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The map label for this gene is hflK [H]

Identifier: 82701579

GI number: 82701579

Start: 494218

End: 495417

Strand: Reverse

Name: hflK [H]

Synonym: Nmul_A0445

Alternate gene names: 82701579

Gene position: 495417-494218 (Counterclockwise)

Preceding gene: 82701580

Following gene: 82701578

Centisome position: 15.56

GC content: 54.92

Gene sequence:

>1200_bases
ATGGGATTAAATGATCCTCAGTGGGGAAGAAAAAAAGGCAATTCCGGTCCACCCGATCTGGATCAATTGTGGCGAAATTT
TAACAAGAAGCTCAACAACCTTTTGAAGCGCAAGGGTGGAGGAAGGCGCGACAGTTCAGGAGGGGGTGAAGGCGCCCCCC
CGGCCGGTCCCAAAAAATACAGTGGGGGCGCCGGCCTGCTTGCCGGATTGCTTCTGCTGTTGTGGATAGGAAGCGGATTT
TATATCGTCAACGAGGGCCAGCGCGGTATCGTGTTGCGGTTCGGAAAATATGTGGAGAGTACGCAGGCAGGCTTGCGCTG
GCATCTGCCCTATCCTATCGAGGTCGTTGAACCCGTTAACGTAAGCCAGGTGCGGACTGTTGAAATCGGCTATCGTAACA
ATGTCCGGAGCAAGGTGCTGAAGGAGTCGCTCATGTTGACCGACGACGAGAACATCATTGATATTCAGTTCGCCGTGCAA
TACATCCTGAAAAATCCGGAGGACTTCCTGTTCACCAATCGTGACCCCGAAAACGCCGTGCTGCAAGCAGCGGAAACCGC
GATACGGGAAATCATCGGAAAGAGCAAGATGGACTTCGTGCTCTATGAAGGGCGTGAACAAGTGGCGGCAAAAGCCACGG
AGCTGATGCAGGACATCCTTGATCGCTACAAGATTGGCATCGCCATCAGCAAAGTGACGATGCAGAACGCCCAACCGCCC
GAACAGGTCCAGGCGGCGTTCGATGATGCCGTCAAAGCCGGACAGGATAGGGAACGGCAGAAAAACGAAGGCCAGGCCTA
TGCGAATGACGTGATTCCCAAGGCCAAAGGTAATGCGGCCCGCCTCCTCGAAGAGGCTGAGGGGTACAAGCAACGGGTGA
TTGCGAGTTCGGAAGGTGAGGCGAGCCGCTTCAAGCAGGTTCTCGTTGAATACAGCAAGGCACCGGGTGTGACGCGTGAC
CGGCTTTATCTGGATATGATGGAGCAGGTGCTTTCCAACACAAGCAAAGTTATCGTGGACCAGAAAAATGGCAATAACCT
TCTTTATCTGCCGTTGGACAAGCTCATACAGATGAGCGGGCCTTCTTCCTCCTCTGGCACAGTGCCGGAGACACAGCTTG
CGTCGCCGCCGGAACCTACGGCCGATGCCGCTACCCGCACCCGGGAAGCATTTCGTGGCCGCGAACGGGAGACAAGATAA

Upstream 100 bases:

>100_bases
CGAATAACGCAGGAATTTTTGCTTTCCACAAATCTGGTTCGGGTTTTTTCACGGTAGAGTTTGATGGTCTGCTCCATTAA
ACAAAAAAATAGGAATCATC

Downstream 100 bases:

>100_bases
GTGAAAAACTATACTCCAATGTTATTGACTGTCCTTATCATCCTGTTTCTTGTGGCAAGCTCGTCACTGTATATAGTCGA
CCAGCGGCAGCAGGCGATTC

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MGLNDPQWGRKKGNSGPPDLDQLWRNFNKKLNNLLKRKGGGRRDSSGGGEGAPPAGPKKYSGGAGLLAGLLLLLWIGSGF
YIVNEGQRGIVLRFGKYVESTQAGLRWHLPYPIEVVEPVNVSQVRTVEIGYRNNVRSKVLKESLMLTDDENIIDIQFAVQ
YILKNPEDFLFTNRDPENAVLQAAETAIREIIGKSKMDFVLYEGREQVAAKATELMQDILDRYKIGIAISKVTMQNAQPP
EQVQAAFDDAVKAGQDRERQKNEGQAYANDVIPKAKGNAARLLEEAEGYKQRVIASSEGEASRFKQVLVEYSKAPGVTRD
RLYLDMMEQVLSNTSKVIVDQKNGNNLLYLPLDKLIQMSGPSSSSGTVPETQLASPPEPTADAATRTREAFRGRERETR

Sequences:

>Translated_399_residues
MGLNDPQWGRKKGNSGPPDLDQLWRNFNKKLNNLLKRKGGGRRDSSGGGEGAPPAGPKKYSGGAGLLAGLLLLLWIGSGF
YIVNEGQRGIVLRFGKYVESTQAGLRWHLPYPIEVVEPVNVSQVRTVEIGYRNNVRSKVLKESLMLTDDENIIDIQFAVQ
YILKNPEDFLFTNRDPENAVLQAAETAIREIIGKSKMDFVLYEGREQVAAKATELMQDILDRYKIGIAISKVTMQNAQPP
EQVQAAFDDAVKAGQDRERQKNEGQAYANDVIPKAKGNAARLLEEAEGYKQRVIASSEGEASRFKQVLVEYSKAPGVTRD
RLYLDMMEQVLSNTSKVIVDQKNGNNLLYLPLDKLIQMSGPSSSSGTVPETQLASPPEPTADAATRTREAFRGRERETR
>Mature_398_residues
GLNDPQWGRKKGNSGPPDLDQLWRNFNKKLNNLLKRKGGGRRDSSGGGEGAPPAGPKKYSGGAGLLAGLLLLLWIGSGFY
IVNEGQRGIVLRFGKYVESTQAGLRWHLPYPIEVVEPVNVSQVRTVEIGYRNNVRSKVLKESLMLTDDENIIDIQFAVQY
ILKNPEDFLFTNRDPENAVLQAAETAIREIIGKSKMDFVLYEGREQVAAKATELMQDILDRYKIGIAISKVTMQNAQPPE
QVQAAFDDAVKAGQDRERQKNEGQAYANDVIPKAKGNAARLLEEAEGYKQRVIASSEGEASRFKQVLVEYSKAPGVTRDR
LYLDMMEQVLSNTSKVIVDQKNGNNLLYLPLDKLIQMSGPSSSSGTVPETQLASPPEPTADAATRTREAFRGRERETR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=301, Percent_Identity=40.1993355481728, Blast_Score=235, Evalue=4e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 44210; Mature: 44078

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLNDPQWGRKKGNSGPPDLDQLWRNFNKKLNNLLKRKGGGRRDSSGGGEGAPPAGPKKY
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SGGAGLLAGLLLLLWIGSGFYIVNEGQRGIVLRFGKYVESTQAGLRWHLPYPIEVVEPVN
CCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHHHHHCCCEECCCCCCEEECCCC
VSQVRTVEIGYRNNVRSKVLKESLMLTDDENIIDIQFAVQYILKNPEDFLFTNRDPENAV
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCHHHEECCCCCHHHH
LQAAETAIREIIGKSKMDFVLYEGREQVAAKATELMQDILDRYKIGIAISKVTMQNAQPP
HHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCH
EQVQAAFDDAVKAGQDRERQKNEGQAYANDVIPKAKGNAARLLEEAEGYKQRVIASSEGE
HHHHHHHHHHHHCCCHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCH
ASRFKQVLVEYSKAPGVTRDRLYLDMMEQVLSNTSKVIVDQKNGNNLLYLPLDKLIQMSG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECHHHHHHCCC
PSSSSGTVPETQLASPPEPTADAATRTREAFRGRERETR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GLNDPQWGRKKGNSGPPDLDQLWRNFNKKLNNLLKRKGGGRRDSSGGGEGAPPAGPKKY
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
SGGAGLLAGLLLLLWIGSGFYIVNEGQRGIVLRFGKYVESTQAGLRWHLPYPIEVVEPVN
CCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHHHHHHHHCCCEECCCCCCEEECCCC
VSQVRTVEIGYRNNVRSKVLKESLMLTDDENIIDIQFAVQYILKNPEDFLFTNRDPENAV
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCHHHEECCCCCHHHH
LQAAETAIREIIGKSKMDFVLYEGREQVAAKATELMQDILDRYKIGIAISKVTMQNAQPP
HHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHCCCCCH
EQVQAAFDDAVKAGQDRERQKNEGQAYANDVIPKAKGNAARLLEEAEGYKQRVIASSEGE
HHHHHHHHHHHHCCCHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCH
ASRFKQVLVEYSKAPGVTRDRLYLDMMEQVLSNTSKVIVDQKNGNNLLYLPLDKLIQMSG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECHHHHHHCCC
PSSSSGTVPETQLASPPEPTADAATRTREAFRGRERETR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]