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The map label for this gene is macB [H]

Identifier: 82702083

GI number: 82702083

Start: 1106247

End: 1107446

Strand: Direct

Name: macB [H]

Synonym: Nmul_A0954

Alternate gene names: 82702083

Gene position: 1106247-1107446 (Clockwise)

Preceding gene: 82702082

Following gene: 82702087

Centisome position: 34.74

GC content: 57.33

Gene sequence:

>1200_bases
ATGAGCGTTATCGATACGCTGCGTTTCGCCCTGCGCTCGCTCACCGCACATCGCCTGCGCACCTTGTTGTCCGCAACGGG
AATCGGCATCGGGATTGCGGCGGTTATTCTCCTGACTTCCATTGGGGAAGGAATTCATCAGTTCGTGATTTCGGAGTTCA
CCCAGTTCGGTACCAATATCATTACGGTCACCCCGGGAAAAATCAGGACTCACGGCAGGTCGCTGGGTGCGATCGGGAGC
GCTCGGCTCCTGACGATCGAGGATGCGCTGGCGTTAAAGAACTCTCCGTATGTTCAGCACGTTAACGCAGGCGTGATGGG
CAATGCGGAAATACGGGCGCGTGGACGGAGCCGGCGGGTCACCGTCTATGGTGAAAGCCCGGATTTTGCGCATACATTCA
ACATGAAGGTCGCAAGCGGACGGTTTCTGCCGGAGGATGATCCTCGCAATCCTCGCGCCTATGTGGTGCTGGGTTCAAAA
GTACGCACGGAATTGTTCGGCAGTGCGAATCCTCTGGGTGCTACGCTGCAAGTCGGCCTATCGCGCTTTCGTGTGATAGG
TGTCATGGAATCGAAGGGGCAGGTGCTGGGATTCGATCTGGACGATACGGTCTTTCTTCCCACTAGCCGCGCACTGGAAA
TTTTCAACCGCGAGGGTGTAATGGAAATCAACATTGCATACCAGCCAAGCGCGCCACTGGAAGCTGTAGTGGAGGATATA
GGCCGCATCCTCGTTTCAAGGCATGGGCGGGAAGATTTCACCATCACCCCCCAGCAGCAAATGCTGAATACGTTGAATAC
CGTTCTGGACGTGTTGATTTTCGCAGTTGCCGCGCTGGGGAGCATTTCCTTGCTGGTAGGGGCAGTCGGCATGGTTACGC
TCATGCATATTGCCGTGACTGAACGCGTTGCCGAAATCGGTTTGCTCACCGCCCTGGGCGCCACCCGTGCCCGCGTCCGC
CTTCTGTTCCTGACGGAATCCACAGTGCTCGCTACGTTGGGGGGCTTAGGGGGATTGGCTACGGGCGTGGGAATAGCATG
GTTGCTGAAATCCCTGGCAATCGGTCTGCCCGTGCAGATCCCCTGGAATTACACCGCCAGCGCACTCGGAATTTCTGTGC
TGGTCGGTCTTGCCGCCGGCGTTATTCCCGCCATGCGAGCGGCACGGTTGAATCCGATTGAAGCGCTTCGGGCCGAATAG

Upstream 100 bases:

>100_bases
ACCGGCAGCGCGTGCCGCCAGGCTCGATCCCGTGCGCGCACTGAGTGGAAAATAAGCGGAGATGAGGAAATGGATATAAA
AAGGGTATGAAAGGAGCGGC

Downstream 100 bases:

>100_bases
GTTTTTCGTTCACTCTGATATAGCTTCCTCTCCCCCATGTGGGAGAGGGATGGGGAGAGGATGACTTTGGCTTCTTCGCC
GCTCACTTGGTTTCTTTGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MSVIDTLRFALRSLTAHRLRTLLSATGIGIGIAAVILLTSIGEGIHQFVISEFTQFGTNIITVTPGKIRTHGRSLGAIGS
ARLLTIEDALALKNSPYVQHVNAGVMGNAEIRARGRSRRVTVYGESPDFAHTFNMKVASGRFLPEDDPRNPRAYVVLGSK
VRTELFGSANPLGATLQVGLSRFRVIGVMESKGQVLGFDLDDTVFLPTSRALEIFNREGVMEINIAYQPSAPLEAVVEDI
GRILVSRHGREDFTITPQQQMLNTLNTVLDVLIFAVAALGSISLLVGAVGMVTLMHIAVTERVAEIGLLTALGATRARVR
LLFLTESTVLATLGGLGGLATGVGIAWLLKSLAIGLPVQIPWNYTASALGISVLVGLAAGVIPAMRAARLNPIEALRAE

Sequences:

>Translated_399_residues
MSVIDTLRFALRSLTAHRLRTLLSATGIGIGIAAVILLTSIGEGIHQFVISEFTQFGTNIITVTPGKIRTHGRSLGAIGS
ARLLTIEDALALKNSPYVQHVNAGVMGNAEIRARGRSRRVTVYGESPDFAHTFNMKVASGRFLPEDDPRNPRAYVVLGSK
VRTELFGSANPLGATLQVGLSRFRVIGVMESKGQVLGFDLDDTVFLPTSRALEIFNREGVMEINIAYQPSAPLEAVVEDI
GRILVSRHGREDFTITPQQQMLNTLNTVLDVLIFAVAALGSISLLVGAVGMVTLMHIAVTERVAEIGLLTALGATRARVR
LLFLTESTVLATLGGLGGLATGVGIAWLLKSLAIGLPVQIPWNYTASALGISVLVGLAAGVIPAMRAARLNPIEALRAE
>Mature_398_residues
SVIDTLRFALRSLTAHRLRTLLSATGIGIGIAAVILLTSIGEGIHQFVISEFTQFGTNIITVTPGKIRTHGRSLGAIGSA
RLLTIEDALALKNSPYVQHVNAGVMGNAEIRARGRSRRVTVYGESPDFAHTFNMKVASGRFLPEDDPRNPRAYVVLGSKV
RTELFGSANPLGATLQVGLSRFRVIGVMESKGQVLGFDLDDTVFLPTSRALEIFNREGVMEINIAYQPSAPLEAVVEDIG
RILVSRHGREDFTITPQQQMLNTLNTVLDVLIFAVAALGSISLLVGAVGMVTLMHIAVTERVAEIGLLTALGATRARVRL
LFLTESTVLATLGGLGGLATGVGIAWLLKSLAIGLPVQIPWNYTASALGISVLVGLAAGVIPAMRAARLNPIEALRAE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=397, Percent_Identity=29.7229219143577, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42472; Mature: 42341

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIDTLRFALRSLTAHRLRTLLSATGIGIGIAAVILLTSIGEGIHQFVISEFTQFGTNI
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ITVTPGKIRTHGRSLGAIGSARLLTIEDALALKNSPYVQHVNAGVMGNAEIRARGRSRRV
EEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCEEECCCCCCCCCCEEECCCCCEE
TVYGESPDFAHTFNMKVASGRFLPEDDPRNPRAYVVLGSKVRTELFGSANPLGATLQVGL
EEEECCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHH
SRFRVIGVMESKGQVLGFDLDDTVFLPTSRALEIFNREGVMEINIAYQPSAPLEAVVEDI
HHHEEEEEEECCCCEEEECCCCCEECCCHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHH
GRILVSRHGREDFTITPQQQMLNTLNTVLDVLIFAVAALGSISLLVGAVGMVTLMHIAVT
HHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERVAEIGLLTALGATRARVRLLFLTESTVLATLGGLGGLATGVGIAWLLKSLAIGLPVQI
HHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEE
PWNYTASALGISVLVGLAAGVIPAMRAARLNPIEALRAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
SVIDTLRFALRSLTAHRLRTLLSATGIGIGIAAVILLTSIGEGIHQFVISEFTQFGTNI
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ITVTPGKIRTHGRSLGAIGSARLLTIEDALALKNSPYVQHVNAGVMGNAEIRARGRSRRV
EEECCCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCCEEECCCCCCCCCCEEECCCCCEE
TVYGESPDFAHTFNMKVASGRFLPEDDPRNPRAYVVLGSKVRTELFGSANPLGATLQVGL
EEEECCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCHHHHHHCCCCCCCCHHHHHHH
SRFRVIGVMESKGQVLGFDLDDTVFLPTSRALEIFNREGVMEINIAYQPSAPLEAVVEDI
HHHEEEEEEECCCCEEEECCCCCEECCCHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHH
GRILVSRHGREDFTITPQQQMLNTLNTVLDVLIFAVAALGSISLLVGAVGMVTLMHIAVT
HHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERVAEIGLLTALGATRARVRLLFLTESTVLATLGGLGGLATGVGIAWLLKSLAIGLPVQI
HHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEE
PWNYTASALGISVLVGLAAGVIPAMRAARLNPIEALRAE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA