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The map label for this gene is yifK [H]

Identifier: 82546151

GI number: 82546151

Start: 3830373

End: 3831758

Strand: Direct

Name: yifK [H]

Synonym: SBO_3807

Alternate gene names: 82546151

Gene position: 3830373-3831758 (Clockwise)

Preceding gene: 82546150

Following gene: 82546152

Centisome position: 84.75

GC content: 53.32

Gene sequence:

>1386_bases
ATGGCAGATAACAAACCAGAGCTACAGCGTGGGCTGGAAGCTCGACATATCGAACTCATCGCCCTGGGGGGCACCATTGG
CGTCGGCCTGTTTATGGGGGCCGCCAGTACCTTGAAATGGGCCGGGCCATCCGTATTGTTGGCCTATATCATCGCCGGGC
TATTCGTCTTTTTCATCATGCGTTCAATGGGCGAAATGTTGTTCCTCGAACCGGTTACCGGTTCGTTCGCCGTTTATGCG
CATCGTTATATGAGCCCGTTCTTTGGTTATCTCACCGCCTGGTCTTATTGGTTTATGTGGATGGCGGTGGGGATCTCAGA
AATCACCGCCGTTGGCGTTTATGTCCAGTTCTGGTTCCCGGAGATGGCGCAGTGGATACCCGCATTGATCGCAGTGGCGC
TGGTGGCGTTGGCGAATCTGGCGGCGGTGCGGTTGTACGGCGAAATCGAGTTCTGGTTCGCGATGATCAAAGTCACCACG
ATTATCGTGATGATTGTCATTGGCCTGGGCGTGATTTTCTTTGGCTTTGGCAATGGCGGGCAGTCGATTGGTTTTAGCAA
TCTCACAGAGCATGGCGGTTTCTTTGCGGGTGGCTGGAAAGGGTTCCTGACCGCGCTGTGTATTGTGGTGGCGTCCTACC
AGGGCGTGGAGCTGATTGGCATTACTGCCGGTGAAGCGAAGAATCCGCAGGTGACGTTGCGCAGTGCCGTAGGCAAAGTG
CTGTGGCGGATCCTGATTTTCTACGTAGGCGCGATTTTCGTTATCGTCACCATCTTCCCGTGGAATGAAAGTGGCAGCAA
CGGCAGCCCGTTCGTACTGACTTTTGCCAAAATCGGTATTACCGCAGCGGCGGGCATTATCAACTTTGTGGTGCTGACGG
CTGCGCTCTCTGGCTGTAACAGCGGCATGTACAGTTGCGGACGTATGCTCTACGCACTGGCGAAAAACCGTCAGTTACCG
GCGGCGATGGCGAAAGTTTCCCGTCACGGCGTACCAGTTGCGGGTGTGGCAGTATCTATTGCTATTCTGCTAATTGGCTC
ATGCCTGAACTACATCATTCCCAATCCGCAGCGTGTGTTTGTCTACGTCTACAGTGCCAGCGTGCTTCCGGGGATGGTGC
CATGGTTTGTGATATTGATAAGCCAGCTGCGTTTTCGGCGTGCACATAAAGCGGCGATTGCCAGCCATCCGTTCCGCTCA
ATCCTGTTCCCGTGGGCCAACTACGTAACAATGGCATTCCTGATTTGCGTTTTGATCGGCATGTACTTTAATGAAGATAC
GCGTATGTCGCTGTTTGTTGGCATCATCTTTATGCTGGCGGTGACGGCGATTTATAAAGTTTTTGGCCTTAATCGCCACG
GGAAAGCGCATAAACTGGAGGAATAA

Upstream 100 bases:

>100_bases
TTGCCATTTCTCCTGAATTACGAAAACATTCGCAACACTCGATGTACCCATAACGATAACCGGTAACACCGGAAAGCATG
CAAACACAACACGAGGATTT

Downstream 100 bases:

>100_bases
GCAGCAAAACGCACAAACCGTAACCAAACGCGCAATTTATTTAAAAAGGGACTAGACAGAGGGGTGGGAAGTCCGTATTA
TCCACCCCCGCAACGGCGCT

Product: transport protein YifK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAVGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWNESGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRS
ILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLEE

Sequences:

>Translated_461_residues
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAVGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWNESGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRS
ILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLEE
>Mature_460_residues
ADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAH
RYMSPFFGYLTAWSYWFMWMAVGISEITAVGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTI
IVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVL
WRILIFYVGAIFVIVTIFPWNESGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPA
AMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSI
LFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLEE

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994972, Length=461, Percent_Identity=99.5661605206074, Blast_Score=916, Evalue=0.0,
Organism=Escherichia coli, GI1786789, Length=429, Percent_Identity=44.0559440559441, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1786302, Length=431, Percent_Identity=40.3712296983759, Blast_Score=342, Evalue=4e-95,
Organism=Escherichia coli, GI1786602, Length=460, Percent_Identity=44.7826086956522, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1790653, Length=464, Percent_Identity=38.3620689655172, Blast_Score=334, Evalue=7e-93,
Organism=Escherichia coli, GI87081915, Length=392, Percent_Identity=39.5408163265306, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI1788480, Length=435, Percent_Identity=38.8505747126437, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI87081708, Length=471, Percent_Identity=36.7303609341826, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1789017, Length=464, Percent_Identity=32.9741379310345, Blast_Score=254, Evalue=9e-69,
Organism=Escherichia coli, GI2367353, Length=460, Percent_Identity=25, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324061, Length=438, Percent_Identity=35.1598173515982, Blast_Score=236, Evalue=8e-63,
Organism=Saccharomyces cerevisiae, GI6320772, Length=439, Percent_Identity=34.8519362186788, Blast_Score=222, Evalue=9e-59,
Organism=Saccharomyces cerevisiae, GI6324924, Length=414, Percent_Identity=32.3671497584541, Blast_Score=202, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6324990, Length=447, Percent_Identity=30.4250559284116, Blast_Score=192, Evalue=6e-50,
Organism=Saccharomyces cerevisiae, GI6322892, Length=437, Percent_Identity=30.8924485125858, Blast_Score=190, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6324059, Length=439, Percent_Identity=33.0296127562642, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6322967, Length=415, Percent_Identity=30.6024096385542, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6321629, Length=404, Percent_Identity=28.4653465346535, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6319824, Length=436, Percent_Identity=27.9816513761468, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6321053, Length=421, Percent_Identity=29.2161520190024, Blast_Score=167, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6319608, Length=422, Percent_Identity=29.1469194312796, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6324981, Length=410, Percent_Identity=30.7317073170732, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6319543, Length=400, Percent_Identity=29.25, Blast_Score=158, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324553, Length=397, Percent_Identity=30.7304785894207, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6319542, Length=403, Percent_Identity=27.0471464019851, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6320717, Length=404, Percent_Identity=25.4950495049505, Blast_Score=149, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6320251, Length=400, Percent_Identity=26, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320364, Length=555, Percent_Identity=23.7837837837838, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI221512776, Length=360, Percent_Identity=21.9444444444444, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24666159, Length=360, Percent_Identity=21.9444444444444, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50360; Mature: 50228

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCCCHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAVGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTIIVMIVIGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CCCCCCCHHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWNESGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSILFPWANYVTMAFLICVLIG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLEE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCCHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAVGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTTIIVMIVIGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CCCCCCCHHHCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWNESGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRSILFPWANYVTMAFLICVLIG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLEE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]