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The map label for this gene is flhA [H]

Identifier: 82702439

GI number: 82702439

Start: 1500624

End: 1502702

Strand: Direct

Name: flhA [H]

Synonym: Nmul_A1310

Alternate gene names: 82702439

Gene position: 1500624-1502702 (Clockwise)

Preceding gene: 82702438

Following gene: 82702440

Centisome position: 47.13

GC content: 57.86

Gene sequence:

>2079_bases
ATGACTGCGATGACAAAACTAACTTACCTGTTTAGCGGTGCGAGGGCGCGCAGCCTTGCAGGTCCGCTGCTGATATTCAT
GATCCTCGGCATGATGGTACTGCCACTGCCCGCGTTTTTACTGGACATGATGTTCACTTTCAACATCGCGCTCTCCATCA
TGGTGCTGCTGGTTAGCATCCATACGCACAAGCCGCTGGATTTTGCCGTGTTTCCCACAGTGCTGCTCCTTTCAACGCTG
CTGCGATTGTCGCTCAACGTGGCATCTACCCGCGTGGTGCTGATGCAAGGCCATACCGGGCCGGATGCGGCAGGAAAAGT
CATCGAGGCATTCGGTCATTACCTCGTCGGCGGGAATTATACGGTCGGCATAGTTGTGTTCGTTATTCTGGTGGTGATCA
ACTTTATCGTCATTACCAAGGGTGCCGGTCGCATTGCGGAAGTTTCCGCGCGCTTTACGCTGGATGCCATGCCGGGCAAG
CAGATGGCGATCGATGCGGATCTCAACGCCGGCCTCATCGGTGAGGAGGAGGCGGGCAGGCGGCGCGTCTCCATTGCCCA
GGAGGCGGAATTTTACGGCTCCATGGATGGCGCGAGCAAATTTGTAAGGGGAGATGCGATAGCGGGAATTCTCATCCTCT
TTATTAATGTCGTTGGCGGATTGGTAGTCGGCGTTCTGCAGCATGACCTCGATCTTGCTACCGCCGCCAGAAATTACACC
CTGCTTGCCATCGGTGACGGACTGGTGGCCCAGATTCCGGCGCTCATTATCTCTACCGCCGCCGGCCTGGTAGTAAGCCG
CGTCGGTACGGATGAGGATATCAGCACTCAACTGGCAGGCCAGCTTTTCTCAAAGCCCCAGGTATTGGCTTTGACTGCCG
CTATCATCGGTCTCATGGGCCTGATACCCGGTATGCCTCATATTGCCTTTCTGCTGCTGGCCGCATTGTGCGGCGGGGGC
GCCTATCTGATGGAACAGCGCCGCAAGCGGCTTGTGTCGCAGGCGCCGACAGCTCCCGTTATCCAAGCGGAGGCGCAGGA
CGCCAGTTGGGATGATGTCATGCCCGTGGACATACTGGGACTAGAGGTGGGCTATCGCCTGATTTCGCTCGTGGACAAGA
CCCAGGACGGGGAGCTTCTCGGGCGGATCAAAGGCGTGCGCAAGAAATTCGCCCAGGAGGTCGGGTATCTTCCGCCGACT
GTTCATATCCGTGACAATCTGGAACTGCGCCCTAACGGGTACCGGATAACGCTCAAGGGCGTCAATATTGGAACCGGTGA
AGTCAATGTGGGGCAGTATCTCGCCATCAATCCGGGCATCGTATCCGGCAATGTGCCTGGTCTTGCCACCACCGATCCCG
CTTTCGGGCTGCCCGCTGTCTGGATAGAAGCAGGCCAGCGCGAGCGTGCCCAGTCACTGGGATATACGGTGGTCGATGCG
GGTACTGTCGTTGCCACCCATCTCAATCATCTGGTGCACAGCCACGCTGCCGAATTGCTGGGCCGCTCCGAAGTGCAGCA
ACTGGTGGATCGCCTCTCCAAGGATTCTCCCAAGCTGGTGGAAGATATGATTCCGAAGCTGCTCCCGCTCTCCACCTTGC
AGAAAGTGCTGCAGAATCTGCTCGAGGAGAAGGTGCATATACGCGACATGCGAAGCATCGTCGAAACCTTGGCCGAGCAC
GCTTCGAAAGTTCAGGATGCGCATGAACTGACGGCGCTGGTGCGCATTGCGTTGGGGCGCTCAATCGTTCAGCAGATATG
GCCCCAAGCCAGTGAGTTGCAGGTGATGGCGCTTGATTCCGGACTGGAAAGGTTGCTGACCCAAGCTTTGCAAGCCAGCC
CGACGGGGGCTGGGATCGAGCCGGGACTCGCCGATACCCTCATTCGGGAGGCAGCTGGCGCCAGCCAGCGGCAGGAGCAG
GTGGGGCTGGTTCCCGTGTTGCTGGTGCCAGCGCCGCTTCGAACCTTGCTGGCGCGTTTTCTGCGCCGTGCCGTTCCTCA
ACTGAAAATACTGTCGCATGCGGAAGTACCCGATTCAAGCAATATTAAAGTCACTTCGATTCTTGGAGCCAGAGCATGA

Upstream 100 bases:

>100_bases
GCAAGGCTCCCGTTTTGCCGGAACTTGACGTGCCGGTTGAGCTGGATCCGGAAAACAAAGCGTTCAAGGAAGCGGGAAAA
ACTGGAAAACCTGAATAACG

Downstream 100 bases:

>100_bases
CTATCAAACGATTTTTTGCCAAAACAACCAGCGAAGCATTGCGCATGGTACGCGATGAGCTCGGAGCCGACGGGGTGATT
CTGTCGAATCGAGCGGTAGA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MTAMTKLTYLFSGARARSLAGPLLIFMILGMMVLPLPAFLLDMMFTFNIALSIMVLLVSIHTHKPLDFAVFPTVLLLSTL
LRLSLNVASTRVVLMQGHTGPDAAGKVIEAFGHYLVGGNYTVGIVVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGK
QMAIDADLNAGLIGEEEAGRRRVSIAQEAEFYGSMDGASKFVRGDAIAGILILFINVVGGLVVGVLQHDLDLATAARNYT
LLAIGDGLVAQIPALIISTAAGLVVSRVGTDEDISTQLAGQLFSKPQVLALTAAIIGLMGLIPGMPHIAFLLLAALCGGG
AYLMEQRRKRLVSQAPTAPVIQAEAQDASWDDVMPVDILGLEVGYRLISLVDKTQDGELLGRIKGVRKKFAQEVGYLPPT
VHIRDNLELRPNGYRITLKGVNIGTGEVNVGQYLAINPGIVSGNVPGLATTDPAFGLPAVWIEAGQRERAQSLGYTVVDA
GTVVATHLNHLVHSHAAELLGRSEVQQLVDRLSKDSPKLVEDMIPKLLPLSTLQKVLQNLLEEKVHIRDMRSIVETLAEH
ASKVQDAHELTALVRIALGRSIVQQIWPQASELQVMALDSGLERLLTQALQASPTGAGIEPGLADTLIREAAGASQRQEQ
VGLVPVLLVPAPLRTLLARFLRRAVPQLKILSHAEVPDSSNIKVTSILGARA

Sequences:

>Translated_692_residues
MTAMTKLTYLFSGARARSLAGPLLIFMILGMMVLPLPAFLLDMMFTFNIALSIMVLLVSIHTHKPLDFAVFPTVLLLSTL
LRLSLNVASTRVVLMQGHTGPDAAGKVIEAFGHYLVGGNYTVGIVVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGK
QMAIDADLNAGLIGEEEAGRRRVSIAQEAEFYGSMDGASKFVRGDAIAGILILFINVVGGLVVGVLQHDLDLATAARNYT
LLAIGDGLVAQIPALIISTAAGLVVSRVGTDEDISTQLAGQLFSKPQVLALTAAIIGLMGLIPGMPHIAFLLLAALCGGG
AYLMEQRRKRLVSQAPTAPVIQAEAQDASWDDVMPVDILGLEVGYRLISLVDKTQDGELLGRIKGVRKKFAQEVGYLPPT
VHIRDNLELRPNGYRITLKGVNIGTGEVNVGQYLAINPGIVSGNVPGLATTDPAFGLPAVWIEAGQRERAQSLGYTVVDA
GTVVATHLNHLVHSHAAELLGRSEVQQLVDRLSKDSPKLVEDMIPKLLPLSTLQKVLQNLLEEKVHIRDMRSIVETLAEH
ASKVQDAHELTALVRIALGRSIVQQIWPQASELQVMALDSGLERLLTQALQASPTGAGIEPGLADTLIREAAGASQRQEQ
VGLVPVLLVPAPLRTLLARFLRRAVPQLKILSHAEVPDSSNIKVTSILGARA
>Mature_691_residues
TAMTKLTYLFSGARARSLAGPLLIFMILGMMVLPLPAFLLDMMFTFNIALSIMVLLVSIHTHKPLDFAVFPTVLLLSTLL
RLSLNVASTRVVLMQGHTGPDAAGKVIEAFGHYLVGGNYTVGIVVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGKQ
MAIDADLNAGLIGEEEAGRRRVSIAQEAEFYGSMDGASKFVRGDAIAGILILFINVVGGLVVGVLQHDLDLATAARNYTL
LAIGDGLVAQIPALIISTAAGLVVSRVGTDEDISTQLAGQLFSKPQVLALTAAIIGLMGLIPGMPHIAFLLLAALCGGGA
YLMEQRRKRLVSQAPTAPVIQAEAQDASWDDVMPVDILGLEVGYRLISLVDKTQDGELLGRIKGVRKKFAQEVGYLPPTV
HIRDNLELRPNGYRITLKGVNIGTGEVNVGQYLAINPGIVSGNVPGLATTDPAFGLPAVWIEAGQRERAQSLGYTVVDAG
TVVATHLNHLVHSHAAELLGRSEVQQLVDRLSKDSPKLVEDMIPKLLPLSTLQKVLQNLLEEKVHIRDMRSIVETLAEHA
SKVQDAHELTALVRIALGRSIVQQIWPQASELQVMALDSGLERLLTQALQASPTGAGIEPGLADTLIREAAGASQRQEQV
GLVPVLLVPAPLRTLLARFLRRAVPQLKILSHAEVPDSSNIKVTSILGARA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=694, Percent_Identity=62.3919308357349, Blast_Score=848, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 73941; Mature: 73810

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAMTKLTYLFSGARARSLAGPLLIFMILGMMVLPLPAFLLDMMFTFNIALSIMVLLVSI
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTHKPLDFAVFPTVLLLSTLLRLSLNVASTRVVLMQGHTGPDAAGKVIEAFGHYLVGGNY
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCEEECCCC
TVGIVVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLIGEEEAGR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHHHCC
RRVSIAQEAEFYGSMDGASKFVRGDAIAGILILFINVVGGLVVGVLQHDLDLATAARNYT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LLAIGDGLVAQIPALIISTAAGLVVSRVGTDEDISTQLAGQLFSKPQVLALTAAIIGLMG
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LIPGMPHIAFLLLAALCGGGAYLMEQRRKRLVSQAPTAPVIQAEAQDASWDDVMPVDILG
HCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHH
LEVGYRLISLVDKTQDGELLGRIKGVRKKFAQEVGYLPPTVHIRDNLELRPNGYRITLKG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCEEEEEEE
VNIGTGEVNVGQYLAINPGIVSGNVPGLATTDPAFGLPAVWIEAGQRERAQSLGYTVVDA
EEECCCCCCCCCEEEECCCEECCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHCCCEEEEC
GTVVATHLNHLVHSHAAELLGRSEVQQLVDRLSKDSPKLVEDMIPKLLPLSTLQKVLQNL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHH
LEEKVHIRDMRSIVETLAEHASKVQDAHELTALVRIALGRSIVQQIWPQASELQVMALDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHH
GLERLLTQALQASPTGAGIEPGLADTLIREAAGASQRQEQVGLVPVLLVPAPLRTLLARF
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCEEEEECCCCHHHHHHHH
LRRAVPQLKILSHAEVPDSSNIKVTSILGARA
HHHHCCHHHHHHCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
TAMTKLTYLFSGARARSLAGPLLIFMILGMMVLPLPAFLLDMMFTFNIALSIMVLLVSI
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTHKPLDFAVFPTVLLLSTLLRLSLNVASTRVVLMQGHTGPDAAGKVIEAFGHYLVGGNY
HCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCEEECCCC
TVGIVVFVILVVINFIVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLIGEEEAGR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHHHCC
RRVSIAQEAEFYGSMDGASKFVRGDAIAGILILFINVVGGLVVGVLQHDLDLATAARNYT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LLAIGDGLVAQIPALIISTAAGLVVSRVGTDEDISTQLAGQLFSKPQVLALTAAIIGLMG
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LIPGMPHIAFLLLAALCGGGAYLMEQRRKRLVSQAPTAPVIQAEAQDASWDDVMPVDILG
HCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHH
LEVGYRLISLVDKTQDGELLGRIKGVRKKFAQEVGYLPPTVHIRDNLELRPNGYRITLKG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCEEEEEEE
VNIGTGEVNVGQYLAINPGIVSGNVPGLATTDPAFGLPAVWIEAGQRERAQSLGYTVVDA
EEECCCCCCCCCEEEECCCEECCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHCCCEEEEC
GTVVATHLNHLVHSHAAELLGRSEVQQLVDRLSKDSPKLVEDMIPKLLPLSTLQKVLQNL
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHH
LEEKVHIRDMRSIVETLAEHASKVQDAHELTALVRIALGRSIVQQIWPQASELQVMALDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHH
GLERLLTQALQASPTGAGIEPGLADTLIREAAGASQRQEQVGLVPVLLVPAPLRTLLARF
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHCCCEEEEECCCCHHHHHHHH
LRRAVPQLKILSHAEVPDSSNIKVTSILGARA
HHHHCCHHHHHHCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]