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The map label for this gene is ntrY [H]

Identifier: 82701524

GI number: 82701524

Start: 430486

End: 432720

Strand: Reverse

Name: ntrY [H]

Synonym: Nmul_A0390

Alternate gene names: 82701524

Gene position: 432720-430486 (Counterclockwise)

Preceding gene: 82701525

Following gene: 82701523

Centisome position: 13.59

GC content: 56.78

Gene sequence:

>2235_bases
ATGATGAAATACCTCATCATCGCCGGCGTGGCGCTGGGGGCGATCATGCTGCTCCTGCTCGCGAGCGCTGGCGCCGATAC
CGGACTCTTCGACCGCAAATACAGACTGCTGATCAGGCTCAACGCCGGTTTGGTGCTGTTCCTCATGGCAATCGTCGGAT
ACCTGCTATGGAGGCTCAGGCGCAGGCTTCAGGCGGGCGTATTCGGTTCCAGACTGGCGCTGCGCCTGTTGCTGATCTTC
TCGCTGATGGCGGTGCTCCCGGGCGTCCTGGTCTATAGCATATCGGTCCAGTTTCTGGGAAAAAGCATCGAATCGTGGTT
CGACGTAAAAGTGGACCGCGCTCTGGAAGGCGGGCTGGAACTGGGGCGCACCATTCTCGACAGCCGGCTGGAAGATCTGC
ACAGGGAAGCCGATCTCGCCGCACTTGCATTATCCGAGCAGGCGGGACCATTGCCACCGGTATTAAACCAACTCGTCCAT
CAAATGCAGGCGCAGGAAGCAGTCCTGTTCGATCACGAAGGTAACGTCGTTGCATTTGCACGTGCGGACACGAGTGAAAC
CGTCCCTGACGCACTTAGTACAACTTCACTGCATCAGATCAGGACGGAGAACGGATACAGCACGATCGAGTCGATTGCCG
GCGAAGGTTTGTACCTGAAGGTATGGTCGCCTATCGATGTTCCCGGCGTAAGAAACAATACGCGGATTCTGCAGTTGACG
CAGCCCGTGCCGACACAACTGGCGGAAGACGCGGAAATAGTACAGGCAGCCTATCGGGACTACCAGGAATTGCTGCTGTC
ACGCGAAGGTCTCAAACACCTCTACGGGGTGACCCTGACGCTCGCGCTGCTGCTTGCGCTTTTCTCTGCCCTGGCCGCTG
CATTCCTGATCAGCGAACGGCTCAGCGCACCTCTGGGAATGCTGGCGGAGGGCACGCGAGCGGTTGCGCAGGGCGACTTC
AGCAGGCGCCATCCGGTACGGAGCCGCGACGAACTGGGCGTACTGACCGAATCATTCAATCTCATGACCCAACAGTTGGA
GGAAGCGCGGATAACTGCCCAGCACAATCAACAGGAAGTGGAAAGCGCGCGGGCTTATCTGGAAAACATCCTGGCCAATC
TTTCCTCGGGCGTCCTGGTATTCGATGAAAGCCTGCACTTGCGCACAGCCAATCTAAGCGCGGAGCAAATCCTGAACGTC
CCGCTGCCCGGTCTGGAAGGGCTGACGATCGAGGAATGCGCGATGCGTGAATCCGAGTTGCATGCCTTCGCATATGGAAT
TCTGGAAGGATTTCATTCGGAAACAAAGGGCGAGTGGCAGCGCCAGGTAGAGCGAACGAGGGAGGGCACGCGTCAGGTCC
TGCTGCTACGGGGAACATGGCTGGCGCATGTGCCGGGCGGGGGAGGCGTCGTCGTGTTCGACGATATCACCCATCTGCTG
GAGACTCAGCGCGCTGCAGCCTGGGGAGAAGTGGCGCGCCGTCTGGCGCATGAAATAAAGAATCCTCTGACGCCGATACA
ACTGTCCGCTGAACGCATACAACACAAGCTTGCCGCGAAGCTGAATGACAATGACGCGCAAATTCTGCATCGTTCCACCG
AAACGATCGTCAATCAGGTGGAAGCGCTCAAAAGAATGGTCAATGAATTCAGCGAATACGCGCGTGCGCCTGAACCCGAA
TTTCACCTGCTGGATTTCAATGCACTGGTACGGGAAGTACTGGCCTTATATGAAAGTCCAGCCACAGCAGCGCCGGATAA
TCGGCAACCACACATCGATCTGGTTCTGGTGCCCGACCTGCCGATGATGAAAGGTGACTCCGCGCGACTGCGCCAGGTGA
TCCACAATCTCCTGCAGAATGCGCAGGATGCGCTGGCGGGTTTGCCTCAGCCCGCAATCATGATAAAAACGGAAACGCTG
CCCTCAGGCATACGTTTCACCGTCAGCGATAACGGCGGGGGGTTTCCTGAACAGGTGAGAGCACGGGTATTTGAACCCTA
TGTGACAACAAAACCGAAAGGGACCGGACTGGGTCTTCCCATTGTAAAAAAGATAATCGAAGAACACAGGGGAACGATAC
AGATTGAAAATAGGCGACCGCACGGCGCGCGTATTTCAATCGTACTCCCCCTCTCCCCGGACAAACTCGTGGTTTCTCTC
AAAGATGGATGGTTCCGACCGATCGCGGGAGAGCCAGCGCTTTCACTTTCCTGTGAACTGCAGTCAAAAGAATAA

Upstream 100 bases:

>100_bases
TCCAGGTGGAAACGCTCGGCTCCCGGGAATGGGATCTCGGTTCCGGTACTTTGCGGTGGAATACCCGCTTACCCTCCCAG
AAGCTGCAGGACAACAGCAA

Downstream 100 bases:

>100_bases
GAGGTAAGCTTGACGTTCAATTTCATTTCCGTGGCAAGCAAATCTATTCCTGGAATTATGAGCAACAATACGATACTGAT
CGTTGACGATGAAATCGGCA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 744; Mature: 744

Protein sequence:

>744_residues
MMKYLIIAGVALGAIMLLLLASAGADTGLFDRKYRLLIRLNAGLVLFLMAIVGYLLWRLRRRLQAGVFGSRLALRLLLIF
SLMAVLPGVLVYSISVQFLGKSIESWFDVKVDRALEGGLELGRTILDSRLEDLHREADLAALALSEQAGPLPPVLNQLVH
QMQAQEAVLFDHEGNVVAFARADTSETVPDALSTTSLHQIRTENGYSTIESIAGEGLYLKVWSPIDVPGVRNNTRILQLT
QPVPTQLAEDAEIVQAAYRDYQELLLSREGLKHLYGVTLTLALLLALFSALAAAFLISERLSAPLGMLAEGTRAVAQGDF
SRRHPVRSRDELGVLTESFNLMTQQLEEARITAQHNQQEVESARAYLENILANLSSGVLVFDESLHLRTANLSAEQILNV
PLPGLEGLTIEECAMRESELHAFAYGILEGFHSETKGEWQRQVERTREGTRQVLLLRGTWLAHVPGGGGVVVFDDITHLL
ETQRAAAWGEVARRLAHEIKNPLTPIQLSAERIQHKLAAKLNDNDAQILHRSTETIVNQVEALKRMVNEFSEYARAPEPE
FHLLDFNALVREVLALYESPATAAPDNRQPHIDLVLVPDLPMMKGDSARLRQVIHNLLQNAQDALAGLPQPAIMIKTETL
PSGIRFTVSDNGGGFPEQVRARVFEPYVTTKPKGTGLGLPIVKKIIEEHRGTIQIENRRPHGARISIVLPLSPDKLVVSL
KDGWFRPIAGEPALSLSCELQSKE

Sequences:

>Translated_744_residues
MMKYLIIAGVALGAIMLLLLASAGADTGLFDRKYRLLIRLNAGLVLFLMAIVGYLLWRLRRRLQAGVFGSRLALRLLLIF
SLMAVLPGVLVYSISVQFLGKSIESWFDVKVDRALEGGLELGRTILDSRLEDLHREADLAALALSEQAGPLPPVLNQLVH
QMQAQEAVLFDHEGNVVAFARADTSETVPDALSTTSLHQIRTENGYSTIESIAGEGLYLKVWSPIDVPGVRNNTRILQLT
QPVPTQLAEDAEIVQAAYRDYQELLLSREGLKHLYGVTLTLALLLALFSALAAAFLISERLSAPLGMLAEGTRAVAQGDF
SRRHPVRSRDELGVLTESFNLMTQQLEEARITAQHNQQEVESARAYLENILANLSSGVLVFDESLHLRTANLSAEQILNV
PLPGLEGLTIEECAMRESELHAFAYGILEGFHSETKGEWQRQVERTREGTRQVLLLRGTWLAHVPGGGGVVVFDDITHLL
ETQRAAAWGEVARRLAHEIKNPLTPIQLSAERIQHKLAAKLNDNDAQILHRSTETIVNQVEALKRMVNEFSEYARAPEPE
FHLLDFNALVREVLALYESPATAAPDNRQPHIDLVLVPDLPMMKGDSARLRQVIHNLLQNAQDALAGLPQPAIMIKTETL
PSGIRFTVSDNGGGFPEQVRARVFEPYVTTKPKGTGLGLPIVKKIIEEHRGTIQIENRRPHGARISIVLPLSPDKLVVSL
KDGWFRPIAGEPALSLSCELQSKE
>Mature_744_residues
MMKYLIIAGVALGAIMLLLLASAGADTGLFDRKYRLLIRLNAGLVLFLMAIVGYLLWRLRRRLQAGVFGSRLALRLLLIF
SLMAVLPGVLVYSISVQFLGKSIESWFDVKVDRALEGGLELGRTILDSRLEDLHREADLAALALSEQAGPLPPVLNQLVH
QMQAQEAVLFDHEGNVVAFARADTSETVPDALSTTSLHQIRTENGYSTIESIAGEGLYLKVWSPIDVPGVRNNTRILQLT
QPVPTQLAEDAEIVQAAYRDYQELLLSREGLKHLYGVTLTLALLLALFSALAAAFLISERLSAPLGMLAEGTRAVAQGDF
SRRHPVRSRDELGVLTESFNLMTQQLEEARITAQHNQQEVESARAYLENILANLSSGVLVFDESLHLRTANLSAEQILNV
PLPGLEGLTIEECAMRESELHAFAYGILEGFHSETKGEWQRQVERTREGTRQVLLLRGTWLAHVPGGGGVVVFDDITHLL
ETQRAAAWGEVARRLAHEIKNPLTPIQLSAERIQHKLAAKLNDNDAQILHRSTETIVNQVEALKRMVNEFSEYARAPEPE
FHLLDFNALVREVLALYESPATAAPDNRQPHIDLVLVPDLPMMKGDSARLRQVIHNLLQNAQDALAGLPQPAIMIKTETL
PSGIRFTVSDNGGGFPEQVRARVFEPYVTTKPKGTGLGLPIVKKIIEEHRGTIQIENRRPHGARISIVLPLSPDKLVVSL
KDGWFRPIAGEPALSLSCELQSKE

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=428, Percent_Identity=25.9345794392523, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1790436, Length=230, Percent_Identity=29.5652173913043, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1789808, Length=234, Percent_Identity=25.2136752136752, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=363, Percent_Identity=25.8953168044077, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=26.4822134387352, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=24.5535714285714, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=29.0178571428571, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82183; Mature: 82183

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKYLIIAGVALGAIMLLLLASAGADTGLFDRKYRLLIRLNAGLVLFLMAIVGYLLWRLR
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHH
RRLQAGVFGSRLALRLLLIFSLMAVLPGVLVYSISVQFLGKSIESWFDVKVDRALEGGLE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGRTILDSRLEDLHREADLAALALSEQAGPLPPVLNQLVHQMQAQEAVLFDHEGNVVAFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEE
RADTSETVPDALSTTSLHQIRTENGYSTIESIAGEGLYLKVWSPIDVPGVRNNTRILQLT
ECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEC
QPVPTQLAEDAEIVQAAYRDYQELLLSREGLKHLYGVTLTLALLLALFSALAAAFLISER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAPLGMLAEGTRAVAQGDFSRRHPVRSRDELGVLTESFNLMTQQLEEARITAQHNQQEV
HCCCHHHHHHCCHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ESARAYLENILANLSSGVLVFDESLHLRTANLSAEQILNVPLPGLEGLTIEECAMRESEL
HHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
HAFAYGILEGFHSETKGEWQRQVERTREGTRQVLLLRGTWLAHVPGGGGVVVFDDITHLL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCCEEEHHHHHHHH
ETQRAAAWGEVARRLAHEIKNPLTPIQLSAERIQHKLAAKLNDNDAQILHRSTETIVNQV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EALKRMVNEFSEYARAPEPEFHLLDFNALVREVLALYESPATAAPDNRQPHIDLVLVPDL
HHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC
PMMKGDSARLRQVIHNLLQNAQDALAGLPQPAIMIKTETLPSGIRFTVSDNGGGFPEQVR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCCHHHHH
ARVFEPYVTTKPKGTGLGLPIVKKIIEEHRGTIQIENRRPHGARISIVLPLSPDKLVVSL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCEEEEE
KDGWFRPIAGEPALSLSCELQSKE
CCCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MMKYLIIAGVALGAIMLLLLASAGADTGLFDRKYRLLIRLNAGLVLFLMAIVGYLLWRLR
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHH
RRLQAGVFGSRLALRLLLIFSLMAVLPGVLVYSISVQFLGKSIESWFDVKVDRALEGGLE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGRTILDSRLEDLHREADLAALALSEQAGPLPPVLNQLVHQMQAQEAVLFDHEGNVVAFA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEEE
RADTSETVPDALSTTSLHQIRTENGYSTIESIAGEGLYLKVWSPIDVPGVRNNTRILQLT
ECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEC
QPVPTQLAEDAEIVQAAYRDYQELLLSREGLKHLYGVTLTLALLLALFSALAAAFLISER
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAPLGMLAEGTRAVAQGDFSRRHPVRSRDELGVLTESFNLMTQQLEEARITAQHNQQEV
HCCCHHHHHHCCHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ESARAYLENILANLSSGVLVFDESLHLRTANLSAEQILNVPLPGLEGLTIEECAMRESEL
HHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
HAFAYGILEGFHSETKGEWQRQVERTREGTRQVLLLRGTWLAHVPGGGGVVVFDDITHLL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCEEEECCCCCCEEEHHHHHHHH
ETQRAAAWGEVARRLAHEIKNPLTPIQLSAERIQHKLAAKLNDNDAQILHRSTETIVNQV
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EALKRMVNEFSEYARAPEPEFHLLDFNALVREVLALYESPATAAPDNRQPHIDLVLVPDL
HHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC
PMMKGDSARLRQVIHNLLQNAQDALAGLPQPAIMIKTETLPSGIRFTVSDNGGGFPEQVR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCCCCHHHHH
ARVFEPYVTTKPKGTGLGLPIVKKIIEEHRGTIQIENRRPHGARISIVLPLSPDKLVVSL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCEEEEE
KDGWFRPIAGEPALSLSCELQSKE
CCCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]