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The map label for this gene is rpiA

Identifier: 82701570

GI number: 82701570

Start: 483842

End: 484501

Strand: Reverse

Name: rpiA

Synonym: Nmul_A0436

Alternate gene names: 82701570

Gene position: 484501-483842 (Counterclockwise)

Preceding gene: 82701574

Following gene: 82701569

Centisome position: 15.22

GC content: 56.06

Gene sequence:

>660_bases
ATGAATCAGGACGAGCAGAAACGGGCGGCCGCGCACGCCGCTATTCAACATATTCCCGCAGGCTGTATTGTCGGAGTCGG
CACCGGCTCTACCGCCAACTACTTCATAGACGCACTGGCCGGCATCAGAAGCAGGATCGATGGAGCGGTAGCGAGTTCAG
AAGCAACCGCCCGGCGGCTCAGCGCACATGGAATCGAGGTCATGGACCTTAATAATGTCGACGAGCTTCCGTTATATGTG
GATGGCGCTGATGAGATAACGCCGCATCTGCATATGATAAAAGGGGGTGGCGGAGCTCTGACCCGGGAAAAAATCGTGGC
CGCCGTGGCGAAAAAATTTATCTGCATTGCGGACCAGAGCAAGCTCGTGGACGTGCTTGGCAAGTTTCCGCTGCCCGTGG
AGGTTATCCCGATGGCGCGCGGTCACGTGGCGCGCGAGATAGTACGGCTGGGGGGACAACCCATGCTCAGGCAGGGATTT
ACCACTGATAACGGTAACGTCATTCTTGATGTGCACGCCTTGCAGATCCTGAACCCCATTGAACTGGAGACGGAACTCAA
TCAGATCACCGGCATCGTAACCAATGGCCTGTTTGCAAGACGCCCTGCGGATTTGCTGTTGCTGGGAGACGAAGGAGGCA
TTCGTACCATTGCTATCTGA

Upstream 100 bases:

>100_bases
ACATGTCGCGAAACGCTAAATGCCCAGCTTCATTGTTAAAATGGGCTGATAGTATTATGCTCATAAACAATCAATATTTT
CAGACATAAAAAATAACATC

Downstream 100 bases:

>100_bases
AGGAAGGCCAAAGATCAGTAGAATTGTCACAACGGACTGATATTATCCTTTGTTATTTTTTGCTTTCAATCGATCCACAG
GTGAGAAATGGGAAGCCACG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MNQDEQKRAAAHAAIQHIPAGCIVGVGTGSTANYFIDALAGIRSRIDGAVASSEATARRLSAHGIEVMDLNNVDELPLYV
DGADEITPHLHMIKGGGGALTREKIVAAVAKKFICIADQSKLVDVLGKFPLPVEVIPMARGHVAREIVRLGGQPMLRQGF
TTDNGNVILDVHALQILNPIELETELNQITGIVTNGLFARRPADLLLLGDEGGIRTIAI

Sequences:

>Translated_219_residues
MNQDEQKRAAAHAAIQHIPAGCIVGVGTGSTANYFIDALAGIRSRIDGAVASSEATARRLSAHGIEVMDLNNVDELPLYV
DGADEITPHLHMIKGGGGALTREKIVAAVAKKFICIADQSKLVDVLGKFPLPVEVIPMARGHVAREIVRLGGQPMLRQGF
TTDNGNVILDVHALQILNPIELETELNQITGIVTNGLFARRPADLLLLGDEGGIRTIAI
>Mature_219_residues
MNQDEQKRAAAHAAIQHIPAGCIVGVGTGSTANYFIDALAGIRSRIDGAVASSEATARRLSAHGIEVMDLNNVDELPLYV
DGADEITPHLHMIKGGGGALTREKIVAAVAKKFICIADQSKLVDVLGKFPLPVEVIPMARGHVAREIVRLGGQPMLRQGF
TTDNGNVILDVHALQILNPIELETELNQITGIVTNGLFARRPADLLLLGDEGGIRTIAI

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=212, Percent_Identity=36.3207547169811, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=63.1336405529954, Blast_Score=282, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17551758, Length=230, Percent_Identity=34.7826086956522, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324669, Length=221, Percent_Identity=29.8642533936652, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281364072, Length=194, Percent_Identity=34.5360824742268, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_NITMU (Q2YBX7)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411136.1
- ProteinModelPortal:   Q2YBX7
- SMR:   Q2YBX7
- STRING:   Q2YBX7
- GeneID:   3785904
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0436
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   DKSIVGV
- PhylomeDB:   Q2YBX7
- ProtClustDB:   PRK00702
- BioCyc:   NMUL323848:NMUL_A0436-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23261; Mature: 23261

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQDEQKRAAAHAAIQHIPAGCIVGVGTGSTANYFIDALAGIRSRIDGAVASSEATARRL
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHH
SAHGIEVMDLNNVDELPLYVDGADEITPHLHMIKGGGGALTREKIVAAVAKKFICIADQS
HHCCEEEEECCCCCCCCEEECCCHHCCCCEEEEECCCCCHHHHHHHHHHHHHHEEECCCH
KLVDVLGKFPLPVEVIPMARGHVAREIVRLGGQPMLRQGFTTDNGNVILDVHALQILNPI
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEHHHHHCCCH
ELETELNQITGIVTNGLFARRPADLLLLGDEGGIRTIAI
HHHHHHHHHHHHHHCCEECCCCCCEEEECCCCCEEEEEC
>Mature Secondary Structure
MNQDEQKRAAAHAAIQHIPAGCIVGVGTGSTANYFIDALAGIRSRIDGAVASSEATARRL
CCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHH
SAHGIEVMDLNNVDELPLYVDGADEITPHLHMIKGGGGALTREKIVAAVAKKFICIADQS
HHCCEEEEECCCCCCCCEEECCCHHCCCCEEEEECCCCCHHHHHHHHHHHHHHEEECCCH
KLVDVLGKFPLPVEVIPMARGHVAREIVRLGGQPMLRQGFTTDNGNVILDVHALQILNPI
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEEHHHHHCCCH
ELETELNQITGIVTNGLFARRPADLLLLGDEGGIRTIAI
HHHHHHHHHHHHHHCCEECCCCCCEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA