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The map label for this gene is cbl [H]

Identifier: 82702862

GI number: 82702862

Start: 1991274

End: 1992218

Strand: Direct

Name: cbl [H]

Synonym: Nmul_A1739

Alternate gene names: 82702862

Gene position: 1991274-1992218 (Clockwise)

Preceding gene: 82702861

Following gene: 82702864

Centisome position: 62.54

GC content: 57.99

Gene sequence:

>945_bases
ATGAACTTTCAACAATTGCGCATCATCCATGAGACAGTCCGCCAGAACTATAACCTGACCGAAGCGGCCAATGCCCTGTT
CACTTCCCAGTCCGGCGTCAGCAAACACATCAAGGATCTTGAAGATGAATTGGGCGTCGAATTATTCGTGCGCAAAGGCA
AACGGCTGCTCGGCCTGACCAATCCGGGCAAGGAGTTGATAGAGATTGTCGAGCGCATCCTTCTGGATGCAAAGAATGTC
AAGCGTCTGGCTGAACAGTTCAGCAAGCGGGATAAAGGACGGCTGACCATCGCCACTACCCACACGCAGGCGCAGTACGC
ACTCCCTACGGTGGTCACGCAATTCAAGAAAACCTTTCCCCAGGTGCATCTCGTCCTGCACCAGGCCAGCCCCGGCGAAA
TCGTATCGATGCTGCTGGACGGGGTGGCCGATATCGGCATTGCCACCGAAGCATTGGAGAGTGTCGCAGAACTGGCCTCT
TTTCCTTATTACTCGTGGCACCACGCTGTCATTGTGCCGCCCGGACACCCGCTGGAAGCAATACAGCCGCTCACGCTTGA
AGGCATTGCAGAGTTCCCGATCATCACTTATCACGAAGGCTTTACCGGCCGGGCGGGAATTGATCAGACGTTCGCCGGGG
CAGGATTGGTGCTCGACATCGCCATGTCCGCACTCGATGCGGACGTCATCAAAACGTACGTGGAACTGGGGCTGGGGGTG
GGTCTCGTTGCGTCGATGGCCTTCAATCCCGTGCGGGACACCCGGCTGACGCTGCTGGACAGTTCCCACCTGTTCGGGCA
AAACATCACCCACATCTCGATCCGCCGCGGTCATTACCTGCGGGGATACGCCTACCGGTTCATCGAGCTTTGCCTTCCTT
CCCTGACGGAAGCCGCTATCCGCGCGGGCGTGAGGCCGCGAGCGGGAGTGGAACTGGGCGACTGA

Upstream 100 bases:

>100_bases
ATCACACCCCCGGAAAGCCATACTGATTTTTGAATGAGCATTCCACATCCATCATTGCTCGAAACCGATCACGACAATAA
CAGGCTGCAGGCTTATAAAT

Downstream 100 bases:

>100_bases
TTGCCGAACCGATCGGAAAACCGTTTGAACCGCAGGAGATATAGGCTTTCTCAAGCTTATAGTTCTATGCGTCTTCCCCC
AGAAAACCGCCACTCTGATG

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MNFQQLRIIHETVRQNYNLTEAANALFTSQSGVSKHIKDLEDELGVELFVRKGKRLLGLTNPGKELIEIVERILLDAKNV
KRLAEQFSKRDKGRLTIATTHTQAQYALPTVVTQFKKTFPQVHLVLHQASPGEIVSMLLDGVADIGIATEALESVAELAS
FPYYSWHHAVIVPPGHPLEAIQPLTLEGIAEFPIITYHEGFTGRAGIDQTFAGAGLVLDIAMSALDADVIKTYVELGLGV
GLVASMAFNPVRDTRLTLLDSSHLFGQNITHISIRRGHYLRGYAYRFIELCLPSLTEAAIRAGVRPRAGVELGD

Sequences:

>Translated_314_residues
MNFQQLRIIHETVRQNYNLTEAANALFTSQSGVSKHIKDLEDELGVELFVRKGKRLLGLTNPGKELIEIVERILLDAKNV
KRLAEQFSKRDKGRLTIATTHTQAQYALPTVVTQFKKTFPQVHLVLHQASPGEIVSMLLDGVADIGIATEALESVAELAS
FPYYSWHHAVIVPPGHPLEAIQPLTLEGIAEFPIITYHEGFTGRAGIDQTFAGAGLVLDIAMSALDADVIKTYVELGLGV
GLVASMAFNPVRDTRLTLLDSSHLFGQNITHISIRRGHYLRGYAYRFIELCLPSLTEAAIRAGVRPRAGVELGD
>Mature_314_residues
MNFQQLRIIHETVRQNYNLTEAANALFTSQSGVSKHIKDLEDELGVELFVRKGKRLLGLTNPGKELIEIVERILLDAKNV
KRLAEQFSKRDKGRLTIATTHTQAQYALPTVVTQFKKTFPQVHLVLHQASPGEIVSMLLDGVADIGIATEALESVAELAS
FPYYSWHHAVIVPPGHPLEAIQPLTLEGIAEFPIITYHEGFTGRAGIDQTFAGAGLVLDIAMSALDADVIKTYVELGLGV
GLVASMAFNPVRDTRLTLLDSSHLFGQNITHISIRRGHYLRGYAYRFIELCLPSLTEAAIRAGVRPRAGVELGD

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=304, Percent_Identity=55.5921052631579, Blast_Score=352, Evalue=1e-98,
Organism=Escherichia coli, GI1787530, Length=312, Percent_Identity=45.5128205128205, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI1788481, Length=244, Percent_Identity=29.9180327868852, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI157672245, Length=224, Percent_Identity=29.9107142857143, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367136, Length=232, Percent_Identity=25.4310344827586, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790399, Length=252, Percent_Identity=25.3968253968254, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789204, Length=244, Percent_Identity=28.6885245901639, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788887, Length=239, Percent_Identity=27.1966527196653, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082132, Length=140, Percent_Identity=30.7142857142857, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788748, Length=258, Percent_Identity=24.8062015503876, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34542; Mature: 34542

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQQLRIIHETVRQNYNLTEAANALFTSQSGVSKHIKDLEDELGVELFVRKGKRLLGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHCCCEEEECC
NPGKELIEIVERILLDAKNVKRLAEQFSKRDKGRLTIATTHTQAQYALPTVVTQFKKTFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
QVHLVLHQASPGEIVSMLLDGVADIGIATEALESVAELASFPYYSWHHAVIVPPGHPLEA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHH
IQPLTLEGIAEFPIITYHEGFTGRAGIDQTFAGAGLVLDIAMSALDADVIKTYVELGLGV
CCCCCCCCHHCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
GLVASMAFNPVRDTRLTLLDSSHLFGQNITHISIRRGHYLRGYAYRFIELCLPSLTEAAI
HHHHHHHCCCCCCCEEEEEECCHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RAGVRPRAGVELGD
HCCCCCCCCCCCCC
>Mature Secondary Structure
MNFQQLRIIHETVRQNYNLTEAANALFTSQSGVSKHIKDLEDELGVELFVRKGKRLLGLT
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHCCCEEEECC
NPGKELIEIVERILLDAKNVKRLAEQFSKRDKGRLTIATTHTQAQYALPTVVTQFKKTFP
CCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCC
QVHLVLHQASPGEIVSMLLDGVADIGIATEALESVAELASFPYYSWHHAVIVPPGHPLEA
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHH
IQPLTLEGIAEFPIITYHEGFTGRAGIDQTFAGAGLVLDIAMSALDADVIKTYVELGLGV
CCCCCCCCHHCCCEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCH
GLVASMAFNPVRDTRLTLLDSSHLFGQNITHISIRRGHYLRGYAYRFIELCLPSLTEAAI
HHHHHHHCCCCCCCEEEEEECCHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RAGVRPRAGVELGD
HCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]