Click here to switch to the map view.

The map label for this gene is lgrB [H]

Identifier: 82702953

GI number: 82702953

Start: 2102035

End: 2105451

Strand: Reverse

Name: lgrB [H]

Synonym: Nmul_A1830

Alternate gene names: 82702953

Gene position: 2105451-2102035 (Counterclockwise)

Preceding gene: 82702954

Following gene: 82702952

Centisome position: 66.12

GC content: 59.5

Gene sequence:

>3417_bases
ATGCATAGCAGCAGTCTAGTTCAAAGACGCGCCCGCCTGACCCCCGAGCAACGGGAGAGGCTGGCGCAGCGGCTGGCCGG
AGCTCATGCTCCAGCACTTCAATCGAATATCCCTTGCCGCAATGCTTCCGCGCGGGTGCCGCTCTCATACGCACAGGAGC
GTCACTGGTTTTTATGGCAATTGGAGCCGTTGAGCACGGCTTATCATTTGAGCGGGGGATTGCGGCTGACGGGCAGGGTG
GATATTGAAGCGCTGCGTTGGAGCTTTGCGGCGCTGGGCAGGCGGCATGAGTCGTTGCGTACGATATTCAGGGTCAATTC
GGAAGGGTTGCCGGAGCAGATCATCGAAGACGAGCCGCGGCTTGAAATTCCGCTGACCGACTTTTCCGGACTGCCGCTGG
AACAAGCCAGAGCGCAAGCCGGTGAAGAAGCGGGCCGGATAGCCGGCACGCCCTTTGATCTGACGCAAGGCCCGCTGCTT
CGGGTTGCCCTCATCCGCATTGCAGCGGAAGAACATCTTCTCGTGGTGGTGATGCACCACATCATCTCGGACGCCTGGTC
CAACCGCATTGTCATTGACGAATTTGCCGCCCACTATCGGGCACGGGTGCAGCAGGAGCAGGAGGGGGAGAAACAGGGGC
AGGAACCCTCCCTGCCGGCCCTGCCGATCCAGTATGCCGATTACGCGATATGGCAGCGCAACTGGCTGGAAGCGGGAGAA
AAAGAGCGCCAGCTGGCCTACTGGCGCAGCCAGTTGGGGGAAGAGCACCCGGTATTGCAATTGCCCACCGATCACCCCCG
ATCTTCCAGGGCCAGTTACCGTGCGGCGCGCCACACCTTCACATTACCTGCGGGTCTGGTTACACGCTTGCAGCGTCAGG
CGCAAAGCCAGGGAGCGACCCTGTTCATGGCGCTGCTCTCGGGCTTTCAAGGCCTGCTCTATCGCTATACCGGCCAGCGG
GATATCCGCGTGGGCGTGCCGATTGCCAACCGGCATCGGGCTGAAATAGAAAACATCGTCGGCTTCTTCGTCAATACCCA
GGTATTGCGCACCCTCATGGATGGGCGCATGTCCCTGCATACGTTGCTCGATCAGACGCGGGAAGCAGCGCTGGGTGCCC
AGACCCACCAGGATTTGCCGTTCGAGCGACTGGTTGAAGCCCTGCAACCCGAACGCAACCTGAATCAGAATCCTCTGTTT
CAGGTCATGTACAACCACCTGCGCGAAGACTACCGGGCACTCGAGCAATTGCCCGGGCTCAAGGTGGAAAATCACGAGCT
GAGCGAGCAGGCGGCGCAGTTCGAACTGACCCTGGATACGGTCGAGCAGCCCGATGGCAGGCTGGAAGCCACCTTCACCT
ATGCCGCCGAGCTGTTTGAACCTGCCACCATTGGGCGGCTTGGCAACCATTATCTGCTTCTTCTGGAGCAACTGGCCGAG
CATCCGCAGCAGAACCTTGGCGACATCGACATCCTCAGTGAAGCCGAGCGGGCGCAGCTCAAGGCCTGGGGGATCAACGA
GCAGCGCTACGCCAATACCGAGCCCGTGCACAGGCTGATCGAGCGGCAGGTTGAAGTCCAGCCGGAAGCGATTGCCCTGA
TCTTTGGCGATGTCGAATTGAGCTACGGCGAGCTGAACCGAAGGGCGAACCGCCTGGCGCACCGTTTGATCAGGCTTGGG
GTTGGGCCGGAGGTCAAGGTGGGCATTGCGGTGGAGCGCTCGATCGACATGGTGGTGGGGTTGCTTGCCACCCTGAAGGC
GGGCGGAGCATATGTGCCGCTTGATCCGGAATATCCGCAGGAGCGGCTGGCCTACATGGTGGCAGACAGTGGCATCGGGC
TGTTGCTGACGCAAAGCCGGGTTCGATCCGCCATTCCCCATTCCGACCAATGCGTGGTACTGGAGCTGGACAGGCTCGAT
CTCGAGGAGGAATCCGGCAGCAACCCGCAAGTCGCCCTGCATGGATACAACCTTGCCTACATCATCTATACCTCAGGCTC
CACAGGTAAACCAAAGGGCGTAAGTGTAGCGCATCATGCGCTGGTTGAGCATGCACAGGTAGCGGTAGGCTTCTTCGGTC
TTGGTTCCACAGACCGGATGTTGCAATTTTCCACCATCAACTTCGATGGGTTTATCGAACAGCTTTTCCCCCCCTTGTGC
GCGGGAGCCGCCGTTGTCTTGCGCGGCCCGGCGCTGTGGGACAGCGAGACTTTCTATCGCGAGCTGATCGAAAAGCGCAT
CACGGTTGCCGATCTTACCACCGCCTACTGGTTCATGCTGGTGCAGGATTTTGCCAGAGGGGGTCCACGCGACTACGGGT
TGTTACGCCAGGTTCATGCGGGCGGTGAGGCCATGTCGCCTGAAGGACTCAAAGCCTGGAGCGAGGCGGGATTCGACGGT
GTGACCCTGCTGAATACCTACGGTCCGACCGAAGCCGCTGTGACCGCGACCGTATGGAATTGCAGCGATTATTCGCAGGG
TAACGAAATATCCTCCCAAGTGTCCATTGTCCCTATTGTGTCGATTGGCAGTCCGCTTGCCGCCCGTCATATCTATCTGC
TGGACGCCAACCTGACTCCTGTTTCCCCTGGAATTCCCGGTGAGCTGTGCATAGGAGGGGAATTGCTCGCTCGCGGCTAT
CTCAACCGTGGAGGATTGACGGCGGAGCGTTTCATAGCCGATCCCTTCGATGGAGGAGGCGGACGACTCTACCGCACGGG
AGATCTGGCAAGATGGCGCTCGGACGGGCAGATCGAATATCTGGGGCGGCTGGATCATCAGGTCAAGATACGGGGATTCC
GCATCGAGCTGGGCGAAATCGAAATGCAACTGCTGGCGCAACCGGAAGTCAGGGAAGCGGTGGTGGTTGCCAGGGAAAGT
GCCCGCGGCTCCAATCCTGCGGGAGGAGCAAGACTCGTTGCCTATGTTTCCTTGCATGCGGAAGCGGAGATGGAAGTTGG
GCGACTGCGTGAAGCGTTGGGCAAGGTTTTGCCAGACTACATGCTGCCCTCAATGATTGTGGTGCTGGAGAGTCTGCCGC
TCAATCCGAGCGGCAAGGTAGACCGCAAGGCCTTGCCCGAGCCGGAGTTTACCCATACGGAGCATTATGAGGCGCCGCGG
GGGGAAGCGGAAGAGGTGCTGGCAGGTATCTGGGCGCAGGTGCTGGGTGTGGCGCAGGTGGGACGGCATGACAACTTCTT
TGAACTGGGGGGACATTCGCTCGCTATCCTCCAGGTTCAGCAGAAACTGCAACAAGCCCTATCCATTTCGTTGCCTTTGC
GGCTGCATTTCGAGAATCCCCTGCTGAAGGATATTGCTTCTGCCATCCAGGAAAAACGGTCCCGGGCATCCGAAAAAGAC
GCGGAGCAGGAGGACCTGTTGGGAATGGCGGAATTGCTTGATTTACTGGAGAGTTGA

Upstream 100 bases:

>100_bases
AACGAAATTACTGGACGAGATCGAGTGCCTATGATTTCCCGCCCCTTTGATGTGAAGCCATTCCATCTCCCGATGTTCCA
TCATTTTTATCCGCACCATC

Downstream 100 bases:

>100_bases
ATGGAATTGAACAAGCAGGATATTGCCGAGCGGTTCGCAGCCCTTGCTCCCGAGAAACAGAAAGAATTCCTGAATGCCCT
GAAAAAACGGGGATTCGATT

Product: amino acid adenylation

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1138; Mature: 1138

Protein sequence:

>1138_residues
MHSSSLVQRRARLTPEQRERLAQRLAGAHAPALQSNIPCRNASARVPLSYAQERHWFLWQLEPLSTAYHLSGGLRLTGRV
DIEALRWSFAALGRRHESLRTIFRVNSEGLPEQIIEDEPRLEIPLTDFSGLPLEQARAQAGEEAGRIAGTPFDLTQGPLL
RVALIRIAAEEHLLVVVMHHIISDAWSNRIVIDEFAAHYRARVQQEQEGEKQGQEPSLPALPIQYADYAIWQRNWLEAGE
KERQLAYWRSQLGEEHPVLQLPTDHPRSSRASYRAARHTFTLPAGLVTRLQRQAQSQGATLFMALLSGFQGLLYRYTGQR
DIRVGVPIANRHRAEIENIVGFFVNTQVLRTLMDGRMSLHTLLDQTREAALGAQTHQDLPFERLVEALQPERNLNQNPLF
QVMYNHLREDYRALEQLPGLKVENHELSEQAAQFELTLDTVEQPDGRLEATFTYAAELFEPATIGRLGNHYLLLLEQLAE
HPQQNLGDIDILSEAERAQLKAWGINEQRYANTEPVHRLIERQVEVQPEAIALIFGDVELSYGELNRRANRLAHRLIRLG
VGPEVKVGIAVERSIDMVVGLLATLKAGGAYVPLDPEYPQERLAYMVADSGIGLLLTQSRVRSAIPHSDQCVVLELDRLD
LEEESGSNPQVALHGYNLAYIIYTSGSTGKPKGVSVAHHALVEHAQVAVGFFGLGSTDRMLQFSTINFDGFIEQLFPPLC
AGAAVVLRGPALWDSETFYRELIEKRITVADLTTAYWFMLVQDFARGGPRDYGLLRQVHAGGEAMSPEGLKAWSEAGFDG
VTLLNTYGPTEAAVTATVWNCSDYSQGNEISSQVSIVPIVSIGSPLAARHIYLLDANLTPVSPGIPGELCIGGELLARGY
LNRGGLTAERFIADPFDGGGGRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIEMQLLAQPEVREAVVVARES
ARGSNPAGGARLVAYVSLHAEAEMEVGRLREALGKVLPDYMLPSMIVVLESLPLNPSGKVDRKALPEPEFTHTEHYEAPR
GEAEEVLAGIWAQVLGVAQVGRHDNFFELGGHSLAILQVQQKLQQALSISLPLRLHFENPLLKDIASAIQEKRSRASEKD
AEQEDLLGMAELLDLLES

Sequences:

>Translated_1138_residues
MHSSSLVQRRARLTPEQRERLAQRLAGAHAPALQSNIPCRNASARVPLSYAQERHWFLWQLEPLSTAYHLSGGLRLTGRV
DIEALRWSFAALGRRHESLRTIFRVNSEGLPEQIIEDEPRLEIPLTDFSGLPLEQARAQAGEEAGRIAGTPFDLTQGPLL
RVALIRIAAEEHLLVVVMHHIISDAWSNRIVIDEFAAHYRARVQQEQEGEKQGQEPSLPALPIQYADYAIWQRNWLEAGE
KERQLAYWRSQLGEEHPVLQLPTDHPRSSRASYRAARHTFTLPAGLVTRLQRQAQSQGATLFMALLSGFQGLLYRYTGQR
DIRVGVPIANRHRAEIENIVGFFVNTQVLRTLMDGRMSLHTLLDQTREAALGAQTHQDLPFERLVEALQPERNLNQNPLF
QVMYNHLREDYRALEQLPGLKVENHELSEQAAQFELTLDTVEQPDGRLEATFTYAAELFEPATIGRLGNHYLLLLEQLAE
HPQQNLGDIDILSEAERAQLKAWGINEQRYANTEPVHRLIERQVEVQPEAIALIFGDVELSYGELNRRANRLAHRLIRLG
VGPEVKVGIAVERSIDMVVGLLATLKAGGAYVPLDPEYPQERLAYMVADSGIGLLLTQSRVRSAIPHSDQCVVLELDRLD
LEEESGSNPQVALHGYNLAYIIYTSGSTGKPKGVSVAHHALVEHAQVAVGFFGLGSTDRMLQFSTINFDGFIEQLFPPLC
AGAAVVLRGPALWDSETFYRELIEKRITVADLTTAYWFMLVQDFARGGPRDYGLLRQVHAGGEAMSPEGLKAWSEAGFDG
VTLLNTYGPTEAAVTATVWNCSDYSQGNEISSQVSIVPIVSIGSPLAARHIYLLDANLTPVSPGIPGELCIGGELLARGY
LNRGGLTAERFIADPFDGGGGRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIEMQLLAQPEVREAVVVARES
ARGSNPAGGARLVAYVSLHAEAEMEVGRLREALGKVLPDYMLPSMIVVLESLPLNPSGKVDRKALPEPEFTHTEHYEAPR
GEAEEVLAGIWAQVLGVAQVGRHDNFFELGGHSLAILQVQQKLQQALSISLPLRLHFENPLLKDIASAIQEKRSRASEKD
AEQEDLLGMAELLDLLES
>Mature_1138_residues
MHSSSLVQRRARLTPEQRERLAQRLAGAHAPALQSNIPCRNASARVPLSYAQERHWFLWQLEPLSTAYHLSGGLRLTGRV
DIEALRWSFAALGRRHESLRTIFRVNSEGLPEQIIEDEPRLEIPLTDFSGLPLEQARAQAGEEAGRIAGTPFDLTQGPLL
RVALIRIAAEEHLLVVVMHHIISDAWSNRIVIDEFAAHYRARVQQEQEGEKQGQEPSLPALPIQYADYAIWQRNWLEAGE
KERQLAYWRSQLGEEHPVLQLPTDHPRSSRASYRAARHTFTLPAGLVTRLQRQAQSQGATLFMALLSGFQGLLYRYTGQR
DIRVGVPIANRHRAEIENIVGFFVNTQVLRTLMDGRMSLHTLLDQTREAALGAQTHQDLPFERLVEALQPERNLNQNPLF
QVMYNHLREDYRALEQLPGLKVENHELSEQAAQFELTLDTVEQPDGRLEATFTYAAELFEPATIGRLGNHYLLLLEQLAE
HPQQNLGDIDILSEAERAQLKAWGINEQRYANTEPVHRLIERQVEVQPEAIALIFGDVELSYGELNRRANRLAHRLIRLG
VGPEVKVGIAVERSIDMVVGLLATLKAGGAYVPLDPEYPQERLAYMVADSGIGLLLTQSRVRSAIPHSDQCVVLELDRLD
LEEESGSNPQVALHGYNLAYIIYTSGSTGKPKGVSVAHHALVEHAQVAVGFFGLGSTDRMLQFSTINFDGFIEQLFPPLC
AGAAVVLRGPALWDSETFYRELIEKRITVADLTTAYWFMLVQDFARGGPRDYGLLRQVHAGGEAMSPEGLKAWSEAGFDG
VTLLNTYGPTEAAVTATVWNCSDYSQGNEISSQVSIVPIVSIGSPLAARHIYLLDANLTPVSPGIPGELCIGGELLARGY
LNRGGLTAERFIADPFDGGGGRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIEMQLLAQPEVREAVVVARES
ARGSNPAGGARLVAYVSLHAEAEMEVGRLREALGKVLPDYMLPSMIVVLESLPLNPSGKVDRKALPEPEFTHTEHYEAPR
GEAEEVLAGIWAQVLGVAQVGRHDNFFELGGHSLAILQVQQKLQQALSISLPLRLHFENPLLKDIASAIQEKRSRASEKD
AEQEDLLGMAELLDLLES

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI187761345, Length=544, Percent_Identity=26.2867647058824, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI187761343, Length=544, Percent_Identity=26.2867647058824, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI45580730, Length=584, Percent_Identity=22.4315068493151, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI42544132, Length=513, Percent_Identity=23.0019493177388, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI28416953, Length=556, Percent_Identity=24.6402877697842, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI38505220, Length=531, Percent_Identity=22.9755178907721, Blast_Score=85, Evalue=4e-16,
Organism=Homo sapiens, GI157311624, Length=450, Percent_Identity=23.1111111111111, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI157311622, Length=450, Percent_Identity=23.1111111111111, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI58082049, Length=447, Percent_Identity=22.3713646532438, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI122937307, Length=383, Percent_Identity=26.3707571801567, Blast_Score=80, Evalue=8e-15,
Organism=Escherichia coli, GI1786801, Length=1069, Percent_Identity=29.8409728718428, Blast_Score=321, Evalue=2e-88,
Organism=Escherichia coli, GI145693145, Length=529, Percent_Identity=24.3856332703214, Blast_Score=101, Evalue=3e-22,
Organism=Escherichia coli, GI1786810, Length=546, Percent_Identity=25.0915750915751, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1788107, Length=576, Percent_Identity=23.7847222222222, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI221142682, Length=512, Percent_Identity=23.4375, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17550940, Length=1075, Percent_Identity=22.3255813953488, Blast_Score=154, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17556356, Length=592, Percent_Identity=24.8310810810811, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32563687, Length=526, Percent_Identity=22.8136882129278, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560140, Length=383, Percent_Identity=25.3263707571802, Blast_Score=77, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=974, Percent_Identity=24.6406570841889, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6319699, Length=505, Percent_Identity=20.990099009901, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648676, Length=614, Percent_Identity=30.6188925081433, Blast_Score=200, Evalue=6e-51,
Organism=Drosophila melanogaster, GI24581924, Length=577, Percent_Identity=24.263431542461, Blast_Score=93, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 126573; Mature: 126573

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSSSLVQRRARLTPEQRERLAQRLAGAHAPALQSNIPCRNASARVPLSYAQERHWFLWQ
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCHHHHCCCCEEEEE
LEPLSTAYHLSGGLRLTGRVDIEALRWSFAALGRRHESLRTIFRVNSEGLPEQIIEDEPR
ECCCCEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCC
LEIPLTDFSGLPLEQARAQAGEEAGRIAGTPFDLTQGPLLRVALIRIAAEEHLLVVVMHH
EEEECCCCCCCCHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
IISDAWSNRIVIDEFAAHYRARVQQEQEGEKQGQEPSLPALPIQYADYAIWQRNWLEAGE
HHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
KERQLAYWRSQLGEEHPVLQLPTDHPRSSRASYRAARHTFTLPAGLVTRLQRQAQSQGAT
HHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHEEECCHHHHHHHHHHHHHCCHH
LFMALLSGFQGLLYRYTGQRDIRVGVPIANRHRAEIENIVGFFVNTQVLRTLMDGRMSLH
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
TLLDQTREAALGAQTHQDLPFERLVEALQPERNLNQNPLFQVMYNHLREDYRALEQLPGL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
KVENHELSEQAAQFELTLDTVEQPDGRLEATFTYAAELFEPATIGRLGNHYLLLLEQLAE
EECCCHHHHHHHEEEEEEECCCCCCCCEEEEHHHHHHHHCCHHHHHCCCHHHHHHHHHHH
HPQQNLGDIDILSEAERAQLKAWGINEQRYANTEPVHRLIERQVEVQPEAIALIFGDVEL
CHHHCCCCCHHHCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECEEE
SYGELNRRANRLAHRLIRLGVGPEVKVGIAVERSIDMVVGLLATLKAGGAYVPLDPEYPQ
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCEECCCCCCCCH
ERLAYMVADSGIGLLLTQSRVRSAIPHSDQCVVLELDRLDLEEESGSNPQVALHGYNLAY
HHHHHHHCCCCCEEEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECEEEE
IIYTSGSTGKPKGVSVAHHALVEHAQVAVGFFGLGSTDRMLQFSTINFDGFIEQLFPPLC
EEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCHHHHHHHHCHHHH
AGAAVVLRGPALWDSETFYRELIEKRITVADLTTAYWFMLVQDFARGGPRDYGLLRQVHA
CCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHC
GGEAMSPEGLKAWSEAGFDGVTLLNTYGPTEAAVTATVWNCSDYSQGNEISSQVSIVPIV
CCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEE
SIGSPLAARHIYLLDANLTPVSPGIPGELCIGGELLARGYLNRGGLTAERFIADPFDGGG
ECCCCHHHCEEEEEECCCCCCCCCCCCCEEECHHHHHHHHCCCCCCCHHHHCCCCCCCCC
GRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIEMQLLAQPEVREAVVVARES
CEEEECCCHHHHCCCCCEEEEECCCCEEEEEEEEEEECHHHHHHHCCCHHHHHHHHHHHH
ARGSNPAGGARLVAYVSLHAEAEMEVGRLREALGKVLPDYMLPSMIVVLESLPLNPSGKV
CCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DRKALPEPEFTHTEHYEAPRGEAEEVLAGIWAQVLGVAQVGRHDNFFELGGHSLAILQVQ
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEHHHHH
QKLQQALSISLPLRLHFENPLLKDIASAIQEKRSRASEKDAEQEDLLGMAELLDLLES
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHSSSLVQRRARLTPEQRERLAQRLAGAHAPALQSNIPCRNASARVPLSYAQERHWFLWQ
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCHHHHCCCCEEEEE
LEPLSTAYHLSGGLRLTGRVDIEALRWSFAALGRRHESLRTIFRVNSEGLPEQIIEDEPR
ECCCCEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCC
LEIPLTDFSGLPLEQARAQAGEEAGRIAGTPFDLTQGPLLRVALIRIAAEEHLLVVVMHH
EEEECCCCCCCCHHHHHHHCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
IISDAWSNRIVIDEFAAHYRARVQQEQEGEKQGQEPSLPALPIQYADYAIWQRNWLEAGE
HHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
KERQLAYWRSQLGEEHPVLQLPTDHPRSSRASYRAARHTFTLPAGLVTRLQRQAQSQGAT
HHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHEEECCHHHHHHHHHHHHHCCHH
LFMALLSGFQGLLYRYTGQRDIRVGVPIANRHRAEIENIVGFFVNTQVLRTLMDGRMSLH
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
TLLDQTREAALGAQTHQDLPFERLVEALQPERNLNQNPLFQVMYNHLREDYRALEQLPGL
HHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
KVENHELSEQAAQFELTLDTVEQPDGRLEATFTYAAELFEPATIGRLGNHYLLLLEQLAE
EECCCHHHHHHHEEEEEEECCCCCCCCEEEEHHHHHHHHCCHHHHHCCCHHHHHHHHHHH
HPQQNLGDIDILSEAERAQLKAWGINEQRYANTEPVHRLIERQVEVQPEAIALIFGDVEL
CHHHCCCCCHHHCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCCCCCEEEEEEECEEE
SYGELNRRANRLAHRLIRLGVGPEVKVGIAVERSIDMVVGLLATLKAGGAYVPLDPEYPQ
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHCCCEECCCCCCCCH
ERLAYMVADSGIGLLLTQSRVRSAIPHSDQCVVLELDRLDLEEESGSNPQVALHGYNLAY
HHHHHHHCCCCCEEEEEHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECEEEE
IIYTSGSTGKPKGVSVAHHALVEHAQVAVGFFGLGSTDRMLQFSTINFDGFIEQLFPPLC
EEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCEEEEEECCHHHHHHHHCHHHH
AGAAVVLRGPALWDSETFYRELIEKRITVADLTTAYWFMLVQDFARGGPRDYGLLRQVHA
CCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHC
GGEAMSPEGLKAWSEAGFDGVTLLNTYGPTEAAVTATVWNCSDYSQGNEISSQVSIVPIV
CCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEE
SIGSPLAARHIYLLDANLTPVSPGIPGELCIGGELLARGYLNRGGLTAERFIADPFDGGG
ECCCCHHHCEEEEEECCCCCCCCCCCCCEEECHHHHHHHHCCCCCCCHHHHCCCCCCCCC
GRLYRTGDLARWRSDGQIEYLGRLDHQVKIRGFRIELGEIEMQLLAQPEVREAVVVARES
CEEEECCCHHHHCCCCCEEEEECCCCEEEEEEEEEEECHHHHHHHCCCHHHHHHHHHHHH
ARGSNPAGGARLVAYVSLHAEAEMEVGRLREALGKVLPDYMLPSMIVVLESLPLNPSGKV
CCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DRKALPEPEFTHTEHYEAPRGEAEEVLAGIWAQVLGVAQVGRHDNFFELGGHSLAILQVQ
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEHHHHH
QKLQQALSISLPLRLHFENPLLKDIASAIQEKRSRASEKDAEQEDLLGMAELLDLLES
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA