Click here to switch to the map view.

The map label for this gene is aatA [H]

Identifier: 82702489

GI number: 82702489

Start: 1546652

End: 1547845

Strand: Reverse

Name: aatA [H]

Synonym: Nmul_A1360

Alternate gene names: 82702489

Gene position: 1547845-1546652 (Counterclockwise)

Preceding gene: 82702491

Following gene: 82702487

Centisome position: 48.61

GC content: 56.37

Gene sequence:

>1194_bases
GTGGAACTCTCAAAGCGCGTTCAGGCCATCAAGCCCTCCCCTACTCTGGCTGTCACTGCCCGAGCAGCACGCCTGAAAGC
GGAAGGCAAGGATATTATTGGACTGGGCGCCGGCGAGCCCGATTTCGATACCCCCCAGCACATCAAGGATGCCGCGGTTG
CCGCGATTCAGCGCGGTTTTACGAAATATACGGCTGTCGGTGGAACACCCGGCCTCAAGAATGCGATCATCGCCAAGTTC
AAGCGCGAAAACGGCTTCGACTATACTGCGGGACAAATTCTGGTTTCATGCGGAGGCAAGCAAAGCTTTTTCAATCTCAC
ACTGTCTGTCATCAATCCTGGGGATGAGGTCATCATACCGGCGCCCTACTGGGTCTCTTATCCTGACATCGTCCTGATCG
CCGAAGGCAAGCCGGTCATTGTCGAGGCGGGTATCGAGCAGGGTTTCAAAATTACAGCGGCTCAGCTCGAGCGAGCCATT
ACGCCGAAAACCCGGATGTTCGTCATCAACAGCCCCAGCAACCCCTCTGGCGGTGTCTACACGCTGGACGAACTCAAGGC
ATTGGGAGAAGTTCTACTCGGACATCCCCATATCCTGATTGCCACGGATGACATGTACGAACACATCCTGCTATCGGAGG
GCAAGTTCGTCAATATTCTGAATGCCTGTCCAGCCCTGTATCCCCGCACGGTGGTGCTCAACGGGGTTTCCAAGGCATAT
GCCATGACAGGCTGGCGGATCGGTTATTGCGCGGGTCCCGCTCACATCATTACCGCAATGGAGAATGTCCAGTCGCAGAG
CACTTCAAACCCTGCCTCTATTTCCCAGGTCGCGGCTGAAACAGCGCTGAATGGCGATCAATCCTGTATCACCCCGATGG
TGGAAGCGTTCCGGCAGCGGAACCGTTTCGTGACTGATGCCCTCAATGGTATCGCCGGCATCCGTTGCCTGCTGTCCGAA
GGAGCATTCTACGCATTTGCCGATGCACGGGAAGCAATCGCACGTTTGCACGGTAATGGGATGATCAAGGATCGCAGCGA
TATCGCCTTTAGCGAATATCTGCTGGAACAGGGGGGGGTCGCGGTGGTGCCAGGCTCCGCTTTTGGGAGCGAAGGTTACA
TCAGGCTCTCCTTTGCCACCGCAATGTCCAACCTGGAAGGTGCGCTAGGACGCATGGCAAGGCTGCTGGGCTGA

Upstream 100 bases:

>100_bases
GTTTTTTTCATCTCCTCCAACCACCGCATGCAGCATCACCCGCGACTTGATGGCTGATTTTATCACGCAGCACAAGTGCC
ATTAGCATAAGGACATTATT

Downstream 100 bases:

>100_bases
AAATCTTCCACACTTGAAGGTGACCTTGCCCGCCTCGCCCGAAATTTTCTTACCAATAACCGGGTGGAATCATCTAAAGT
CCCGTGTCCCATACCTACTG

Product: class I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MELSKRVQAIKPSPTLAVTARAARLKAEGKDIIGLGAGEPDFDTPQHIKDAAVAAIQRGFTKYTAVGGTPGLKNAIIAKF
KRENGFDYTAGQILVSCGGKQSFFNLTLSVINPGDEVIIPAPYWVSYPDIVLIAEGKPVIVEAGIEQGFKITAAQLERAI
TPKTRMFVINSPSNPSGGVYTLDELKALGEVLLGHPHILIATDDMYEHILLSEGKFVNILNACPALYPRTVVLNGVSKAY
AMTGWRIGYCAGPAHIITAMENVQSQSTSNPASISQVAAETALNGDQSCITPMVEAFRQRNRFVTDALNGIAGIRCLLSE
GAFYAFADAREAIARLHGNGMIKDRSDIAFSEYLLEQGGVAVVPGSAFGSEGYIRLSFATAMSNLEGALGRMARLLG

Sequences:

>Translated_397_residues
MELSKRVQAIKPSPTLAVTARAARLKAEGKDIIGLGAGEPDFDTPQHIKDAAVAAIQRGFTKYTAVGGTPGLKNAIIAKF
KRENGFDYTAGQILVSCGGKQSFFNLTLSVINPGDEVIIPAPYWVSYPDIVLIAEGKPVIVEAGIEQGFKITAAQLERAI
TPKTRMFVINSPSNPSGGVYTLDELKALGEVLLGHPHILIATDDMYEHILLSEGKFVNILNACPALYPRTVVLNGVSKAY
AMTGWRIGYCAGPAHIITAMENVQSQSTSNPASISQVAAETALNGDQSCITPMVEAFRQRNRFVTDALNGIAGIRCLLSE
GAFYAFADAREAIARLHGNGMIKDRSDIAFSEYLLEQGGVAVVPGSAFGSEGYIRLSFATAMSNLEGALGRMARLLG
>Mature_397_residues
MELSKRVQAIKPSPTLAVTARAARLKAEGKDIIGLGAGEPDFDTPQHIKDAAVAAIQRGFTKYTAVGGTPGLKNAIIAKF
KRENGFDYTAGQILVSCGGKQSFFNLTLSVINPGDEVIIPAPYWVSYPDIVLIAEGKPVIVEAGIEQGFKITAAQLERAI
TPKTRMFVINSPSNPSGGVYTLDELKALGEVLLGHPHILIATDDMYEHILLSEGKFVNILNACPALYPRTVVLNGVSKAY
AMTGWRIGYCAGPAHIITAMENVQSQSTSNPASISQVAAETALNGDQSCITPMVEAFRQRNRFVTDALNGIAGIRCLLSE
GAFYAFADAREAIARLHGNGMIKDRSDIAFSEYLLEQGGVAVVPGSAFGSEGYIRLSFATAMSNLEGALGRMARLLG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=429, Percent_Identity=24.009324009324, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI169881279, Length=429, Percent_Identity=24.009324009324, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI56713254, Length=416, Percent_Identity=25, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI56713256, Length=416, Percent_Identity=25, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI169881281, Length=416, Percent_Identity=21.3942307692308, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4507369, Length=375, Percent_Identity=22.9333333333333, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=27.7333333333333, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1788722, Length=364, Percent_Identity=27.7472527472527, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788627, Length=398, Percent_Identity=27.8894472361809, Blast_Score=125, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17567369, Length=402, Percent_Identity=26.1194029850746, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI71994472, Length=384, Percent_Identity=27.8645833333333, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=417, Percent_Identity=26.8585131894484, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=383, Percent_Identity=22.7154046997389, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=394, Percent_Identity=26.1421319796954, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28573069, Length=414, Percent_Identity=25.1207729468599, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24646114, Length=414, Percent_Identity=25.1207729468599, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573067, Length=414, Percent_Identity=25.1207729468599, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573065, Length=414, Percent_Identity=25.1207729468599, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859735, Length=388, Percent_Identity=22.680412371134, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42309; Mature: 42309

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSKRVQAIKPSPTLAVTARAARLKAEGKDIIGLGAGEPDFDTPQHIKDAAVAAIQRGF
CCHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
TKYTAVGGTPGLKNAIIAKFKRENGFDYTAGQILVSCGGKQSFFNLTLSVINPGDEVIIP
HHEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEEEECCCCCEEEC
APYWVSYPDIVLIAEGKPVIVEAGIEQGFKITAAQLERAITPKTRMFVINSPSNPSGGVY
CCCEECCCCEEEEECCCCEEEECCCCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCEE
TLDELKALGEVLLGHPHILIATDDMYEHILLSEGKFVNILNACPALYPRTVVLNGVSKAY
EHHHHHHHHHHHHCCCEEEEEECHHHHHHHHCCCCEEEHHHHCCCCCCCEEEECCCHHHH
AMTGWRIGYCAGPAHIITAMENVQSQSTSNPASISQVAAETALNGDQSCITPMVEAFRQR
HHCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
NRFVTDALNGIAGIRCLLSEGAFYAFADAREAIARLHGNGMIKDRSDIAFSEYLLEQGGV
CCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCEECCCCHHHHHHHHHCCCE
AVVPGSAFGSEGYIRLSFATAMSNLEGALGRMARLLG
EEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MELSKRVQAIKPSPTLAVTARAARLKAEGKDIIGLGAGEPDFDTPQHIKDAAVAAIQRGF
CCHHHHHHHCCCCCCEEEEEHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
TKYTAVGGTPGLKNAIIAKFKRENGFDYTAGQILVSCGGKQSFFNLTLSVINPGDEVIIP
HHEEECCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEEEEEECCCCCEEEC
APYWVSYPDIVLIAEGKPVIVEAGIEQGFKITAAQLERAITPKTRMFVINSPSNPSGGVY
CCCEECCCCEEEEECCCCEEEECCCCCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCEE
TLDELKALGEVLLGHPHILIATDDMYEHILLSEGKFVNILNACPALYPRTVVLNGVSKAY
EHHHHHHHHHHHHCCCEEEEEECHHHHHHHHCCCCEEEHHHHCCCCCCCEEEECCCHHHH
AMTGWRIGYCAGPAHIITAMENVQSQSTSNPASISQVAAETALNGDQSCITPMVEAFRQR
HHCCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
NRFVTDALNGIAGIRCLLSEGAFYAFADAREAIARLHGNGMIKDRSDIAFSEYLLEQGGV
CCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCEECCCCHHHHHHHHHCCCE
AVVPGSAFGSEGYIRLSFATAMSNLEGALGRMARLLG
EEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA