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The map label for this gene is csd1 [H]

Identifier: 82701832

GI number: 82701832

Start: 805874

End: 807133

Strand: Direct

Name: csd1 [H]

Synonym: Nmul_A0699

Alternate gene names: 82701832

Gene position: 805874-807133 (Clockwise)

Preceding gene: 82701831

Following gene: 82701833

Centisome position: 25.31

GC content: 52.94

Gene sequence:

>1260_bases
ATGAAAATCATAGATTCCACGCTGCAACCTCAGATTGATTCGACGCTCGACGTCGCACGTGTGCGTGCCGATTTTCCGAT
TCTGGAGCTTCAGGTCGAAGGAAAGCCGCTGGTCTACCTCGATAATGCAGCCTCCAGCCAGATGCCGCAGCCCGTGATCG
ATCGCCTGGTGCGTTACCAGACAAGGCAGCACGCAAATATCAATCGGGGTGTGCATTATTTATCCGAAACTGCCACGGCA
GAATATGAGGCGGCGCGCTGTAAATTGCAGCGCTTCATCAATGCGCGTGAAGACAGGGAGGTCATCTTTACCAGCGGGAC
GACAGATTCCATCAACCTTGTGATGCACGGGTATGGACGCAAATTCATCGGCGCGGGTGATGAAATCATCCTGACTACCT
TGGAGCATCATTCGAATATCGTTCCATGGCAGATGCTGGCGGAAGAAAAAGGGGCAAGGATACGTGTCGTGCCGATCAAC
GACGCCGGTGAACTTCTCATCGATGATTATGAGAAGCTTTTCAACGAGCGTACGAAGTTCGTGGGTGTGATGCACGTATC
GAATGCTTTGGGGACGATCAACCCGGTCAGGGAAATGATCGCCTTCGCGCATGCCCGCGGTGTTCCGGTGCTGGTGGATG
GCGCGCAGGCTGCGCCGCATATGAAAGTGGATGTCCAGGAGCTCGACTGCGATTTCTATGCATTTTCGGGACACAAAATG
TGTGGCCCGACAGGCATTGGTATTCTGTACGGAAAAGCGGAACTCCTGGAGCGCATGCAGCCGTTCAAAGGCGGCGGCGA
CATGATTCTATCGGTGACATTCGAAAGAACCACCTACAATTCCATTCCACACAAATTCGAAGCAGGAACTCCGCCCATTG
CAGCCGCTATCGGGCTTGGCGCTGCCGTCGATTATTTATCGAATGTCGGCATCAATGCCATCGCCGCGTACGAGATTGAG
CTGCTCAATTACGCAACCGAACAGATACTCCAGATACCCGGAGTGCGCATCATAGGCACAGCAGCGAAAAAAACCGCGGT
GCTGTCTTTCGAGGTGGCGGGTGTGCATCCGCACGATGTCGGTACGCTTTTGAATCAGGAAGGCGTTGCCGTTCGTACCG
GCCATCACTGCGTGCAACCCGTGATGTTGCGCCTCAAGGTGCCTGCCACTACACGCGCTTCATTTGCGTTTTATAATACA
ATGGCTGAGGTAGATACTTTCATCGCTGGCATTCGTACTGTGCAAAAGATATTTATTTAA

Upstream 100 bases:

>100_bases
CTTATGCGTTTGGTGCGGAGATCATTGATCGTATTCCTATCGCATCGCTCAAATACCGGCTTGAACGGACAGTGCTGGAA
CAAACCAAAAAAACTGAGCC

Downstream 100 bases:

>100_bases
TGACTACCAAATCTCTTTATCAAGAAGTCATTCTCGACCACAACAGGAAACCCCGCAATTACGGCAAGCTGGACAAGGCA
AGCCATCATGCGGTCGGGCA

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKIIDSTLQPQIDSTLDVARVRADFPILELQVEGKPLVYLDNAASSQMPQPVIDRLVRYQTRQHANINRGVHYLSETATA
EYEAARCKLQRFINAREDREVIFTSGTTDSINLVMHGYGRKFIGAGDEIILTTLEHHSNIVPWQMLAEEKGARIRVVPIN
DAGELLIDDYEKLFNERTKFVGVMHVSNALGTINPVREMIAFAHARGVPVLVDGAQAAPHMKVDVQELDCDFYAFSGHKM
CGPTGIGILYGKAELLERMQPFKGGGDMILSVTFERTTYNSIPHKFEAGTPPIAAAIGLGAAVDYLSNVGINAIAAYEIE
LLNYATEQILQIPGVRIIGTAAKKTAVLSFEVAGVHPHDVGTLLNQEGVAVRTGHHCVQPVMLRLKVPATTRASFAFYNT
MAEVDTFIAGIRTVQKIFI

Sequences:

>Translated_419_residues
MKIIDSTLQPQIDSTLDVARVRADFPILELQVEGKPLVYLDNAASSQMPQPVIDRLVRYQTRQHANINRGVHYLSETATA
EYEAARCKLQRFINAREDREVIFTSGTTDSINLVMHGYGRKFIGAGDEIILTTLEHHSNIVPWQMLAEEKGARIRVVPIN
DAGELLIDDYEKLFNERTKFVGVMHVSNALGTINPVREMIAFAHARGVPVLVDGAQAAPHMKVDVQELDCDFYAFSGHKM
CGPTGIGILYGKAELLERMQPFKGGGDMILSVTFERTTYNSIPHKFEAGTPPIAAAIGLGAAVDYLSNVGINAIAAYEIE
LLNYATEQILQIPGVRIIGTAAKKTAVLSFEVAGVHPHDVGTLLNQEGVAVRTGHHCVQPVMLRLKVPATTRASFAFYNT
MAEVDTFIAGIRTVQKIFI
>Mature_419_residues
MKIIDSTLQPQIDSTLDVARVRADFPILELQVEGKPLVYLDNAASSQMPQPVIDRLVRYQTRQHANINRGVHYLSETATA
EYEAARCKLQRFINAREDREVIFTSGTTDSINLVMHGYGRKFIGAGDEIILTTLEHHSNIVPWQMLAEEKGARIRVVPIN
DAGELLIDDYEKLFNERTKFVGVMHVSNALGTINPVREMIAFAHARGVPVLVDGAQAAPHMKVDVQELDCDFYAFSGHKM
CGPTGIGILYGKAELLERMQPFKGGGDMILSVTFERTTYNSIPHKFEAGTPPIAAAIGLGAAVDYLSNVGINAIAAYEIE
LLNYATEQILQIPGVRIIGTAAKKTAVLSFEVAGVHPHDVGTLLNQEGVAVRTGHHCVQPVMLRLKVPATTRASFAFYNT
MAEVDTFIAGIRTVQKIFI

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=270, Percent_Identity=28.8888888888889, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI156713448, Length=427, Percent_Identity=26.6978922716628, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1787970, Length=404, Percent_Identity=48.7623762376238, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1789175, Length=401, Percent_Identity=41.3965087281795, Blast_Score=328, Evalue=5e-91,
Organism=Escherichia coli, GI48994898, Length=268, Percent_Identity=27.2388059701493, Blast_Score=101, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI25143064, Length=229, Percent_Identity=27.9475982532751, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI193211090, Length=417, Percent_Identity=23.9808153477218, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=230, Percent_Identity=32.1739130434783, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI20129463, Length=307, Percent_Identity=31.5960912052117, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 46068; Mature: 46068

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIDSTLQPQIDSTLDVARVRADFPILELQVEGKPLVYLDNAASSQMPQPVIDRLVRYQ
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHH
TRQHANINRGVHYLSETATAEYEAARCKLQRFINAREDREVIFTSGTTDSINLVMHGYGR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCC
KFIGAGDEIILTTLEHHSNIVPWQMLAEEKGARIRVVPINDAGELLIDDYEKLFNERTKF
EECCCCCEEEEEEEHHCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHE
VGVMHVSNALGTINPVREMIAFAHARGVPVLVDGAQAAPHMKVDVQELDCDFYAFSGHKM
EEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEHHHCCCCEEEECCCCC
CGPTGIGILYGKAELLERMQPFKGGGDMILSVTFERTTYNSIPHKFEAGTPPIAAAIGLG
CCCCCCEEEECHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
AAVDYLSNVGINAIAAYEIELLNYATEQILQIPGVRIIGTAAKKTAVLSFEVAGVHPHDV
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEECCCCHHH
GTLLNQEGVAVRTGHHCVQPVMLRLKVPATTRASFAFYNTMAEVDTFIAGIRTVQKIFI
HHHHCCCCCEEECCCHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIIDSTLQPQIDSTLDVARVRADFPILELQVEGKPLVYLDNAASSQMPQPVIDRLVRYQ
CCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHHHHHHH
TRQHANINRGVHYLSETATAEYEAARCKLQRFINAREDREVIFTSGTTDSINLVMHGYGR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCC
KFIGAGDEIILTTLEHHSNIVPWQMLAEEKGARIRVVPINDAGELLIDDYEKLFNERTKF
EECCCCCEEEEEEEHHCCCCCCHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHE
VGVMHVSNALGTINPVREMIAFAHARGVPVLVDGAQAAPHMKVDVQELDCDFYAFSGHKM
EEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEHHHCCCCEEEECCCCC
CGPTGIGILYGKAELLERMQPFKGGGDMILSVTFERTTYNSIPHKFEAGTPPIAAAIGLG
CCCCCCEEEECHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHH
AAVDYLSNVGINAIAAYEIELLNYATEQILQIPGVRIIGTAAKKTAVLSFEVAGVHPHDV
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEECCCCHHH
GTLLNQEGVAVRTGHHCVQPVMLRLKVPATTRASFAFYNTMAEVDTFIAGIRTVQKIFI
HHHHCCCCCEEECCCHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]