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The map label for this gene is sasA [H]

Identifier: 82702129

GI number: 82702129

Start: 1160959

End: 1162116

Strand: Reverse

Name: sasA [H]

Synonym: Nmul_A1000

Alternate gene names: 82702129

Gene position: 1162116-1160959 (Counterclockwise)

Preceding gene: 82702130

Following gene: 82702126

Centisome position: 36.5

GC content: 48.7

Gene sequence:

>1158_bases
ATGACTCTGGCAAGCGACCAAAATATCAATCCTGAGAAACTTTCCGCAACCGCTCGAAGAATGCTCGAGCTTCGAGATGA
AGTACTTTCGGAATGGATGAAAAGGGTTCGAAACAGCATCAAGGAAGCCGAGCATTTACCCAATCCAATAATCATCAATA
CCTTTCCCGCCCTGTACGATAACCTTGCCGAAGCTATTACGCCTGATTATCCAAGAGCAACAGGAAATGAGGGTACTACG
GTGGCGGCGGAGCACGGTGGGGAGCGAGCGCGCCTTACAAGCTATAACGCGCACTCGGTAATCGCGGAATATCAGCAACT
GCGGTGGACAATCTTTGATGTTCTAAAGATGAATGACGTACGCCTCAATGACCGTGAAATTTACATTATCAATGCCTCTA
TCGATGGATCAATCCGTGAGGCTGTCAACGCCTTCGCCTTGACCCAGGCAGCGCTCCAGGAAAGATTTGTTGCAACACTT
GCTCACGACCTGAGAAATCCATTATCGAATGCCCATCTTGCCGCCCAGTTGATCAAATCCACGTCCGATTTGAACAAGAT
AAAGGAATTTGCGGAAGGAATCATGAACAACCTGAGTCGAATGGATGGAATGATTCGCGATTTGCTCGACTCGATAAAAT
TCCACATGGGAGAACAATTACACCTGCGGCTCAAGGAATTCGACATACAGGAAGTCATGAAGGAAGTACTCGACAGCTTC
ACCGCCATTCATGGGGCACGCTTCCGTCTGATCGGCACTTCTATCACAGGATGGTGGGACCGGGAGGCAATCAAACGGGC
GGTGGAAAATATTATTGGAAATGCAGTGAAATATGGCTCTGCCGATACGCCTGTTCGAATCAAGATTGCTTCACAAAACG
AGCGCATGCTACTGTCTGTGCATAACGAAGGGGAATTCATTCCACCTGAACAAATCGAGAGTATATTTCAAATATTCGGA
AGAGCAGAGGCCGCAAAAAAGGGAAACAAGGAAGGCTGGGGTATTGGCTTGCCGTATGTGCGAAGTGTTGCGGAAACCCA
TGGTGGCAGTGTCGCGGTCGATAGCTCACCTTATCGCGGCACAACCTTCACGATAGATATTCCGGTGGATGCAAGACCTT
ATCAAGGTGCCTTGCAACCTTCCCGGAAGCCGGAATGA

Upstream 100 bases:

>100_bases
CTAAATGCTCCGATCCGTCACCCACCAACTCTTCGTGGCTATCTTCCCAAGGCTTAAATCATATTGCTCCTTTCCTCATC
AATAAAAAAGGGCGTTTATC

Downstream 100 bases:

>100_bases
CTTGTAATAATTTCGATATCACTCTGATCGTTTCCCCTATTTCAAGGTGATTTCCCGACTGACCCTTCGACAAGCATTTC
CTGAGCTCGTCGAAGGGCTC

Product: histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTLASDQNINPEKLSATARRMLELRDEVLSEWMKRVRNSIKEAEHLPNPIIINTFPALYDNLAEAITPDYPRATGNEGTT
VAAEHGGERARLTSYNAHSVIAEYQQLRWTIFDVLKMNDVRLNDREIYIINASIDGSIREAVNAFALTQAALQERFVATL
AHDLRNPLSNAHLAAQLIKSTSDLNKIKEFAEGIMNNLSRMDGMIRDLLDSIKFHMGEQLHLRLKEFDIQEVMKEVLDSF
TAIHGARFRLIGTSITGWWDREAIKRAVENIIGNAVKYGSADTPVRIKIASQNERMLLSVHNEGEFIPPEQIESIFQIFG
RAEAAKKGNKEGWGIGLPYVRSVAETHGGSVAVDSSPYRGTTFTIDIPVDARPYQGALQPSRKPE

Sequences:

>Translated_385_residues
MTLASDQNINPEKLSATARRMLELRDEVLSEWMKRVRNSIKEAEHLPNPIIINTFPALYDNLAEAITPDYPRATGNEGTT
VAAEHGGERARLTSYNAHSVIAEYQQLRWTIFDVLKMNDVRLNDREIYIINASIDGSIREAVNAFALTQAALQERFVATL
AHDLRNPLSNAHLAAQLIKSTSDLNKIKEFAEGIMNNLSRMDGMIRDLLDSIKFHMGEQLHLRLKEFDIQEVMKEVLDSF
TAIHGARFRLIGTSITGWWDREAIKRAVENIIGNAVKYGSADTPVRIKIASQNERMLLSVHNEGEFIPPEQIESIFQIFG
RAEAAKKGNKEGWGIGLPYVRSVAETHGGSVAVDSSPYRGTTFTIDIPVDARPYQGALQPSRKPE
>Mature_384_residues
TLASDQNINPEKLSATARRMLELRDEVLSEWMKRVRNSIKEAEHLPNPIIINTFPALYDNLAEAITPDYPRATGNEGTTV
AAEHGGERARLTSYNAHSVIAEYQQLRWTIFDVLKMNDVRLNDREIYIINASIDGSIREAVNAFALTQAALQERFVATLA
HDLRNPLSNAHLAAQLIKSTSDLNKIKEFAEGIMNNLSRMDGMIRDLLDSIKFHMGEQLHLRLKEFDIQEVMKEVLDSFT
AIHGARFRLIGTSITGWWDREAIKRAVENIIGNAVKYGSADTPVRIKIASQNERMLLSVHNEGEFIPPEQIESIFQIFGR
AEAAKKGNKEGWGIGLPYVRSVAETHGGSVAVDSSPYRGTTFTIDIPVDARPYQGALQPSRKPE

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=29.7297297297297, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=29.004329004329, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=26.6393442622951, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788713, Length=314, Percent_Identity=23.5668789808917, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=25.6521739130435, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=224, Percent_Identity=27.2321428571429, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=24.7747747747748, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789149, Length=275, Percent_Identity=25.0909090909091, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=20.4081632653061, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081816, Length=223, Percent_Identity=22.4215246636771, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=24.4343891402715, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786600, Length=219, Percent_Identity=22.8310502283105, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=24.5535714285714, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 43150; Mature: 43018

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLASDQNINPEKLSATARRMLELRDEVLSEWMKRVRNSIKEAEHLPNPIIINTFPALYD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHH
NLAEAITPDYPRATGNEGTTVAAEHGGERARLTSYNAHSVIAEYQQLRWTIFDVLKMNDV
HHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCE
RLNDREIYIINASIDGSIREAVNAFALTQAALQERFVATLAHDLRNPLSNAHLAAQLIKS
EECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSDLNKIKEFAEGIMNNLSRMDGMIRDLLDSIKFHMGEQLHLRLKEFDIQEVMKEVLDSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH
TAIHGARFRLIGTSITGWWDREAIKRAVENIIGNAVKYGSADTPVRIKIASQNERMLLSV
HHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEE
HNEGEFIPPEQIESIFQIFGRAEAAKKGNKEGWGIGLPYVRSVAETHGGSVAVDSSPYRG
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCC
TTFTIDIPVDARPYQGALQPSRKPE
CEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLASDQNINPEKLSATARRMLELRDEVLSEWMKRVRNSIKEAEHLPNPIIINTFPALYD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHH
NLAEAITPDYPRATGNEGTTVAAEHGGERARLTSYNAHSVIAEYQQLRWTIFDVLKMNDV
HHHHHHCCCCCCCCCCCCCEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCE
RLNDREIYIINASIDGSIREAVNAFALTQAALQERFVATLAHDLRNPLSNAHLAAQLIKS
EECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSDLNKIKEFAEGIMNNLSRMDGMIRDLLDSIKFHMGEQLHLRLKEFDIQEVMKEVLDSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH
TAIHGARFRLIGTSITGWWDREAIKRAVENIIGNAVKYGSADTPVRIKIASQNERMLLSV
HHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEE
HNEGEFIPPEQIESIFQIFGRAEAAKKGNKEGWGIGLPYVRSVAETHGGSVAVDSSPYRG
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEECCCCCCC
TTFTIDIPVDARPYQGALQPSRKPE
CEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA