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The map label for this gene is fabG [H]

Identifier: 82703425

GI number: 82703425

Start: 2625978

End: 2626349

Strand: Direct

Name: fabG [H]

Synonym: Nmul_A2308

Alternate gene names: 82703425

Gene position: 2625978-2626349 (Clockwise)

Preceding gene: 82703422

Following gene: 82703426

Centisome position: 82.47

GC content: 59.95

Gene sequence:

>372_bases
ATGAACACAAAACGGCGCGCGATCAGCAAGGATACGTTCGGTCTTTCCGGGCAGATTGCCGTGCTGACCGGAGTGTCTTC
AGGCATAGGCCGCGCTTGCGCCCTTGCCTTGGGGCGCGTGGGCGTGAAGGTGGTAGTCAATCCCCTTCCTGAGGCCAGCG
ACGAGGCAGCCGAGGTGTGCCGAGAAATAGAAGCCGTCGGCGTGGACGCTTTTGCCTATGCCGCCGATGTGAGTAACGAA
ACTCAGCTCGCGGCTATGTTCACGGAAACGGTGGCACGCTTCGGCACTCTCCATATTCTGGTGAACAACGCCGGAATAAT
GTTCGCCGATGGCGCAATGTCGACCTATCCCGCGTTCCGTCGCGCGGGATGA

Upstream 100 bases:

>100_bases
TCAAGCGGGAAGCGACGGAAGCATGTCAAGGCAGACGTTTTGTACCCGTTCAATTCTTCGATCAGCAGGGTAGCTATTGA
GGATCAGGGAAAAGAATCCA

Downstream 100 bases:

>100_bases
GCAAACCTATCGAAGAATACGGATTCATCGGTAACATGCTGAGCGGAGCGCTCGTCGCCCGTGATGGCTCGATGGATTGG
CTTTGCCTTCCACGGTTCGA

Product: Short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MNTKRRAISKDTFGLSGQIAVLTGVSSGIGRACALALGRVGVKVVVNPLPEASDEAAEVCREIEAVGVDAFAYAADVSNE
TQLAAMFTETVARFGTLHILVNNAGIMFADGAMSTYPAFRRAG

Sequences:

>Translated_123_residues
MNTKRRAISKDTFGLSGQIAVLTGVSSGIGRACALALGRVGVKVVVNPLPEASDEAAEVCREIEAVGVDAFAYAADVSNE
TQLAAMFTETVARFGTLHILVNNAGIMFADGAMSTYPAFRRAG
>Mature_123_residues
MNTKRRAISKDTFGLSGQIAVLTGVSSGIGRACALALGRVGVKVVVNPLPEASDEAAEVCREIEAVGVDAFAYAADVSNE
TQLAAMFTETVARFGTLHILVNNAGIMFADGAMSTYPAFRRAG

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1787905, Length=97, Percent_Identity=36.0824742268041, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI2367175, Length=102, Percent_Identity=43.1372549019608, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI87082160, Length=101, Percent_Identity=35.6435643564356, Blast_Score=59, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI193203117, Length=93, Percent_Identity=36.5591397849462, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 12796; Mature: 12796

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKRRAISKDTFGLSGQIAVLTGVSSGIGRACALALGRVGVKVVVNPLPEASDEAAEVC
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHH
REIEAVGVDAFAYAADVSNETQLAAMFTETVARFGTLHILVNNAGIMFADGAMSTYPAFR
HHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCEEEEEEECCCEEEECCCCCCCCHHH
RAG
CCC
>Mature Secondary Structure
MNTKRRAISKDTFGLSGQIAVLTGVSSGIGRACALALGRVGVKVVVNPLPEASDEAAEVC
CCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHH
REIEAVGVDAFAYAADVSNETQLAAMFTETVARFGTLHILVNNAGIMFADGAMSTYPAFR
HHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCEEEEEEECCCEEEECCCCCCCCHHH
RAG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA