Click here to switch to the map view.

The map label for this gene is orn [H]

Identifier: 82701847

GI number: 82701847

Start: 824704

End: 825258

Strand: Direct

Name: orn [H]

Synonym: Nmul_A0714

Alternate gene names: 82701847

Gene position: 824704-825258 (Clockwise)

Preceding gene: 82701843

Following gene: 82701848

Centisome position: 25.9

GC content: 53.15

Gene sequence:

>555_bases
ATGACACAAGACAATGGCCGTCTCATCTGGATCGATATGGAAATGAGCGGGCTCAGCCCGGACAGGGACCGCATACTCGA
AATCGCTCTGGTCGTAACGGATTCGCAGTTGGAGGTTCTTGCAGAAGCTCCGGTGCTGGTCTTGTCGCAATCCGAGTCGG
TGCTCGAGGGAATGGATAGCTGGAACAAATCCACGCATGCAAAATCGGGCCTGGTGGAAAAGGTGCGGGCATCCGGGCTG
ACGGAAGCCGAAGTGGAAGTCCATATGATTGCTTTTCTTCAAGAACATATTTCCGCCGGAGTTTCGCCAATGTGCGGCAA
TTCGATCTGCCAGGATCGGCGTTTTCTGGCACGCTGGATGCCTCGGCTGGAAGCCTATTTCCATTACCGGAACCTCGACG
TAAGCACTTTGAAGGAACTGGCAAAACGCTGGAAGCCAGAAATTCTGGCGGGCGTGACGAAACAGTGCAAGCATGAAGCG
CTGTCGGATATATACGACTCCATTGCGGAGCTGAAATATTACCGTGAACATTTCATGCAGGCGGTAGAGCCATGA

Upstream 100 bases:

>100_bases
ATTGGAGTTGTACTGCCCCAAATCAGGATTACGGTTGAAGGATGACTGATCAATAGTGATATGACACAATTACATGTCGA
AAATTCAGGGCGATTCAATT

Downstream 100 bases:

>100_bases
GTCGGACCGATATAAAAAAATCCCGGGACTAGGCAGGCTATTTCCGTACCTCATTTTTCAACTTCTCAGGAAAGATTGAG
CATGTCGAAAGGCACCTTGT

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MTQDNGRLIWIDMEMSGLSPDRDRILEIALVVTDSQLEVLAEAPVLVLSQSESVLEGMDSWNKSTHAKSGLVEKVRASGL
TEAEVEVHMIAFLQEHISAGVSPMCGNSICQDRRFLARWMPRLEAYFHYRNLDVSTLKELAKRWKPEILAGVTKQCKHEA
LSDIYDSIAELKYYREHFMQAVEP

Sequences:

>Translated_184_residues
MTQDNGRLIWIDMEMSGLSPDRDRILEIALVVTDSQLEVLAEAPVLVLSQSESVLEGMDSWNKSTHAKSGLVEKVRASGL
TEAEVEVHMIAFLQEHISAGVSPMCGNSICQDRRFLARWMPRLEAYFHYRNLDVSTLKELAKRWKPEILAGVTKQCKHEA
LSDIYDSIAELKYYREHFMQAVEP
>Mature_183_residues
TQDNGRLIWIDMEMSGLSPDRDRILEIALVVTDSQLEVLAEAPVLVLSQSESVLEGMDSWNKSTHAKSGLVEKVRASGLT
EAEVEVHMIAFLQEHISAGVSPMCGNSICQDRRFLARWMPRLEAYFHYRNLDVSTLKELAKRWKPEILAGVTKQCKHEAL
SDIYDSIAELKYYREHFMQAVEP

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides [H]

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

Organism=Homo sapiens, GI224496106, Length=174, Percent_Identity=40.8045977011494, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI87082382, Length=180, Percent_Identity=59.4444444444444, Blast_Score=234, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17557752, Length=170, Percent_Identity=47.0588235294118, Blast_Score=166, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=182, Percent_Identity=36.8131868131868, Blast_Score=113, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355135, Length=174, Percent_Identity=38.5057471264368, Blast_Score=151, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20937; Mature: 20806

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDNGRLIWIDMEMSGLSPDRDRILEIALVVTDSQLEVLAEAPVLVLSQSESVLEGMDS
CCCCCCEEEEEEEECCCCCCCHHHHHHHHHEEECHHHHHHHHCCEEEEECCHHHHHHHHH
WNKSTHAKSGLVEKVRASGLTEAEVEVHMIAFLQEHISAGVSPMCGNSICQDRRFLARWM
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
PRLEAYFHYRNLDVSTLKELAKRWKPEILAGVTKQCKHEALSDIYDSIAELKYYREHFMQ
HHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVEP
HCCC
>Mature Secondary Structure 
TQDNGRLIWIDMEMSGLSPDRDRILEIALVVTDSQLEVLAEAPVLVLSQSESVLEGMDS
CCCCCEEEEEEEECCCCCCCHHHHHHHHHEEECHHHHHHHHCCEEEEECCHHHHHHHHH
WNKSTHAKSGLVEKVRASGLTEAEVEVHMIAFLQEHISAGVSPMCGNSICQDRRFLARWM
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
PRLEAYFHYRNLDVSTLKELAKRWKPEILAGVTKQCKHEALSDIYDSIAELKYYREHFMQ
HHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVEP
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]