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The map label for this gene is ctaC [H]

Identifier: 82701317

GI number: 82701317

Start: 194765

End: 195898

Strand: Direct

Name: ctaC [H]

Synonym: Nmul_A0183

Alternate gene names: 82701317

Gene position: 194765-195898 (Clockwise)

Preceding gene: 82701315

Following gene: 82701318

Centisome position: 6.12

GC content: 59.52

Gene sequence:

>1134_bases
ATGAGCAGTAAAGCAGCAGCAGGTGTAGCGGGGATTGTGGCGGTCGCATGGAATTCAGGACTGGCGCTGGCGGCAGCCGA
CCCCTACCAGTTAAATCTGCCCGAGCCGCAGACTGTGATTGCCCAGCAGATCTACGACCAGCACACGCTGGTTCTGTGGA
TTTGCCTGGCGATATTCGTCGGCGTGTTCGGCGTGATGTTCTATTCGGTAATCCAGCATCGCAAATCCAAGGGCTATAAG
GCGGCCAATTTCCATCACAGCACCACGGTCGAGATCATCTGGACGGCGATCCCGTTCCTGATCCTGATCGGCATGGCCTT
TCCTGCCACCAAGACCGTGATTGCCATGAAGGATACGTCCAACCCGGACATCACGGTCAAGGCGACGGGTTATCAGTGGA
AATGGGGTTATGACTACCTGACGGGTGAAGGGGAGGGCATTGGTTTCCTGAGCGCCCTTGCCACGCCCAAGGCGCAGATC
GAGAATGCGGCGCCCAAGGGGGAGAATTATCTTCTGGAAGTGGACAAGCCCCTGGTGGTGCCGACGGGCAAGAAAGTGCG
CGTGCTGATCACTGCCAATGACGTGCTGCACGCCTGGTGGGTACCGGCGCTAGGCGTCAAGCAGGATGCCATCCCGGGCT
TCATCCGTGACGTGTGGTTCAACATCGAGAAGCCCGGCACCTATCGCGGCCAGTGCGCCGAGTTGTGCGGCAAGGAGCAT
GGCTTCATGCCGATCGTGGTAGAGGCGGTGGAGCCTGAGAAATACGCTGCCTGGGTGGCAGAGCAGAAAACCAAGCTGGC
GGCAGTGGCGGTGGACGTCAACAAGGAGTTCGGGCTGGACGAGCTCAAGGCCAAGGGCGAAGCGGTGTATAACGCCAACT
GCGCGGCCTGTCACCAGGCCAACGGGCAGGGCGTGCCCGGCACCTTCCCCGCCATCGCCGGATCGAAGGTTGCCACCGGG
CCCAAGGACGGCCACATCAATATCGTCATGAACGGCAAGAGCGGCACGGCAATGGCCCCATTCAAGCATCTGTCGGACGT
GGATATTGCCTCGGTGATCACCTATCAGCGCAATTCCTTCGGCAATTCGACGGGCGATGCCGTCCAGCCATCCGAAATCA
ATCAACACAGATAA

Upstream 100 bases:

>100_bases
ATGGAAATGTTCTGTCCGAAAGCATTGCGTAATGGGTCGAACATTGTGAGATTTTGGAAGATTGGCTCGTACTGTAATCA
GTAATCAAGTGGGGGGAAAT

Downstream 100 bases:

>100_bases
TAGCCTCAAGGAGGAAACCATGGCAGCAGTACACGATCACGACGTTGCACACGCCCACGATCATCATCCCACGGGCTTGA
TGCGTTGGCTGACTACCACG

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSSKAAAGVAGIVAVAWNSGLALAAADPYQLNLPEPQTVIAQQIYDQHTLVLWICLAIFVGVFGVMFYSVIQHRKSKGYK
AANFHHSTTVEIIWTAIPFLILIGMAFPATKTVIAMKDTSNPDITVKATGYQWKWGYDYLTGEGEGIGFLSALATPKAQI
ENAAPKGENYLLEVDKPLVVPTGKKVRVLITANDVLHAWWVPALGVKQDAIPGFIRDVWFNIEKPGTYRGQCAELCGKEH
GFMPIVVEAVEPEKYAAWVAEQKTKLAAVAVDVNKEFGLDELKAKGEAVYNANCAACHQANGQGVPGTFPAIAGSKVATG
PKDGHINIVMNGKSGTAMAPFKHLSDVDIASVITYQRNSFGNSTGDAVQPSEINQHR

Sequences:

>Translated_377_residues
MSSKAAAGVAGIVAVAWNSGLALAAADPYQLNLPEPQTVIAQQIYDQHTLVLWICLAIFVGVFGVMFYSVIQHRKSKGYK
AANFHHSTTVEIIWTAIPFLILIGMAFPATKTVIAMKDTSNPDITVKATGYQWKWGYDYLTGEGEGIGFLSALATPKAQI
ENAAPKGENYLLEVDKPLVVPTGKKVRVLITANDVLHAWWVPALGVKQDAIPGFIRDVWFNIEKPGTYRGQCAELCGKEH
GFMPIVVEAVEPEKYAAWVAEQKTKLAAVAVDVNKEFGLDELKAKGEAVYNANCAACHQANGQGVPGTFPAIAGSKVATG
PKDGHINIVMNGKSGTAMAPFKHLSDVDIASVITYQRNSFGNSTGDAVQPSEINQHR
>Mature_376_residues
SSKAAAGVAGIVAVAWNSGLALAAADPYQLNLPEPQTVIAQQIYDQHTLVLWICLAIFVGVFGVMFYSVIQHRKSKGYKA
ANFHHSTTVEIIWTAIPFLILIGMAFPATKTVIAMKDTSNPDITVKATGYQWKWGYDYLTGEGEGIGFLSALATPKAQIE
NAAPKGENYLLEVDKPLVVPTGKKVRVLITANDVLHAWWVPALGVKQDAIPGFIRDVWFNIEKPGTYRGQCAELCGKEHG
FMPIVVEAVEPEKYAAWVAEQKTKLAAVAVDVNKEFGLDELKAKGEAVYNANCAACHQANGQGVPGTFPAIAGSKVATGP
KDGHINIVMNGKSGTAMAPFKHLSDVDIASVITYQRNSFGNSTGDAVQPSEINQHR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=161, Percent_Identity=40.3726708074534, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6226540, Length=238, Percent_Identity=33.1932773109244, Blast_Score=145, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 40580; Mature: 40449

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSKAAAGVAGIVAVAWNSGLALAAADPYQLNLPEPQTVIAQQIYDQHTLVLWICLAIFV
CCCCCCCCHHEEEEEEECCCEEEEECCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHH
GVFGVMFYSVIQHRKSKGYKAANFHHSTTVEIIWTAIPFLILIGMAFPATKTVIAMKDTS
HHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
NPDITVKATGYQWKWGYDYLTGEGEGIGFLSALATPKAQIENAAPKGENYLLEVDKPLVV
CCCEEEEECCEEEEECCCEECCCCCCCCHHHHHCCCHHHHHCCCCCCCCEEEEECCCEEE
PTGKKVRVLITANDVLHAWWVPALGVKQDAIPGFIRDVWFNIEKPGTYRGQCAELCGKEH
ECCCEEEEEEEECCEEHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHCCCCC
GFMPIVVEAVEPEKYAAWVAEQKTKLAAVAVDVNKEFGLDELKAKGEAVYNANCAACHQA
CCEEEEEEECCCHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHCCCCEEECCCCCEEECC
NGQGVPGTFPAIAGSKVATGPKDGHINIVMNGKSGTAMAPFKHLSDVDIASVITYQRNSF
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCHHHCCCCCHHHHHEECCCCC
GNSTGDAVQPSEINQHR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSKAAAGVAGIVAVAWNSGLALAAADPYQLNLPEPQTVIAQQIYDQHTLVLWICLAIFV
CCCCCCCHHEEEEEEECCCEEEEECCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHH
GVFGVMFYSVIQHRKSKGYKAANFHHSTTVEIIWTAIPFLILIGMAFPATKTVIAMKDTS
HHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
NPDITVKATGYQWKWGYDYLTGEGEGIGFLSALATPKAQIENAAPKGENYLLEVDKPLVV
CCCEEEEECCEEEEECCCEECCCCCCCCHHHHHCCCHHHHHCCCCCCCCEEEEECCCEEE
PTGKKVRVLITANDVLHAWWVPALGVKQDAIPGFIRDVWFNIEKPGTYRGQCAELCGKEH
ECCCEEEEEEEECCEEHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHCCCCC
GFMPIVVEAVEPEKYAAWVAEQKTKLAAVAVDVNKEFGLDELKAKGEAVYNANCAACHQA
CCEEEEEEECCCHHHHHHHHHHCCEEEEEEEECCCCCCHHHHHCCCCEEECCCCCEEECC
NGQGVPGTFPAIAGSKVATGPKDGHINIVMNGKSGTAMAPFKHLSDVDIASVITYQRNSF
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEECCHHHCCCCCHHHHHEECCCCC
GNSTGDAVQPSEINQHR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2820725; 7651515; 9380672 [H]