Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 82701881

GI number: 82701881

Start: 871345

End: 872256

Strand: Direct

Name: xerD [H]

Synonym: Nmul_A0748

Alternate gene names: 82701881

Gene position: 871345-872256 (Clockwise)

Preceding gene: 82701880

Following gene: 82701882

Centisome position: 27.36

GC content: 56.36

Gene sequence:

>912_bases
ATGAGGGTATCTGAGCGGAACCCGGAACTGCTCGATGAATTCTGCGATGCGCTGTGGCTGGAAGATGGGCTCTCGCGCAA
CACAATGGAGAGCTATCGCAGCGATCTGGAGCAGTTCGGTGACTGGTTCGCCCGACAGAAACCGGATGACAGCAGTTTTC
TGACGGTCACGCATTCCGATCTGCTGGGATTCATGACGGGCAGGTTTTCCGCTGGAATGAAGGCCAGCACCACTAGCCGC
GAGCTCTCGAGCCTAAAGCGGTTTTACCGCTTTCTGTTGCGCCAGGGAAAGATCAATGCAGATCCCACCCTCAATATCGA
TACACCCAGGCTTCCTCGCAACCTGCCGGTGAGTTTAACCGAGGCCGACGTGGAAGCCCTGCTTGGCGCACCCGACGTGA
CCTTTCCGTTGGGATTACGGGATCGCGCCATGCTCGAGGTGCTTTATGCAAGCGGCCTTCGGGTTTCAGAGCTTGTGAGC
CTGGAAAGTGGACAGATCAGCCTGGACATGGGCGTGGTGCGCATCATGGGGAAGGGGGGGAAAGAACGCCTGACACCGCT
GGGGGAAGAGGCGCTGGAATGGATGGTTCGCTACATCAAGGAAATCCGTCCCGGGCTGCTGGATGGAAAATCGAGTAATG
CGCTGTTCGTCACTTACCGCGGCGCAGGCATGACCCGTCAGGCTTTCTGGTATCTGATCAAACGCTATGCGCGGCAGGCG
GGTATCACGAAGCCATTGTCGCCCCATGGATTGCGTCATGCCTTTGCGACTCATCTGCTCAATCATGGTGCCGATTTGCG
CGTAGTGCAATTGCTGCTCGGCCACGCGGATATTTCAACCACGCAGATATACACTCATGTCGCGCGTGAAAGATTGAAAA
AAATCCACGAAATGCATCATCCGAGAGGGTGA

Upstream 100 bases:

>100_bases
ATTCCCTGTCATCGTGTTATCGCCAAAAGCGGCGGTCTTGGAGGTTTCATGAACGCCAGCGATGGATTGCCGCTCACCAT
TAAGCGCTGGCTATTGCAGC

Downstream 100 bases:

>100_bases
GGCAAAATTTTACGGCCTGGAACCGCGACGAAGAAAATTACTTTCGCCCTCCACAAGAAACAAATCCTATCGGCATAGGC
TCAGCCAGGCCAGATTGCCG

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MRVSERNPELLDEFCDALWLEDGLSRNTMESYRSDLEQFGDWFARQKPDDSSFLTVTHSDLLGFMTGRFSAGMKASTTSR
ELSSLKRFYRFLLRQGKINADPTLNIDTPRLPRNLPVSLTEADVEALLGAPDVTFPLGLRDRAMLEVLYASGLRVSELVS
LESGQISLDMGVVRIMGKGGKERLTPLGEEALEWMVRYIKEIRPGLLDGKSSNALFVTYRGAGMTRQAFWYLIKRYARQA
GITKPLSPHGLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKKIHEMHHPRG

Sequences:

>Translated_303_residues
MRVSERNPELLDEFCDALWLEDGLSRNTMESYRSDLEQFGDWFARQKPDDSSFLTVTHSDLLGFMTGRFSAGMKASTTSR
ELSSLKRFYRFLLRQGKINADPTLNIDTPRLPRNLPVSLTEADVEALLGAPDVTFPLGLRDRAMLEVLYASGLRVSELVS
LESGQISLDMGVVRIMGKGGKERLTPLGEEALEWMVRYIKEIRPGLLDGKSSNALFVTYRGAGMTRQAFWYLIKRYARQA
GITKPLSPHGLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKKIHEMHHPRG
>Mature_303_residues
MRVSERNPELLDEFCDALWLEDGLSRNTMESYRSDLEQFGDWFARQKPDDSSFLTVTHSDLLGFMTGRFSAGMKASTTSR
ELSSLKRFYRFLLRQGKINADPTLNIDTPRLPRNLPVSLTEADVEALLGAPDVTFPLGLRDRAMLEVLYASGLRVSELVS
LESGQISLDMGVVRIMGKGGKERLTPLGEEALEWMVRYIKEIRPGLLDGKSSNALFVTYRGAGMTRQAFWYLIKRYARQA
GITKPLSPHGLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKKIHEMHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=53.4013605442177, Blast_Score=315, Evalue=3e-87,
Organism=Escherichia coli, GI1790244, Length=232, Percent_Identity=39.6551724137931, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1790768, Length=169, Percent_Identity=32.5443786982249, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790767, Length=168, Percent_Identity=29.7619047619048, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34224; Mature: 34224

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSERNPELLDEFCDALWLEDGLSRNTMESYRSDLEQFGDWFARQKPDDSSFLTVTHSD
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHH
LLGFMTGRFSAGMKASTTSRELSSLKRFYRFLLRQGKINADPTLNIDTPRLPRNLPVSLT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
EADVEALLGAPDVTFPLGLRDRAMLEVLYASGLRVSELVSLESGQISLDMGVVRIMGKGG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEHHHHHHHHCCCC
KERLTPLGEEALEWMVRYIKEIRPGLLDGKSSNALFVTYRGAGMTRQAFWYLIKRYARQA
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
GITKPLSPHGLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKKIHEMHH
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
PRG
CCC
>Mature Secondary Structure
MRVSERNPELLDEFCDALWLEDGLSRNTMESYRSDLEQFGDWFARQKPDDSSFLTVTHSD
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHH
LLGFMTGRFSAGMKASTTSRELSSLKRFYRFLLRQGKINADPTLNIDTPRLPRNLPVSLT
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
EADVEALLGAPDVTFPLGLRDRAMLEVLYASGLRVSELVSLESGQISLDMGVVRIMGKGG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCEEEHHHHHHHHCCCC
KERLTPLGEEALEWMVRYIKEIRPGLLDGKSSNALFVTYRGAGMTRQAFWYLIKRYARQA
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
GITKPLSPHGLRHAFATHLLNHGADLRVVQLLLGHADISTTQIYTHVARERLKKIHEMHH
CCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
PRG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]