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The map label for this gene is bfrD [H]

Identifier: 82702389

GI number: 82702389

Start: 1449819

End: 1452086

Strand: Direct

Name: bfrD [H]

Synonym: Nmul_A1260

Alternate gene names: 82702389

Gene position: 1449819-1452086 (Clockwise)

Preceding gene: 82702387

Following gene: 82702394

Centisome position: 45.53

GC content: 54.98

Gene sequence:

>2268_bases
ATGGCAGATGCGCTCAACCGTTTTGCGCAACAGGCGGGGGCCAGCATTTCTTTTGATGCGGCTGATGTGAAAGACGTCAC
CACAAAAGGACTGAACGGGAGATTTTCGGTTCAGGAGGGGTTGGAGCATCTTTTGGCTGGTAGCGGCTTGCAGGGAGTGC
GGCAGGGAGAAGGCTACCTTGTAAGGAAGCAGCCAGAGGGAATGAGCGAGCAACCGACGGTACTGCCTCCTATCAGGGTG
ACTGCAAGTGCTGTAACCGAGCCGACGGACGGTTACATGGCGACCAAGAGTTTCAGCGCAACCAGGACAGATACGCCATT
GCGCGATGTGCCCCAGTCCATAACCGTCATGACCCAGGATATGATCCAGGATCAGACTATGCAGAGCATTACCGATGTAG
TGCGCTACGTACCAGGTGTCGTGCCCTCCCAAGGGGAAGGCAATCGTGATGCGGTGATTTTCCGCGGCAACAATACGACC
GGGGATTTTTATGTCGATGGCCTGCGCGATGACGTCCAGTATTTCCGCGATCTCTACAATATCGACCGGGTTGAAGTTCT
GAAGGGTTCCAACGGAATGATTTTTGGCCGCGGCGGCGCAGGAGGTGTAATCAATCGCGTGACCAAGGAAGCCGGTTGGA
CGCCGGTGCGGGAGATCGCGGCTCAATACGGGTCTTTCAGCCACAAGCGCATTGCTGTCGATCTGGGCCAACCCATCAAT
GATGTTGCGGCTGTTCGCCTCAACGCCATGTACGAGCATTCGAACAGTTTTCGCAATGACGTCGATCTGGAGCGCGGCGG
CGTCAATCCCACGTTCACGTTCAAACCGACTGCGCAAACCAAAGTTGTTTTCAGCGGGGAATACTTTTTTGACCGCCGTA
CGGCGGACCGGGGCATTCCTTCATTTGGGACGCGATCAGGAGTCGTGGATTCCGGCCGTCCGGCTGATACTCACCGATCC
ACGTTCTTTGGTAATGCCGCCAACAGCCCGACGCACGTCGACGCTTGGTCGCTGAATTCGCTGATCGAGCATACCTTTGA
CAACGAGGTCAAGATACGCAACCGCACCCGCTATGCCAGTTACGACAAGTTCTATCAGAACATATATGCCAACGGTGTTG
CCACGGCTGAGGATGCGACCGGCACGGTAGCGATTTCAGCCTATAACAACGCTACCCAGCGGGAGAACCTTTTTACCCAG
ACCGACCTGCTGTTCAAGCTGAACACCTGGGGCGTAAATCATGAATTCATGACGGGCGTGGAATATGGCCGCCAGATTTC
GGATAATTTCCGCAACACCGGGTTTTTCAACAACAGCACCACAAGTGTGAACGTGCCTTTCTTCAACCCCACCGCGTTTG
CGCCGGTTACCTTCAGGCAAAACGCCACGGATGCAGATAATCATGGTGTGGTGGAAGTGGTCGGCGTCTATGTTCAGGAT
CAGATTACCCTGCTTCCCCAAGTGAAGGCCGTTCTCGGCCTGCGCTACGATAATTTCGACGCCAATTTCGTGAACAATCG
CAATGGTGAGCGGTTTCACACCAATGACGGACTGCTTTCTCCCAGGGTGGGCTTGATCTACAAGCCGATCGAGCCGGTTT
CCATCTACGGCAACTACAGCCTTGCCTATGTGCCGCGGGCGGGTGACCAGTTGAGTTCTCTCAATCTGAGTAACGCCGCG
CTTAAGCCTGAGCAATTCATGAACCTGGAGTTGGGCGCCAAATGGGATATTCGGCCCGATCTTTCCTTTACCGCAGCCAT
GTATCAGCTCGAGCGCAGCAATGTCCTCGCTCCCGTTCCAAACGATCCCACAAGGTCGATGTTGGTTGATGGACAACGGG
CGCGTGGGGCAGAGGTAGGACTGATGGGTCGGATCACTCCACAGTGGAGCATGATGGGAGGATACGCCTATACCGATGCG
GAAATTACACGGACTATAACGGGTGCGAGAGCAGGGGCCGTAGTGGCCCAGGTTCCGAAGCATACTGTTTCCATGTGGAA
CCGCTATGATTTCACGCCTTTCCTCGGGCTTGGATTGGGTGTGATTCACCGAAGCAGCATGTACGCCGCGCTCGACAACA
CGGTGCTGCTGCCAGGCTTTACGCGTATGGATGCAGCGATGTTCGTGCGGCTCAACAAGGTTATCCGCGTCCAGGCAAAT
ATCGAGAATCTGGCCAATATCGACTATATCGCCTCCGCGAATAACAATAACAACATCCTGCCCGGGGCGCCGCGTATTTA
TCGCCTGACGGTGGTTGCCAATTTTTAG

Upstream 100 bases:

>100_bases
GCTGGGGCTGGCCTCGCTGGTTCTGCCCCAGATGGCGATAGCAGAGTCAGACATTGCCGCCCACGCTTCCGCTATCACCT
ACAGTATTCCTGCGGGTGCA

Downstream 100 bases:

>100_bases
ACTCCTAAGCTCGACCCAATATTCCTCTTCCCTCCTCCTCCCACTGTGGGGGAGGGGCGGGAAGAGAGGGAATGGCAGCC
TGAATGGTGAGGATAGGATG

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Virulence-associated outer membrane protein Vir-90 [H]

Number of amino acids: Translated: 755; Mature: 754

Protein sequence:

>755_residues
MADALNRFAQQAGASISFDAADVKDVTTKGLNGRFSVQEGLEHLLAGSGLQGVRQGEGYLVRKQPEGMSEQPTVLPPIRV
TASAVTEPTDGYMATKSFSATRTDTPLRDVPQSITVMTQDMIQDQTMQSITDVVRYVPGVVPSQGEGNRDAVIFRGNNTT
GDFYVDGLRDDVQYFRDLYNIDRVEVLKGSNGMIFGRGGAGGVINRVTKEAGWTPVREIAAQYGSFSHKRIAVDLGQPIN
DVAAVRLNAMYEHSNSFRNDVDLERGGVNPTFTFKPTAQTKVVFSGEYFFDRRTADRGIPSFGTRSGVVDSGRPADTHRS
TFFGNAANSPTHVDAWSLNSLIEHTFDNEVKIRNRTRYASYDKFYQNIYANGVATAEDATGTVAISAYNNATQRENLFTQ
TDLLFKLNTWGVNHEFMTGVEYGRQISDNFRNTGFFNNSTTSVNVPFFNPTAFAPVTFRQNATDADNHGVVEVVGVYVQD
QITLLPQVKAVLGLRYDNFDANFVNNRNGERFHTNDGLLSPRVGLIYKPIEPVSIYGNYSLAYVPRAGDQLSSLNLSNAA
LKPEQFMNLELGAKWDIRPDLSFTAAMYQLERSNVLAPVPNDPTRSMLVDGQRARGAEVGLMGRITPQWSMMGGYAYTDA
EITRTITGARAGAVVAQVPKHTVSMWNRYDFTPFLGLGLGVIHRSSMYAALDNTVLLPGFTRMDAAMFVRLNKVIRVQAN
IENLANIDYIASANNNNNILPGAPRIYRLTVVANF

Sequences:

>Translated_755_residues
MADALNRFAQQAGASISFDAADVKDVTTKGLNGRFSVQEGLEHLLAGSGLQGVRQGEGYLVRKQPEGMSEQPTVLPPIRV
TASAVTEPTDGYMATKSFSATRTDTPLRDVPQSITVMTQDMIQDQTMQSITDVVRYVPGVVPSQGEGNRDAVIFRGNNTT
GDFYVDGLRDDVQYFRDLYNIDRVEVLKGSNGMIFGRGGAGGVINRVTKEAGWTPVREIAAQYGSFSHKRIAVDLGQPIN
DVAAVRLNAMYEHSNSFRNDVDLERGGVNPTFTFKPTAQTKVVFSGEYFFDRRTADRGIPSFGTRSGVVDSGRPADTHRS
TFFGNAANSPTHVDAWSLNSLIEHTFDNEVKIRNRTRYASYDKFYQNIYANGVATAEDATGTVAISAYNNATQRENLFTQ
TDLLFKLNTWGVNHEFMTGVEYGRQISDNFRNTGFFNNSTTSVNVPFFNPTAFAPVTFRQNATDADNHGVVEVVGVYVQD
QITLLPQVKAVLGLRYDNFDANFVNNRNGERFHTNDGLLSPRVGLIYKPIEPVSIYGNYSLAYVPRAGDQLSSLNLSNAA
LKPEQFMNLELGAKWDIRPDLSFTAAMYQLERSNVLAPVPNDPTRSMLVDGQRARGAEVGLMGRITPQWSMMGGYAYTDA
EITRTITGARAGAVVAQVPKHTVSMWNRYDFTPFLGLGLGVIHRSSMYAALDNTVLLPGFTRMDAAMFVRLNKVIRVQAN
IENLANIDYIASANNNNNILPGAPRIYRLTVVANF
>Mature_754_residues
ADALNRFAQQAGASISFDAADVKDVTTKGLNGRFSVQEGLEHLLAGSGLQGVRQGEGYLVRKQPEGMSEQPTVLPPIRVT
ASAVTEPTDGYMATKSFSATRTDTPLRDVPQSITVMTQDMIQDQTMQSITDVVRYVPGVVPSQGEGNRDAVIFRGNNTTG
DFYVDGLRDDVQYFRDLYNIDRVEVLKGSNGMIFGRGGAGGVINRVTKEAGWTPVREIAAQYGSFSHKRIAVDLGQPIND
VAAVRLNAMYEHSNSFRNDVDLERGGVNPTFTFKPTAQTKVVFSGEYFFDRRTADRGIPSFGTRSGVVDSGRPADTHRST
FFGNAANSPTHVDAWSLNSLIEHTFDNEVKIRNRTRYASYDKFYQNIYANGVATAEDATGTVAISAYNNATQRENLFTQT
DLLFKLNTWGVNHEFMTGVEYGRQISDNFRNTGFFNNSTTSVNVPFFNPTAFAPVTFRQNATDADNHGVVEVVGVYVQDQ
ITLLPQVKAVLGLRYDNFDANFVNNRNGERFHTNDGLLSPRVGLIYKPIEPVSIYGNYSLAYVPRAGDQLSSLNLSNAAL
KPEQFMNLELGAKWDIRPDLSFTAAMYQLERSNVLAPVPNDPTRSMLVDGQRARGAEVGLMGRITPQWSMMGGYAYTDAE
ITRTITGARAGAVVAQVPKHTVSMWNRYDFTPFLGLGLGVIHRSSMYAALDNTVLLPGFTRMDAAMFVRLNKVIRVQANI
ENLANIDYIASANNNNNILPGAPRIYRLTVVANF

Specific function: Probably involved in iron transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787024, Length=706, Percent_Identity=27.3371104815864, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1786344, Length=717, Percent_Identity=27.0571827057183, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1787344, Length=752, Percent_Identity=25.6648936170213, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788478, Length=126, Percent_Identity=34.1269841269841, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1790405, Length=202, Percent_Identity=29.7029702970297, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 83203; Mature: 83072

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADALNRFAQQAGASISFDAADVKDVTTKGLNGRFSVQEGLEHLLAGSGLQGVRQGEGYL
CCHHHHHHHHHHCCEEEECCCCCHHHHHCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCEE
VRKQPEGMSEQPTVLPPIRVTASAVTEPTDGYMATKSFSATRTDTPLRDVPQSITVMTQD
EEECCCCCCCCCCCCCCCEEEHHHCCCCCCCEEEECCCCCCCCCCCHHHCCHHHHHHHHH
MIQDQTMQSITDVVRYVPGVVPSQGEGNRDAVIFRGNNTTGDFYVDGLRDDVQYFRDLYN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCHHHHHHHHHHHC
IDRVEVLKGSNGMIFGRGGAGGVINRVTKEAGWTPVREIAAQYGSFSHKRIAVDLGQPIN
CCEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCHH
DVAAVRLNAMYEHSNSFRNDVDLERGGVNPTFTFKPTAQTKVVFSGEYFFDRRTADRGIP
HHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEECCCCCEEEEECCCEEEECCHHHCCCC
SFGTRSGVVDSGRPADTHRSTFFGNAANSPTHVDAWSLNSLIEHTFDNEVKIRNRTRYAS
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECHHHHHHHHHHHCCCCEEEECCCCCCH
YDKFYQNIYANGVATAEDATGTVAISAYNNATQRENLFTQTDLLFKLNTWGVNHEFMTGV
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHCEEEEEEEEEEECCCCCHHHHHHH
EYGRQISDNFRNTGFFNNSTTSVNVPFFNPTAFAPVTFRQNATDADNHGVVEVVGVYVQD
HHHHHHHHCCCCCCCCCCCCCEEECCEECCCCCCEEEECCCCCCCCCCCEEEEEEEEECC
QITLLPQVKAVLGLRYDNFDANFVNNRNGERFHTNDGLLSPRVGLIYKPIEPVSIYGNYS
CEEHHHHHHHHHCEEECCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCEEEECCEE
LAYVPRAGDQLSSLNLSNAALKPEQFMNLELGAKWDIRPDLSFTAAMYQLERSNVLAPVP
EEEECCCCCCHHHCCCCCCCCCHHHHCEEECCCEECCCCCCHHHHHHHHHHHCCEEECCC
NDPTRSMLVDGQRARGAEVGLMGRITPQWSMMGGYAYTDAEITRTITGARAGAVVAQVPK
CCCCHHHEECCCCCCCCCEEEEECCCCCCEECCCEEECCCHHHHEECCCCCCHHHHHCCH
HTVSMWNRYDFTPFLGLGLGVIHRSSMYAALDNTVLLPGFTRMDAAMFVRLNKVIRVQAN
HHHHHHCCCCCCHHHHHHHHHHHHCHHHEECCCCEECCCCHHHHHHHHHEECEEEEEEEC
IENLANIDYIASANNNNNILPGAPRIYRLTVVANF
HHHHCCCEEEEECCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
ADALNRFAQQAGASISFDAADVKDVTTKGLNGRFSVQEGLEHLLAGSGLQGVRQGEGYL
CHHHHHHHHHHCCEEEECCCCCHHHHHCCCCCEEEHHHHHHHHHCCCCCCCCCCCCCEE
VRKQPEGMSEQPTVLPPIRVTASAVTEPTDGYMATKSFSATRTDTPLRDVPQSITVMTQD
EEECCCCCCCCCCCCCCCEEEHHHCCCCCCCEEEECCCCCCCCCCCHHHCCHHHHHHHHH
MIQDQTMQSITDVVRYVPGVVPSQGEGNRDAVIFRGNNTTGDFYVDGLRDDVQYFRDLYN
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEECCCHHHHHHHHHHHC
IDRVEVLKGSNGMIFGRGGAGGVINRVTKEAGWTPVREIAAQYGSFSHKRIAVDLGQPIN
CCEEEEEECCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCHH
DVAAVRLNAMYEHSNSFRNDVDLERGGVNPTFTFKPTAQTKVVFSGEYFFDRRTADRGIP
HHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEECCCCCEEEEECCCEEEECCHHHCCCC
SFGTRSGVVDSGRPADTHRSTFFGNAANSPTHVDAWSLNSLIEHTFDNEVKIRNRTRYAS
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECHHHHHHHHHHHCCCCEEEECCCCCCH
YDKFYQNIYANGVATAEDATGTVAISAYNNATQRENLFTQTDLLFKLNTWGVNHEFMTGV
HHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHCEEEEEEEEEEECCCCCHHHHHHH
EYGRQISDNFRNTGFFNNSTTSVNVPFFNPTAFAPVTFRQNATDADNHGVVEVVGVYVQD
HHHHHHHHCCCCCCCCCCCCCEEECCEECCCCCCEEEECCCCCCCCCCCEEEEEEEEECC
QITLLPQVKAVLGLRYDNFDANFVNNRNGERFHTNDGLLSPRVGLIYKPIEPVSIYGNYS
CEEHHHHHHHHHCEEECCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCEEEECCEE
LAYVPRAGDQLSSLNLSNAALKPEQFMNLELGAKWDIRPDLSFTAAMYQLERSNVLAPVP
EEEECCCCCCHHHCCCCCCCCCHHHHCEEECCCEECCCCCCHHHHHHHHHHHCCEEECCC
NDPTRSMLVDGQRARGAEVGLMGRITPQWSMMGGYAYTDAEITRTITGARAGAVVAQVPK
CCCCHHHEECCCCCCCCCEEEEECCCCCCEECCCEEECCCHHHHEECCCCCCHHHHHCCH
HTVSMWNRYDFTPFLGLGLGVIHRSSMYAALDNTVLLPGFTRMDAAMFVRLNKVIRVQAN
HHHHHHCCCCCCHHHHHHHHHHHHCHHHEECCCCEECCCCHHHHHHHHHEECEEEEEEEC
IENLANIDYIASANNNNNILPGAPRIYRLTVVANF
HHHHCCCEEEEECCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12910271; 10079522 [H]