Click here to switch to the map view.

The map label for this gene is argC

Identifier: 82701693

GI number: 82701693

Start: 645222

End: 646250

Strand: Reverse

Name: argC

Synonym: Nmul_A0559

Alternate gene names: 82701693

Gene position: 646250-645222 (Counterclockwise)

Preceding gene: 82701694

Following gene: 82701692

Centisome position: 20.3

GC content: 55.1

Gene sequence:

>1029_bases
ATGCTTAAGATTGGCATCGTAGGTGGAACCGGATATACCGGAGTAGAGTTGCTGCGCATCTTGTCTCAACATCCGGAGGT
GAATATCGAGGCGATTACATCGCGCAAGGAAGCTGGCATGGATGTCGCCCAGTTGTTTCCAAGTCTGCGTGGACGGATAG
AGTTAAAATTTTCCGATCCTGCAGAGGCAAACCTCGAAAAATGCGATGTGGTATTTTTTGCCACTCCGAATGGCATTGCC
ATGAAACAGGTTCCATCCCTGCTCGATGCAGGCGTGCGGATAATTGATCTTGCCGCCGATTTTCGCATCAAGGATATCGC
CGTCTGGGAAAAATGGTATGGAATGCCCCATGCGTGCCCCGAACTGGTTGCGGAGGCGGTCTACGGTCTGCCGGAAATCA
ATCGCGACAGGATAAAGACAGCGCGGCTCATAGCCAATCCCGGCTGCTATCCCACGGCCGTGCAGCTGGGTTTCCTTCCC
CTGGTGGAATCGGGTGCCGCGGATCTGGATCATCTCGTCGCAGACGCGAAATCGGGCGTATCAGGCGCGGGACGCAACGC
GGAAATTCATACCCTTTTTGCTGAGGCAGCGGACAACTTCAAGGCCTATGGAGTATCCGGGCATCGCCATCTCCCCGAGA
TCAGGCAGGGCTTGTCGCAAGCGGCAAAACACCCCGTCGGTCTGACATTCGTACCACACCTCACCCCTATGATTCGCGGC
ATTCATGCCACGCTTTATGTAAAACTCCTTAAAGAAGTCGACTTGCAGGCGTTATATGAAAACCGCTACGTGAATGAACC
GTTTGTCGACGTGCTTCCGGCAGGCTCCCATCCGGAAACCCGCTCCGTGCGGGGTTCGAATCTCTGCCGCATCGCCGTCC
ATCGACCCCAGGGGGGGGATACGGCCGTCATACTCTCGGTTACAGACAACCTTGTCAAGGGTGCGGCCGGACAGGCAGTG
CAGAATATGAATCTCATGTTCGGCTTGCCGGAAACCCTTGCCATCACCCATCTTCCCTTGTTTCCGTAA

Upstream 100 bases:

>100_bases
CTGGCGCTTGTAATCGCAAAACCTTCCACAGACATCATGTGGATGTCAGGTAGATGCAGCGTGCCAACGAATTTCAACCA
CACGAAAATTTAGAAGAACC

Downstream 100 bases:

>100_bases
GAATCTAAACAAGCGTACGGAGCTGCGTTGCTGCCGAAATCAGTCCAGGCGCCCTCAAGAAGATCCCGCCATGCAATGAG
AGTTAATTTCCAGAAAATGC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLKIGIVGGTGYTGVELLRILSQHPEVNIEAITSRKEAGMDVAQLFPSLRGRIELKFSDPAEANLEKCDVVFFATPNGIA
MKQVPSLLDAGVRIIDLAADFRIKDIAVWEKWYGMPHACPELVAEAVYGLPEINRDRIKTARLIANPGCYPTAVQLGFLP
LVESGAADLDHLVADAKSGVSGAGRNAEIHTLFAEAADNFKAYGVSGHRHLPEIRQGLSQAAKHPVGLTFVPHLTPMIRG
IHATLYVKLLKEVDLQALYENRYVNEPFVDVLPAGSHPETRSVRGSNLCRIAVHRPQGGDTAVILSVTDNLVKGAAGQAV
QNMNLMFGLPETLAITHLPLFP

Sequences:

>Translated_342_residues
MLKIGIVGGTGYTGVELLRILSQHPEVNIEAITSRKEAGMDVAQLFPSLRGRIELKFSDPAEANLEKCDVVFFATPNGIA
MKQVPSLLDAGVRIIDLAADFRIKDIAVWEKWYGMPHACPELVAEAVYGLPEINRDRIKTARLIANPGCYPTAVQLGFLP
LVESGAADLDHLVADAKSGVSGAGRNAEIHTLFAEAADNFKAYGVSGHRHLPEIRQGLSQAAKHPVGLTFVPHLTPMIRG
IHATLYVKLLKEVDLQALYENRYVNEPFVDVLPAGSHPETRSVRGSNLCRIAVHRPQGGDTAVILSVTDNLVKGAAGQAV
QNMNLMFGLPETLAITHLPLFP
>Mature_342_residues
MLKIGIVGGTGYTGVELLRILSQHPEVNIEAITSRKEAGMDVAQLFPSLRGRIELKFSDPAEANLEKCDVVFFATPNGIA
MKQVPSLLDAGVRIIDLAADFRIKDIAVWEKWYGMPHACPELVAEAVYGLPEINRDRIKTARLIANPGCYPTAVQLGFLP
LVESGAADLDHLVADAKSGVSGAGRNAEIHTLFAEAADNFKAYGVSGHRHLPEIRQGLSQAAKHPVGLTFVPHLTPMIRG
IHATLYVKLLKEVDLQALYENRYVNEPFVDVLPAGSHPETRSVRGSNLCRIAVHRPQGGDTAVILSVTDNLVKGAAGQAV
QNMNLMFGLPETLAITHLPLFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=38.5507246376812, Blast_Score=209, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320913, Length=345, Percent_Identity=29.2753623188406, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_NITMU (Q2YBK4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411259.1
- HSSP:   Q9X2A2
- ProteinModelPortal:   Q2YBK4
- STRING:   Q2YBK4
- GeneID:   3784779
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0559
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- PhylomeDB:   Q2YBK4
- ProtClustDB:   PRK00436
- BioCyc:   NMUL323848:NMUL_A0559-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37012; Mature: 37012

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIGIVGGTGYTGVELLRILSQHPEVNIEAITSRKEAGMDVAQLFPSLRGRIELKFSDP
CEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHHCCHHHHHHHHHCCEEEEEECCC
AEANLEKCDVVFFATPNGIAMKQVPSLLDAGVRIIDLAADFRIKDIAVWEKWYGMPHACP
CCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCEEHHHHHHHHHCCCCCCCH
ELVAEAVYGLPEINRDRIKTARLIANPGCYPTAVQLGFLPLVESGAADLDHLVADAKSGV
HHHHHHHHCCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
SGAGRNAEIHTLFAEAADNFKAYGVSGHRHLPEIRQGLSQAAKHPVGLTFVPHLTPMIRG
CCCCCCCEEEEEEHHHCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
IHATLYVKLLKEVDLQALYENRYVNEPFVDVLPAGSHPETRSVRGSNLCRIAVHRPQGGD
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCCCCCCCCCCCCCCEEEEEEECCCCCC
TAVILSVTDNLVKGAAGQAVQNMNLMFGLPETLAITHLPLFP
EEEEEEECHHHHHCCCCHHHHCCCEEECCCHHHHEECCCCCC
>Mature Secondary Structure
MLKIGIVGGTGYTGVELLRILSQHPEVNIEAITSRKEAGMDVAQLFPSLRGRIELKFSDP
CEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCHHHHCCHHHHHHHHHCCEEEEEECCC
AEANLEKCDVVFFATPNGIAMKQVPSLLDAGVRIIDLAADFRIKDIAVWEKWYGMPHACP
CCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCEEHHHHHHHHHCCCCCCCH
ELVAEAVYGLPEINRDRIKTARLIANPGCYPTAVQLGFLPLVESGAADLDHLVADAKSGV
HHHHHHHHCCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
SGAGRNAEIHTLFAEAADNFKAYGVSGHRHLPEIRQGLSQAAKHPVGLTFVPHLTPMIRG
CCCCCCCEEEEEEHHHCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
IHATLYVKLLKEVDLQALYENRYVNEPFVDVLPAGSHPETRSVRGSNLCRIAVHRPQGGD
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEECCCCCCCCCCCCCCCEEEEEEECCCCCC
TAVILSVTDNLVKGAAGQAVQNMNLMFGLPETLAITHLPLFP
EEEEEEECHHHHHCCCCHHHHCCCEEECCCHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA