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The map label for this gene is pgsA [H]

Identifier: 82702401

GI number: 82702401

Start: 1463368

End: 1463940

Strand: Direct

Name: pgsA [H]

Synonym: Nmul_A1272

Alternate gene names: 82702401

Gene position: 1463368-1463940 (Clockwise)

Preceding gene: 82702400

Following gene: 82702402

Centisome position: 45.96

GC content: 52.71

Gene sequence:

>573_bases
ATGCCTTTTAATCTGCCCAACGTACTCACCTGGCTGCGCATCGTGGCGATTCCGCTGTTCGTGGGTATATTCTATTTTCC
CTCGACCTGGTTATCGCATGCGGACCAGAACCTGATCGCAACCATTATCTTTACTGGCGCCGCCATTACCGATTGGCTGG
ATGGTTATCTTGCGCGCGTGCTGCGGCAGACCTCGGCGTTCGGTGCGTTCCTCGACCCCGTTGCCGACAAGCTCATGGTC
GCTGCCGCGCTCATCGTGCTGGTTTACCTGAGCAGGCTGGATGCGCTCATCGCTTTCATCATCATAGGGCGGGAAATCAC
TATTTCGGCCTTGCGCGAATGGATGGCCCAGATCGGCAAAGGCAAGAGCGTGGCCGTTTCCTTTCTGGGAAAATTGAAAA
CCGTATCGCAAATGGCGGCCATTCCGCTGCTGCTATATGACGAAAAAATAGATGAAAACTTCGATTCTCATGAAATAGGC
ACTTGGCTGATCTATCTTGCGGCAATACTGACATTGTGGTCGATGGCCTATTACCTCAAGATCGCGATTCCCCAGGTGGT
AAAGCATGGATGA

Upstream 100 bases:

>100_bases
TTACAGGGAACTGCATTGAATCTTGCCCAGCCTGCAGGCTCAGTGGCTTGCAGCGGGACGCTTTCCAGATTCGTTTTTTA
ATAGCATATTCCCGATCCTT

Downstream 100 bases:

>100_bases
GCAAGCCGGGCCAAAGGAAGGAGAAAAAATGCAATCACTATACAATCCGGACATCTACCCCGATGGGATTCGGGAAATGA
TATGCGAGTCGGGAGAAACG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MPFNLPNVLTWLRIVAIPLFVGIFYFPSTWLSHADQNLIATIIFTGAAITDWLDGYLARVLRQTSAFGAFLDPVADKLMV
AAALIVLVYLSRLDALIAFIIIGREITISALREWMAQIGKGKSVAVSFLGKLKTVSQMAAIPLLLYDEKIDENFDSHEIG
TWLIYLAAILTLWSMAYYLKIAIPQVVKHG

Sequences:

>Translated_190_residues
MPFNLPNVLTWLRIVAIPLFVGIFYFPSTWLSHADQNLIATIIFTGAAITDWLDGYLARVLRQTSAFGAFLDPVADKLMV
AAALIVLVYLSRLDALIAFIIIGREITISALREWMAQIGKGKSVAVSFLGKLKTVSQMAAIPLLLYDEKIDENFDSHEIG
TWLIYLAAILTLWSMAYYLKIAIPQVVKHG
>Mature_189_residues
PFNLPNVLTWLRIVAIPLFVGIFYFPSTWLSHADQNLIATIIFTGAAITDWLDGYLARVLRQTSAFGAFLDPVADKLMVA
AALIVLVYLSRLDALIAFIIIGREITISALREWMAQIGKGKSVAVSFLGKLKTVSQMAAIPLLLYDEKIDENFDSHEIGT
WLIYLAAILTLWSMAYYLKIAIPQVVKHG

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=184, Percent_Identity=50, Blast_Score=160, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21158; Mature: 21027

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNLPNVLTWLRIVAIPLFVGIFYFPSTWLSHADQNLIATIIFTGAAITDWLDGYLARV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LRQTSAFGAFLDPVADKLMVAAALIVLVYLSRLDALIAFIIIGREITISALREWMAQIGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
GKSVAVSFLGKLKTVSQMAAIPLLLYDEKIDENFDSHEIGTWLIYLAAILTLWSMAYYLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IAIPQVVKHG
HHHHHHHCCC
>Mature Secondary Structure 
PFNLPNVLTWLRIVAIPLFVGIFYFPSTWLSHADQNLIATIIFTGAAITDWLDGYLARV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LRQTSAFGAFLDPVADKLMVAAALIVLVYLSRLDALIAFIIIGREITISALREWMAQIGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
GKSVAVSFLGKLKTVSQMAAIPLLLYDEKIDENFDSHEIGTWLIYLAAILTLWSMAYYLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IAIPQVVKHG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]