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The map label for this gene is rrmA [C]

Identifier: 82701421

GI number: 82701421

Start: 307790

End: 308668

Strand: Direct

Name: rrmA [C]

Synonym: Nmul_A0287

Alternate gene names: 82701421

Gene position: 307790-308668 (Clockwise)

Preceding gene: 82701420

Following gene: 82701422

Centisome position: 9.67

GC content: 51.76

Gene sequence:

>879_bases
TTGAAAATCTGCTTGTCATGCAGCGCCAGATTTACCGATTCCGGGTGGCGATGTCCCGTTTGCTTCTCGACCCCCGAGCA
GGTGGATGGGTTTCTCAGTTTTGCGCCAGCACAGGCGAAATCTGATGAAGGATTTCAGCCGCATCACTTCAATGAGCTGG
CGCAAGCAGAAGCGGAGCACTTCTGGTTTCGTTCGCGCAATCGACTCATCATATGGGCGTTACATCGTTTTTTCCCGGAT
GCCAGGAAATTTCTTGAAATCGGTTGCGGAACAGGATTTGTGCTGTCGGGCATAGCACAGGACAATCCCCGTCTCGAAAT
CAGTGGAAGCGAGATTCATTCGGCGGGCTTGAGTCACGCGGCAGATCGCGCAAGGAACGCCACACTGTTTCAAATGGATG
CCCGCGATATTCCTTTTGATAGCGAATTCGATGTCATCGGTGCTTTTGATGTGCTTGAACACATTGAGGAAGACTCGCAG
GTATTGTTGCAAATGTTTCGCGCCATCTCACCCGGGGGAGGTATGATTGTCACCGTGCCCCAACACCGTTTCCTGTGGAG
TCAGCAGGATGAGCATGCGTGTCATGTTCGACGCTATGAAGCTCAGGAACTGCAGGATAAGGTGGAAAAGGCGGGATTTC
GGGTGGAAAAGGCGACATCGTTTGTATCGCTGCTGTTACCTCTGATGTTCATATCGCGATTGTCCAAACGCAAACCTGTC
GAGAACTATGACCCGACACAGGAGTTCAGGATCAAAAAATGGGTAAACACGATTCTCGAGGGAATCCTTGATCTGGAACG
TCTGATGATTCGCGGGCGAGTCTCATTTCCGATGGGCGGGTCGCGATTGCTGATTGCCCGAAAACCAGCAGGGGCGTAA

Upstream 100 bases:

>100_bases
TAATTGTTTTGAGCAATCTGCTGTTCCATGAAGCGATCACGATGCCGAAAATGCTCGGTCTGGGTTTGATTATCCTCGGC
ATCGCAGTCGGGAGCCGGGG

Downstream 100 bases:

>100_bases
TCACCATATGCAAATACCGTTCAACAAACCCTATATGACCGGGAAGGAGCTATGGTATGTCAGCCAGGCTCATGCGAACG
GACATCTGGCCGGCGACGGG

Product: generic methyltransferase

Products: S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

Alternate protein names: Methyltransferase; Generic Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase Domain Family Protein; S-Adenosyl-L-Methionine-Dependent Methyltransferase; 3-Demethylubiquinone-9 3-O-Methyltransferase

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKICLSCSARFTDSGWRCPVCFSTPEQVDGFLSFAPAQAKSDEGFQPHHFNELAQAEAEHFWFRSRNRLIIWALHRFFPD
ARKFLEIGCGTGFVLSGIAQDNPRLEISGSEIHSAGLSHAADRARNATLFQMDARDIPFDSEFDVIGAFDVLEHIEEDSQ
VLLQMFRAISPGGGMIVTVPQHRFLWSQQDEHACHVRRYEAQELQDKVEKAGFRVEKATSFVSLLLPLMFISRLSKRKPV
ENYDPTQEFRIKKWVNTILEGILDLERLMIRGRVSFPMGGSRLLIARKPAGA

Sequences:

>Translated_292_residues
MKICLSCSARFTDSGWRCPVCFSTPEQVDGFLSFAPAQAKSDEGFQPHHFNELAQAEAEHFWFRSRNRLIIWALHRFFPD
ARKFLEIGCGTGFVLSGIAQDNPRLEISGSEIHSAGLSHAADRARNATLFQMDARDIPFDSEFDVIGAFDVLEHIEEDSQ
VLLQMFRAISPGGGMIVTVPQHRFLWSQQDEHACHVRRYEAQELQDKVEKAGFRVEKATSFVSLLLPLMFISRLSKRKPV
ENYDPTQEFRIKKWVNTILEGILDLERLMIRGRVSFPMGGSRLLIARKPAGA
>Mature_292_residues
MKICLSCSARFTDSGWRCPVCFSTPEQVDGFLSFAPAQAKSDEGFQPHHFNELAQAEAEHFWFRSRNRLIIWALHRFFPD
ARKFLEIGCGTGFVLSGIAQDNPRLEISGSEIHSAGLSHAADRARNATLFQMDARDIPFDSEFDVIGAFDVLEHIEEDSQ
VLLQMFRAISPGGGMIVTVPQHRFLWSQQDEHACHVRRYEAQELQDKVEKAGFRVEKATSFVSLLLPLMFISRLSKRKPV
ENYDPTQEFRIKKWVNTILEGILDLERLMIRGRVSFPMGGSRLLIARKPAGA

Specific function: Specifically Methylates The Guanosine In Position 745 Of 23s rRNA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.51 [C]

Molecular weight: Translated: 33170; Mature: 33170

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKICLSCSARFTDSGWRCPVCFSTPEQVDGFLSFAPAQAKSDEGFQPHHFNELAQAEAEH
CEEEEECCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
FWFRSRNRLIIWALHRFFPDARKFLEIGCGTGFVLSGIAQDNPRLEISGSEIHSAGLSHA
HHHHCCCCEEEEEHHHHCHHHHHHHHHCCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHH
ADRARNATLFQMDARDIPFDSEFDVIGAFDVLEHIEEDSQVLLQMFRAISPGGGMIVTVP
HHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEC
QHRFLWSQQDEHACHVRRYEAQELQDKVEKAGFRVEKATSFVSLLLPLMFISRLSKRKPV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
ENYDPTQEFRIKKWVNTILEGILDLERLMIRGRVSFPMGGSRLLIARKPAGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MKICLSCSARFTDSGWRCPVCFSTPEQVDGFLSFAPAQAKSDEGFQPHHFNELAQAEAEH
CEEEEECCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
FWFRSRNRLIIWALHRFFPDARKFLEIGCGTGFVLSGIAQDNPRLEISGSEIHSAGLSHA
HHHHCCCCEEEEEHHHHCHHHHHHHHHCCCCCHHHHCCCCCCCEEEECCCHHHHHHHHHH
ADRARNATLFQMDARDIPFDSEFDVIGAFDVLEHIEEDSQVLLQMFRAISPGGGMIVTVP
HHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEC
QHRFLWSQQDEHACHVRRYEAQELQDKVEKAGFRVEKATSFVSLLLPLMFISRLSKRKPV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
ENYDPTQEFRIKKWVNTILEGILDLERLMIRGRVSFPMGGSRLLIARKPAGA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Unidentified protein factor B [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; rRNA [C]

Specific reaction: S-Adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine +rRNA containing Nmethylguanine [C]

General reaction: Methyl group transfer [C]

Inhibitor: Mg2+; Unidentified protein factor A1 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA