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The map label for this gene is grsT [H]

Identifier: 82702957

GI number: 82702957

Start: 2116514

End: 2117275

Strand: Reverse

Name: grsT [H]

Synonym: Nmul_A1834

Alternate gene names: 82702957

Gene position: 2117275-2116514 (Counterclockwise)

Preceding gene: 82702958

Following gene: 82702956

Centisome position: 66.49

GC content: 57.74

Gene sequence:

>762_bases
ATGTCCCCGATCCTGACACTTTTCGCGCTGCCATGCGCAGGCGCGAGCTCGGTCATGTATCTGCGCTGGCGGCGCAGATT
GCCTTCCTGGGTGCAAGTGGAACCGGTCGAGCTGCCGGGTCGTGGAGGCCGCCTGGATGAAATGTTCGCGAAAAGCTTCC
CTTCACTGGTCGAGCGCCTAACGGATGAGATCGAGGCGTGCCCGCCCCGTCGATACGCATTCTTCGGGCACAGCATGGGA
GCGCTGCTCGCTTTCGGAATTGCCCATTCCTTGCGCAAGAGAGAAAGACCCTTGCCTCTTGCCCTGTTTGTGTCGGGCTG
TGCCGCACCCTCCCGGCAGGACTGGCGGCGTTATGCGGACAAGAATGCCGACGCGTCGCTCATTGCTGATCTGCGCAAGC
AGAAAGGGACACCGGAAGAGGTGTTCGAGAGCCCGGAGTTGTTGTCCCTGACGCTCAGCCTGCTGCGTGCGGACTACCGC
ATCTGCGCGAGCTTTCGCCACACGCAATCCTTGCCTTTGCCGCTGCCGATTCATGTTTTTGGGGGCCGGGGCGATGAAAT
TCATGAGTCGAAACTGGAAGCATGGCAATCCGAAACTACAGAAGAGTTGTCACTGGATCTGTTTGAAGGAGGGCATTTCT
TTCTCCGTCAGCACGAAGAGGCCTTTCTTCCCGTGCTCGTCCAGAGAATGGCTCTATACCGTCCAGAGGTATATCAGGAA
GCACATCGAGAACCTGCTGATATGTCCCTATGTATTCCATAA

Upstream 100 bases:

>100_bases
AGAAAACCTGCCTGGAACATGTAGAGAAAGTCTGGACGGATATGCGCCCCCTCAGCCTGCGGCGCTTCATGGACGAACAA
TGTCCCGCTGAAGCCAGGTG

Downstream 100 bases:

>100_bases
GGTATCCACTAAGGTCTCCCATAAGGCGCTTGCCGCTGTCCGAGCGCATTCCGGATGGCATGGAAGTGTGGTTGCTCGAG
CTTGATGTTGGGCTCTCGGT

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSPILTLFALPCAGASSVMYLRWRRRLPSWVQVEPVELPGRGGRLDEMFAKSFPSLVERLTDEIEACPPRRYAFFGHSMG
ALLAFGIAHSLRKRERPLPLALFVSGCAAPSRQDWRRYADKNADASLIADLRKQKGTPEEVFESPELLSLTLSLLRADYR
ICASFRHTQSLPLPLPIHVFGGRGDEIHESKLEAWQSETTEELSLDLFEGGHFFLRQHEEAFLPVLVQRMALYRPEVYQE
AHREPADMSLCIP

Sequences:

>Translated_253_residues
MSPILTLFALPCAGASSVMYLRWRRRLPSWVQVEPVELPGRGGRLDEMFAKSFPSLVERLTDEIEACPPRRYAFFGHSMG
ALLAFGIAHSLRKRERPLPLALFVSGCAAPSRQDWRRYADKNADASLIADLRKQKGTPEEVFESPELLSLTLSLLRADYR
ICASFRHTQSLPLPLPIHVFGGRGDEIHESKLEAWQSETTEELSLDLFEGGHFFLRQHEEAFLPVLVQRMALYRPEVYQE
AHREPADMSLCIP
>Mature_252_residues
SPILTLFALPCAGASSVMYLRWRRRLPSWVQVEPVELPGRGGRLDEMFAKSFPSLVERLTDEIEACPPRRYAFFGHSMGA
LLAFGIAHSLRKRERPLPLALFVSGCAAPSRQDWRRYADKNADASLIADLRKQKGTPEEVFESPELLSLTLSLLRADYRI
CASFRHTQSLPLPLPIHVFGGRGDEIHESKLEAWQSETTEELSLDLFEGGHFFLRQHEEAFLPVLVQRMALYRPEVYQEA
HREPADMSLCIP

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=214, Percent_Identity=27.1028037383178, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI8922871, Length=222, Percent_Identity=28.3783783783784, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 28761; Mature: 28630

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPILTLFALPCAGASSVMYLRWRRRLPSWVQVEPVELPGRGGRLDEMFAKSFPSLVERL
CCHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECEECCCCCCCHHHHHHHHHHHHHHHH
TDEIEACPPRRYAFFGHSMGALLAFGIAHSLRKRERPLPLALFVSGCAAPSRQDWRRYAD
HHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHC
KNADASLIADLRKQKGTPEEVFESPELLSLTLSLLRADYRICASFRHTQSLPLPLPIHVF
CCCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
GGRGDEIHESKLEAWQSETTEELSLDLFEGGHFFLRQHEEAFLPVLVQRMALYRPEVYQE
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AHREPADMSLCIP
HCCCCCCCEECCC
>Mature Secondary Structure 
SPILTLFALPCAGASSVMYLRWRRRLPSWVQVEPVELPGRGGRLDEMFAKSFPSLVERL
CHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECEECCCCCCCHHHHHHHHHHHHHHHH
TDEIEACPPRRYAFFGHSMGALLAFGIAHSLRKRERPLPLALFVSGCAAPSRQDWRRYAD
HHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHC
KNADASLIADLRKQKGTPEEVFESPELLSLTLSLLRADYRICASFRHTQSLPLPLPIHVF
CCCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
GGRGDEIHESKLEAWQSETTEELSLDLFEGGHFFLRQHEEAFLPVLVQRMALYRPEVYQE
CCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AHREPADMSLCIP
HCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]