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The map label for this gene is fbp [H]

Identifier: 82701884

GI number: 82701884

Start: 874004

End: 874465

Strand: Direct

Name: fbp [H]

Synonym: Nmul_A0751

Alternate gene names: 82701884

Gene position: 874004-874465 (Clockwise)

Preceding gene: 82701882

Following gene: 82701885

Centisome position: 27.45

GC content: 57.58

Gene sequence:

>462_bases
ATGTCCAGGATAAATACACTGATCAGTTTGGGAATATTCATGCTGGGCGCTTTGCTGTTGCCCCAACCCGCCATTTCGGA
AACGGGACAGACCCTGTCTGCCGTGACCCAGCCCATCAAGCAGGATACCAAAATAGGAAGCGGTGAAGAAGCGGCGGTTG
GCAAGATGGTTGAAGTGCACTATACCGGCTGGCTTTACGATGCGAGCGCTCCCGACAAAAAGGGCGGGAAGTTCGACAGC
TCGCGTGACCGTGGCATGCCCTTCTCGTTCCTTGTCGGCGCGGGACGAGTGATCAAAGGTTGGGACCGGGGCGTGATCGG
GATGAAGGTGGGAGGCCAGCGCACATTGATCATTCCGCCCCAACTGGCCTACGGGTCGGAAGGGCGGGGAACTATCCCGC
CAAACGCTACCCTGATTTTCGAGGTAGAGCTTTTGGGAGTGCGCCAGGGTTCGACACACTGA

Upstream 100 bases:

>100_bases
CTGAACGAAGCCTTCATGATGCTACAGCCGCCCCGTGGGTTGACGGTATAATAAGAGGCAATAAGTATGAAAGGTTTTCA
TTTCAATTTTCGAGGTCCTC

Downstream 100 bases:

>100_bases
TTGATATCACCCGATTTTCGCGCCGCCGCTACCTCGCCGAGAAAAGCGGGATTTTACCCAGATCAACTCATTGGTTTCCC
CCTGTGCGGATAATACCTGT

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MSRINTLISLGIFMLGALLLPQPAISETGQTLSAVTQPIKQDTKIGSGEEAAVGKMVEVHYTGWLYDASAPDKKGGKFDS
SRDRGMPFSFLVGAGRVIKGWDRGVIGMKVGGQRTLIIPPQLAYGSEGRGTIPPNATLIFEVELLGVRQGSTH

Sequences:

>Translated_153_residues
MSRINTLISLGIFMLGALLLPQPAISETGQTLSAVTQPIKQDTKIGSGEEAAVGKMVEVHYTGWLYDASAPDKKGGKFDS
SRDRGMPFSFLVGAGRVIKGWDRGVIGMKVGGQRTLIIPPQLAYGSEGRGTIPPNATLIFEVELLGVRQGSTH
>Mature_152_residues
SRINTLISLGIFMLGALLLPQPAISETGQTLSAVTQPIKQDTKIGSGEEAAVGKMVEVHYTGWLYDASAPDKKGGKFDSS
RDRGMPFSFLVGAGRVIKGWDRGVIGMKVGGQRTLIIPPQLAYGSEGRGTIPPNATLIFEVELLGVRQGSTH

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI8923659, Length=148, Percent_Identity=36.4864864864865, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI4503729, Length=97, Percent_Identity=51.5463917525773, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI224809329, Length=132, Percent_Identity=42.4242424242424, Blast_Score=93, Evalue=7e-20,
Organism=Homo sapiens, GI224809327, Length=132, Percent_Identity=42.4242424242424, Blast_Score=93, Evalue=7e-20,
Organism=Homo sapiens, GI4758384, Length=132, Percent_Identity=42.4242424242424, Blast_Score=93, Evalue=7e-20,
Organism=Homo sapiens, GI17149836, Length=93, Percent_Identity=52.6881720430108, Blast_Score=93, Evalue=8e-20,
Organism=Homo sapiens, GI4503725, Length=93, Percent_Identity=52.6881720430108, Blast_Score=93, Evalue=8e-20,
Organism=Homo sapiens, GI224809331, Length=132, Percent_Identity=42.4242424242424, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI4758380, Length=96, Percent_Identity=48.9583333333333, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI192448443, Length=99, Percent_Identity=49.4949494949495, Blast_Score=87, Evalue=6e-18,
Organism=Homo sapiens, GI206725530, Length=97, Percent_Identity=47.4226804123711, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI17149844, Length=97, Percent_Identity=47.4226804123711, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI17149842, Length=97, Percent_Identity=47.4226804123711, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI150010552, Length=127, Percent_Identity=39.3700787401575, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI206725547, Length=100, Percent_Identity=46, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI31317231, Length=101, Percent_Identity=45.5445544554455, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI33469985, Length=95, Percent_Identity=46.3157894736842, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI4503727, Length=96, Percent_Identity=40.625, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789745, Length=110, Percent_Identity=43.6363636363636, Blast_Score=76, Evalue=8e-16,
Organism=Escherichia coli, GI87082390, Length=103, Percent_Identity=46.6019417475728, Blast_Score=71, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71993519, Length=96, Percent_Identity=52.0833333333333, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540882, Length=135, Percent_Identity=37.7777777777778, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561782, Length=94, Percent_Identity=50, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561778, Length=100, Percent_Identity=42, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320727, Length=103, Percent_Identity=51.4563106796116, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324194, Length=96, Percent_Identity=51.0416666666667, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323566, Length=109, Percent_Identity=42.2018348623853, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323482, Length=110, Percent_Identity=40.9090909090909, Blast_Score=79, Evalue=2e-16,
Organism=Drosophila melanogaster, GI281363946, Length=100, Percent_Identity=51, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17352457, Length=100, Percent_Identity=51, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24655568, Length=96, Percent_Identity=55.2083333333333, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24647110, Length=108, Percent_Identity=50, Blast_Score=96, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21356629, Length=102, Percent_Identity=52.9411764705882, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24583150, Length=110, Percent_Identity=46.3636363636364, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16283; Mature: 16152

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRINTLISLGIFMLGALLLPQPAISETGQTLSAVTQPIKQDTKIGSGEEAAVGKMVEVH
CCHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
YTGWLYDASAPDKKGGKFDSSRDRGMPFSFLVGAGRVIKGWDRGVIGMKVGGQRTLIIPP
EEEEEEECCCCCCCCCCCCCCCCCCCCCHHEECCCCEEECCCCCEEEEEECCCEEEEECC
QLAYGSEGRGTIPPNATLIFEVELLGVRQGSTH
CCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCC
>Mature Secondary Structure 
SRINTLISLGIFMLGALLLPQPAISETGQTLSAVTQPIKQDTKIGSGEEAAVGKMVEVH
CHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
YTGWLYDASAPDKKGGKFDSSRDRGMPFSFLVGAGRVIKGWDRGVIGMKVGGQRTLIIPP
EEEEEEECCCCCCCCCCCCCCCCCCCCCHHEECCCCEEECCCCCEEEEEECCCEEEEECC
QLAYGSEGRGTIPPNATLIFEVELLGVRQGSTH
CCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]