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The map label for this gene is aceB [H]

Identifier: 82546351

GI number: 82546351

Start: 4073479

End: 4075080

Strand: Direct

Name: aceB [H]

Synonym: SBO_4034

Alternate gene names: 82546351

Gene position: 4073479-4075080 (Clockwise)

Preceding gene: 82546350

Following gene: 82546352

Centisome position: 90.12

GC content: 51.19

Gene sequence:

>1602_bases
ATGACTGAACAGGCAACAACAACCGATGAACTGGCTTTCACAAGGCCGTATGGCGAGCAGGAGAAGCAAATTCTTACTGC
CGAAGCGGTAGAATTTCTGACTGAGCTGGTGACGCATTTTACGCCACAACGAAATAAACTTCTGGCAGCGCGCATTCAGC
AGCAGCAAGATATTGATAACGGAACGTTGCCTGATTTTATTTCGGAAACAGCTTCCATTTGCGATGCTGATTGGAAAATT
CGCGGGATTCCTGCGGACTTAGAAGACCGCCGCGTAGAGATAACTGGCCCGGTAGAGCGCAAGATGGTGATCAACGCGCT
CAACGCCAATGTGAAAGTCTTTATGGCCGATTTCGAAGATTCACTGGCCCCGGACTGGAACAAAGTGATCGACGGGCAAA
TTAACCTGCGTGATGCAGTTAACGGTACCATCAGCTATACCAATGAAGCAGGCAAAATTTACCAGCTCAAGCCCAATCCA
GCGGTTTTGATTTGTCGGGTACGCGGTCTGCACTTGCCGGAAAAACATGTCACCTGGCGTGGTGAGGCAATCCCCGGCAG
CCTGTTTGATTTTGCGCTCTATTTCTTCCACAACTATCAGGCTCTGTTGGCAAAGGGCAGTGGTCCCTATTTCTATCTGC
CGAAAACCCAGTCCTGGCAGGAAGCGGCCTGGTGGAGCGAAGTCTTCAGCTATGCAGAAGATCGCTTTAATCTGCCGCGC
GGCACCATCAAGGCGACGTTGCTGATTGAAACGCTGCCCGCCGTGTTCCAGATGGATGAAATCCTTCACGCGCTGCGTGA
CCATATTGTTGGTCTGAACTGCGGTCGTTGGGATTACATCTTCAGCTATATCAAAACGTTGAAAAACTATCCCGATCGCG
TCCTGCCAGACAGACAGGCAGTGACGATGGATAAACCATTCCTGAATGCTTACTCACGCCTGTTGATTAAAACCTGCCAT
AAACGCGGTGCTTTTGCGATGGGCGGCATGGCGGCGTTTATTCCGAGCAAAGATGAAGAGCACAATAACCAGGTGCTCAA
CAAAGTAAAAGCGGATAAATCGCTGGAAGCCAATAACGGTCACGATGGCACATGGATCGCTCACCCAGGCCTTGCGGATA
CGGCAATGGCGGTATTCAACGACATTCTCGGCTCCCGTAAAAATCAGCTTGAAGTGATGCGCGAACAAGACGCGCCGATT
ACTGCCGATCAGCTACTGGCACCTTGTGACGGTGAACGCACCGAAGAAGGTATGCGCGCAAATATTCGCGTAGCCGTGCA
GTACATCGAAGCGTGGATCTCTGGCAACGGCTGTGTGCCGATTTATGGCCTGATGGAAGATGCGGCGACGGCTGAAATTT
CCCGTACCTCAATCTGGCAGTGGATCCATCATCAAAAAATGTTGAGCAATGGCAAACCGGTAACTAAAGCCTTGTTCCGC
CAGATGCTGGGCGAAGAGATGAAAGTCATTGCCAGCGAACTGGGCGAAGAACGTTTCTCCCAGGGGCGTTTTGGCGATGC
CGCACGCTTGATGGAACAGATCACCACTTCCGATGAGTTAATTGATTTCCTGACCCTGCCAGGCTACTGCCTGTTAGCGT
AA

Upstream 100 bases:

>100_bases
CATTTTAAATGAGTAGTCTTAGTTGTGCTGAACGAAAAGCGCACAACGATCCTTCGTTCACAGTGGGGAAGTTTTCGGAT
CCATGACGAGGAGCTGCACG

Downstream 100 bases:

>100_bases
ACCACCACATAACTATGGAGCATCTGCACATGAAAACCCGTACACAACAAATTGAAGAATTACAGAAAGAGTGGACTCAA
CCGCGTTGGGAAGGCATTAC

Product: malate synthase

Products: NA

Alternate protein names: MSA [H]

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MTEQATTTDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDNGTLPDFISETASICDADWKI
RGIPADLEDRRVEITGPVERKMVINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAEDRFNLPR
GTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCH
KRGAFAMGGMAAFIPSKDEEHNNQVLNKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDAPI
TADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKMLSNGKPVTKALFR
QMLGEEMKVIASELGEERFSQGRFGDAARLMEQITTSDELIDFLTLPGYCLLA

Sequences:

>Translated_533_residues
MTEQATTTDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDNGTLPDFISETASICDADWKI
RGIPADLEDRRVEITGPVERKMVINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAEDRFNLPR
GTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCH
KRGAFAMGGMAAFIPSKDEEHNNQVLNKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDAPI
TADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKMLSNGKPVTKALFR
QMLGEEMKVIASELGEERFSQGRFGDAARLMEQITTSDELIDFLTLPGYCLLA
>Mature_532_residues
TEQATTTDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDNGTLPDFISETASICDADWKIR
GIPADLEDRRVEITGPVERKMVINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNPA
VLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAEDRFNLPRG
TIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCHK
RGAFAMGGMAAFIPSKDEEHNNQVLNKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDAPIT
ADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKMLSNGKPVTKALFRQ
MLGEEMKVIASELGEERFSQGRFGDAARLMEQITTSDELIDFLTLPGYCLLA

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=533, Percent_Identity=99.249530956848, Blast_Score=1100, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561814, Length=513, Percent_Identity=51.0721247563353, Blast_Score=505, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI71982926, Length=410, Percent_Identity=53.6585365853659, Blast_Score=419, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6322222, Length=514, Percent_Identity=47.0817120622568, Blast_Score=437, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6324212, Length=529, Percent_Identity=45.3686200378072, Blast_Score=436, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 60140; Mature: 60009

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQATTTDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDN
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
GTLPDFISETASICDADWKIRGIPADLEDRRVEITGPVERKMVINALNANVKVFMADFED
CCCHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEEEECCCC
SLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNPAVLICRVRGLHLPEKHVTWR
CCCCCHHHHCCCCEEEHHHCCCCEEEECCCCEEEEECCCCEEEEEEECCCCCCCHHCCCC
GEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAEDRFNLPR
CCCCCCHHHHHHHHHHHCCHHEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
GTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCE
VTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFIPSKDEEHNNQVLNKVKADKSLEANNG
EECCCHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCC
HDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDAPITADQLLAPCDGERTEEGMRA
CCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCC
NIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKMLSNGKPVTKALFR
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QMLGEEMKVIASELGEERFSQGRFGDAARLMEQITTSDELIDFLTLPGYCLLA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCCEEECC
>Mature Secondary Structure 
TEQATTTDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDN
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
GTLPDFISETASICDADWKIRGIPADLEDRRVEITGPVERKMVINALNANVKVFMADFED
CCCHHHHHHHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEEEECCCC
SLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNPAVLICRVRGLHLPEKHVTWR
CCCCCHHHHCCCCEEEHHHCCCCEEEECCCCEEEEECCCCEEEEEEECCCCCCCHHCCCC
GEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAEDRFNLPR
CCCCCCHHHHHHHHHHHCCHHEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
GTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCE
VTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFIPSKDEEHNNQVLNKVKADKSLEANNG
EECCCHHHHHHHHHHHHHHHHCCCEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCC
HDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDAPITADQLLAPCDGERTEEGMRA
CCCCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCC
NIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKMLSNGKPVTKALFR
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QMLGEEMKVIASELGEERFSQGRFGDAARLMEQITTSDELIDFLTLPGYCLLA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3050899; 3060852; 8265357; 9278503 [H]