151-2698751 (Counterclockwise)

Preceding gene: 82703489

Following gene: 82703486

Centisome position: 84.8

GC content: 57.46

Gene sequence:

>1401_bases
ATGAAACCCACCCTCGTACTGGTAGGGCGATCCAACGTCGGCAAGTCCACGCTCTTTAACCGTTTGACACGCAGCCGCGA
CGCGCTGGTGGCCGACCTGCCGGGGTTGACGCGCGACCGTCATTACGGACACGGCAAACTGGGTGACAGGCCGTATCTCG
TGGTCGATACAGGAGGCTTCGAGCCGATGGCAACGGAAGGCATCCTGCACGAAATGGCGAAGCAGACACTGCAAGCAATT
GACGAGGCTGATGTCGTGCTCTTTATCGTGGACGGTCGAAGCGGTTTGACGGCGCAGGACAAAATTGTCGCCGAGCAACT
GCGCAGATCGGGTCGCCGAACCTTGCTGGCGGTAAACAAGACCGAAGGCATGGCTGTTTCCGTCGTTACTGCGGAGTTTC
ACGAACTGGGATTGGGCGAGCCTTGCGCGATTTCCGCCGCCCATGGCGACAACGTGAATGAACTGGTGACACTGGCGCTT
CAGGATTTTCCCGACGAACCTGAGCAGGAAAGAAAAGACGACCATCCGAAAATCGCCATCGTGGGTCGTCCCAATGTAGG
AAAATCAACGCTCGTGAACACCCTGCTGGGAGAGGAGCGTGTCATCGCCTTTGATCAGCCGGGAACTACGCGTGACAGCA
TTTATATCGATTTTGAGCGGAATGGGCGCACTTATACCCTGATCGATACAGCGGGCCTGCGTCGACGCGGCAAGGTGCAG
GAGACCGTGGAGAAGTTTTCCGTGGTGAAAACACTGCAAGCGATAGAAGATGCCAACGTGGTGATACTGGTGCTGGATGC
AGCCAGTGAAATTTCAGATCAGGATGCGCATATTGGCGGATTCATCCTGGAAGCAGGACGGGCACTGGTGCTGGCCGTGA
ACAAGTGGGACAGCCTGGATGAGTACCAGCGTGACATGATCAAGCGCGATATCAACCGTAAATTGCCGTTTCTGCAGAAT
TTCGCCCGGTTTCACTATATTTCGGCGCTACATGGCACTGGCACGAAAGGGTTGCTGCCCTCTGTCGATGCCGCCTATGG
GGCGGCGATGGCTCATCTGCCTACTCCCAGGCTTACGCGCACATTATTGGCCGCGGTGGAGAAGCAGCCTCCCCCGCGTG
CCGGCATGTCGCGTCCCAAGCTGCGCTACGCCCATCAGGGCGGTTCGAATCCGCCCCTGATTATAATCCATGGCAGCGCT
CTCAATGCCGTGCCCCAGACCTATCAGCGCTATCTGGAAAATACATTTCGCGATACCTTCGGGCTGGAGGGAACGCCGCT
CCGGATAGAATTCAGGACAGGCCGCAATCCCTACGCAGGGAAAAGCCCCGCTCCGCTCACCGAAGCCGAGGCAAAACGGG
CTCATCGTCGTCGACGATACGGGCGGAAGAAGTATGGGTAA

Upstream 100 bases:

>100_bases
TTCTGGGGAATACCTCGGTAATCCGGGAATTCGCTGTCCAGCGCTTCAATTCCGTACCTTATGCCGCAGCCCAGCCCTGT
TTTAGACGAAAGCTGAAATC

Downstream 100 bases:

>100_bases
CGCCGAGGGGAAGATACTTCTTAATGGAGGATTCGCGGCACGCTCAGAATGAACTCGGGAATGGGGGCGTCGAAGCGCAG
ACCATCCTCGGCCACCATCT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKPTLVLVGRSNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGHGKLGDRPYLVVDTGGFEPMATEGILHEMAKQTLQAI
DEADVVLFIVDGRSGLTAQDKIVAEQLRRSGRRTLLAVNKTEGMAVSVVTAEFHELGLGEPCAISAAHGDNVNELVTLAL
QDFPDEPEQERKDDHPKIAIVGRPNVGKSTLVNTLLGEERVIAFDQPGTTRDSIYIDFERNGRTYTLIDTAGLRRRGKVQ
ETVEKFSVVKTLQAIEDANVVILVLDAASEISDQDAHIGGFILEAGRALVLAVNKWDSLDEYQRDMIKRDINRKLPFLQN
FARFHYISALHGTGTKGLLPSVDAAYGAAMAHLPTPRLTRTLLAAVEKQPPPRAGMSRPKLRYAHQGGSNPPLIIIHGSA
LNAVPQTYQRYLENTFRDTFGLEGTPLRIEFRTGRNPYAGKSPAPLTEAEAKRAHRRRRYGRKKYG

Sequences:

>Translated_466_residues
MKPTLVLVGRSNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGHGKLGDRPYLVVDTGGFEPMATEGILHEMAKQTLQAI
DEADVVLFIVDGRSGLTAQDKIVAEQLRRSGRRTLLAVNKTEGMAVSVVTAEFHELGLGEPCAISAAHGDNVNELVTLAL
QDFPDEPEQERKDDHPKIAIVGRPNVGKSTLVNTLLGEERVIAFDQPGTTRDSIYIDFERNGRTYTLIDTAGLRRRGKVQ
ETVEKFSVVKTLQAIEDANVVILVLDAASEISDQDAHIGGFILEAGRALVLAVNKWDSLDEYQRDMIKRDINRKLPFLQN
FARFHYISALHGTGTKGLLPSVDAAYGAAMAHLPTPRLTRTLLAAVEKQPPPRAGMSRPKLRYAHQGGSNPPLIIIHGSA
LNAVPQTYQRYLENTFRDTFGLEGTPLRIEFRTGRNPYAGKSPAPLTEAEAKRAHRRRRYGRKKYG
>Mature_466_residues
MKPTLVLVGRSNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGHGKLGDRPYLVVDTGGFEPMATEGILHEMAKQTLQAI
DEADVVLFIVDGRSGLTAQDKIVAEQLRRSGRRTLLAVNKTEGMAVSVVTAEFHELGLGEPCAISAAHGDNVNELVTLAL
QDFPDEPEQERKDDHPKIAIVGRPNVGKSTLVNTLLGEERVIAFDQPGTTRDSIYIDFERNGRTYTLIDTAGLRRRGKVQ
ETVEKFSVVKTLQAIEDANVVILVLDAASEISDQDAHIGGFILEAGRALVLAVNKWDSLDEYQRDMIKRDINRKLPFLQN
FARFHYISALHGTGTKGLLPSVDAAYGAAMAHLPTPRLTRTLLAAVEKQPPPRAGMSRPKLRYAHQGGSNPPLIIIHGSA
LNAVPQTYQRYLENTFRDTFGLEGTPLRIEFRTGRNPYAGKSPAPLTEAEAKRAHRRRRYGRKKYG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=491, Percent_Identity=48.4725050916497, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=39.7849462365591, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788919, Length=186, Percent_Identity=32.258064516129, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_NITMU (Q2Y6F9)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413054.1
- HSSP:   O57939
- ProteinModelPortal:   Q2Y6F9
- SMR:   Q2Y6F9
- STRING:   Q2Y6F9
- GeneID:   3784964
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2373
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q2Y6F9
- ProtClustDB:   PRK00093
- BioCyc:   NMUL323848:NMUL_A2373-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 51478; Mature: 51478

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTLVLVGRSNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGHGKLGDRPYLVVDTGGF
CCCCEEEEECCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPMATEGILHEMAKQTLQAIDEADVVLFIVDGRSGLTAQDKIVAEQLRRSGRRTLLAVNK
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEC
TEGMAVSVVTAEFHELGLGEPCAISAAHGDNVNELVTLALQDFPDEPEQERKDDHPKIAI
CCCCEEEEEEHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEEE
VGRPNVGKSTLVNTLLGEERVIAFDQPGTTRDSIYIDFERNGRTYTLIDTAGLRRRGKVQ
EECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHH
ETVEKFSVVKTLQAIEDANVVILVLDAASEISDQDAHIGGFILEAGRALVLAVNKWDSLD
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHEECCCEEEEEECCCCCHH
EYQRDMIKRDINRKLPFLQNFARFHYISALHGTGTKGLLPSVDAAYGAAMAHLPTPRLTR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
TLLAAVEKQPPPRAGMSRPKLRYAHQGGSNPPLIIIHGSALNAVPQTYQRYLENTFRDTF
HHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHC
GLEGTPLRIEFRTGRNPYAGKSPAPLTEAEAKRAHRRRRYGRKKYG
CCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKPTLVLVGRSNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGHGKLGDRPYLVVDTGGF
CCCCEEEEECCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPMATEGILHEMAKQTLQAIDEADVVLFIVDGRSGLTAQDKIVAEQLRRSGRRTLLAVNK
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEC
TEGMAVSVVTAEFHELGLGEPCAISAAHGDNVNELVTLALQDFPDEPEQERKDDHPKIAI
CCCCEEEEEEHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHCCCCCEEEE
VGRPNVGKSTLVNTLLGEERVIAFDQPGTTRDSIYIDFERNGRTYTLIDTAGLRRRGKVQ
EECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCHH
ETVEKFSVVKTLQAIEDANVVILVLDAASEISDQDAHIGGFILEAGRALVLAVNKWDSLD
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHEECCCEEEEEECCCCCHH
EYQRDMIKRDINRKLPFLQNFARFHYISALHGTGTKGLLPSVDAAYGAAMAHLPTPRLTR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
TLLAAVEKQPPPRAGMSRPKLRYAHQGGSNPPLIIIHGSALNAVPQTYQRYLENTFRDTF
HHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHC
GLEGTPLRIEFRTGRNPYAGKSPAPLTEAEAKRAHRRRRYGRKKYG
CCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA