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The map label for this gene is accA

Identifier: 82702933

GI number: 82702933

Start: 2070654

End: 2071622

Strand: Reverse

Name: accA

Synonym: Nmul_A1810

Alternate gene names: 82702933

Gene position: 2071622-2070654 (Counterclockwise)

Preceding gene: 82702935

Following gene: 82702932

Centisome position: 65.06

GC content: 54.59

Gene sequence:

>969_bases
ATGAAGATTACATTTCTGGATTTCGAGCAGCCGATTGCTGAGCTTGAAGCAAAAATAGAAGAATTGCGCTTTGCCCAGGA
TGATTCAGCGGTCGATATTTCAGCCGAAATCCTGCGTCTGCAAAAGAAAAGCCAGTCCCTCACCAACAGCATATACGGGA
AGCTCACGCCCTGGCAGATTTCACAAGTCGCGCGCCATCCGCAGCGCCCCTATACACTCGACTACATTCAGAATCTTTTC
ACGGATTTCGAAGAACTCCACGGCGATCGCGGCTTTGCCGATGACTACGCCATAATAGGCGGGTTGGCGCGTTTTGACGG
CCAGACAGTCATGGTTATCGGCCACCAGAAGGGGCGCGACACCAAGGAAAAAATTCATCGCAATTTTGGCATGCCCAAGC
CCGAAGGGTATCGCAAGGCGCTGCGGCTGATGCGTCTGGCAGAAAAATTCGCCATCCCGCTGTTCACGTTCATCGATACG
CCAGGCGCATATCCGGGCATCGGGGCGGAAGAACGCGGTCAATCAGAGGCGATTGGACACAATCTGTATGTAATGGCGGA
GTTGAAAGTGCCCGTGATCTGCACCGTTATCGGGGAGGGTGGGTCAGGTGGCGCGCTGGCGGTGGCAGTGGGCGACGCAA
TCCAGATGCTGCAATATGCAACCTATTCCGTCATTTCGCCCGAGGGCTGTGCCTCCATCCTTTGGAAAAGCGCTGACAAA
GCCCCTGAAGCTGCCGAGATCATGGGAATCACGGCGCACCGGCTCAAGACCCTGGGTCTGATAGACAAGATCATCGATGA
ACCTTCCGGGGGGGCTCACCGCGACCAGCCCGCTACCATGCAAGCCGTAAAGAAAGCCTTGCAGGACTCGCTCAAGCTCC
TGCAGGAATATTCCATCCACATGTTGCTGGAGAAACGCTTTGAGCGGCTGATGGGATATGGCCAGTTCAAGGAAGTCAAA
GTCAGATAA

Upstream 100 bases:

>100_bases
GGACAGGTAAATAGGACTCTTGGACATCCGGCTTACTGAGAGATTCCTCGGTTTTCGCCTGATCCTGTATCATTACCGTT
TCGGCTTAAACCGGTGTTTT

Downstream 100 bases:

>100_bases
TATCTCGCGCAGGGCGCAGCATGTATTGCGTACCCAGGTCCCAGCTGGCGATCACCTGACCATCGCTTTGAGCGGGGGAG
TGGATTCGGTGGTGTTGCTG

Product: acetyl-CoA carboxylase, carboxyl transferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKITFLDFEQPIAELEAKIEELRFAQDDSAVDISAEILRLQKKSQSLTNSIYGKLTPWQISQVARHPQRPYTLDYIQNLF
TDFEELHGDRGFADDYAIIGGLARFDGQTVMVIGHQKGRDTKEKIHRNFGMPKPEGYRKALRLMRLAEKFAIPLFTFIDT
PGAYPGIGAEERGQSEAIGHNLYVMAELKVPVICTVIGEGGSGGALAVAVGDAIQMLQYATYSVISPEGCASILWKSADK
APEAAEIMGITAHRLKTLGLIDKIIDEPSGGAHRDQPATMQAVKKALQDSLKLLQEYSIHMLLEKRFERLMGYGQFKEVK
VR

Sequences:

>Translated_322_residues
MKITFLDFEQPIAELEAKIEELRFAQDDSAVDISAEILRLQKKSQSLTNSIYGKLTPWQISQVARHPQRPYTLDYIQNLF
TDFEELHGDRGFADDYAIIGGLARFDGQTVMVIGHQKGRDTKEKIHRNFGMPKPEGYRKALRLMRLAEKFAIPLFTFIDT
PGAYPGIGAEERGQSEAIGHNLYVMAELKVPVICTVIGEGGSGGALAVAVGDAIQMLQYATYSVISPEGCASILWKSADK
APEAAEIMGITAHRLKTLGLIDKIIDEPSGGAHRDQPATMQAVKKALQDSLKLLQEYSIHMLLEKRFERLMGYGQFKEVK
VR
>Mature_322_residues
MKITFLDFEQPIAELEAKIEELRFAQDDSAVDISAEILRLQKKSQSLTNSIYGKLTPWQISQVARHPQRPYTLDYIQNLF
TDFEELHGDRGFADDYAIIGGLARFDGQTVMVIGHQKGRDTKEKIHRNFGMPKPEGYRKALRLMRLAEKFAIPLFTFIDT
PGAYPGIGAEERGQSEAIGHNLYVMAELKVPVICTVIGEGGSGGALAVAVGDAIQMLQYATYSVISPEGCASILWKSADK
APEAAEIMGITAHRLKTLGLIDKIIDEPSGGAHRDQPATMQAVKKALQDSLKLLQEYSIHMLLEKRFERLMGYGQFKEVK
VR

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=317, Percent_Identity=64.9842271293375, Blast_Score=420, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_NITMU (Q2Y814)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412499.1
- ProteinModelPortal:   Q2Y814
- SMR:   Q2Y814
- STRING:   Q2Y814
- GeneID:   3786361
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1810
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q2Y814
- BioCyc:   NMUL323848:NMUL_A1810-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35843; Mature: 35843

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITFLDFEQPIAELEAKIEELRFAQDDSAVDISAEILRLQKKSQSLTNSIYGKLTPWQI
CEEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SQVARHPQRPYTLDYIQNLFTDFEELHGDRGFADDYAIIGGLARFDGQTVMVIGHQKGRD
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCC
TKEKIHRNFGMPKPEGYRKALRLMRLAEKFAIPLFTFIDTPGAYPGIGAEERGQSEAIGH
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHEECCCCCCCCCCCCCCCCCHHCCC
NLYVMAELKVPVICTVIGEGGSGGALAVAVGDAIQMLQYATYSVISPEGCASILWKSADK
CEEEEEECCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
APEAAEIMGITAHRLKTLGLIDKIIDEPSGGAHRDQPATMQAVKKALQDSLKLLQEYSIH
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MLLEKRFERLMGYGQFKEVKVR
HHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MKITFLDFEQPIAELEAKIEELRFAQDDSAVDISAEILRLQKKSQSLTNSIYGKLTPWQI
CEEEEECHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SQVARHPQRPYTLDYIQNLFTDFEELHGDRGFADDYAIIGGLARFDGQTVMVIGHQKGRD
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCC
TKEKIHRNFGMPKPEGYRKALRLMRLAEKFAIPLFTFIDTPGAYPGIGAEERGQSEAIGH
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHEECCCCCCCCCCCCCCCCCHHCCC
NLYVMAELKVPVICTVIGEGGSGGALAVAVGDAIQMLQYATYSVISPEGCASILWKSADK
CEEEEEECCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
APEAAEIMGITAHRLKTLGLIDKIIDEPSGGAHRDQPATMQAVKKALQDSLKLLQEYSIH
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MLLEKRFERLMGYGQFKEVKVR
HHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA