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The map label for this gene is efp

Identifier: 82702397

GI number: 82702397

Start: 1459931

End: 1460497

Strand: Reverse

Name: efp

Synonym: Nmul_A1268

Alternate gene names: 82702397

Gene position: 1460497-1459931 (Counterclockwise)

Preceding gene: 82702403

Following gene: 82702395

Centisome position: 45.87

GC content: 53.26

Gene sequence:

>567_bases
ATGGCTAAAGTTCTTGCTACCGAAATTCGCGTCGGCAATCTGATTGAATGGGACAAGCGAATCTGGCGCGTACTGAAATG
TTACCACGTCCATGTTGGCGGCCGGGGGGGAGCCTTCATGCAGGTGGAAATGAAAGATATCGAAGCAGGCACAAAGACCA
ACCAGCGTATCCGGACCGAGGACAAGGTGGAGCGTGCTTTCGTGGAGCCGCGGGAAATGACTTTTCTCTACCAGGAAGGC
GACAATTATATCTTCATGGACAAGGAAAACTATGAGCAACTGAGCTTGTCGCGTGATTTCCTTGAAGGGCAGTATGAATA
CCTGCTGCCGAATACAGACGTGCAAGTCAACTTCCATAACGATCGGGCAATCGGCGTGCAACTTCCTGCCAGCGTGGTGC
TCACCATCACCGACACCGAGCCCAATCTGAAAGGCGCCACCGCCACCAGTTCCTACAAACCGGCCACGACGGAAACGGGC
CTGGTAGTCATGGTCCCGCCATTCGTCCTGCAGGGGGAAAGAATCAAGGTCAATACCGATAGCGGTGAATATATCGAGCG
CATGTAG

Upstream 100 bases:

>100_bases
CAGCGCCGGCAGCTTGCTGAAAACTCAACCGGGGAAGAATTATCGGGGGTTTTTTGTAGTAAGATGCGCGCTTCTTGTTT
CAAAGGAAATCACCAGAAAT

Downstream 100 bases:

>100_bases
CCCCTCTTATGGCGCTCCAGCGAGGCTGGCAGGGAATGTAGAGGACTCGTCCCCGAACAGGCTTCGTGAAGGTATGCAAG
ATTCCGGCAGTATGCACGTT

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAKVLATEIRVGNLIEWDKRIWRVLKCYHVHVGGRGGAFMQVEMKDIEAGTKTNQRIRTEDKVERAFVEPREMTFLYQEG
DNYIFMDKENYEQLSLSRDFLEGQYEYLLPNTDVQVNFHNDRAIGVQLPASVVLTITDTEPNLKGATATSSYKPATTETG
LVVMVPPFVLQGERIKVNTDSGEYIERM

Sequences:

>Translated_188_residues
MAKVLATEIRVGNLIEWDKRIWRVLKCYHVHVGGRGGAFMQVEMKDIEAGTKTNQRIRTEDKVERAFVEPREMTFLYQEG
DNYIFMDKENYEQLSLSRDFLEGQYEYLLPNTDVQVNFHNDRAIGVQLPASVVLTITDTEPNLKGATATSSYKPATTETG
LVVMVPPFVLQGERIKVNTDSGEYIERM
>Mature_187_residues
AKVLATEIRVGNLIEWDKRIWRVLKCYHVHVGGRGGAFMQVEMKDIEAGTKTNQRIRTEDKVERAFVEPREMTFLYQEGD
NYIFMDKENYEQLSLSRDFLEGQYEYLLPNTDVQVNFHNDRAIGVQLPASVVLTITDTEPNLKGATATSSYKPATTETGL
VVMVPPFVLQGERIKVNTDSGEYIERM

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=37.7659574468085, Blast_Score=115, Evalue=1e-27,
Organism=Escherichia coli, GI87082061, Length=187, Percent_Identity=30.4812834224599, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_NITMU (Q2Y9K0)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411963.1
- ProteinModelPortal:   Q2Y9K0
- SMR:   Q2Y9K0
- STRING:   Q2Y9K0
- GeneID:   3784283
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1268
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q2Y9K0
- ProtClustDB:   PRK00529
- BioCyc:   NMUL323848:NMUL_A1268-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21514; Mature: 21383

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVLATEIRVGNLIEWDKRIWRVLKCYHVHVGGRGGAFMQVEMKDIEAGTKTNQRIRTE
CCCEEEEEECCCCCHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCCCCCCCCEECCH
DKVERAFVEPREMTFLYQEGDNYIFMDKENYEQLSLSRDFLEGQYEYLLPNTDVQVNFHN
HHHHHHHCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCCEEEEECC
DRAIGVQLPASVVLTITDTEPNLKGATATSSYKPATTETGLVVMVPPFVLQGERIKVNTD
CEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCEEEEECC
SGEYIERM
CCHHHHCC
>Mature Secondary Structure 
AKVLATEIRVGNLIEWDKRIWRVLKCYHVHVGGRGGAFMQVEMKDIEAGTKTNQRIRTE
CCEEEEEECCCCCHHHHHHHHHHHHEEEEEECCCCCEEEEEEEEECCCCCCCCCEECCH
DKVERAFVEPREMTFLYQEGDNYIFMDKENYEQLSLSRDFLEGQYEYLLPNTDVQVNFHN
HHHHHHHCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCCCEEEEECC
DRAIGVQLPASVVLTITDTEPNLKGATATSSYKPATTETGLVVMVPPFVLQGERIKVNTD
CEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCEEEEECC
SGEYIERM
CCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA