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The map label for this gene is degQ [H]

Identifier: 82545537

GI number: 82545537

Start: 3160366

End: 3161733

Strand: Reverse

Name: degQ [H]

Synonym: SBO_3155

Alternate gene names: 82545537

Gene position: 3161733-3160366 (Counterclockwise)

Preceding gene: 82545538

Following gene: 82545536

Centisome position: 69.95

GC content: 51.75

Gene sequence:

>1368_bases
ATGAAAAAACAAACCCAGCTGTTGAGTGCATTAGCGTTAAGTGTCGGGTTAACTCTCTCGGCGTCATTTCAGGCCGTCGC
GTCGATTCCAGGCCAGGTTGCCGATCAGGCCCCTCTCCCCAGTCTGGCTCCAATGCTGGAAAAAGTGCTTCCGGCAGTGG
TGAGCGTACGGGTGGAAGGAACGGCCAGTCAGGGACAGAAAATCCCGGAAGAATTCAAAAAGTTTTTTGGTGATGATTTA
CCGGATCAACCTGCACAACCCTTCGAAGGTTTAGGTTCCGGTGTCATCATCAACGCCAGTAAAGGCTATGTGCTGACCAA
CAACCATGTGATTAATCAGGCACAGAAAATCAGTATTCAGCTCAATGATGGGCGCGAGTTTGATGCAAAACTGATTGGTA
GCGATGACCAGAGCGATATCGCCCTGTTACAAATTCAAAACCCGAGCAAATTAACGCAAATCGCTATTGCCGACTCCGAT
AAATTGCGCGTCGGTGATTTTGCCGTAGCGGTCGGTAACCCATTTGGCCTTGGGCAAACCGCCACCTCTGGCATTGTTTC
CGCATTAGGCCGCAGCGGGTTGAATCTTGAAGGTCTGGAAAACTTTATCCAGACAGATGCTTCCATTAACCGCGGTAACT
CCGGCGGTGCACTATTAAACCTTAACGGTGAGTTAATTGGCATCAACACTGCAATCCTTGCGCCTGGCGGCGGGAGCGTC
GGGATTGGATTTGCCATCCCCAGTAATATGGCGCGAACACTGGCGCAGCAGCTTATCGACTTTGGTGAAATCAAACGCGG
TTTGTTAGGCATCAAAGGCACCGAGATGAGTGCCGATATCGCCAAAGCCTTCAACCTTGACGTGCAGCGTGGCGCGTTTG
TCAGCGAAGTGTTGCCAGGTTCTGGCTCGGCAAAAGCGGGCGTCAAAGCGGGCGATATTATTACCAGCCTCAACGGCAAA
CCGCTGAATAGCTTTGCTGAGTTGCGCTCTCGTATCGCGACTACAGAGCCGGGCACGAAAGTGAAGCTTGGCCTGCTGCG
TAACGGCAAACCACTGGAAGTAGAAGTGACGCTTGATACCAGCACCTCTTCGTCGGCCAGCGCTGAAATGATCACGCCAG
CGCTGGAAGGTGCAACGTTGAGCGATGGTCAGCTAAAAGATTGCGGCAAAGGTATTAAGATCGATGAAGTTGTCAAAGGA
AGCCCAGCTGCTCAGGCAGGCTTGCAAAAAGACGATGTGATCATTGGCGTCAACCGCGATCGGGTGAACTCGATTGCTGA
AATGCGTAAAGTGCTGGCGGCAAAACCGGCCATCATCGCCCTGCAAATTGTACGCGGCAATGAAAGCATCTATCTGCTGA
TGCGTTAA

Upstream 100 bases:

>100_bases
TCATTTAATCTGGTGTCTCATTGTTAGCCGTCTGAAAATTCAATAACATCAAACTGTTTTGAATCTCTTTTCTTATCATT
CAGGTACGAGAGCAGGAATA

Downstream 100 bases:

>100_bases
TGTCGTAAACCGGGCATCAGGCTTACGTGTGATGTCCGGTTAACTCGTGGTATGCTGCTGCCGTTCCCTTTTTTAATGAC
GCCTCCATCATGTTTGTGAA

Product: serine endoprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDL
PDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGK
PLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDCGKGIKIDEVVKG
SPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESIYLLMR

Sequences:

>Translated_455_residues
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDL
PDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGK
PLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDCGKGIKIDEVVKG
SPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESIYLLMR
>Mature_455_residues
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDL
PDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGK
PLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDCGKGIKIDEVVKG
SPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESIYLLMR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=316, Percent_Identity=36.3924050632911, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4506141, Length=294, Percent_Identity=35.7142857142857, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI24308541, Length=305, Percent_Identity=30.8196721311475, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI7019477, Length=296, Percent_Identity=33.7837837837838, Blast_Score=133, Evalue=3e-31,
Organism=Escherichia coli, GI1789629, Length=455, Percent_Identity=99.7802197802198, Blast_Score=887, Evalue=0.0,
Organism=Escherichia coli, GI1786356, Length=440, Percent_Identity=57.9545454545455, Blast_Score=505, Evalue=1e-144,
Organism=Escherichia coli, GI1789630, Length=271, Percent_Identity=44.6494464944649, Blast_Score=209, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=32.5259515570934, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 47252; Mature: 47252

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEG
CCHHHHHHHHHHHHHCCEEECCHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHEEEEEEC
TASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQ
CHHCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCCEECCEEEEEEE
LNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQT
ECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECEEEEEECCCCCCCCH
ATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCE
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPG
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCC
SGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDT
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEEC
STSSSASAEMITPALEGATLSDGQLKDCGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRD
CCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHCCCCHHHCCCCCCCEEEECCHH
RVNSIAEMRKVLAAKPAIIALQIVRGNESIYLLMR
HHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEC
>Mature Secondary Structure
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEG
CCHHHHHHHHHHHHHCCEEECCHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHEEEEEEC
TASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQ
CHHCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCEEEECCCCEEEECCCEECCEEEEEEE
LNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQT
ECCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCEEECEEEEEECCCCCCCCH
ATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
HHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCCE
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPG
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCC
SGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDT
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEEEC
STSSSASAEMITPALEGATLSDGQLKDCGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRD
CCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHCCCCHHHCCCCCCCEEEECCHH
RVNSIAEMRKVLAAKPAIIALQIVRGNESIYLLMR
HHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]