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The map label for this gene is pntB [H]

Identifier: 82702282

GI number: 82702282

Start: 1329683

End: 1331062

Strand: Direct

Name: pntB [H]

Synonym: Nmul_A1153

Alternate gene names: 82702282

Gene position: 1329683-1331062 (Clockwise)

Preceding gene: 82702281

Following gene: 82702283

Centisome position: 41.76

GC content: 57.9

Gene sequence:

>1380_bases
ATGTCGGCAAATACGGTCGCTCTCGCGTATCTTATCGCCTCGGTCTTCTTCATCCTGGCGTTAAAAGGTTTAAGCTCGCC
GCTCTCCGCCCGACGCGGGAATCTGTTCGGGATCGTCGGAATGGTAATTGCGGTCATTACCACGCTTACCATCACCAAGA
ACTGGGCGTTGATCATTGTCTGCATCGCGCTGGGAGGGGCCATCGGCGCGGTGGTGGCCCGGCGTGTGCAGATGACCGCG
ATGCCCGAACTGGTTGCGTTCATGCACTCCCTCGTCGGTCTGGCGGCGGTATTCATCGCCATCGCCGCAGTCAATAATCC
CGCTTCCTTTGGTTTGCCCGAGACATTGCCGATGGGCAGCAAGCTGGAATTGTTTCTTGGCACATTCATCGGGGCCATGA
CCTGGTCGGGTTCGGTGATCGCCTTCCTCAAATTGTCAGGCCGGATGAGTGGCGCACCCATCACTTTCGGCGGTCAGCAT
AAGGTCAATCTGGCCCTGGCGATCATCATGATTGGATTCGGCCTGGGGTTTTTCTTCAGCGCCACCACGAACTGGACTGC
CTTCGCCGCCATGACCGCGGTTGCGTTCGTGCTCGGCTTTCTCATCATCATTCCGATTGGCGGCGCTGACATGCCCGTGG
TCATTTCCATGCTCAATTCCTACTCCGGGTGGGCCGCAGCCGGTATCGGGTTCTCGCTTGGCAATCCCATGCTGATCATC
GCGGGATCACTGGTGGGCAGTTCGGGTGCGATCCTGTCCTATATCATGTGCAAGGCGATGAACCGTCCCTTCCTCTCCGT
CATACTGGGTGGGTTCGGAAGTGAGGGGGGGGCCGCCGCGGCAGGAGATGGGACGCAAAAGACCTATCGCAGCGGCAGTG
CGGATGATGCTGCTTTCATCATGGGAAATGCCGATAGCGTCATCATCGTGCCGGGCTACGGCCTGGCTGTGGCCAGGGCG
CAGCATGCGGTGAAGGAACTGGCGGAAATGCTGCACAAGAAAGGCGTGAACGTGCGTTTTGCCATCCATCCTGTTGCGGG
GCGCATGCCGGGGCACATGAACGTGCTGCTCGCCGAAGCCGAGATACCGTATGAGCAGGTGCTGGAGATGGATGAGATCA
ACAGCGATTTTTCCAATACCGACGTGGTGCTTGTGCTTGGCGCAAACGACGTGGTGAATCCGGCGGCAAATGTGCCCGGT
AGTCCGATCTACGGCATGCCCATTCTGGATGCGCATAAAGCGCGTACGGTAATGGTGGTCAAACGCAGCATGGCAGCGGG
TTATGCTGGCCTGGACAACGATCTCTTCTACATGGACAAGACCATGATGATATTCGGGGATGCCAAGAAGGTCGTCGAGG
ATATGGTCAAGGCCTTGTAA

Upstream 100 bases:

>100_bases
CGCGGTAACCCTGGCCGCGATCAATGTATTCGGGGGATTTCTCGTTACCCAGCGGATGCTGGAAATGTTCAGAAAAAAAG
ATAAAAAAGGAAGCTAGTCA

Downstream 100 bases:

>100_bases
CATTGAACATCGCCAGCAGCATCGGATGATGCCAGATGTAAGGACGCAGTGAGCGCAATCAAGGGTTTTTCTGAAGAACT
GTTCACTGCGGACGGTCATA

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MSANTVALAYLIASVFFILALKGLSSPLSARRGNLFGIVGMVIAVITTLTITKNWALIIVCIALGGAIGAVVARRVQMTA
MPELVAFMHSLVGLAAVFIAIAAVNNPASFGLPETLPMGSKLELFLGTFIGAMTWSGSVIAFLKLSGRMSGAPITFGGQH
KVNLALAIIMIGFGLGFFFSATTNWTAFAAMTAVAFVLGFLIIIPIGGADMPVVISMLNSYSGWAAAGIGFSLGNPMLII
AGSLVGSSGAILSYIMCKAMNRPFLSVILGGFGSEGGAAAAGDGTQKTYRSGSADDAAFIMGNADSVIIVPGYGLAVARA
QHAVKELAEMLHKKGVNVRFAIHPVAGRMPGHMNVLLAEAEIPYEQVLEMDEINSDFSNTDVVLVLGANDVVNPAANVPG
SPIYGMPILDAHKARTVMVVKRSMAAGYAGLDNDLFYMDKTMMIFGDAKKVVEDMVKAL

Sequences:

>Translated_459_residues
MSANTVALAYLIASVFFILALKGLSSPLSARRGNLFGIVGMVIAVITTLTITKNWALIIVCIALGGAIGAVVARRVQMTA
MPELVAFMHSLVGLAAVFIAIAAVNNPASFGLPETLPMGSKLELFLGTFIGAMTWSGSVIAFLKLSGRMSGAPITFGGQH
KVNLALAIIMIGFGLGFFFSATTNWTAFAAMTAVAFVLGFLIIIPIGGADMPVVISMLNSYSGWAAAGIGFSLGNPMLII
AGSLVGSSGAILSYIMCKAMNRPFLSVILGGFGSEGGAAAAGDGTQKTYRSGSADDAAFIMGNADSVIIVPGYGLAVARA
QHAVKELAEMLHKKGVNVRFAIHPVAGRMPGHMNVLLAEAEIPYEQVLEMDEINSDFSNTDVVLVLGANDVVNPAANVPG
SPIYGMPILDAHKARTVMVVKRSMAAGYAGLDNDLFYMDKTMMIFGDAKKVVEDMVKAL
>Mature_458_residues
SANTVALAYLIASVFFILALKGLSSPLSARRGNLFGIVGMVIAVITTLTITKNWALIIVCIALGGAIGAVVARRVQMTAM
PELVAFMHSLVGLAAVFIAIAAVNNPASFGLPETLPMGSKLELFLGTFIGAMTWSGSVIAFLKLSGRMSGAPITFGGQHK
VNLALAIIMIGFGLGFFFSATTNWTAFAAMTAVAFVLGFLIIIPIGGADMPVVISMLNSYSGWAAAGIGFSLGNPMLIIA
GSLVGSSGAILSYIMCKAMNRPFLSVILGGFGSEGGAAAAGDGTQKTYRSGSADDAAFIMGNADSVIIVPGYGLAVARAQ
HAVKELAEMLHKKGVNVRFAIHPVAGRMPGHMNVLLAEAEIPYEQVLEMDEINSDFSNTDVVLVLGANDVVNPAANVPGS
PIYGMPILDAHKARTVMVVKRSMAAGYAGLDNDLFYMDKTMMIFGDAKKVVEDMVKAL

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=459, Percent_Identity=46.4052287581699, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI122939153, Length=459, Percent_Identity=46.4052287581699, Blast_Score=377, Evalue=1e-104,
Organism=Escherichia coli, GI1787886, Length=467, Percent_Identity=53.3190578158458, Blast_Score=460, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17550456, Length=463, Percent_Identity=43.6285097192225, Blast_Score=343, Evalue=9e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 47826; Mature: 47695

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSANTVALAYLIASVFFILALKGLSSPLSARRGNLFGIVGMVIAVITTLTITKNWALIIV
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
CIALGGAIGAVVARRVQMTAMPELVAFMHSLVGLAAVFIAIAAVNNPASFGLPETLPMGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
KLELFLGTFIGAMTWSGSVIAFLKLSGRMSGAPITFGGQHKVNLALAIIMIGFGLGFFFS
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHC
ATTNWTAFAAMTAVAFVLGFLIIIPIGGADMPVVISMLNSYSGWAAAGIGFSLGNPMLII
CCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEE
AGSLVGSSGAILSYIMCKAMNRPFLSVILGGFGSEGGAAAAGDGTQKTYRSGSADDAAFI
EECCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCEEE
MGNADSVIIVPGYGLAVARAQHAVKELAEMLHKKGVNVRFAIHPVAGRMPGHMNVLLAEA
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEC
EIPYEQVLEMDEINSDFSNTDVVLVLGANDVVNPAANVPGSPIYGMPILDAHKARTVMVV
CCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
KRSMAAGYAGLDNDLFYMDKTMMIFGDAKKVVEDMVKAL
HHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHC
>Mature Secondary Structure 
SANTVALAYLIASVFFILALKGLSSPLSARRGNLFGIVGMVIAVITTLTITKNWALIIV
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
CIALGGAIGAVVARRVQMTAMPELVAFMHSLVGLAAVFIAIAAVNNPASFGLPETLPMGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
KLELFLGTFIGAMTWSGSVIAFLKLSGRMSGAPITFGGQHKVNLALAIIMIGFGLGFFFS
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHC
ATTNWTAFAAMTAVAFVLGFLIIIPIGGADMPVVISMLNSYSGWAAAGIGFSLGNPMLII
CCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHCCCCCEECCCCCCCCCCEEEE
AGSLVGSSGAILSYIMCKAMNRPFLSVILGGFGSEGGAAAAGDGTQKTYRSGSADDAAFI
EECCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCEEE
MGNADSVIIVPGYGLAVARAQHAVKELAEMLHKKGVNVRFAIHPVAGRMPGHMNVLLAEA
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEC
EIPYEQVLEMDEINSDFSNTDVVLVLGANDVVNPAANVPGSPIYGMPILDAHKARTVMVV
CCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEE
KRSMAAGYAGLDNDLFYMDKTMMIFGDAKKVVEDMVKAL
HHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]