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The map label for this gene is ureG

Identifier: 82702373

GI number: 82702373

Start: 1428535

End: 1429176

Strand: Direct

Name: ureG

Synonym: Nmul_A1244

Alternate gene names: 82702373

Gene position: 1428535-1429176 (Clockwise)

Preceding gene: 82702372

Following gene: 82702374

Centisome position: 44.86

GC content: 55.76

Gene sequence:

>642_bases
ATGAACAAACAATCTAATCCACTCCGTGTCGGAATCGGTGGTCCCGTAGGTTCCGGAAAAACGGCCTTGTGTGAAGCGCT
CAGCAAGAGAATGCGCGATCGGTATGAAATGGCTGTCATCACCAATGACATCTATACCAGGGAAGATATGGAAATTCTCC
TGCGTGCCGATGCGCTGCCCCCGGAGCGTCTGATGGGCGTGGAAACGGGGGGATGTCCCCATACGGCCATCAGGGAGGAT
GCTTCCATCAATCTCGAGGCCGTCGCGCGCATGACTGCCGATTTTCCGGAACTCGATCTCATTCTGATCGAATCGGGCGG
CGACAACCTTGCTTCCACCTTCAGCCCCGAACTTTCCGATCTGACGATCTATGTCATAGACGTGGCCGGGGGCGAAAAAG
TGCCGCGCAAGGGCGGGCCCGGTATTACCCGTGCTGCGTTACTCATCATCAACAAGATCGATCTTGCTCCCTACGTGGGA
GCAAATCTCGAAATCATGGCACGGGACGCCAGGAAAATGCGTGGCGAACGGCCCTTCGTGTTTACCAACCTGCATACGGG
GGAAGGAGTCGACCAGGTAATCGACTTCATCGTGAAGCAGGGACTGCTGGATGAGGTCCGGTCACAGCATCATCATGCCT
GA

Upstream 100 bases:

>100_bases
GAGTTGTCGAGCTGGGCTCCCGGCTTGTCGCTGCTGTCGATGCAACACGAGGTTCAATACAGCCGAATCTATCGATCGTA
GTTCTTGATGGGAACAGAAA

Downstream 100 bases:

>100_bases
TTTCCTTTTCCGGCAGCCTGGCAAAAGCGCGCTACTGCATCTTTCATACATAGTTTTGTAAGGGTTTCCATATATCATGG
ACTGGGCATCCCGAGTCGAC

Product: urease accessory protein UreG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MNKQSNPLRVGIGGPVGSGKTALCEALSKRMRDRYEMAVITNDIYTREDMEILLRADALPPERLMGVETGGCPHTAIRED
ASINLEAVARMTADFPELDLILIESGGDNLASTFSPELSDLTIYVIDVAGGEKVPRKGGPGITRAALLIINKIDLAPYVG
ANLEIMARDARKMRGERPFVFTNLHTGEGVDQVIDFIVKQGLLDEVRSQHHHA

Sequences:

>Translated_213_residues
MNKQSNPLRVGIGGPVGSGKTALCEALSKRMRDRYEMAVITNDIYTREDMEILLRADALPPERLMGVETGGCPHTAIRED
ASINLEAVARMTADFPELDLILIESGGDNLASTFSPELSDLTIYVIDVAGGEKVPRKGGPGITRAALLIINKIDLAPYVG
ANLEIMARDARKMRGERPFVFTNLHTGEGVDQVIDFIVKQGLLDEVRSQHHHA
>Mature_213_residues
MNKQSNPLRVGIGGPVGSGKTALCEALSKRMRDRYEMAVITNDIYTREDMEILLRADALPPERLMGVETGGCPHTAIRED
ASINLEAVARMTADFPELDLILIESGGDNLASTFSPELSDLTIYVIDVAGGEKVPRKGGPGITRAALLIINKIDLAPYVG
ANLEIMARDARKMRGERPFVFTNLHTGEGVDQVIDFIVKQGLLDEVRSQHHHA

Specific function: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by ureG

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family

Homologues:

Organism=Escherichia coli, GI1789082, Length=185, Percent_Identity=30.8108108108108, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREG_NITMU (Q2Y9M4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411939.1
- ProteinModelPortal:   Q2Y9M4
- SMR:   Q2Y9M4
- STRING:   Q2Y9M4
- GeneID:   3786020
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1244
- eggNOG:   COG0378
- HOGENOM:   HBG364734
- OMA:   LCKAMRE
- PhylomeDB:   Q2Y9M4
- ProtClustDB:   CLSK943178
- BioCyc:   NMUL323848:NMUL_A1244-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01389
- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00101

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 23234; Mature: 23234

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQSNPLRVGIGGPVGSGKTALCEALSKRMRDRYEMAVITNDIYTREDMEILLRADALP
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHEEECCCCC
PERLMGVETGGCPHTAIREDASINLEAVARMTADFPELDLILIESGGDNLASTFSPELSD
HHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCC
LTIYVIDVAGGEKVPRKGGPGITRAALLIINKIDLAPYVGANLEIMARDARKMRGERPFV
EEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCCEE
FTNLHTGEGVDQVIDFIVKQGLLDEVRSQHHHA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKQSNPLRVGIGGPVGSGKTALCEALSKRMRDRYEMAVITNDIYTREDMEILLRADALP
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHEEECCCCC
PERLMGVETGGCPHTAIREDASINLEAVARMTADFPELDLILIESGGDNLASTFSPELSD
HHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCC
LTIYVIDVAGGEKVPRKGGPGITRAALLIINKIDLAPYVGANLEIMARDARKMRGERPFV
EEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCCEE
FTNLHTGEGVDQVIDFIVKQGLLDEVRSQHHHA
EEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA