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The map label for this gene is 82702393

Identifier: 82702393

GI number: 82702393

Start: 1455922

End: 1456503

Strand: Reverse

Name: 82702393

Synonym: Nmul_A1264

Alternate gene names: NA

Gene position: 1456503-1455922 (Counterclockwise)

Preceding gene: 82702395

Following gene: 82702392

Centisome position: 45.74

GC content: 56.19

Gene sequence:

>582_bases
ATGAGCATGAGTCAGCCATCTATCGATTTTTCAGCTTCTTCCGTTGACGTTGCGCGCTCCCTCATAGGCGCCACCTTGCT
TGTAAACGGAGTTGGCGGGCGGATCGTAGAGACAGAAGCATATGACCACGATGATCCCGCCTCGCACAGCTTTTCGGGCC
CCACCAGGCGTAACCAGGTGATGTTCGGGCCTCCCTGCCATGCCTATATCTATCGCTCGTACGGCATTCACTGGTGCCTG
AATTTTGTCTGCCGGCCGGCAGGACATGGAGCTGGCGTATTGATTCGGGCGATCGAACCGCTTGTCGGCCTGGATATCAT
GCGTAAGCGGCGAGGGTTGAGCGATGAGAGACTTCTCTGTTCCGGCCCTGGCCGGGTATGCGAGGCGCTGGGCATCACGC
AGGAGTATAGCGGAATGTCCATTGATACTCCTCCGTTTCAGCTTACCCCTCCCCTTGATCCTGTTCCAGTTGTAACAGGC
CCTCGTATAGGGATTTCCAAAGCAAAGGATGTTCCCTGGCGCTTCGGACTTGCCGGTTCCCCTTTTCTGAGTCGTCCATT
CCGCCAGCCCGATATTGTTTAG

Upstream 100 bases:

>100_bases
AATGAAGCAATAAAAACCATATAGGGTAAAGCCCGGCATAGCAAGTCACTGCACGGTGCAGCAGTTGGTTTTTTGAGGCG
CTCTGTATAAAATCTGCGCC

Downstream 100 bases:

>100_bases
TTTCCTATGGCCATTTCAGGATAGAGTTCCAACCTGCGCGTAAACCTCATTCTTCGAGCAGATCGCGATCTCGGGAGTGC
CTGGCGCGTATCAGCTTCAA

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSMSQPSIDFSASSVDVARSLIGATLLVNGVGGRIVETEAYDHDDPASHSFSGPTRRNQVMFGPPCHAYIYRSYGIHWCL
NFVCRPAGHGAGVLIRAIEPLVGLDIMRKRRGLSDERLLCSGPGRVCEALGITQEYSGMSIDTPPFQLTPPLDPVPVVTG
PRIGISKAKDVPWRFGLAGSPFLSRPFRQPDIV

Sequences:

>Translated_193_residues
MSMSQPSIDFSASSVDVARSLIGATLLVNGVGGRIVETEAYDHDDPASHSFSGPTRRNQVMFGPPCHAYIYRSYGIHWCL
NFVCRPAGHGAGVLIRAIEPLVGLDIMRKRRGLSDERLLCSGPGRVCEALGITQEYSGMSIDTPPFQLTPPLDPVPVVTG
PRIGISKAKDVPWRFGLAGSPFLSRPFRQPDIV
>Mature_192_residues
SMSQPSIDFSASSVDVARSLIGATLLVNGVGGRIVETEAYDHDDPASHSFSGPTRRNQVMFGPPCHAYIYRSYGIHWCLN
FVCRPAGHGAGVLIRAIEPLVGLDIMRKRRGLSDERLLCSGPGRVCEALGITQEYSGMSIDTPPFQLTPPLDPVPVVTGP
RIGISKAKDVPWRFGLAGSPFLSRPFRQPDIV

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family

Homologues:

Organism=Homo sapiens, GI62632769, Length=198, Percent_Identity=36.3636363636364, Blast_Score=94, Evalue=5e-20,
Organism=Homo sapiens, GI62632765, Length=198, Percent_Identity=36.3636363636364, Blast_Score=94, Evalue=6e-20,
Organism=Homo sapiens, GI62632771, Length=198, Percent_Identity=36.3636363636364, Blast_Score=94, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): 3MGH_NITMU (Q2Y9K4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411959.1
- ProteinModelPortal:   Q2Y9K4
- SMR:   Q2Y9K4
- STRING:   Q2Y9K4
- GeneID:   3784279
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1264
- eggNOG:   COG2094
- HOGENOM:   HBG664239
- OMA:   LCSGPGK
- ProtClustDB:   PRK00802
- BioCyc:   NMUL323848:NMUL_A1264-MONOMER
- HAMAP:   MF_00527
- InterPro:   IPR011034
- InterPro:   IPR003180
- Gene3D:   G3DSA:3.10.300.10
- PANTHER:   PTHR10429
- TIGRFAMs:   TIGR00567

Pfam domain/function: PF02245 Pur_DNA_glyco; SSF50486 FMT_C_like

EC number: 3.2.2.-

Molecular weight: Translated: 20918; Mature: 20787

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMSQPSIDFSASSVDVARSLIGATLLVNGVGGRIVETEAYDHDDPASHSFSGPTRRNQV
CCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCEE
MFGPPCHAYIYRSYGIHWCLNFVCRPAGHGAGVLIRAIEPLVGLDIMRKRRGLSDERLLC
EECCCHHEEHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
SGPGRVCEALGITQEYSGMSIDTPPFQLTPPLDPVPVVTGPRIGISKAKDVPWRFGLAGS
CCCHHHHHHHCCCHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
PFLSRPFRQPDIV
HHHCCCCCCCCCC
>Mature Secondary Structure 
SMSQPSIDFSASSVDVARSLIGATLLVNGVGGRIVETEAYDHDDPASHSFSGPTRRNQV
CCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCEE
MFGPPCHAYIYRSYGIHWCLNFVCRPAGHGAGVLIRAIEPLVGLDIMRKRRGLSDERLLC
EECCCHHEEHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
SGPGRVCEALGITQEYSGMSIDTPPFQLTPPLDPVPVVTGPRIGISKAKDVPWRFGLAGS
CCCHHHHHHHCCCHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCC
PFLSRPFRQPDIV
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA