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The map label for this gene is rtcR [H]

Identifier: 82545778

GI number: 82545778

Start: 3401056

End: 3402654

Strand: Direct

Name: rtcR [H]

Synonym: SBO_3410

Alternate gene names: 82545778

Gene position: 3401056-3402654 (Clockwise)

Preceding gene: 82545775

Following gene: 82545782

Centisome position: 75.25

GC content: 54.53

Gene sequence:

>1599_bases
ATGCGTAAAACAGTAGCTTTTGGCTTTGTCGGAACGGTGCTGGATTATGCCGGGCGCGGCAGTCAGCGCTGGTCAAAATG
GCATCCGACACTCTGTTTATGCCAGCAAGAATCGTTGGTCATCGATCGACTGGAATTATTGCATGACGCCCGCTCGTGCT
CGCTATTTGAAACGCTTAAACGCGATATCGCCAGCGTTTCGCCAGAAACAGAAGTGGTGAGCATTGAGATTGAACTGCAT
AACCCGTGGGATTTCGAAGAGGTTTACGCCTGCCTGCATGATTTCGCCCGTGGTTACAAGTTTCAGCCAGAAAAAGAAGA
CTATTTAATTCACATCACCACCGGCACCCACGTCGCGCAGATTTGCTGGTTTCTGCTGGCGGAAGCGCGTTATCTACCCG
CCCGGTTGATACAAACTTCACCACCGCGCAAAAAAGAACAACCGCGCGGTGCCGGTGAAGTGACGATTATCGATCTCGAT
CTAAGCCGTTATAACGCCATCGCCAGCCGCTTTGCCGAGGAACGCCAGCAAACGCTTGATTTTCTTAAGTCCGGCATTGC
CACGCGTAACCCCCACTTCAACCGCATGATTGAGCAGATTGAAAAAGTGGCGATTAAATCCCGCGCACCGATCCTGCTTA
ACGGCCCAACCGGTGCGGGAAAGTCATTTCTGGCGCGACGTATATTTGAATTAAAACAGGCGCGGCATCAGTTTAGCGGC
GCGTTTGTGGAAGTGAACTGCGCCACCCTGCGCGGCGATACCGCCATGTCGACGCTGTTTGGTCATGTGAAAGGCGCGTT
TACCGGGGCGCGGGAATCTCGTGAAGGTTTATTACGCAGCGCCAACGGCGGAATGTTGTTTTTTGATGAGATTGGCGAAC
TGGGCGCAGACGAACAGGCAATGCTGCTAAAAGCCATTGAAGAGAAAACCTTTTACCCGTTTGGCAGCGATCGCCAGGTG
AGCAGTGATTTTCAGCTTATCGCCGGAACGGTGCGCGATTTGCGCCAGCTGGTTGCCGAAGGCAAATTTCGCGAAGATCT
GTACGCGCGGATCAATCTCTGGACCTTCACCCTGCCGGGTCTACGCCAGCGCCAGGAAGATATTGAACCGAACCTTGATT
ATGAAGTGGAGCGCCACGCCACACTCACTGGCGACAGCGTGCGTTTTAACACCGAAGCGCGGCGCGCCTGGTTGGCTTTT
GCGACCTCTCCCCAGGCAACATGGCGCGGTAACTTTCGCGAACTTTCTGCCAGCGTCACGCGGATGGCCACCTTTGCCAC
TAGCGGACGCATCACTCTGGACGTGGTTGAAGATGAGATAAACCGTCTGCGCTATAACTGGCAGGAGAGCCGCCCCTCCG
CGCTTACGGCGTTGCTGGGCGCAGAGGCAGAAAACATCGATCTCTTCGACCGTATGCAACTGGAACACGTTATCGCTATC
TGCCGCCAGGCAAAGTCGCTTTCTGCAACCGGACGACAGCTTTTTGATGTTTCGCGCCAGGGAAAAGCCAGCGTCAATGA
CGCGGATCGGCTACGCAAATACCTGGCGCGTTTTGGTCTGACGTGGGAAGCCGTGCAGGATCAGCACAGCTCCAGTTGA

Upstream 100 bases:

>100_bases
TTGTTTTTAAAAAGATTATATCTTTATGTCCGTAACCGGAGATTTCCCGCAAAGCCGATTTACCGATAATGAAATATCGT
CTTTTATAAGGATATCTAAG

Downstream 100 bases:

>100_bases
ATATGATGGTCCGTCAGCACCTGCATTACGCTTACTGGCGGCGGGGCGTCGGTGTAGACGGCATCTACCATGCTGATGCT
GCCCATATTGACCATCGCGT

Product: 2-component regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MRKTVAFGFVGTVLDYAGRGSQRWSKWHPTLCLCQQESLVIDRLELLHDARSCSLFETLKRDIASVSPETEVVSIEIELH
NPWDFEEVYACLHDFARGYKFQPEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQTSPPRKKEQPRGAGEVTIIDLD
LSRYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTGAGKSFLARRIFELKQARHQFSG
AFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREGLLRSANGGMLFFDEIGELGADEQAMLLKAIEEKTFYPFGSDRQV
SSDFQLIAGTVRDLRQLVAEGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHATLTGDSVRFNTEARRAWLAF
ATSPQATWRGNFRELSASVTRMATFATSGRITLDVVEDEINRLRYNWQESRPSALTALLGAEAENIDLFDRMQLEHVIAI
CRQAKSLSATGRQLFDVSRQGKASVNDADRLRKYLARFGLTWEAVQDQHSSS

Sequences:

>Translated_532_residues
MRKTVAFGFVGTVLDYAGRGSQRWSKWHPTLCLCQQESLVIDRLELLHDARSCSLFETLKRDIASVSPETEVVSIEIELH
NPWDFEEVYACLHDFARGYKFQPEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQTSPPRKKEQPRGAGEVTIIDLD
LSRYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTGAGKSFLARRIFELKQARHQFSG
AFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREGLLRSANGGMLFFDEIGELGADEQAMLLKAIEEKTFYPFGSDRQV
SSDFQLIAGTVRDLRQLVAEGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHATLTGDSVRFNTEARRAWLAF
ATSPQATWRGNFRELSASVTRMATFATSGRITLDVVEDEINRLRYNWQESRPSALTALLGAEAENIDLFDRMQLEHVIAI
CRQAKSLSATGRQLFDVSRQGKASVNDADRLRKYLARFGLTWEAVQDQHSSS
>Mature_532_residues
MRKTVAFGFVGTVLDYAGRGSQRWSKWHPTLCLCQQESLVIDRLELLHDARSCSLFETLKRDIASVSPETEVVSIEIELH
NPWDFEEVYACLHDFARGYKFQPEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQTSPPRKKEQPRGAGEVTIIDLD
LSRYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTGAGKSFLARRIFELKQARHQFSG
AFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREGLLRSANGGMLFFDEIGELGADEQAMLLKAIEEKTFYPFGSDRQV
SSDFQLIAGTVRDLRQLVAEGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHATLTGDSVRFNTEARRAWLAF
ATSPQATWRGNFRELSASVTRMATFATSGRITLDVVEDEINRLRYNWQESRPSALTALLGAEAENIDLFDRMQLEHVIAI
CRQAKSLSATGRQLFDVSRQGKASVNDADRLRKYLARFGLTWEAVQDQHSSS

Specific function: Transcriptional repressor of the rtcAB genes. Interacts with sigma-54 [H]

COG id: COG4650

COG function: function code KT; Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789828, Length=532, Percent_Identity=98.1203007518797, Blast_Score=1077, Evalue=0.0,
Organism=Escherichia coli, GI1788905, Length=275, Percent_Identity=35.6363636363636, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788550, Length=252, Percent_Identity=37.6984126984127, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790437, Length=256, Percent_Identity=39.0625, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789233, Length=256, Percent_Identity=35.546875, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87082117, Length=237, Percent_Identity=37.1308016877637, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1789087, Length=287, Percent_Identity=34.1463414634146, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787583, Length=244, Percent_Identity=35.655737704918, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87082152, Length=247, Percent_Identity=36.0323886639676, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790299, Length=241, Percent_Identity=35.2697095435685, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786524, Length=239, Percent_Identity=35.1464435146443, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87081872, Length=254, Percent_Identity=32.6771653543307, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87081858, Length=242, Percent_Identity=29.3388429752066, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR002078
- InterPro:   IPR009715
- InterPro:   IPR017183 [H]

Pfam domain/function: PF06956 RtcR; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 60341; Mature: 60341

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTVAFGFVGTVLDYAGRGSQRWSKWHPTLCLCQQESLVIDRLELLHDARSCSLFETLK
CCCEEEHHHHHHHHHHCCCCCCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
RDIASVSPETEVVSIEIELHNPWDFEEVYACLHDFARGYKFQPEKEDYLIHITTGTHVAQ
HHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHH
ICWFLLAEARYLPARLIQTSPPRKKEQPRGAGEVTIIDLDLSRYNAIASRFAEERQQTLD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
FLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTGAGKSFLARRIFELKQARHQFSG
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
AFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREGLLRSANGGMLFFDEIGELGADEQA
CEEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEHHHHHCCCCCHHH
MLLKAIEEKTFYPFGSDRQVSSDFQLIAGTVRDLRQLVAEGKFREDLYARINLWTFTLPG
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEEEECCC
LRQRQEDIEPNLDYEVERHATLTGDSVRFNTEARRAWLAFATSPQATWRGNFRELSASVT
HHHHHHCCCCCCCCEECCCEEECCCCEEECHHHHHEEEEEECCCCCHHCCCHHHHHHHHH
RMATFATSGRITLDVVEDEINRLRYNWQESRPSALTALLGAEAENIDLFDRMQLEHVIAI
HHHHHCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
CRQAKSLSATGRQLFDVSRQGKASVNDADRLRKYLARFGLTWEAVQDQHSSS
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCC
>Mature Secondary Structure
MRKTVAFGFVGTVLDYAGRGSQRWSKWHPTLCLCQQESLVIDRLELLHDARSCSLFETLK
CCCEEEHHHHHHHHHHCCCCCCCHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
RDIASVSPETEVVSIEIELHNPWDFEEVYACLHDFARGYKFQPEKEDYLIHITTGTHVAQ
HHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHH
ICWFLLAEARYLPARLIQTSPPRKKEQPRGAGEVTIIDLDLSRYNAIASRFAEERQQTLD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
FLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTGAGKSFLARRIFELKQARHQFSG
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
AFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREGLLRSANGGMLFFDEIGELGADEQA
CEEEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEHHHHHCCCCCHHH
MLLKAIEEKTFYPFGSDRQVSSDFQLIAGTVRDLRQLVAEGKFREDLYARINLWTFTLPG
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHEEEEEEEECCC
LRQRQEDIEPNLDYEVERHATLTGDSVRFNTEARRAWLAFATSPQATWRGNFRELSASVT
HHHHHHCCCCCCCCEECCCEEECCCCEEECHHHHHEEEEEECCCCCHHCCCHHHHHHHHH
RMATFATSGRITLDVVEDEINRLRYNWQESRPSALTALLGAEAENIDLFDRMQLEHVIAI
HHHHHCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
CRQAKSLSATGRQLFDVSRQGKASVNDADRLRKYLARFGLTWEAVQDQHSSS
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3045764; 7984428; 7920643; 9738023 [H]