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The map label for this gene is fabF [H]

Identifier: 82701532

GI number: 82701532

Start: 440891

End: 442111

Strand: Reverse

Name: fabF [H]

Synonym: Nmul_A0398

Alternate gene names: 82701532

Gene position: 442111-440891 (Counterclockwise)

Preceding gene: 82701533

Following gene: 82701531

Centisome position: 13.88

GC content: 55.69

Gene sequence:

>1221_bases
ATGCGTGTAGTCGTTACAGGAATGGGAGTTGTTTCCCCCATTGGTATCGGGGTTGACCAGTTCTGGTCAGCCGCTGTCAA
GGGTGTGAGCGGAATAAAAAGGATAACCAGCTTTGATGCATCGAGCAGGCGTTCCCAAATTGCAGGAGAAGTGACGGACT
TTGATCCTTCAACCTTCCTCTCTCAAAAGTATATCGAGCAAACCGACAGGTTCACCCAGCTTGCCCTGCTTGCTGCGCGT
CTTGCCCTCGAGGACGCCGGCGGCCTTGAGGCTTATGAATCTCGCCGCATCGGGGTGAGCATAGGTTCGGGAATGGGTGG
TTTTTCCACCTTTGAATCGTCCGCGCTGCGCAAGTTTCGGAGTCAGCCGGTCCCGCCTTTCACCGTACCACGCACAATGG
CCAACTCCGCTGCGGCCTGGATCGCGATCAGGCATGGGTTCAAAGGCATGAACCTGACCTCCAGTACAGCTTGCTCTTCG
GGAGCCAATGCCATCGGTGCGGCACTCGATCTCCTGCGTGCAGGAAGAGCGGACGTTGTGGTCGCCGGCGGTGCTGAAGC
ATGCGTATTGCCGCTCACCATCAACGGTTTTGAGATATTGCACGCCCTGACCACCACTTCCAACGATAATCCAGCCAGAG
CCTCGCGTCCTTTCGCAAAAGGCCGCGATGGTTTTGTCATGGGAGAGGGTGCGGGAATACTGATCCTCGAGAAGGAAGAG
CAGGCCCGCCAGCGGGGAGCAAAAATATATGCCGAGCTTGCCGGCTATGGACAGGCATGTGATGCAACGCATATTGTCAT
GCCCGACATGGAAGGCCAGATCGCTGCCATGCAGGAAGCCATCCGTGATGCGGGAATGGAGCTGGATTCCATTGAGCATA
TCAATGCGCATGCGACTTCCACACCGCTGGGGGATACAGTCGAAACGCGGGCAATAAAAAATCTTTTTGGAGCGCGTGCT
GCTGACATTGCCATCAGCGCCACCAAATCGATGGTAGGGCATTCCATCGGCGCATCGGCAGCAATCGGCAGTATCGCCAC
CATCATGGCGCTTCATACCGGCACCATTCATCCGACCATCAATCTTGATGAGGCCGATCCCGAGTGTGACCTCGACTACA
CCCCCAACGTTGCGCAGAAAAGAAGTGTCCGCACCGGCTTGTGTAACGCTTTCGGATTTGGTGGCAACAATGCGAGCATT
CTTTTCACAACCCTTGCATGA

Upstream 100 bases:

>100_bases
TTAGGCTGCCCATTACATAACGAGCGCTCACCTGTTCGCTGCATTGAATACCTCCCCATAATGAGGTCGAGCAGATTCCC
ATGATTATTTCCGGTTTTGT

Downstream 100 bases:

>100_bases
AGGAAGAACTAGATATGGACACAGCGGAGATTGAAGCAAAGGTCATACAATTCATTGCCACAAAAGTCGAGAATCTCGAT
GCTTCCACTATCAACCGCTC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MRVVVTGMGVVSPIGIGVDQFWSAAVKGVSGIKRITSFDASSRRSQIAGEVTDFDPSTFLSQKYIEQTDRFTQLALLAAR
LALEDAGGLEAYESRRIGVSIGSGMGGFSTFESSALRKFRSQPVPPFTVPRTMANSAAAWIAIRHGFKGMNLTSSTACSS
GANAIGAALDLLRAGRADVVVAGGAEACVLPLTINGFEILHALTTTSNDNPARASRPFAKGRDGFVMGEGAGILILEKEE
QARQRGAKIYAELAGYGQACDATHIVMPDMEGQIAAMQEAIRDAGMELDSIEHINAHATSTPLGDTVETRAIKNLFGARA
ADIAISATKSMVGHSIGASAAIGSIATIMALHTGTIHPTINLDEADPECDLDYTPNVAQKRSVRTGLCNAFGFGGNNASI
LFTTLA

Sequences:

>Translated_406_residues
MRVVVTGMGVVSPIGIGVDQFWSAAVKGVSGIKRITSFDASSRRSQIAGEVTDFDPSTFLSQKYIEQTDRFTQLALLAAR
LALEDAGGLEAYESRRIGVSIGSGMGGFSTFESSALRKFRSQPVPPFTVPRTMANSAAAWIAIRHGFKGMNLTSSTACSS
GANAIGAALDLLRAGRADVVVAGGAEACVLPLTINGFEILHALTTTSNDNPARASRPFAKGRDGFVMGEGAGILILEKEE
QARQRGAKIYAELAGYGQACDATHIVMPDMEGQIAAMQEAIRDAGMELDSIEHINAHATSTPLGDTVETRAIKNLFGARA
ADIAISATKSMVGHSIGASAAIGSIATIMALHTGTIHPTINLDEADPECDLDYTPNVAQKRSVRTGLCNAFGFGGNNASI
LFTTLA
>Mature_406_residues
MRVVVTGMGVVSPIGIGVDQFWSAAVKGVSGIKRITSFDASSRRSQIAGEVTDFDPSTFLSQKYIEQTDRFTQLALLAAR
LALEDAGGLEAYESRRIGVSIGSGMGGFSTFESSALRKFRSQPVPPFTVPRTMANSAAAWIAIRHGFKGMNLTSSTACSS
GANAIGAALDLLRAGRADVVVAGGAEACVLPLTINGFEILHALTTTSNDNPARASRPFAKGRDGFVMGEGAGILILEKEE
QARQRGAKIYAELAGYGQACDATHIVMPDMEGQIAAMQEAIRDAGMELDSIEHINAHATSTPLGDTVETRAIKNLFGARA
ADIAISATKSMVGHSIGASAAIGSIATIMALHTGTIHPTINLDEADPECDLDYTPNVAQKRSVRTGLCNAFGFGGNNASI
LFTTLA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=420, Percent_Identity=41.9047619047619, Blast_Score=311, Evalue=5e-85,
Organism=Homo sapiens, GI223972627, Length=150, Percent_Identity=45.3333333333333, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI41872631, Length=419, Percent_Identity=26.7303102625298, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1787337, Length=411, Percent_Identity=45.4987834549878, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1788663, Length=409, Percent_Identity=35.6968215158924, Blast_Score=235, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI71983541, Length=416, Percent_Identity=34.375, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71983535, Length=261, Percent_Identity=37.9310344827586, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17550940, Length=343, Percent_Identity=24.198250728863, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=369, Percent_Identity=24.9322493224932, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=441, Percent_Identity=33.5600907029478, Blast_Score=223, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6325025, Length=236, Percent_Identity=25.8474576271186, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24644341, Length=423, Percent_Identity=40.4255319148936, Blast_Score=284, Evalue=8e-77,
Organism=Drosophila melanogaster, GI24581345, Length=275, Percent_Identity=25.8181818181818, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19920632, Length=367, Percent_Identity=25.3405994550409, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221330659, Length=367, Percent_Identity=25.3405994550409, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42485; Mature: 42485

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVVTGMGVVSPIGIGVDQFWSAAVKGVSGIKRITSFDASSRRSQIAGEVTDFDPSTFL
CEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHH
SQKYIEQTDRFTQLALLAARLALEDAGGLEAYESRRIGVSIGSGMGGFSTFESSALRKFR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCHHHHHHHHHHHHH
SQPVPPFTVPRTMANSAAAWIAIRHGFKGMNLTSSTACSSGANAIGAALDLLRAGRADVV
CCCCCCCCCCHHHHCCHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
VAGGAEACVLPLTINGFEILHALTTTSNDNPARASRPFAKGRDGFVMGEGAGILILEKEE
EECCCCEEEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECHH
QARQRGAKIYAELAGYGQACDATHIVMPDMEGQIAAMQEAIRDAGMELDSIEHINAHATS
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCC
TPLGDTVETRAIKNLFGARAADIAISATKSMVGHSIGASAAIGSIATIMALHTGTIHPTI
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEE
NLDEADPECDLDYTPNVAQKRSVRTGLCNAFGFGGNNASILFTTLA
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MRVVVTGMGVVSPIGIGVDQFWSAAVKGVSGIKRITSFDASSRRSQIAGEVTDFDPSTFL
CEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHH
SQKYIEQTDRFTQLALLAARLALEDAGGLEAYESRRIGVSIGSGMGGFSTFESSALRKFR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCHHHHHHHHHHHHH
SQPVPPFTVPRTMANSAAAWIAIRHGFKGMNLTSSTACSSGANAIGAALDLLRAGRADVV
CCCCCCCCCCHHHHCCHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
VAGGAEACVLPLTINGFEILHALTTTSNDNPARASRPFAKGRDGFVMGEGAGILILEKEE
EECCCCEEEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEECHH
QARQRGAKIYAELAGYGQACDATHIVMPDMEGQIAAMQEAIRDAGMELDSIEHINAHATS
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHCCCCCCC
TPLGDTVETRAIKNLFGARAADIAISATKSMVGHSIGASAAIGSIATIMALHTGTIHPTI
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEE
NLDEADPECDLDYTPNVAQKRSVRTGLCNAFGFGGNNASILFTTLA
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]