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The map label for this gene is creB [H]

Identifier: 82546749

GI number: 82546749

Start: 4514202

End: 4514867

Strand: Direct

Name: creB [H]

Synonym: SBO_4461

Alternate gene names: 82546749

Gene position: 4514202-4514867 (Clockwise)

Preceding gene: 82546748

Following gene: 82546750

Centisome position: 99.88

GC content: 55.11

Gene sequence:

>666_bases
GTGGAAGATGAGCAAGGGATAGCCGACACGCTGGTCTACATGTTGCAGCAGGAAGGTTTTGCCGTCGAGGTCTTTGAGCG
AGGCTTGCCGGTGCTGGATAAAGCTCGCCAGCTGGTTCCCGACGTCATGATTCTCGACGTTGGTTTGCCTGATATCAGCG
GCTTTGAATTGTGCAGCCAGTTACTGGCGCTCCATCCGGCGTTACCTGTACTGTTCCTGACGGCCCGAAGTGAAGAGGTC
GATCGCCTGCTTGGGCTGGAAATTGGCGCTGACGACTATGTGGCTAAACCGTTTTCACCCCGCGAAGTGTGCGCCAGGGT
GCGCACCTTACTGCGTCGGGTGAAGAAGTTCTCGTCGCCGTCTCCCGTCATCCGTATTGGTCATTTTGAATTGAATGAAC
CCGCGGCGCAGATCAGCTGGTTTGACACGCCATTAACGCTGACGCGGTATGAGTTTTTATTGCTGAAGACGTTACTCAAG
TCGCCAGGCCGCGTCTGGTCCCGCCAGCAACTGATGGATAGCGTGTGGGAAGATGCGCAGGACACCTACGATCGCACCGT
TGATACCCACATTAAAACGTTGCATGCCAAGCTGCGTGCCATCAACCCCGATCTTTCACCGATTAATACTCATCGCGGCA
TGGGATATAGCCTGAGGGGCCTGTAA

Upstream 100 bases:

>100_bases
AGTTGTAGAAGGTTCGCCGAAAAACGCGATTAGCGCGGTTCCTGTCATGCCGTGGCGGCAATAACAGAGGCGATTTATAC
AACGGGAAACGGTCTGGTTA

Downstream 100 bases:

>100_bases
TGCGTATCGGCATGCGGTTGCTGCTGGGCTATTTTTTACTGGTGGCGGTGGCGGCCTGGTTCGTACTGGCTATTTTTGTC
AAAGAAGTTAAACCGGGCGT

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQLVPDVMILDVGLPDISGFELCSQLLALHPALPVLFLTARSEEV
DRLLGLEIGADDYVAKPFSPREVCARVRTLLRRVKKFSSPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEFLLLKTLLK
SPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLHAKLRAINPDLSPINTHRGMGYSLRGL

Sequences:

>Translated_221_residues
MEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQLVPDVMILDVGLPDISGFELCSQLLALHPALPVLFLTARSEEV
DRLLGLEIGADDYVAKPFSPREVCARVRTLLRRVKKFSSPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEFLLLKTLLK
SPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLHAKLRAINPDLSPINTHRGMGYSLRGL
>Mature_221_residues
MEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQLVPDVMILDVGLPDISGFELCSQLLALHPALPVLFLTARSEEV
DRLLGLEIGADDYVAKPFSPREVCARVRTLLRRVKKFSSPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEFLLLKTLLK
SPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLHAKLRAINPDLSPINTHRGMGYSLRGL

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=96.8325791855204, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1788394, Length=222, Percent_Identity=41.8918918918919, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=35.9090909090909, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=35, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1789809, Length=180, Percent_Identity=37.2222222222222, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=35.6164383561644, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787375, Length=216, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI2367329, Length=223, Percent_Identity=35.8744394618834, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=33.0357142857143, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=33.4862385321101, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=30.3964757709251, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=31.651376146789, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=26.9565217391304, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=138, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25026; Mature: 25026

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQLVPDVMILDVGLPDISGFELCSQ
CCCCCHHHHHHHHHHHHCCCEEHHHHCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHH
LLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLRRVKKFSSP
HHHHCCHHHHHEEECCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
SPVIRIGHFELNEPAAQISWFDTPLTLTRYEFLLLKTLLKSPGRVWSRQQLMDSVWEDAQ
CCEEEECCEECCCCHHHEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
DTYDRTVDTHIKTLHAKLRAINPDLSPINTHRGMGYSLRGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure
MEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQLVPDVMILDVGLPDISGFELCSQ
CCCCCHHHHHHHHHHHHCCCEEHHHHCCCCHHHHHHHHCCCEEEEECCCCCCCHHHHHHH
LLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLRRVKKFSSP
HHHHCCHHHHHEEECCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
SPVIRIGHFELNEPAAQISWFDTPLTLTRYEFLLLKTLLKSPGRVWSRQQLMDSVWEDAQ
CCEEEECCEECCCCHHHEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
DTYDRTVDTHIKTLHAKLRAINPDLSPINTHRGMGYSLRGL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]