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The map label for this gene is hfq

Identifier: 82701581

GI number: 82701581

Start: 496699

End: 496944

Strand: Reverse

Name: hfq

Synonym: Nmul_A0447

Alternate gene names: 82701581

Gene position: 496944-496699 (Counterclockwise)

Preceding gene: 82701582

Following gene: 82701580

Centisome position: 15.61

GC content: 46.75

Gene sequence:

>246_bases
ATGAGCGCTAAAGGGCAATTGTTACAAGACCCGTTTCTGAATACCTTGCGGAAGGAACATATTCCGGTTTCGATTTATCT
GGTAAACGGAATCAAACTGCAGGGGCACATCGATTCATTCGATCAGTATGTAGTGCTGTTGAAGAATACCGTCACCCAGA
TGGTCTACAAGCACGCAATTTCTACGGTAGTCCCCGCAAGAGCCGTCAACATTCCATTTGAGGCGCCCCCTATATCTGAT
GCTTGA

Upstream 100 bases:

>100_bases
TGCCCGATTCGGCCTTCAACGGACCTCAGCAGGAATATGGATTTACGCTTCAAAATCAAGTAGAGTTTATTTTTTGAATA
ATTAAAACACGGAGTCACGT

Downstream 100 bases:

>100_bases
TTCCTCTAGTGGGAACGCGCCCGACACTCACGCCGCTGTTGATTCTGCTGTTCTGGTAAGTCTCGATCTAAATGACAGCG
ACTCTGCAGAAAATCTCGAA

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 81; Mature: 80

Protein sequence:

>81_residues
MSAKGQLLQDPFLNTLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLKNTVTQMVYKHAISTVVPARAVNIPFEAPPISD
A

Sequences:

>Translated_81_residues
MSAKGQLLQDPFLNTLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLKNTVTQMVYKHAISTVVPARAVNIPFEAPPISD
A
>Mature_80_residues
SAKGQLLQDPFLNTLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLKNTVTQMVYKHAISTVVPARAVNIPFEAPPISDA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=68, Percent_Identity=80.8823529411765, Blast_Score=119, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_NITMU (Q2YBW6)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411147.1
- ProteinModelPortal:   Q2YBW6
- SMR:   Q2YBW6
- STRING:   Q2YBW6
- GeneID:   3785915
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0447
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- PhylomeDB:   Q2YBW6
- ProtClustDB:   PRK00395
- BioCyc:   NMUL323848:NMUL_A0447-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9002; Mature: 8870

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKGQLLQDPFLNTLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLKNTVTQMVYKHAI
CCCCCCCCCCHHHHHHHHCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
STVVPARAVNIPFEAPPISDA
HHHCCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
SAKGQLLQDPFLNTLRKEHIPVSIYLVNGIKLQGHIDSFDQYVVLLKNTVTQMVYKHAI
CCCCCCCCCHHHHHHHHCCCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
STVVPARAVNIPFEAPPISDA
HHHCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA