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The map label for this gene is macB [H]

Identifier: 82701504

GI number: 82701504

Start: 402055

End: 403284

Strand: Reverse

Name: macB [H]

Synonym: Nmul_A0370

Alternate gene names: 82701504

Gene position: 403284-402055 (Counterclockwise)

Preceding gene: 82701507

Following gene: 82701503

Centisome position: 12.66

GC content: 52.68

Gene sequence:

>1230_bases
GTGGATCGTATTCGGCTCGACTTTTTGCTTGCATTTCGAAATATGGTGCGGCACAAGCGTCGCAGCGCCATCGCTGTGGG
CGCGGTTACGTTTGGCATTATCGCCCTGATCCTTGCAGCGGGCTTTATCGAGTGGATATTCTGGGGCATGCAGGAAGCCA
CCATCCAGTCGCAACTCGGCCATATCCAGATCAGCAGACCGGGCTATCAGGAAGCAGGAAAAGCTGATCCATACGCTTAT
CTTTTACCGGATGCAATTCCTGAACTGGAACCGGCAAACGGTCCAGCTCAAATCAAGACCATCATCCCCCGCCTCTCCTT
TGGCGGTCTGATCAGTCACGGAGACGCAACTCTTTCATTTGTTGGAGAAGGAGTCATCCCAGAGGAAAAGGCCATTCTCA
GCGGCTCGGTGGAAATTTCTGCGGGTGAAAATCTTTCAGTAGATGCCCCGAAGGGCATTATTCTAGGTGTGGGTCTTGGC
CGCAACCTCAACGTAAACATTGGCGATAAGGTTGTGCTATTGGCGAGTACCGCATCAAGGGGCGTCAATGCGGTTGAGGT
CACTGTCCGGGGATTGTTCTCCACTGTAAACAAGTCTTACGACGATATCGCCCTACGCATGCCGATCGAAACAGCCCGCC
AACTCCTCCGGGTCAAAGGTTCTCACGTATGGGTAGTGTTGTTGAATGACACAGCGAAGACCGATACTGTACTCCAAAGA
TTACGCGATTCATTGCAAAAGAGCGATTTCGAGGTGGTTCCCTGGTATGTCCTGGCTGATTTCTACAATAAGACCGTGGC
TTTGTTTACAAAACAAATCCATGGCCTCAAGCTGATAATCGCCTTCATCATCCTTCTTGCCATTTTGAATGCCATGACGA
TGTCGGTAATGGAGCGGATCGGGGAAATTGGTACTGATATGGCGCTTGGCGCCAGACGCATCGACGTTCTCCGACGCTTC
CTAAGCGAAGGCATTCTGCTCGGCGGTTTCGGCGGCCTGCTCGGGGTTACGATAGGGGTAGCGCTGGCTGCCATGATATC
GAGCATAGGGATCCCGATGCCGCCCCCCCCAGGGACGACCCGTGGCTATACGGGCGAAATACTTGTCACGTGGAATATTG
CATTCGAATCCCTTTTGCTTGCGATCGGCGCAACGCTCACTGCCAGTATATACCCAGCCTGGAAGGCATCCCGCATGCAG
ATAGTGGATGCGCTACGTCACAATAGATAA

Upstream 100 bases:

>100_bases
AGGCGCAAGCAGAGAACTCGTTTCCCTGTTAACTCGTTCCCCTGTTCTCCCGGGCGATAGCGCGATGTGGCAGCGCGCAC
TGAGCAGAAGGATATAGAGG

Downstream 100 bases:

>100_bases
TTCGGAAAAGTGAATAATGCTCAGACTGGCCTTTCGAAATATTTTTCGACAGAAATCACACACCGCAATGACTCTGGCGG
CGATCGTGAGCGGCGTGGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MDRIRLDFLLAFRNMVRHKRRSAIAVGAVTFGIIALILAAGFIEWIFWGMQEATIQSQLGHIQISRPGYQEAGKADPYAY
LLPDAIPELEPANGPAQIKTIIPRLSFGGLISHGDATLSFVGEGVIPEEKAILSGSVEISAGENLSVDAPKGIILGVGLG
RNLNVNIGDKVVLLASTASRGVNAVEVTVRGLFSTVNKSYDDIALRMPIETARQLLRVKGSHVWVVLLNDTAKTDTVLQR
LRDSLQKSDFEVVPWYVLADFYNKTVALFTKQIHGLKLIIAFIILLAILNAMTMSVMERIGEIGTDMALGARRIDVLRRF
LSEGILLGGFGGLLGVTIGVALAAMISSIGIPMPPPPGTTRGYTGEILVTWNIAFESLLLAIGATLTASIYPAWKASRMQ
IVDALRHNR

Sequences:

>Translated_409_residues
MDRIRLDFLLAFRNMVRHKRRSAIAVGAVTFGIIALILAAGFIEWIFWGMQEATIQSQLGHIQISRPGYQEAGKADPYAY
LLPDAIPELEPANGPAQIKTIIPRLSFGGLISHGDATLSFVGEGVIPEEKAILSGSVEISAGENLSVDAPKGIILGVGLG
RNLNVNIGDKVVLLASTASRGVNAVEVTVRGLFSTVNKSYDDIALRMPIETARQLLRVKGSHVWVVLLNDTAKTDTVLQR
LRDSLQKSDFEVVPWYVLADFYNKTVALFTKQIHGLKLIIAFIILLAILNAMTMSVMERIGEIGTDMALGARRIDVLRRF
LSEGILLGGFGGLLGVTIGVALAAMISSIGIPMPPPPGTTRGYTGEILVTWNIAFESLLLAIGATLTASIYPAWKASRMQ
IVDALRHNR
>Mature_409_residues
MDRIRLDFLLAFRNMVRHKRRSAIAVGAVTFGIIALILAAGFIEWIFWGMQEATIQSQLGHIQISRPGYQEAGKADPYAY
LLPDAIPELEPANGPAQIKTIIPRLSFGGLISHGDATLSFVGEGVIPEEKAILSGSVEISAGENLSVDAPKGIILGVGLG
RNLNVNIGDKVVLLASTASRGVNAVEVTVRGLFSTVNKSYDDIALRMPIETARQLLRVKGSHVWVVLLNDTAKTDTVLQR
LRDSLQKSDFEVVPWYVLADFYNKTVALFTKQIHGLKLIIAFIILLAILNAMTMSVMERIGEIGTDMALGARRIDVLRRF
LSEGILLGGFGGLLGVTIGVALAAMISSIGIPMPPPPGTTRGYTGEILVTWNIAFESLLLAIGATLTASIYPAWKASRMQ
IVDALRHNR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=186, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44263; Mature: 44263

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRLDFLLAFRNMVRHKRRSAIAVGAVTFGIIALILAAGFIEWIFWGMQEATIQSQLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HIQISRPGYQEAGKADPYAYLLPDAIPELEPANGPAQIKTIIPRLSFGGLISHGDATLSF
EEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEE
VGEGVIPEEKAILSGSVEISAGENLSVDAPKGIILGVGLGRNLNVNIGDKVVLLASTASR
CCCCCCCCCHHHEECCEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEEEECCCC
GVNAVEVTVRGLFSTVNKSYDDIALRMPIETARQLLRVKGSHVWVVLLNDTAKTDTVLQR
CCCEEHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
LRDSLQKSDFEVVPWYVLADFYNKTVALFTKQIHGLKLIIAFIILLAILNAMTMSVMERI
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEIGTDMALGARRIDVLRRFLSEGILLGGFGGLLGVTIGVALAAMISSIGIPMPPPPGTT
HHHCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RGYTGEILVTWNIAFESLLLAIGATLTASIYPAWKASRMQIVDALRHNR
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDRIRLDFLLAFRNMVRHKRRSAIAVGAVTFGIIALILAAGFIEWIFWGMQEATIQSQLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HIQISRPGYQEAGKADPYAYLLPDAIPELEPANGPAQIKTIIPRLSFGGLISHGDATLSF
EEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCEEEE
VGEGVIPEEKAILSGSVEISAGENLSVDAPKGIILGVGLGRNLNVNIGDKVVLLASTASR
CCCCCCCCCHHHEECCEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEEEECCCC
GVNAVEVTVRGLFSTVNKSYDDIALRMPIETARQLLRVKGSHVWVVLLNDTAKTDTVLQR
CCCEEHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHH
LRDSLQKSDFEVVPWYVLADFYNKTVALFTKQIHGLKLIIAFIILLAILNAMTMSVMERI
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEIGTDMALGARRIDVLRRFLSEGILLGGFGGLLGVTIGVALAAMISSIGIPMPPPPGTT
HHHCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
RGYTGEILVTWNIAFESLLLAIGATLTASIYPAWKASRMQIVDALRHNR
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA