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The map label for this gene is hitA [H]

Identifier: 82701944

GI number: 82701944

Start: 927972

End: 928325

Strand: Reverse

Name: hitA [H]

Synonym: Nmul_A0811

Alternate gene names: 82701944

Gene position: 928325-927972 (Counterclockwise)

Preceding gene: 82701945

Following gene: 82701943

Centisome position: 29.15

GC content: 51.41

Gene sequence:

>354_bases
ATGGACAGTTGTATTTTTTGCAAGATTGTGCGAGGAGAAATTCCGAGCGAGAAAGTGTATGAGGATGCCCGCGTTTATGC
ATTCCATGATATCCACCCGGCGGCCCCGGTACACTTCATGCTGATACCCAAACTGCACATCAACTCGCTTGCCGATGTGG
AAAATGCCCATAGCGCCTTGCTCGGTGAGATGATGGTACTGGTGCCCAAGCTGGCAAGGGAACAAGGTTGTACGGATGGT
TTTCGTACGGTAATCAATACTGGACGAGTAGGCGGCCAAGAAGTACATCACCTGCACATCCACATCATCGGTGGCATGGA
ACGCCTGCCGGGAATGATTGCTCGCGGGAAATAA

Upstream 100 bases:

>100_bases
GTTACGCCGGCGGGAAGGGGTTTCAGGAATTGATGAAAAAGCTGCCCGCAAAGCAGGACTGGCAGATAACGGAATCGGCA
GGATGAATCAGGATAAGTAA

Downstream 100 bases:

>100_bases
AGGTAATGAGCAAAGGATAAGGGATAAAGGAGGAATAATGGGATCATTCAGCATCTGGCATTGGCTGATCGTTCTGCTGA
TCGTTGTTCTGGTATTCGGT

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MDSCIFCKIVRGEIPSEKVYEDARVYAFHDIHPAAPVHFMLIPKLHINSLADVENAHSALLGEMMVLVPKLAREQGCTDG
FRTVINTGRVGGQEVHHLHIHIIGGMERLPGMIARGK

Sequences:

>Translated_117_residues
MDSCIFCKIVRGEIPSEKVYEDARVYAFHDIHPAAPVHFMLIPKLHINSLADVENAHSALLGEMMVLVPKLAREQGCTDG
FRTVINTGRVGGQEVHHLHIHIIGGMERLPGMIARGK
>Mature_117_residues
MDSCIFCKIVRGEIPSEKVYEDARVYAFHDIHPAAPVHFMLIPKLHINSLADVENAHSALLGEMMVLVPKLAREQGCTDG
FRTVINTGRVGGQEVHHLHIHIIGGMERLPGMIARGK

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=105, Percent_Identity=45.7142857142857, Blast_Score=108, Evalue=8e-25,
Organism=Homo sapiens, GI14211923, Length=104, Percent_Identity=40.3846153846154, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787346, Length=116, Percent_Identity=43.9655172413793, Blast_Score=97, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17506713, Length=106, Percent_Identity=42.4528301886792, Blast_Score=111, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320078, Length=111, Percent_Identity=37.8378378378378, Blast_Score=80, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28574010, Length=112, Percent_Identity=45.5357142857143, Blast_Score=106, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24581222, Length=112, Percent_Identity=45.5357142857143, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 12961; Mature: 12961

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSCIFCKIVRGEIPSEKVYEDARVYAFHDIHPAAPVHFMLIPKLHINSLADVENAHSAL
CCCEEEEEEECCCCCCHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
LGEMMVLVPKLAREQGCTDGFRTVINTGRVGGQEVHHLHIHIIGGMERLPGMIARGK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEEEECCHHHCCCCCCCCC
>Mature Secondary Structure
MDSCIFCKIVRGEIPSEKVYEDARVYAFHDIHPAAPVHFMLIPKLHINSLADVENAHSAL
CCCEEEEEEECCCCCCHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
LGEMMVLVPKLAREQGCTDGFRTVINTGRVGGQEVHHLHIHIIGGMERLPGMIARGK
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEEEEECCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA