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The map label for this gene is ctaD [H]

Identifier: 82701593

GI number: 82701593

Start: 508790

End: 510805

Strand: Reverse

Name: ctaD [H]

Synonym: Nmul_A0459

Alternate gene names: 82701593

Gene position: 510805-508790 (Counterclockwise)

Preceding gene: 82701594

Following gene: 82701592

Centisome position: 16.04

GC content: 57.04

Gene sequence:

>2016_bases
ATGGCTGCTATCGACGCCACCCGGCATCGCATCGACCCCCCTCTCGAACGGATCCCGGAAGTGGGACGTATTCCCGCGGG
GTCCCCAATCGAAGCGCGTCTGGAGAAGATCTGGGAGACGGCGCCAGGTTGGCGCGGATGGCTCTCCACAGTAGACCATA
AAACGATCGGAGTACGATATCTCGTCACGGCCTTTCTTTTCCTCGTGATCGGCGGAATCGAAGCGCTGTTCCTGCGCATC
CAGCTTGCCGGGCCGGATATGGCGTTTCTGACACCGGAGCAATACAACCAGCTTTTCACGATGCATGGCGTGACCATGAT
TTTCCTCTATGCATTGCCGGTTCTGTCCGGTTTCTCCAACTACCTCTGGCCGCTTTTGCTCGGTTCCAGGGATATGGCCT
TTCCGCGCCTCAATGCACTCTCCTACTGGATTTTTCTGTTCGCCGGCCTCTTCATGTACATCAGCTTCCCTCTGGGGCAG
GCGCCGAATGCGGGCTGGTTCAATTATGTGCCTTTCTCGGGCCCGGTATACAACACCGGACCCAATATCGACGTCTTTGC
GCTCGGCATGGTGTTGCTCGGAATTTCCACAACGGTAGGGTCGGTTAATTTCGTGGTTACGCTGTTCAGGATGCGGGCGC
CGGGCATGACCATAAACCGCGTTCCCATCCTGGTGTGGGGAACGCTCACCGCGTCCGTGGCCAACCTGTTCGCAATCCCC
GCCGTCAGCCTCGCGTTCTTTCTGTTGTGGCTTGATCGCCAGATAGGCGCGCATTTTTTTGATGTCGCAAATAACGGTCA
GCCATTGCTTTGGCAGCACTTGTTCTGGATTTTCGGCCATCCCTGGGTCTATGTCGTCGTGCTTCCGGCAATGGGCATCG
TTTCCGATGCCCTGCCTACATTCTGTCGCCGGCCGCTCGTGGGTTACACGGCAGTGGCGCTAGCTACCATGGCAACCATG
CTGCTCGGTTTCGGGGTGTGGGTCCATCATATGTTCGCCACCGGTCTGCCGACAGTGGCTCTGTCGATTTTCGGCGCCGC
CAGCATGGTCATCTCCATTCCCAGCGCGGTCGCCGTCTTCGCCTGGATTGCGACCATCTGGCTGGGAAAACCCGTATTCA
AGACCCCTTTTCTGTTTTTTGCCGGTTTCGTCGCGCTGTTCATCATCGGCGGCATGTCGGGAGTAATGACAGCCGCGGTG
CCGCTCGACTGGCAGCTTAACGAAACCTACTTCATCGTGGCGCACCTGCATTATGTCCTGCTTGGGATCAACGTGTTTCC
GGTGGTAGGAGCGATCTATTACTGGTTTCCCAAATTCACCGGGCGCATGATGAGTGAAAAACTGGGCAAGTGGAGTTTCT
GGACCATGTTTATCGGATTCAACGCCGGATTCTTTCCAATGCATATCGCTGGACTGCTCGGGATGCCGCGCCGCATTTAT
ACCTATCCTTCCCGCATGGGATGGGACGAAGTCAACCTGATTACGACTGTCGGATCCTTCATATTCGCCGTTGGCGTGCT
GATCTTCCTCGTCAATGTCGTCCTCAGCCTGAAACGTGGAACCCGGGCGGGCGCCAATCCGTGGGATGCGCCGACCCTGG
AATGGGCAGTATCTTCCCCGCCGCCCGCTTATAACTTTGCGACTATTCCTACGATCGCCAGCCGGCACCCGTTATGGGAG
GGGCGGATCGAAGGAGAAAAAGAACATACCCGGACTAGATTGGAAGAAGGTTACCTGCTGATGCGGGGCCGGGAAACACT
CGGCACCTCGCCCATCGATGCAAAGCCGGTTGTCATCCTCAAAATGCCGGAGGATTCCTATACCCCTTTCCTTGTCGGTT
TGTTCGTCTCGTTGCTATTCGTCGGCCTGTTGCTGCATTCATGGACATTCACTGCATTGATGGCGGCCTTAAGCTGTGCC
GCGTTGAGTGTCTGGATGTGGCCGCGCAGGAACCTGGGTCAGCGTACTGCCAGGCACGACCCAGCCTCTGCCCGAAGAGG
AGGAAAAGGCCCGTGA

Upstream 100 bases:

>100_bases
ATACTTCAAGCCGGGAGCACGCATGCCAAGTATTGCATTATCGGACAGTGAAGCTTCAGCACTGGCCTCCTATCTTTCGA
CACTGGACTAGAACTAGAGT

Downstream 100 bases:

>100_bases
GCGGGACTGCCCCCGTTGTCACCCCTTTGCCGGTGGGAAGCGCTGGTAAGCTCTCCGGCGGATGGTGGGGAGTGATCGCG
CTCATCGTGACCGAGGCTTC

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MAAIDATRHRIDPPLERIPEVGRIPAGSPIEARLEKIWETAPGWRGWLSTVDHKTIGVRYLVTAFLFLVIGGIEALFLRI
QLAGPDMAFLTPEQYNQLFTMHGVTMIFLYALPVLSGFSNYLWPLLLGSRDMAFPRLNALSYWIFLFAGLFMYISFPLGQ
APNAGWFNYVPFSGPVYNTGPNIDVFALGMVLLGISTTVGSVNFVVTLFRMRAPGMTINRVPILVWGTLTASVANLFAIP
AVSLAFFLLWLDRQIGAHFFDVANNGQPLLWQHLFWIFGHPWVYVVVLPAMGIVSDALPTFCRRPLVGYTAVALATMATM
LLGFGVWVHHMFATGLPTVALSIFGAASMVISIPSAVAVFAWIATIWLGKPVFKTPFLFFAGFVALFIIGGMSGVMTAAV
PLDWQLNETYFIVAHLHYVLLGINVFPVVGAIYYWFPKFTGRMMSEKLGKWSFWTMFIGFNAGFFPMHIAGLLGMPRRIY
TYPSRMGWDEVNLITTVGSFIFAVGVLIFLVNVVLSLKRGTRAGANPWDAPTLEWAVSSPPPAYNFATIPTIASRHPLWE
GRIEGEKEHTRTRLEEGYLLMRGRETLGTSPIDAKPVVILKMPEDSYTPFLVGLFVSLLFVGLLLHSWTFTALMAALSCA
ALSVWMWPRRNLGQRTARHDPASARRGGKGP

Sequences:

>Translated_671_residues
MAAIDATRHRIDPPLERIPEVGRIPAGSPIEARLEKIWETAPGWRGWLSTVDHKTIGVRYLVTAFLFLVIGGIEALFLRI
QLAGPDMAFLTPEQYNQLFTMHGVTMIFLYALPVLSGFSNYLWPLLLGSRDMAFPRLNALSYWIFLFAGLFMYISFPLGQ
APNAGWFNYVPFSGPVYNTGPNIDVFALGMVLLGISTTVGSVNFVVTLFRMRAPGMTINRVPILVWGTLTASVANLFAIP
AVSLAFFLLWLDRQIGAHFFDVANNGQPLLWQHLFWIFGHPWVYVVVLPAMGIVSDALPTFCRRPLVGYTAVALATMATM
LLGFGVWVHHMFATGLPTVALSIFGAASMVISIPSAVAVFAWIATIWLGKPVFKTPFLFFAGFVALFIIGGMSGVMTAAV
PLDWQLNETYFIVAHLHYVLLGINVFPVVGAIYYWFPKFTGRMMSEKLGKWSFWTMFIGFNAGFFPMHIAGLLGMPRRIY
TYPSRMGWDEVNLITTVGSFIFAVGVLIFLVNVVLSLKRGTRAGANPWDAPTLEWAVSSPPPAYNFATIPTIASRHPLWE
GRIEGEKEHTRTRLEEGYLLMRGRETLGTSPIDAKPVVILKMPEDSYTPFLVGLFVSLLFVGLLLHSWTFTALMAALSCA
ALSVWMWPRRNLGQRTARHDPASARRGGKGP
>Mature_670_residues
AAIDATRHRIDPPLERIPEVGRIPAGSPIEARLEKIWETAPGWRGWLSTVDHKTIGVRYLVTAFLFLVIGGIEALFLRIQ
LAGPDMAFLTPEQYNQLFTMHGVTMIFLYALPVLSGFSNYLWPLLLGSRDMAFPRLNALSYWIFLFAGLFMYISFPLGQA
PNAGWFNYVPFSGPVYNTGPNIDVFALGMVLLGISTTVGSVNFVVTLFRMRAPGMTINRVPILVWGTLTASVANLFAIPA
VSLAFFLLWLDRQIGAHFFDVANNGQPLLWQHLFWIFGHPWVYVVVLPAMGIVSDALPTFCRRPLVGYTAVALATMATML
LGFGVWVHHMFATGLPTVALSIFGAASMVISIPSAVAVFAWIATIWLGKPVFKTPFLFFAGFVALFIIGGMSGVMTAAVP
LDWQLNETYFIVAHLHYVLLGINVFPVVGAIYYWFPKFTGRMMSEKLGKWSFWTMFIGFNAGFFPMHIAGLLGMPRRIYT
YPSRMGWDEVNLITTVGSFIFAVGVLIFLVNVVLSLKRGTRAGANPWDAPTLEWAVSSPPPAYNFATIPTIASRHPLWEG
RIEGEKEHTRTRLEEGYLLMRGRETLGTSPIDAKPVVILKMPEDSYTPFLVGLFVSLLFVGLLLHSWTFTALMAALSCAA
LSVWMWPRRNLGQRTARHDPASARRGGKGP

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=504, Percent_Identity=36.7063492063492, Blast_Score=319, Evalue=5e-87,
Organism=Escherichia coli, GI1786634, Length=591, Percent_Identity=34.8561759729272, Blast_Score=385, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6226519, Length=536, Percent_Identity=34.8880597014925, Blast_Score=330, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6226524, Length=322, Percent_Identity=35.0931677018634, Blast_Score=219, Evalue=9e-58,
Organism=Saccharomyces cerevisiae, GI6226523, Length=244, Percent_Identity=32.3770491803279, Blast_Score=137, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 74506; Mature: 74375

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAIDATRHRIDPPLERIPEVGRIPAGSPIEARLEKIWETAPGWRGWLSTVDHKTIGVRY
CCCCCCHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHH
LVTAFLFLVIGGIEALFLRIQLAGPDMAFLTPEQYNQLFTMHGVTMIFLYALPVLSGFSN
HHHHHHHHHHHHHHHHHEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLWPLLLGSRDMAFPRLNALSYWIFLFAGLFMYISFPLGQAPNAGWFNYVPFSGPVYNTG
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCC
PNIDVFALGMVLLGISTTVGSVNFVVTLFRMRAPGMTINRVPILVWGTLTASVANLFAIP
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEECCCCEEEEHHHHHHHHHHHHHH
AVSLAFFLLWLDRQIGAHFFDVANNGQPLLWQHLFWIFGHPWVYVVVLPAMGIVSDALPT
HHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FCRRPLVGYTAVALATMATMLLGFGVWVHHMFATGLPTVALSIFGAASMVISIPSAVAVF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
AWIATIWLGKPVFKTPFLFFAGFVALFIIGGMSGVMTAAVPLDWQLNETYFIVAHLHYVL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCEEECCCEEHHHHHHHHH
LGINVFPVVGAIYYWFPKFTGRMMSEKLGKWSFWTMFIGFNAGFFPMHIAGLLGMPRRIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHEE
TYPSRMGWDEVNLITTVGSFIFAVGVLIFLVNVVLSLKRGTRAGANPWDAPTLEWAVSSP
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
PPAYNFATIPTIASRHPLWEGRIEGEKEHTRTRLEEGYLLMRGRETLGTSPIDAKPVVIL
CCCCCCEECCCHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCHHCCCCCCCCCCEEEE
KMPEDSYTPFLVGLFVSLLFVGLLLHSWTFTALMAALSCAALSVWMWPRRNLGQRTARHD
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
PASARRGGKGP
CHHHCCCCCCC
>Mature Secondary Structure 
AAIDATRHRIDPPLERIPEVGRIPAGSPIEARLEKIWETAPGWRGWLSTVDHKTIGVRY
CCCCCHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHH
LVTAFLFLVIGGIEALFLRIQLAGPDMAFLTPEQYNQLFTMHGVTMIFLYALPVLSGFSN
HHHHHHHHHHHHHHHHHEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLWPLLLGSRDMAFPRLNALSYWIFLFAGLFMYISFPLGQAPNAGWFNYVPFSGPVYNTG
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCC
PNIDVFALGMVLLGISTTVGSVNFVVTLFRMRAPGMTINRVPILVWGTLTASVANLFAIP
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEECCCCEEEEHHHHHHHHHHHHHH
AVSLAFFLLWLDRQIGAHFFDVANNGQPLLWQHLFWIFGHPWVYVVVLPAMGIVSDALPT
HHHHHHHHHHHHHHHCCHHEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FCRRPLVGYTAVALATMATMLLGFGVWVHHMFATGLPTVALSIFGAASMVISIPSAVAVF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
AWIATIWLGKPVFKTPFLFFAGFVALFIIGGMSGVMTAAVPLDWQLNETYFIVAHLHYVL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCEEECCCEEHHHHHHHHH
LGINVFPVVGAIYYWFPKFTGRMMSEKLGKWSFWTMFIGFNAGFFPMHIAGLLGMPRRIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHCCCHHEE
TYPSRMGWDEVNLITTVGSFIFAVGVLIFLVNVVLSLKRGTRAGANPWDAPTLEWAVSSP
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCC
PPAYNFATIPTIASRHPLWEGRIEGEKEHTRTRLEEGYLLMRGRETLGTSPIDAKPVVIL
CCCCCCEECCCHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCHHCCCCCCCCCCEEEE
KMPEDSYTPFLVGLFVSLLFVGLLLHSWTFTALMAALSCAALSVWMWPRRNLGQRTARHD
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
PASARRGGKGP
CHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]