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The map label for this gene is exuT [H]

Identifier: 82545348

GI number: 82545348

Start: 2962541

End: 2963959

Strand: Direct

Name: exuT [H]

Synonym: SBO_2954

Alternate gene names: 82545348

Gene position: 2962541-2963959 (Clockwise)

Preceding gene: 82545345

Following gene: 82545355

Centisome position: 65.55

GC content: 54.05

Gene sequence:

>1419_bases
ATGGCAACGTTCGGGGCGTGCCGGTTTTTTTTCGGTTACCCGGTCGTAACTAACATCTTCAGCCTCTGGCGGGATGATGG
CCGCGCTTCCTGCGGATATAACAAAACGATGAGGTTTTACATGCGTAAAATTAAAGGGTTACGTTGGTATATGATCGCAC
TGGTGACGCTTGGCACCGTGCTTGGTTACCTGACGCGTAACACTGTGGCGGCAGCTGCGCCAACTCTGATGGAAGAGTTA
AACATCTCCACCCAACAGTATTCCTATATCATCGCAGCCTATTCTGCTGCTTATACGGTCATGCAACCGGTAGCGGGCTA
TGTACTGGATGTGCTGGGTACGAAAATCGGTTATGCAATGTTTGCTGTACTGTGGGCCGTATTCTGTGGTGCAACCGCGC
TGGCTGGTAGCAGGGGTGGCCTGGCGATTGCTCGTGGTGCAGTCGGTGCCGCGGAAGCAGCGATGATCCCGGCGGGTCTG
AAAGCCAGCTCCGAATGGTTCCCGGCGAAAGAGCGTTCCATCGCGGTAGGTTACTTTAACGTAGGTTCTTCGATTGGTGC
GATGATTGCGCCGCCGCTGGTGGTATGGGCAATCGTAATGCACAGCTGGCAGATGGCATTTATCATCTCCGGTGCATTGA
GCTTTATCTGGGCGATGGCATGGCTGATTTTCTATAAACATCCGCGCGACCAGAAGCATCTGACCGATGAAGAACGCGAC
TATATTATTAATGGTCAGGAAGCCCAGCACCAGGTGAGCACGGCGAAGAAAATGTCCGTTGGTCAGATCCTGCGTAACCG
TCAGTTCTGGGGTATCGCGCTGCCGCGTTTCCTGGCAGAACCAGCCTGGGGTACTTTTAACGCGTGGATCCCGCTGTTCA
TGTTTAAAGTTTACGGCTTTAACCTGAAAGAGATCGCGATGTTCGCCTGGATGCCGATGCTGTTTGCTGACCTCGGTTGT
ATCCTCGGTGGTTACCTGCCGCCGCTGTTCCAGCGTTGGTTTGGTGTGAACCTGATCGTTTCCCGTAAGATGGTCGTAAC
GCTGGGTGCAGTGCTGATGATTGGCCCGGGTATGATCGGCCTGTTCACCAACCCGTATGTCGCAATTATGCTGCTGTGTA
TCGGTGGTTTTGCTCACCAGGCACTGTCTGGCGCGCTGATTACGCTCTCTTCTGACGTGTTCGGTCGTAACGAAGTGGCG
ACGGCGAACGGTTTAACCGGGATGTCCGCATGGCTGGCAAGTACGCTGTTTTCGCTGGTTGTCGGTGCACTGGCTGACAC
CATCGGCTTCAGCCCGCTGTTCGCAGTACTGGCAGTGTTCGACCTGTTAGGTGCGCTGGTTATCTGGACCGTGTTGCAGA
ACAAACCGGCGATTGAGGTAGCGCAGGAATCACATAACGATCCCGCACCGCAACATTAA

Upstream 100 bases:

>100_bases
GTCGCAAATCATAAGTCGACGGAATGCAAATTGCCGATTCATTCATTTGTTAGATGAATCGGGTTAACCGGTACGGAAGC
CGAATTAGCACGAAACTTTC

Downstream 100 bases:

>100_bases
CGTTTAACGTAAGTTATAACGACGAAGCCGCCTTATCAGGCGGCTTCGTCGTTTATATAGAAAAAAGCGTTTGTCCGCTT
TGCAGGGTTAATTGATGGTT

Product: transport of hexuronates

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MATFGACRFFFGYPVVTNIFSLWRDDGRASCGYNKTMRFYMRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEEL
NISTQQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSRGGLAIARGAVGAAEAAMIPAGL
KASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERD
YIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGC
ILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVA
TANGLTGMSAWLASTLFSLVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAIEVAQESHNDPAPQH

Sequences:

>Translated_472_residues
MATFGACRFFFGYPVVTNIFSLWRDDGRASCGYNKTMRFYMRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEEL
NISTQQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSRGGLAIARGAVGAAEAAMIPAGL
KASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERD
YIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGC
ILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVA
TANGLTGMSAWLASTLFSLVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAIEVAQESHNDPAPQH
>Mature_471_residues
ATFGACRFFFGYPVVTNIFSLWRDDGRASCGYNKTMRFYMRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELN
ISTQQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSRGGLAIARGAVGAAEAAMIPAGLK
ASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDY
IINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCI
LGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVAT
ANGLTGMSAWLASTLFSLVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAIEVAQESHNDPAPQH

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=383, Percent_Identity=22.976501305483, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI148743791, Length=254, Percent_Identity=24.0157480314961, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI154800443, Length=409, Percent_Identity=23.4718826405868, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI2367193, Length=472, Percent_Identity=99.1525423728814, Blast_Score=952, Evalue=0.0,
Organism=Escherichia coli, GI87082320, Length=410, Percent_Identity=26.8292682926829, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI2367379, Length=310, Percent_Identity=28.3870967741935, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1789515, Length=407, Percent_Identity=25.5528255528256, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789152, Length=382, Percent_Identity=23.8219895287958, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87082071, Length=439, Percent_Identity=23.6902050113895, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17552542, Length=318, Percent_Identity=24.8427672955975, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24580790, Length=242, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550460, Length=415, Percent_Identity=26.2650602409639, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24639764, Length=456, Percent_Identity=21.7105263157895, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129235, Length=276, Percent_Identity=26.4492753623188, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24655255, Length=382, Percent_Identity=27.7486910994764, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641682, Length=367, Percent_Identity=23.1607629427793, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51558; Mature: 51427

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATFGACRFFFGYPVVTNIFSLWRDDGRASCGYNKTMRFYMRKIKGLRWYMIALVTLGTV
CCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAM
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAVLWAVFCGATALAGSRGGLAIARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFN
HHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEE
VGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
YIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGF
EEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
NLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHH
LFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFSLV
HHCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKPAIEVAQESHNDPAPQH
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]