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The map label for this gene is 82702293

Identifier: 82702293

GI number: 82702293

Start: 1341928

End: 1343301

Strand: Direct

Name: 82702293

Synonym: Nmul_A1164

Alternate gene names: NA

Gene position: 1341928-1343301 (Clockwise)

Preceding gene: 82702292

Following gene: 82702294

Centisome position: 42.14

GC content: 53.86

Gene sequence:

>1374_bases
ATGGCTAATATCGATTTTGATTACCATTTGATCGATGTGCTGGAGCAGGACGCGCATACTGTTGCGGAATACAGTGCAGG
TCATGAGTTGATCCGCGCGGTACGCGAGCATGTGCAGGGGAAAAAGTTTGTCCTGATCGGTGAAGCAAGCCACGGTACAG
CCGAATTTTATCGCCTGCGTGCTGAAATTACTCAACACCTCATTGTCGAGGACGGATTCGACGCTGTTGCGGTCGAGGCG
GACTGGCCGGATGCCTATCGGGTCAACCGTTTTGTTGCCGACCGTTCGGAAGATAAGGATGCGGATGCAGCATTGTCCAA
TTTCGAACGGTTTCCCACGTGGATGTGGAGGAATACCGAGGTATTCGCTTTCATCACATGGTTGCGCAACTATAACCAGG
AGACGGGGAGACACAAGCGCGAGCAACAGGAACCGGTGGGGTTTTATGGACTCGATTTATACAGTATGACAACCTCGATG
CGGGCAGTGCTGGCATATCTGGAAAAGATCGATCCGGAAGAAGCTCGCGCCGCCCGGGCACGCTACCGTTGCTTTGGCCA
ATTCATCGAAAATCCGCAGGCGTATGGTTATGCCATTGCGTCCGGGCGGTGGGATTCGTGCGAACAGGAAGTGATCGCAC
AGCTTATGCAGCTTCAGCGAAAAGGACGGCTTTACGTTGAAAAGGATGGGGTTTTTGCCGGAAATGAATATTTCTCGGCG
CAGCAGAATGCCGAGCTGGTAAAAAATGCGGAGGAGTATTATCGCGCCATGTTCAGGGGAAGGCCCAATACATGGAACCT
GAGAGACCGGCACATGTTCGAGACGCTCGAAAAGCTCGCCAGCCATCTGGAAGACCGACTGAAGCGGGAAGCGCGCATCA
TTGTCTGGGCCCACAATTCTCATCTGGGCAATGCGGCGGCCACCGAAATGGGGCGGCGGGGCGAATTCAACATCGGCCAG
CTCGTTACCGAGAAATATCCGGATAAGTCATTCCGCATCGGATTTTCGACGAGCCGGGGCAGCGTGACTGCGGCAACTGA
TTGGGATGGACCCGCCGAAACGAAAACCGTTCGCGAACCGGTTGCAGGCAGTTACGAAGAAATTTTTTCGCAACTGGCCA
AGAAACGTTTCTTTTTCGATCTCACTACTGACGGCGAAGCCATGGAGTTTCTACGGGAGGAGCGGCTGCAACGGGCTATC
GGAGTGATCTACCGGCCTGAAACCGAGAGGATGAGCCATTACTTCTATGCCTGTCTCCCGTGGCAATTCGATTTCATGAT
TCATATCGACAAGACGGAAGCGCTACAACCGTTGCCCGCATTCGTCCGCCGCCGGGCGGGTGAAATGGATGAGACCTATC
CTTCAGGCTTGTAG

Upstream 100 bases:

>100_bases
AACCCTTCGGCGAACAACCGAAACTCCAAAGAGAGCGACTTAAGGGGAGACGGAGGGAATTGCAGGATTCCGTCGCCTGA
GGCTCGAGGAGGATTTCATT

Downstream 100 bases:

>100_bases
GAGACCGCGTTTCTCGATTCTCAAGGTGGCGGTGCAGAAAGCGAAGCGCACTGCCAGTCTGGATATGCCGCATATCTACT
GAACGGAGATTCGAAAATGA

Product: erythromycin esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MANIDFDYHLIDVLEQDAHTVAEYSAGHELIRAVREHVQGKKFVLIGEASHGTAEFYRLRAEITQHLIVEDGFDAVAVEA
DWPDAYRVNRFVADRSEDKDADAALSNFERFPTWMWRNTEVFAFITWLRNYNQETGRHKREQQEPVGFYGLDLYSMTTSM
RAVLAYLEKIDPEEARAARARYRCFGQFIENPQAYGYAIASGRWDSCEQEVIAQLMQLQRKGRLYVEKDGVFAGNEYFSA
QQNAELVKNAEEYYRAMFRGRPNTWNLRDRHMFETLEKLASHLEDRLKREARIIVWAHNSHLGNAAATEMGRRGEFNIGQ
LVTEKYPDKSFRIGFSTSRGSVTAATDWDGPAETKTVREPVAGSYEEIFSQLAKKRFFFDLTTDGEAMEFLREERLQRAI
GVIYRPETERMSHYFYACLPWQFDFMIHIDKTEALQPLPAFVRRRAGEMDETYPSGL

Sequences:

>Translated_457_residues
MANIDFDYHLIDVLEQDAHTVAEYSAGHELIRAVREHVQGKKFVLIGEASHGTAEFYRLRAEITQHLIVEDGFDAVAVEA
DWPDAYRVNRFVADRSEDKDADAALSNFERFPTWMWRNTEVFAFITWLRNYNQETGRHKREQQEPVGFYGLDLYSMTTSM
RAVLAYLEKIDPEEARAARARYRCFGQFIENPQAYGYAIASGRWDSCEQEVIAQLMQLQRKGRLYVEKDGVFAGNEYFSA
QQNAELVKNAEEYYRAMFRGRPNTWNLRDRHMFETLEKLASHLEDRLKREARIIVWAHNSHLGNAAATEMGRRGEFNIGQ
LVTEKYPDKSFRIGFSTSRGSVTAATDWDGPAETKTVREPVAGSYEEIFSQLAKKRFFFDLTTDGEAMEFLREERLQRAI
GVIYRPETERMSHYFYACLPWQFDFMIHIDKTEALQPLPAFVRRRAGEMDETYPSGL
>Mature_456_residues
ANIDFDYHLIDVLEQDAHTVAEYSAGHELIRAVREHVQGKKFVLIGEASHGTAEFYRLRAEITQHLIVEDGFDAVAVEAD
WPDAYRVNRFVADRSEDKDADAALSNFERFPTWMWRNTEVFAFITWLRNYNQETGRHKREQQEPVGFYGLDLYSMTTSMR
AVLAYLEKIDPEEARAARARYRCFGQFIENPQAYGYAIASGRWDSCEQEVIAQLMQLQRKGRLYVEKDGVFAGNEYFSAQ
QNAELVKNAEEYYRAMFRGRPNTWNLRDRHMFETLEKLASHLEDRLKREARIIVWAHNSHLGNAAATEMGRRGEFNIGQL
VTEKYPDKSFRIGFSTSRGSVTAATDWDGPAETKTVREPVAGSYEEIFSQLAKKRFFFDLTTDGEAMEFLREERLQRAIG
VIYRPETERMSHYFYACLPWQFDFMIHIDKTEALQPLPAFVRRRAGEMDETYPSGL

Specific function: Unknown

COG id: COG2312

COG function: function code R; Erythromycin esterase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007815
- InterPro:   IPR000836 [H]

Pfam domain/function: PF05139 Erythro_esteras; PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 53110; Mature: 52979

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIDFDYHLIDVLEQDAHTVAEYSAGHELIRAVREHVQGKKFVLIGEASHGTAEFYRLR
CCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
AEITQHLIVEDGFDAVAVEADWPDAYRVNRFVADRSEDKDADAALSNFERFPTWMWRNTE
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCCCH
VFAFITWLRNYNQETGRHKREQQEPVGFYGLDLYSMTTSMRAVLAYLEKIDPEEARAARA
HHHHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RYRCFGQFIENPQAYGYAIASGRWDSCEQEVIAQLMQLQRKGRLYVEKDGVFAGNEYFSA
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCEEECCHHHCC
QQNAELVKNAEEYYRAMFRGRPNTWNLRDRHMFETLEKLASHLEDRLKREARIIVWAHNS
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
HLGNAAATEMGRRGEFNIGQLVTEKYPDKSFRIGFSTSRGSVTAATDWDGPAETKTVREP
CCCCHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHHC
VAGSYEEIFSQLAKKRFFFDLTTDGEAMEFLREERLQRAIGVIYRPETERMSHYFYACLP
CCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHCEEECCCHHHHHHEEEEEEC
WQFDFMIHIDKTEALQPLPAFVRRRAGEMDETYPSGL
EEEEEEEEECCHHHCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ANIDFDYHLIDVLEQDAHTVAEYSAGHELIRAVREHVQGKKFVLIGEASHGTAEFYRLR
CCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
AEITQHLIVEDGFDAVAVEADWPDAYRVNRFVADRSEDKDADAALSNFERFPTWMWRNTE
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCCCH
VFAFITWLRNYNQETGRHKREQQEPVGFYGLDLYSMTTSMRAVLAYLEKIDPEEARAARA
HHHHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RYRCFGQFIENPQAYGYAIASGRWDSCEQEVIAQLMQLQRKGRLYVEKDGVFAGNEYFSA
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCEEECCHHHCC
QQNAELVKNAEEYYRAMFRGRPNTWNLRDRHMFETLEKLASHLEDRLKREARIIVWAHNS
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
HLGNAAATEMGRRGEFNIGQLVTEKYPDKSFRIGFSTSRGSVTAATDWDGPAETKTVREP
CCCCHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCCCCCHHHHHC
VAGSYEEIFSQLAKKRFFFDLTTDGEAMEFLREERLQRAIGVIYRPETERMSHYFYACLP
CCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHCEEECCCHHHHHHEEEEEEC
WQFDFMIHIDKTEALQPLPAFVRRRAGEMDETYPSGL
EEEEEEEEECCHHHCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]