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The map label for this gene is yaeL [C]

Identifier: 82701797

GI number: 82701797

Start: 759353

End: 760720

Strand: Direct

Name: yaeL [C]

Synonym: Nmul_A0664

Alternate gene names: 82701797

Gene position: 759353-760720 (Clockwise)

Preceding gene: 82701796

Following gene: 82701798

Centisome position: 23.85

GC content: 54.31

Gene sequence:

>1368_bases
ATGACATTCCTTTTCACAATTGCCGCTTTCGTTGTTGCTCTCGGCCTGCTGATCGTATTTCATGAATTCGGCCATTACCT
CGTCGCCCGCTGGTGTGGAGTAAAAGTACTCCGTTTCTCCATCGGTTTCGGTCATCCGCTCATGCGGAAGCAGGTGGGAA
AAGACCAGACCGAATGGGTTATTGCCGCCTTTCCTCTTGGCGGTTATGTGAAGATGCTCGATGAACGTGAAGGAACGGTT
GCGCTGGAGGAACTGCCACGTTCATTCAACCGCCAGCCGGTCTTGCAGCGGTTTGCTATCGTCGCAGCGGGGCCGGTCGC
GAATTTTCTGCTGGCGATCGTCCTTTACTGGCTGTTGTTCATGCTCGGCATCAATGCGATGAAGCCTGTTCTCGGACCTG
TTGCTCCCGCAACTCCGGCGGCATTTGCCGGCCTGGAGAAGGGCGACACCCTGAGGCGAATCGAGGGGGAACCGGTGGAA
ACCTGGCAGGATGCGCGCTGGCTGCTATTGTCCCACGCCGTGGAAAGGTCTCCTGCACTTGCGGTGGAAGTGACCGACAT
CCATGGTCAGACCGGGCTGCGGAGGCTGGATTTGAGCAACATCCAGGCGGATGATCTGGATGGGGAGTTTTTAAAGAAAA
TCGGCCTCAGCAGTTATCAGCCCGAGGTTAAACCCGTCATTTCGCAGGTGATACCCGATAGTGCCGGAAGCCGCGCCGGG
TTACGGCCGGGCGATGAAATCCTGGCAGTCAACGGGCTGAAAATTTCCCTGTGGCAAGACCTGGTGCAACAGGTGCGAGA
TCGGCCGGAATCACCGGTCATGCTGGAAATCCGGCGTGACGGTGCCGTGATCGACAAGGAGGTTGTTCCCGACAGCGTCA
CAGAGAATGGAGAAAAAATCGGGAAAATTGGGATTGCGCCGCGGATTGATTCCGATGAGATCGAAAAGCTGTTGATCGAA
GTACGCTATCCCTTGGGCACGGCTTTTGCCAAGGCGATAAACAAAACCTGGGAAACTTCGAAGTTCACCTTGCAAATGTT
CGGAAAAATGCTGGCAGGTGAGGTGTCCTGGAAGAATGTAAGTGGTCCCATCACTATTGCCGACTATGCAGGAAAATCTG
CCCAGATGGGCCTTTCGCCTTATCTGGGTTTTCTCGCCCTGATCAGTGTCAGTTTGGGCGTATTGAACCTGCTGCCCATT
CCCGTATTGGATGGAGGGCATTTAATGTATTATGTCATCGAAATCGTCAAGGGCAGTCCGCTCTCCGCGAAAGCGATGGA
AATCGGTCAGCAGGTGGGGATGGCACTCTTGTTTGCCCTGATGGCTTTTGCCATTTATAACGACATAAACCGCCTCATCC
CCGGTTAA

Upstream 100 bases:

>100_bases
TCAGTTCCAATTGCGGCTTCCATTTCATCCATGCGAAGATGGAAGACTTCTTTTACTTCCCCGTATCAGAGAGTCTGCCG
GAACGCAGACCTGTAGAAGC

Downstream 100 bases:

>100_bases
AGCATGAAAGTCAGGTATCTGGTCGCGCTTGTTTCTGCTTTGTGCGCTTCGGCTTCATGGGCACGCGAGCCCTTCGAAGT
CAAGGACATCCGGGTGGAAG

Product: peptidase M50 membrane-associated zinc metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MTFLFTIAAFVVALGLLIVFHEFGHYLVARWCGVKVLRFSIGFGHPLMRKQVGKDQTEWVIAAFPLGGYVKMLDEREGTV
ALEELPRSFNRQPVLQRFAIVAAGPVANFLLAIVLYWLLFMLGINAMKPVLGPVAPATPAAFAGLEKGDTLRRIEGEPVE
TWQDARWLLLSHAVERSPALAVEVTDIHGQTGLRRLDLSNIQADDLDGEFLKKIGLSSYQPEVKPVISQVIPDSAGSRAG
LRPGDEILAVNGLKISLWQDLVQQVRDRPESPVMLEIRRDGAVIDKEVVPDSVTENGEKIGKIGIAPRIDSDEIEKLLIE
VRYPLGTAFAKAINKTWETSKFTLQMFGKMLAGEVSWKNVSGPITIADYAGKSAQMGLSPYLGFLALISVSLGVLNLLPI
PVLDGGHLMYYVIEIVKGSPLSAKAMEIGQQVGMALLFALMAFAIYNDINRLIPG

Sequences:

>Translated_455_residues
MTFLFTIAAFVVALGLLIVFHEFGHYLVARWCGVKVLRFSIGFGHPLMRKQVGKDQTEWVIAAFPLGGYVKMLDEREGTV
ALEELPRSFNRQPVLQRFAIVAAGPVANFLLAIVLYWLLFMLGINAMKPVLGPVAPATPAAFAGLEKGDTLRRIEGEPVE
TWQDARWLLLSHAVERSPALAVEVTDIHGQTGLRRLDLSNIQADDLDGEFLKKIGLSSYQPEVKPVISQVIPDSAGSRAG
LRPGDEILAVNGLKISLWQDLVQQVRDRPESPVMLEIRRDGAVIDKEVVPDSVTENGEKIGKIGIAPRIDSDEIEKLLIE
VRYPLGTAFAKAINKTWETSKFTLQMFGKMLAGEVSWKNVSGPITIADYAGKSAQMGLSPYLGFLALISVSLGVLNLLPI
PVLDGGHLMYYVIEIVKGSPLSAKAMEIGQQVGMALLFALMAFAIYNDINRLIPG
>Mature_454_residues
TFLFTIAAFVVALGLLIVFHEFGHYLVARWCGVKVLRFSIGFGHPLMRKQVGKDQTEWVIAAFPLGGYVKMLDEREGTVA
LEELPRSFNRQPVLQRFAIVAAGPVANFLLAIVLYWLLFMLGINAMKPVLGPVAPATPAAFAGLEKGDTLRRIEGEPVET
WQDARWLLLSHAVERSPALAVEVTDIHGQTGLRRLDLSNIQADDLDGEFLKKIGLSSYQPEVKPVISQVIPDSAGSRAGL
RPGDEILAVNGLKISLWQDLVQQVRDRPESPVMLEIRRDGAVIDKEVVPDSVTENGEKIGKIGIAPRIDSDEIEKLLIEV
RYPLGTAFAKAINKTWETSKFTLQMFGKMLAGEVSWKNVSGPITIADYAGKSAQMGLSPYLGFLALISVSLGVLNLLPIP
VLDGGHLMYYVIEIVKGSPLSAKAMEIGQQVGMALLFALMAFAIYNDINRLIPG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=452, Percent_Identity=42.2566371681416, Blast_Score=340, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49811; Mature: 49680

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLFTIAAFVVALGLLIVFHEFGHYLVARWCGVKVLRFSIGFGHPLMRKQVGKDQTEWV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCHHHHHHCCCCCCCEE
IAAFPLGGYVKMLDEREGTVALEELPRSFNRQPVLQRFAIVAAGPVANFLLAIVLYWLLF
EEEECCCCHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MLGINAMKPVLGPVAPATPAAFAGLEKGDTLRRIEGEPVETWQDARWLLLSHAVERSPAL
HHCHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCE
AVEVTDIHGQTGLRRLDLSNIQADDLDGEFLKKIGLSSYQPEVKPVISQVIPDSAGSRAG
EEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCC
LRPGDEILAVNGLKISLWQDLVQQVRDRPESPVMLEIRRDGAVIDKEVVPDSVTENGEKI
CCCCCCEEEECCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCEECHHCCCCCHHCCCHHH
GKIGIAPRIDSDEIEKLLIEVRYPLGTAFAKAINKTWETSKFTLQMFGKMLAGEVSWKNV
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
SGPITIADYAGKSAQMGLSPYLGFLALISVSLGVLNLLPIPVLDGGHLMYYVIEIVKGSP
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCC
LSAKAMEIGQQVGMALLFALMAFAIYNDINRLIPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFLFTIAAFVVALGLLIVFHEFGHYLVARWCGVKVLRFSIGFGHPLMRKQVGKDQTEWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCCHHHHHHCCCCCCCEE
IAAFPLGGYVKMLDEREGTVALEELPRSFNRQPVLQRFAIVAAGPVANFLLAIVLYWLLF
EEEECCCCHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
MLGINAMKPVLGPVAPATPAAFAGLEKGDTLRRIEGEPVETWQDARWLLLSHAVERSPAL
HHCHHHHHHHHCCCCCCCCHHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCE
AVEVTDIHGQTGLRRLDLSNIQADDLDGEFLKKIGLSSYQPEVKPVISQVIPDSAGSRAG
EEEEEECCCCCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCC
LRPGDEILAVNGLKISLWQDLVQQVRDRPESPVMLEIRRDGAVIDKEVVPDSVTENGEKI
CCCCCCEEEECCCEEHHHHHHHHHHHCCCCCCEEEEEECCCCEECHHCCCCCHHCCCHHH
GKIGIAPRIDSDEIEKLLIEVRYPLGTAFAKAINKTWETSKFTLQMFGKMLAGEVSWKNV
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
SGPITIADYAGKSAQMGLSPYLGFLALISVSLGVLNLLPIPVLDGGHLMYYVIEIVKGSP
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCC
LSAKAMEIGQQVGMALLFALMAFAIYNDINRLIPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]