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The map label for this gene is yciR [C]

Identifier: 82701959

GI number: 82701959

Start: 941374

End: 943491

Strand: Direct

Name: yciR [C]

Synonym: Nmul_A0828

Alternate gene names: 82701959

Gene position: 941374-943491 (Clockwise)

Preceding gene: 82701958

Following gene: 82701961

Centisome position: 29.56

GC content: 54.01

Gene sequence:

>2118_bases
TTGAGGCTGCCCGCATTCTTCGCTGTTTTCAATAGCAAGGAAACAAGAAAGGCACTGGAGGAAAAAACAGCGGAATTTAG
CCGCTCGCTTTCGCTGTGCAAAGCCACCGTGGAGTTGACGGCTGAAGGGCTCCTGGTGACCGACAGGGTGGGCCGCGTGC
TCTACCATAACCAGTTTTATCTGGAGATGTGGCCGATTCCCGAGGAGTTCATGGATAATATGTCACACCAGGCAATTGTC
CAGTATGGTTCGAGCCAATTAAAAGAGCCACAACGATTCCTGCACGCGACTGAGGAAATCTATCACGCATGGCCGCCTGA
AAGCCTTGACCTCCTTCAGTTTAACGATTGCCGGATATTTGAACGCTATACCAAGGCCAAAGTCCTGGAGGGGCAAAACA
TGGTGCGCGTCTGGAGCTTGAGAAACATTACGGAACGAAGGGAGGCGGATGCCTACAAAGCGCAGCTGGCGGCAATTGTC
GAGTCCTCCAACGATGCGATCATTGTCCAGGACCTCAACGGCATTATCACCAGCTGGAATGCCGGGGCAGAGGGGCTTTT
CGGGTATCGTGCCAGCGAGGTAATAGGCTCTTCCGTAGAGATACTCATTCCTCCGGACCTCCGGGAAGAAGAGGGAGATA
TCATGTGCCTCATCAAAAGCGGAAGACGCGCGGATCATTTTGAAACCGTGCGATGGGGAAAGGGCAGAAAACCAATTGAT
GTCTCGGTCACGATATCGGCAATGAAGGATAGGGCCGGTAATATCATCGGCGCATCCAAAATAGTGCGAGACATCACCCA
ACGCAAGGAATCGCAGGAACGCATCGAGTATCTGGCCCATTACGACTCGCTGACCGGGTTGCCTAACCGGACGCTGCTCT
CCGATCGCCTCAGGATTGCGATCGAGAACGCGAGGCGGTATTCCATACGATTGGCGCTGCTGTTCGTGGACATTGACCGT
TTCAAGCTGGTCAACGATTCGCTTGGCCATGAGATTGGCGACAAGCTGCTCAAGGCAGTCGCACAGCGAATGCAATCCAC
AGTGCGCCAGGCTGATACGGTGAGCCGGGTAGGGGGTGATGAATTTGTTGTCCTGCTAAGCCGGATCGAAACAGCGACGG
ATGCGGCGCGAAGCGCGGAAAAGCTTATTACCTCAATCTCCCAGCCCTATCAAATAGAAGAGCATGAGTTATTACTGACT
GCGAGCATCGGGATCAGCATTTATCCAGACAATGGCAAGGATGCGAGCAGTCTGACGCGCAATGCGGATGCCGCGATGTA
CTCGGCCAAAGGGCAGGGCAGGAACCGCTATCAGTTCTATTCTGAGGACTTGACTTATGCCGCGGCTGAACGGCTCAGAC
TTGAGCACGACTTGCGAGGGGCACTTTCGCGTGATGAAATTTTCCCGCTATATCAGCCTCAGATAGAGCTTGCCACGGGA
CGGGTCATCGGCGTGGAGGCCCTCATGCGCTGGAACCGGGCGGGGCAGGGGTTGATCTCTCCTGCAAGCTTTATTCCTGT
AGCCGAGGACAGTGGTCTAATCCTCGCTCTCGGTGAATACATCCTGAGAAAAGCCTGCCTGCAGGCGCGCCAATGGCACG
AACATCAGGGATTCCAAGGAACGATTGCGGTAAATGTTTCAGCGGTGCAGTTTCGCCAGAACGATTTCACGGATGTTGTG
TTGCGCGTCCTTTCCGAAACGGGTTTTCCGCCTGAATGCCTCGAACTGGAAGTCACCGAGAGCGTCGTGATGCAGGGATT
GGAATCGGTGGTGCAGAAGATGGGCATTCTTGAATCGCATGGTATAAAACTGGCCATCGACGATTTTGGCACTGGCTATT
CCAGCTTGTCCTATTTGCGGCAGTTTGCCATTGACCGGCTAAAAATAGACCAATCCTTTGTTCGTGACCTGCCGGGGGAT
GCGGATGCGCAGGCGATTATCCGCGCCATAGTTGCGATGGGGCGCAGCCTGGGCTTACGGGTGATGGCAGAAGGCGTGGA
GACGGAAGCGCAGGCCCGATTTCTGCAGGACATCGAGTGCACGGAAAGCCAGGGCTATCTCTATGCAAGGCCAATGAAGT
CAAATGATTTTGAAGCCTGGCTAAAAACCAGGAATTAG

Upstream 100 bases:

>100_bases
AGCATTAATTGTCAAGATTGGAAATTCTATGCACATGCTGGATCTTGGACAGCAACAGAATCAGGTCGAGTCGAAAGGCC
TCCTGCTGGAGGAATAGAAT

Downstream 100 bases:

>100_bases
GCTCTTCCTGGATTATGTTGGCCCGCCCGTCTGCTTCTTGCTGGCTTTAGGAATGTCATTAATTCTTACATTAAAATATC
CTGCAAGGAAACTTCTCCCT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MRLPAFFAVFNSKETRKALEEKTAEFSRSLSLCKATVELTAEGLLVTDRVGRVLYHNQFYLEMWPIPEEFMDNMSHQAIV
QYGSSQLKEPQRFLHATEEIYHAWPPESLDLLQFNDCRIFERYTKAKVLEGQNMVRVWSLRNITERREADAYKAQLAAIV
ESSNDAIIVQDLNGIITSWNAGAEGLFGYRASEVIGSSVEILIPPDLREEEGDIMCLIKSGRRADHFETVRWGKGRKPID
VSVTISAMKDRAGNIIGASKIVRDITQRKESQERIEYLAHYDSLTGLPNRTLLSDRLRIAIENARRYSIRLALLFVDIDR
FKLVNDSLGHEIGDKLLKAVAQRMQSTVRQADTVSRVGGDEFVVLLSRIETATDAARSAEKLITSISQPYQIEEHELLLT
ASIGISIYPDNGKDASSLTRNADAAMYSAKGQGRNRYQFYSEDLTYAAAERLRLEHDLRGALSRDEIFPLYQPQIELATG
RVIGVEALMRWNRAGQGLISPASFIPVAEDSGLILALGEYILRKACLQARQWHEHQGFQGTIAVNVSAVQFRQNDFTDVV
LRVLSETGFPPECLELEVTESVVMQGLESVVQKMGILESHGIKLAIDDFGTGYSSLSYLRQFAIDRLKIDQSFVRDLPGD
ADAQAIIRAIVAMGRSLGLRVMAEGVETEAQARFLQDIECTESQGYLYARPMKSNDFEAWLKTRN

Sequences:

>Translated_705_residues
MRLPAFFAVFNSKETRKALEEKTAEFSRSLSLCKATVELTAEGLLVTDRVGRVLYHNQFYLEMWPIPEEFMDNMSHQAIV
QYGSSQLKEPQRFLHATEEIYHAWPPESLDLLQFNDCRIFERYTKAKVLEGQNMVRVWSLRNITERREADAYKAQLAAIV
ESSNDAIIVQDLNGIITSWNAGAEGLFGYRASEVIGSSVEILIPPDLREEEGDIMCLIKSGRRADHFETVRWGKGRKPID
VSVTISAMKDRAGNIIGASKIVRDITQRKESQERIEYLAHYDSLTGLPNRTLLSDRLRIAIENARRYSIRLALLFVDIDR
FKLVNDSLGHEIGDKLLKAVAQRMQSTVRQADTVSRVGGDEFVVLLSRIETATDAARSAEKLITSISQPYQIEEHELLLT
ASIGISIYPDNGKDASSLTRNADAAMYSAKGQGRNRYQFYSEDLTYAAAERLRLEHDLRGALSRDEIFPLYQPQIELATG
RVIGVEALMRWNRAGQGLISPASFIPVAEDSGLILALGEYILRKACLQARQWHEHQGFQGTIAVNVSAVQFRQNDFTDVV
LRVLSETGFPPECLELEVTESVVMQGLESVVQKMGILESHGIKLAIDDFGTGYSSLSYLRQFAIDRLKIDQSFVRDLPGD
ADAQAIIRAIVAMGRSLGLRVMAEGVETEAQARFLQDIECTESQGYLYARPMKSNDFEAWLKTRN
>Mature_705_residues
MRLPAFFAVFNSKETRKALEEKTAEFSRSLSLCKATVELTAEGLLVTDRVGRVLYHNQFYLEMWPIPEEFMDNMSHQAIV
QYGSSQLKEPQRFLHATEEIYHAWPPESLDLLQFNDCRIFERYTKAKVLEGQNMVRVWSLRNITERREADAYKAQLAAIV
ESSNDAIIVQDLNGIITSWNAGAEGLFGYRASEVIGSSVEILIPPDLREEEGDIMCLIKSGRRADHFETVRWGKGRKPID
VSVTISAMKDRAGNIIGASKIVRDITQRKESQERIEYLAHYDSLTGLPNRTLLSDRLRIAIENARRYSIRLALLFVDIDR
FKLVNDSLGHEIGDKLLKAVAQRMQSTVRQADTVSRVGGDEFVVLLSRIETATDAARSAEKLITSISQPYQIEEHELLLT
ASIGISIYPDNGKDASSLTRNADAAMYSAKGQGRNRYQFYSEDLTYAAAERLRLEHDLRGALSRDEIFPLYQPQIELATG
RVIGVEALMRWNRAGQGLISPASFIPVAEDSGLILALGEYILRKACLQARQWHEHQGFQGTIAVNVSAVQFRQNDFTDVV
LRVLSETGFPPECLELEVTESVVMQGLESVVQKMGILESHGIKLAIDDFGTGYSSLSYLRQFAIDRLKIDQSFVRDLPGD
ADAQAIIRAIVAMGRSLGLRVMAEGVETEAQARFLQDIECTESQGYLYARPMKSNDFEAWLKTRN

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=558, Percent_Identity=35.4838709677419, Blast_Score=311, Evalue=1e-85,
Organism=Escherichia coli, GI87081921, Length=437, Percent_Identity=33.6384439359268, Blast_Score=259, Evalue=5e-70,
Organism=Escherichia coli, GI226510982, Length=452, Percent_Identity=28.7610619469027, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1787055, Length=470, Percent_Identity=27.0212765957447, Blast_Score=162, Evalue=8e-41,
Organism=Escherichia coli, GI1788381, Length=563, Percent_Identity=26.1101243339254, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI87081845, Length=248, Percent_Identity=38.7096774193548, Blast_Score=159, Evalue=8e-40,
Organism=Escherichia coli, GI87081980, Length=258, Percent_Identity=36.046511627907, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788502, Length=259, Percent_Identity=30.8880308880309, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786507, Length=277, Percent_Identity=33.2129963898917, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=31.0204081632653, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI87081743, Length=246, Percent_Identity=32.9268292682927, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI87081881, Length=189, Percent_Identity=39.1534391534392, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=32, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=34.9397590361446, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=36.3636363636364, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787262, Length=206, Percent_Identity=30.5825242718447, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1788849, Length=430, Percent_Identity=24.4186046511628, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081977, Length=167, Percent_Identity=33.5329341317365, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082096, Length=200, Percent_Identity=28.5, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=33.7423312883436, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=32.7380952380952, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788956, Length=157, Percent_Identity=33.1210191082803, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787410, Length=229, Percent_Identity=26.6375545851528, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788085, Length=184, Percent_Identity=26.6304347826087, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081974, Length=85, Percent_Identity=34.1176470588235, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 79353; Mature: 79353

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPAFFAVFNSKETRKALEEKTAEFSRSLSLCKATVELTAEGLLVTDRVGRVLYHNQFY
CCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHCCCEEE
LEMWPIPEEFMDNMSHQAIVQYGSSQLKEPQRFLHATEEIYHAWPPESLDLLQFNDCRIF
EEECCCCHHHHHCCCHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHH
ERYTKAKVLEGQNMVRVWSLRNITERREADAYKAQLAAIVESSNDAIIVQDLNGIITSWN
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEECCC
AGAEGLFGYRASEVIGSSVEILIPPDLREEEGDIMCLIKSGRRADHFETVRWGKGRKPID
CCCCCCCCCCHHHHCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCEE
VSVTISAMKDRAGNIIGASKIVRDITQRKESQERIEYLAHYDSLTGLPNRTLLSDRLRIA
EEEEEEEHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IENARRYSIRLALLFVDIDRFKLVNDSLGHEIGDKLLKAVAQRMQSTVRQADTVSRVGGD
HHCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EFVVLLSRIETATDAARSAEKLITSISQPYQIEEHELLLTASIGISIYPDNGKDASSLTR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEECCEEEECCCCCCHHHHHC
NADAAMYSAKGQGRNRYQFYSEDLTYAAAERLRLEHDLRGALSRDEIFPLYQPQIELATG
CCCHHEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECC
RVIGVEALMRWNRAGQGLISPASFIPVAEDSGLILALGEYILRKACLQARQWHEHQGFQG
CCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCE
TIAVNVSAVQFRQNDFTDVVLRVLSETGFPPECLELEVTESVVMQGLESVVQKMGILESH
EEEEEEEEEEECCCCHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHHHHHCCHHHC
GIKLAIDDFGTGYSSLSYLRQFAIDRLKIDQSFVRDLPGDADAQAIIRAIVAMGRSLGLR
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHCHHCCHH
VMAEGVETEAQARFLQDIECTESQGYLYARPMKSNDFEAWLKTRN
HHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHCCCC
>Mature Secondary Structure
MRLPAFFAVFNSKETRKALEEKTAEFSRSLSLCKATVELTAEGLLVTDRVGRVLYHNQFY
CCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHCCCEEE
LEMWPIPEEFMDNMSHQAIVQYGSSQLKEPQRFLHATEEIYHAWPPESLDLLQFNDCRIF
EEECCCCHHHHHCCCHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCCCCCCEEEECCCHHH
ERYTKAKVLEGQNMVRVWSLRNITERREADAYKAQLAAIVESSNDAIIVQDLNGIITSWN
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEECCC
AGAEGLFGYRASEVIGSSVEILIPPDLREEEGDIMCLIKSGRRADHFETVRWGKGRKPID
CCCCCCCCCCHHHHCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHCCCCCCCEE
VSVTISAMKDRAGNIIGASKIVRDITQRKESQERIEYLAHYDSLTGLPNRTLLSDRLRIA
EEEEEEEHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IENARRYSIRLALLFVDIDRFKLVNDSLGHEIGDKLLKAVAQRMQSTVRQADTVSRVGGD
HHCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EFVVLLSRIETATDAARSAEKLITSISQPYQIEEHELLLTASIGISIYPDNGKDASSLTR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEEEECCEEEECCCCCCHHHHHC
NADAAMYSAKGQGRNRYQFYSEDLTYAAAERLRLEHDLRGALSRDEIFPLYQPQIELATG
CCCHHEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECC
RVIGVEALMRWNRAGQGLISPASFIPVAEDSGLILALGEYILRKACLQARQWHEHQGFQG
CCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCE
TIAVNVSAVQFRQNDFTDVVLRVLSETGFPPECLELEVTESVVMQGLESVVQKMGILESH
EEEEEEEEEEECCCCHHHHHHHHHHHCCCCCHHEEEHHHHHHHHHHHHHHHHHHCCHHHC
GIKLAIDDFGTGYSSLSYLRQFAIDRLKIDQSFVRDLPGDADAQAIIRAIVAMGRSLGLR
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCHHHHHHHHHHHCHHCCHH
VMAEGVETEAQARFLQDIECTESQGYLYARPMKSNDFEAWLKTRN
HHHCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]