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The map label for this gene is fabD [H]

Identifier: 82702202

GI number: 82702202

Start: 1239411

End: 1240361

Strand: Direct

Name: fabD [H]

Synonym: Nmul_A1073

Alternate gene names: 82702202

Gene position: 1239411-1240361 (Clockwise)

Preceding gene: 82702201

Following gene: 82702203

Centisome position: 38.92

GC content: 54.47

Gene sequence:

>951_bases
ATGAGCGCACAGGTTAAATTTGCATGTGTTTTCCCGGGACAGGGGTCTCAGTCCATAGGGATGATGGCCGGATATGATAG
CTTTCCGGTGGTACGGCAGACTTTTGCTGAAGCATCCGATGTGCTGAAGCTGGATTTGTGGGGGATGGTGTGTGACGGTC
CGGCCGAAACCCTCAACCTGACCGTTAATACTCAGCCGCTGATGCTGACTGCCGGAGTAGCGATTTACCGGGCGTGGCAG
ACCTTGGGTGGAGTGAGGCCCTCTTTCGTGGCCGGCCATAGTCTCGGGGAATATACGGCGCTGGTAGCTTCTGAGGCATT
GTCTTTTGCTGATGCCTTGCCATTGGTACGCTTTCGTGCGGAGATAATGCAGCAGGCTGTACCTGAAGGAGTGGGTGCGA
TGGCGGCGATTCTCGGACTCGATGATGACGTTGTACGGTCGATCTGTCAGGAGGTTACAGAAGCATCGAATGGGGAGTCG
CTGGAACCTGCAAACTTCAACTCACCCGGCCAAGTCGTGGTTGCGGGGCACAAAAACGCGGTGGTTCGCGGCATGGAAGC
GGCAAGGTCTAAAGGCGCAAAGCGGACCGTCATATTGCCCATGAGCATTCCTTCGCACTGCTCCCTGATGAAACCCGCAG
CGGAAAAAATGCGCCAACAACTGGCACAAGTAACACTTCGTTCACCCAAAATCCCGCTATTGCACAATGCGGATGTGGAA
CAGCACGAGGATATTGAGAGCATCAAGGAAATTCTGGTCCGGCAGTTGTTTAATCCTGTCCGCTGGACGGAAATCATTCG
TTTTATTTCCGGAGCCGGAATCCATCATGTGGTGGAATGCGGCCCCGGCAAAGTCCTGTCAGGACTCAACAAACGTATAG
ATGCGAATTTGCAGAGCCTGGCATTGACTGACGAGGCGGCGCTGGGTCATGCAGCGGCTTTGGCAGGATAA

Upstream 100 bases:

>100_bases
TTCCCTTTTCAGCCGGATTTTAACAACTTTTTTTCTTCGGCTCGAAGGTTTTTCGCTACCTGCCGCAGATGGAACTGTCG
AAGGATTGGTACTGATACTG

Downstream 100 bases:

>100_bases
AGGTCAGGCGGGCATATCCAGCAGGGCCGCATTGCTCATCATTGAACGACGTACTGGAAGATCATGCTGCAAAATCAGAT
AGCACTTGTAACCGGCGCCA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSAQVKFACVFPGQGSQSIGMMAGYDSFPVVRQTFAEASDVLKLDLWGMVCDGPAETLNLTVNTQPLMLTAGVAIYRAWQ
TLGGVRPSFVAGHSLGEYTALVASEALSFADALPLVRFRAEIMQQAVPEGVGAMAAILGLDDDVVRSICQEVTEASNGES
LEPANFNSPGQVVVAGHKNAVVRGMEAARSKGAKRTVILPMSIPSHCSLMKPAAEKMRQQLAQVTLRSPKIPLLHNADVE
QHEDIESIKEILVRQLFNPVRWTEIIRFISGAGIHHVVECGPGKVLSGLNKRIDANLQSLALTDEAALGHAAALAG

Sequences:

>Translated_316_residues
MSAQVKFACVFPGQGSQSIGMMAGYDSFPVVRQTFAEASDVLKLDLWGMVCDGPAETLNLTVNTQPLMLTAGVAIYRAWQ
TLGGVRPSFVAGHSLGEYTALVASEALSFADALPLVRFRAEIMQQAVPEGVGAMAAILGLDDDVVRSICQEVTEASNGES
LEPANFNSPGQVVVAGHKNAVVRGMEAARSKGAKRTVILPMSIPSHCSLMKPAAEKMRQQLAQVTLRSPKIPLLHNADVE
QHEDIESIKEILVRQLFNPVRWTEIIRFISGAGIHHVVECGPGKVLSGLNKRIDANLQSLALTDEAALGHAAALAG
>Mature_315_residues
SAQVKFACVFPGQGSQSIGMMAGYDSFPVVRQTFAEASDVLKLDLWGMVCDGPAETLNLTVNTQPLMLTAGVAIYRAWQT
LGGVRPSFVAGHSLGEYTALVASEALSFADALPLVRFRAEIMQQAVPEGVGAMAAILGLDDDVVRSICQEVTEASNGESL
EPANFNSPGQVVVAGHKNAVVRGMEAARSKGAKRTVILPMSIPSHCSLMKPAAEKMRQQLAQVTLRSPKIPLLHNADVEQ
HEDIESIKEILVRQLFNPVRWTEIIRFISGAGIHHVVECGPGKVLSGLNKRIDANLQSLALTDEAALGHAAALAG

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=309, Percent_Identity=34.3042071197411, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI27477045, Length=108, Percent_Identity=41.6666666666667, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1787334, Length=310, Percent_Identity=52.258064516129, Blast_Score=324, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI71984332, Length=268, Percent_Identity=29.1044776119403, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17550940, Length=298, Percent_Identity=27.1812080536913, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24665753, Length=302, Percent_Identity=33.4437086092715, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33674; Mature: 33543

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00936 RIBOSOMAL_L35

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQVKFACVFPGQGSQSIGMMAGYDSFPVVRQTFAEASDVLKLDLWGMVCDGPAETLNL
CCCCEEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHHEEEEEEEEEEECCCCCEEEE
TVNTQPLMLTAGVAIYRAWQTLGGVRPSFVAGHSLGEYTALVASEALSFADALPLVRFRA
EECCCCEEEHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EIMQQAVPEGVGAMAAILGLDDDVVRSICQEVTEASNGESLEPANFNSPGQVVVAGHKNA
HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCH
VVRGMEAARSKGAKRTVILPMSIPSHCSLMKPAAEKMRQQLAQVTLRSPKIPLLHNADVE
HHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCH
QHEDIESIKEILVRQLFNPVRWTEIIRFISGAGIHHVVECGPGKVLSGLNKRIDANLQSL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCHHHH
ALTDEAALGHAAALAG
EECHHHHHHHHHHHCC
>Mature Secondary Structure 
SAQVKFACVFPGQGSQSIGMMAGYDSFPVVRQTFAEASDVLKLDLWGMVCDGPAETLNL
CCCEEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHHHEEEEEEEEEEECCCCCEEEE
TVNTQPLMLTAGVAIYRAWQTLGGVRPSFVAGHSLGEYTALVASEALSFADALPLVRFRA
EECCCCEEEHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EIMQQAVPEGVGAMAAILGLDDDVVRSICQEVTEASNGESLEPANFNSPGQVVVAGHKNA
HHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCH
VVRGMEAARSKGAKRTVILPMSIPSHCSLMKPAAEKMRQQLAQVTLRSPKIPLLHNADVE
HHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCH
QHEDIESIKEILVRQLFNPVRWTEIIRFISGAGIHHVVECGPGKVLSGLNKRIDANLQSL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCHHHH
ALTDEAALGHAAALAG
EECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]