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The map label for this gene is ptmB [H]

Identifier: 82701544

GI number: 82701544

Start: 454822

End: 455538

Strand: Direct

Name: ptmB [H]

Synonym: Nmul_A0410

Alternate gene names: 82701544

Gene position: 454822-455538 (Clockwise)

Preceding gene: 82701540

Following gene: 82701545

Centisome position: 14.28

GC content: 53.97

Gene sequence:

>717_bases
ATGTTGATTTATTCGCTCATTCCCGCGAGGGGAGGATCAAAAGCCGTACCCCATAAAAATATCCGGCCTTTGCGGGGAAA
ACCCCTGATCGCCCATTCGATTGAAGTCTCCCTCAAGTGTCCTTCCATTCGAAGGACTTTTGTCAGCACCGACTCGGAAG
CCATTGCCGGGCTCGCGAGAAACGCCGGCGCCGAGGTACCCTTTCTGAGGCCTGCTGAGTTCGCGCAGGACGATACCCGG
GATCTGCCGGTATTTCGGCATTTTCTCGAATGGCTGGAACAAAACCGGGTTCCGCTTCCCGACGCCATTTTCCAATTCCG
TCCGACTTCCCCCTTGCGCAGCGTTTCAAAAATAGAAGAAGCGGTTGAGCTCCTGGAAAAAAATCCCGAAGCCGATTCGG
TTCGCGGGGTCACGGAGCCGGGACAGAATCCCTACAAGATGTGGACTATCGGAGCGGATGGTTTCATGCGAGCCCTATTG
AACGTCCCGGGCATTCCCGAGCCCTTCAACGAGCCGAGGCAAAGCTTGCCCAAGGTCTACTGGCAAATCGGTTATTTGGA
TCTGATCCGTACCCGGACCATTCTGGAAAAAAATTCGCTCACGGGCACACACATCTTGCCGCTCAAGATCGACAGCAGGG
ACTCGATCGATATCGATGACGAATTCTCGTTTCAACTGGCCGAGTTTCTGATGGAAAGACAGGGAAGCGTCATTTGA

Upstream 100 bases:

>100_bases
TAGAAATAGAACGACTATTGACCTGCAAAATCGTCAATTCTGTCCTCACTCAGCCAATTTTTTGCTTCGATTCTTCAAGT
CCGACAGAGACTGCTGGCCG

Downstream 100 bases:

>100_bases
AGGCTCTGGTAGTTGGCCTTGGGTCCATTGGCGTGAGGCATCTCAACAACCTGCATGCACTCGAGGTTCGCGAACTCGGC
GTGGTGCGAAGCCGGAATTT

Product: acylneuraminate cytidylyltransferase

Products: diphosphate; CMP-N-acylneuraminate

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MLIYSLIPARGGSKAVPHKNIRPLRGKPLIAHSIEVSLKCPSIRRTFVSTDSEAIAGLARNAGAEVPFLRPAEFAQDDTR
DLPVFRHFLEWLEQNRVPLPDAIFQFRPTSPLRSVSKIEEAVELLEKNPEADSVRGVTEPGQNPYKMWTIGADGFMRALL
NVPGIPEPFNEPRQSLPKVYWQIGYLDLIRTRTILEKNSLTGTHILPLKIDSRDSIDIDDEFSFQLAEFLMERQGSVI

Sequences:

>Translated_238_residues
MLIYSLIPARGGSKAVPHKNIRPLRGKPLIAHSIEVSLKCPSIRRTFVSTDSEAIAGLARNAGAEVPFLRPAEFAQDDTR
DLPVFRHFLEWLEQNRVPLPDAIFQFRPTSPLRSVSKIEEAVELLEKNPEADSVRGVTEPGQNPYKMWTIGADGFMRALL
NVPGIPEPFNEPRQSLPKVYWQIGYLDLIRTRTILEKNSLTGTHILPLKIDSRDSIDIDDEFSFQLAEFLMERQGSVI
>Mature_238_residues
MLIYSLIPARGGSKAVPHKNIRPLRGKPLIAHSIEVSLKCPSIRRTFVSTDSEAIAGLARNAGAEVPFLRPAEFAQDDTR
DLPVFRHFLEWLEQNRVPLPDAIFQFRPTSPLRSVSKIEEAVELLEKNPEADSVRGVTEPGQNPYKMWTIGADGFMRALL
NVPGIPEPFNEPRQSLPKVYWQIGYLDLIRTRTILEKNSLTGTHILPLKIDSRDSIDIDDEFSFQLAEFLMERQGSVI

Specific function: Required for biosynthesis of LAH modification in the post-translational modification of Campylobacter coli flagellin [H]

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=239, Percent_Identity=27.6150627615063, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: 2.7.7.43

Molecular weight: Translated: 26857; Mature: 26857

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIYSLIPARGGSKAVPHKNIRPLRGKPLIAHSIEVSLKCPSIRRTFVSTDSEAIAGLAR
CEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHCCCHHHHHHHHH
NAGAEVPFLRPAEFAQDDTRDLPVFRHFLEWLEQNRVPLPDAIFQFRPTSPLRSVSKIEE
HCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHH
AVELLEKNPEADSVRGVTEPGQNPYKMWTIGADGFMRALLNVPGIPEPFNEPRQSLPKVY
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
WQIGYLDLIRTRTILEKNSLTGTHILPLKIDSRDSIDIDDEFSFQLAEFLMERQGSVI
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLIYSLIPARGGSKAVPHKNIRPLRGKPLIAHSIEVSLKCPSIRRTFVSTDSEAIAGLAR
CEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHCCCHHHHHHHHH
NAGAEVPFLRPAEFAQDDTRDLPVFRHFLEWLEQNRVPLPDAIFQFRPTSPLRSVSKIEE
HCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHH
AVELLEKNPEADSVRGVTEPGQNPYKMWTIGADGFMRALLNVPGIPEPFNEPRQSLPKVY
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
WQIGYLDLIRTRTILEKNSLTGTHILPLKIDSRDSIDIDDEFSFQLAEFLMERQGSVI
HHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CTP; N-acylneuraminate

Specific reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8825781 [H]